Publications

• Fleming AM & Mathewson NJ (2021). Nanopore Dwell Time Analysis Permits Sequencing and Conformational Assignment of Pseudouridine in SARS-CoV-2. ACS central science. Vol. 7, 1707-1717. Published, 11/01/2021.
• Ghude P & Schallenberger MA (2021). Comparison of Transition Metal-Mediated Oxidation Reactions of Guanine in Nucleoside and Single-Stranded Oligodeoxynucleotide Contexts. Inorganica chimica acta. Vol. 369, 240-246. Published, 10/01/2021.
• Wolna AH, Fleming AM & An N (2021). Electrical Current Signatures of DNA Base Modifications in Single Molecules Immobilized in the α-Hemolysin Ion Channel. Israel journal of chemistry. Vol. 53, 417-430. Published, 10/01/2021.
• Chen X & Fleming AM (2021). Endonuclease and Exonuclease Activities on Oligodeoxynucleotides Containing Spiroiminodihydantoin Depend on the Sequence Context and the Lesion Stereochemistry. New journal of chemistry = Nouveau journal de chimie. Vol. 37, 3440-3449. Published, 10/01/2021.
• Wolna AH (2021). Single-molecule detection of a guanine(C8) - thymine(N3) cross-link using ion channel recording. Journal of physical organic chemistry. Vol. 27, 247-251. Published, 10/01/2021.
• Fleming AM (2021). Bedside Mediastinotomy for Tension Pneumomediastinum With Tamponade in COVID-19. (pp. e265-e266). Vol. 112. The Annals of thoracic surgery. Published, 10/01/2021.
• Rogers RA, Meyer MR & Stewart KM (2021). Hysteresis in poly-2'-deoxycytidine i-motif folding is impacted by the method of analysis as well as loop and stem lengths. Biopolymers. Vol. 112, e23389. Published, 10/01/2021.
• Fleming AM (2021). Deciphering nucleic acid knots. Nature chemistry. Vol. 13, 618-619. Published, 09/01/2021.
• Jara-Espejo M (2021). Potential G-Quadruplex Forming Sequences and N6-Methyladenosine Colocalize at Human Pre-mRNA Intron Splice Sites. ACS chemical biology. Vol. 15, 1292-1300. Published, 04/01/2021.
• Fleming AM (2021). On the irrelevancy of hydroxyl radical to DNA damage from oxidative stress and implications for epigenetics. Chemical Society reviews. Vol. 49, 6524-6528. Published, 04/01/2021.
• Fleming AM (2021). Iron Fenton oxidation of 2'-deoxyguanosine in physiological bicarbonate buffer yields products consistent with the reactive oxygen species carbonate radical anion not the hydroxyl radical. Chemical communications (Cambridge, England). Vol. 56, 9779-9782. Published, 04/01/2021.
• Fleming AM & Zhu J (2021). Cruciform DNA Sequences in Gene Promoters Can Impact Transcription upon Oxidative Modification of 2'-Deoxyguanosine. Biochemistry. Vol. 59, 2616-2626. Published, 03/01/2021.
• Fleming AM (2021). Interplay of Guanine Oxidation and G-Quadruplex Folding in Gene Promoters. Journal of the American Chemical Society. Vol. 142, 1115-1136. Published, 01/01/2021.
• Fleming AM & Zhou J (2020). A Role for the Fifth G-Track in G-Quadruplex Forming Oncogene Promoter Sequences during Oxidative Stress: Do These "Spare Tires" Have an Evolved Function?. ACS central science. Vol. 1, 226-233. Published, 09/01/2020.
• Fleming AM (2020). Colocalization of m6A and G-Quadruplex-Forming Sequences in Viral RNA (HIV, Zika, Hepatitis B, and SV40) Suggests Topological Control of Adenosine N 6-Methylation. ACS central science. Vol. 5, 218-228. Published, 09/01/2020.
• Fleming AM, Alenko A & Kitt JP (2020). Structural Elucidation of Bisulfite Adducts to Pseudouridine That Result in Deletion Signatures during Reverse Transcription of RNA. Journal of the American Chemical Society. Vol. 141, 16450-16460. Published, 09/01/2020.
• Fleming AM & Zhu J (2020). Human NEIL3 Gene Expression Regulated by Epigenetic-Like Oxidative DNA Modification. Journal of the American Chemical Society. Vol. 141, 11036-11049. Published, 09/01/2020.
• Rogers RA (2020). Rapid Screen of Potential i-Motif Forming Sequences in DNA Repair Gene Promoters. ACS omega. Vol. 3, 9630-9635. Published, 09/01/2020.
• Oh J, Fleming AM & Xu J (2020). RNA polymerase II stalls on oxidative DNA damage via a torsion-latch mechanism involving lone pair-π and CH-π interactions. Proceedings of the National Academy of Sciences of the United States of America. Vol. 117, 9338-9348. Published, 08/01/2020.
• Mishra S, Poonia VS & Fontanesi C (2020). Effect of Oxidative Damage on Charge and Spin Transport in DNA. Journal of the American Chemical Society. Vol. 141, 123-126. Published, 06/01/2020.
• Wu J & Sturla SJ (2020). Impact of DNA Oxidation on Toxicology: From Quantification to Genomics. Chemical research in toxicology. Vol. 32, 345-347. Published, 02/01/2020.
• Fleming AM & Zhu J (2020). Oxidative Modification of Guanine in a Potential Z-DNA-Forming Sequence of a Gene Promoter Impacts Gene Expression. Chemical research in toxicology. Vol. 32, 899-909. Published, 02/01/2020.
• Redstone SCJ (2020). Oxidative Modification of the Potential G-Quadruplex Sequence in the PCNA Gene Promoter Can Turn on Transcription. Chemical research in toxicology. Vol. 32, 437-446. Published, 02/01/2020.
• Fleming AM & Burrows CJ (2020). Interplay of Guanine Oxidation and G-Quadruplex Folding in Gene Promoters. Journal of the American Chemical Society. Vol. 142, 1115-1136. Published, 01/01/2020.
• Fleming AM, Zhu J, Howpay Manage SA & Burrows CJ (2019). Human NEIL3 Gene Expression Regulated by Epigenetic-Like Oxidative DNA Modification. Journal of the American Chemical Society. Vol. 141, 11036-11049. Published, 12/01/2019.
• Fleming AM, Nguyen NLB & Burrows CJ (2019). Colocalization of m6A and G-Quadruplex-Forming Sequences in Viral RNA (HIV, Zika, Hepatitis B, and SV40) Suggests Topological Control of Adenosine N6-Methylation. ACS central science. Vol. 5, 218-228. Published, 12/01/2019.
• Johnson RP & Fleming AM (2019). Effect of an Electrolyte Cation on Detecting DNA Damage with the Latch Constriction of α-Hemolysin. The journal of physical chemistry letters. Vol. 5, 3781-3786. Published, 11/01/2019.
• Fleming AM & Alshykhly O (2019). Computational studies of electronic circular dichroism spectra predict absolute configuration assignments for the guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin. Tetrahedron letters. Vol. 56, 3191-3196. Published, 11/01/2019.
• Fleming AM & Zhu J (2019). Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress. Nucleic acids research. Vol. 47, 5049-5060. Published, 11/01/2019.
• Ding Y (2019). α-Hemolysin nanopore studies reveal strong interactions between biogenic polyamines and DNA hairpins. Mikrochimica acta. Vol. 183, 973-979. Published, 11/01/2019.
• Fleming AM, Alenko A, Kitt JP, Orendt AM, Flynn PF, Harris JM & Burrows CJ (2019). Structural Elucidation of Bisulfite Adducts to Pseudouridine That Result in Deletion Signatures during Reverse Transcription of RNA. Journal of the American Chemical Society. Vol. 141, 16450-16460. Published, 11/01/2019.
• Fleming AM, Zhu J, Ding Y & Burrows CJ (2019). Location dependence of the transcriptional response of a potential G-quadruplex in gene promoters under oxidative stress. Nucleic acids research. Vol. 47, 5049-5060. Published, 11/01/2019.
• Mishra S, Poonia VS, Fontanesi C, Naaman R, Fleming AM & Burrows CJ (2019). Effect of Oxidative Damage on Charge and Spin Transport in DNA. Journal of the American Chemical Society. Vol. 141, 123-126. Published, 11/01/2019.
• An N & Fleming AM (2019). Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine. Methods in molecular biology (Clifton, N.J.). Vol. 1973, 15-25. Published, 09/01/2019.
• Tan CS & Fleming AM (2019). γ-Hemolysin Nanopore Is Sensitive to Guanine-to-Inosine Substitutions in Double-Stranded DNA at the Single-Molecule Level. Journal of the American Chemical Society. Vol. 140, 14224-14234. Published, 09/01/2019.
• Anderson CE, Buser JR, Fleming AM & Strauch EM (2019). An integrated device for the rapid and sensitive detection of the influenza hemagglutinin. Lab on a chip. Vol. 19, 885-896. Published, 09/01/2019.
• Anderson CE, Buser JR, Fleming AM, Strauch EM, Ladd PD, Englund J, Baker D & Yager P (2019). An integrated device for the rapid and sensitive detection of the influenza hemagglutinin. Lab on a chip. Vol. 19, 885-896. Published, 09/01/2019.
• An N, Fleming AM, Rosecrans NC, Liao Y & Burrows CJ (2019). Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2'-Deoxyguanosine and 2'-Deoxycytidine. Methods in molecular biology (Clifton, N.J.). Vol. 1973, 15-25. Published, 09/01/2019.
• Vinyard WA & Fleming AM (2019). Characterization of G-Quadruplexes in Chlamydomonas reinhardtii and the Effects of Polyamine and Magnesium Cations on Structure and Stability. Biochemistry. Vol. 57, 6551-6561. Published, 07/01/2019.
• Rogers RA (2019). Unusual Isothermal Hysteresis in DNA i-Motif pH Transitions: A Study of the RAD17 Promoter Sequence. Biophysical journal. Vol. 114, 1804-1815. Published, 06/01/2019.
• Khoddami V, Yerra A & Mosbruger TL (2019). Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proceedings of the National Academy of Sciences of the United States of America. Vol. 116, 6784-6789. Published, 05/01/2019.
• Khoddami V, Yerra A, Mosbruger TL, Fleming AM, Burrows CJ & Cairns BR (2019). Transcriptome-wide profiling of multiple RNA modifications simultaneously at single-base resolution. Proceedings of the National Academy of Sciences of the United States of America. Vol. 116, 6784-6789. Published, 05/01/2019.
• Zhu J (2019). The RAD17 Promoter Sequence Contains a Potential Tail-Dependent G-Quadruplex That Downregulates Gene Expression upon Oxidative Modification. ACS chemical biology. Vol. 13, 2577-2584. Published, 04/01/2019.
• Redstone SCJ, Fleming AM & Burrows CJ (2019). Oxidative Modification of the Potential G-Quadruplex Sequence in the PCNA Gene Promoter Can Turn on Transcription. Chemical research in toxicology. Vol. 32, 437-446. Published, 02/28/2019.
• Fleming AM & Stewart KM (2019). Unraveling the 4n - 1 rule for DNA i-motif stability: base pairs vs. loop lengths. Organic & biomolecular chemistry. Vol. 16, 4537-4546. Published, 02/01/2019.
• Fleming AM, Zhu J, Ding Y, Esders S & Burrows CJ (2019). Oxidative Modification of Guanine in a Potential Z-DNA-Forming Sequence of a Gene Promoter Impacts Gene Expression. Chemical research in toxicology. Vol. 32, 899-909. Published, 02/01/2019.
• Wu J, Sturla SJ, Burrows CJ & Fleming AM (2019). Impact of DNA Oxidation on Toxicology: From Quantification to Genomics. Chemical research in toxicology. Vol. 32, 345-347. Published, 02/01/2019.
• Johnson RP & Fleming AM (2018). Dynamics of a DNA Mismatch Site Held in Confinement Discriminate Epigenetic Modifications of Cytosine. Journal of the American Chemical Society. Vol. 139, 2750-2756. Published, 11/01/2018.
• Ding Y (2018). Sequencing the Mouse Genome for the Oxidatively Modified Base 8-Oxo-7,8-dihydroguanine by OG-Seq. Journal of the American Chemical Society. Vol. 139, 2569-2572. Published, 11/01/2018.
• Omaga CA (2018). The Fifth Domain in the G-Quadruplex-Forming Sequence of the Human NEIL3 Promoter Locks DNA Folding in Response to Oxidative Damage. Biochemistry. Vol. 57, 2958-2970. Published, 09/01/2018.
• Johnson RP & Perera RT (2018). Energetics of base flipping at a DNA mismatch site confined at the latch constriction of α-hemolysin. Faraday discussions. Vol. 193, 471-485. Published, 09/01/2018.
• Ren H & Cheyne CG (2018). Single-Molecule Titration in a Protein Nanoreactor Reveals the Protonation/Deprotonation Mechanism of a C:C Mismatch in DNA. Journal of the American Chemical Society. Vol. 140, 5153-5160. Published, 07/01/2018.
• Zeng T, Fleming AM & Ding Y (2018). Nanopore Analysis of the 5-Guanidinohydantoin to Iminoallantoin Isomerization in Duplex DNA. The Journal of organic chemistry. Vol. 83, 3973-3978. Published, 07/01/2018.
• Tan CS & Riedl J (2018). Kinetics of T3-DNA Ligase-Catalyzed Phosphodiester Bond Formation Measured Using the α-Hemolysin Nanopore. ACS nano. Vol. 10, 11127-11135. Published, 07/01/2018.
• Fleming AM, Zhu J & Ding Y (2018). Human DNA Repair Genes Possess Potential G-Quadruplex Sequences in Their Promoters and 5'-Untranslated Regions. Biochemistry. Vol. 57, 991-1002. Published, 06/01/2018.
• Zhang Y, Li XB, Fleming AM & Dood J (2018). UV-Induced Proton-Coupled Electron Transfer in Cyclic DNA Miniduplexes. Journal of the American Chemical Society. Vol. 138, 7395-401. Published, 05/01/2018.
• Fleming AM, Ding Y, Rogers RA & Zhu J (2018). 4n-1 Is a "Sweet Spot" in DNA i-Motif Folding of 2'-Deoxycytidine Homopolymers. Journal of the American Chemical Society. Vol. 139, 4682-4689. Published, 05/01/2018.
• Fleming AM (2018). Oxidative DNA damage is epigenetic by regulating gene transcription via base excision repair. Proceedings of the National Academy of Sciences of the United States of America. Vol. 114, 2604-2609. Published, 04/01/2018.
• Fleming AM (2018). 8-Oxo-7,8-dihydro-2'-deoxyguanosine and abasic site tandem lesions are oxidation prone yielding hydantoin products that strongly destabilize duplex DNA. Organic & biomolecular chemistry. Vol. 15, 8341-8353. Published, 04/01/2018.
• Fleming AM (2018). Sequencing DNA for the Oxidatively Modified Base 8-Oxo-7,8-Dihydroguanine. Methods in enzymology. Vol. 591, 187-210. Published, 04/01/2018.
• Fleming AM (2018). Formation and processing of DNA damage substrates for the hNEIL enzymes. Free radical biology & medicine. Vol. 107, 35-52. Published, 02/01/2018.
• Fleming AM & Ding Y (2018). Zika Virus Genomic RNA Possesses Conserved G-Quadruplexes Characteristic of the Flaviviridae Family. ACS infectious diseases. Vol. 2, 674-681. Published, 01/01/2018.
• Fleming AM (2017). 8-Oxo-7,8-dihydroguanine, friend and foe: Epigenetic-like regulator versus initiator of mutagenesis. DNA repair. Vol. 56, 75-83. Published, 11/01/2017.
• Alenko A (2017). Reverse Transcription Past Products of Guanine Oxidation in RNA Leads to Insertion of A and C opposite 8-Oxo-7,8-dihydroguanine and A and G opposite 5-Guanidinohydantoin and Spiroiminodihydantoin Diastereomers. Biochemistry. Vol. 56, 5053-5064. Published, 10/01/2017.
• Fleming AM & Zhu J (2017). 8-Oxo-7,8-dihydroguanine in the Context of a Gene Promoter G-Quadruplex Is an On-Off Switch for Transcription. ACS chemical biology. Vol. 12, 2417-2426. Published, 10/01/2017.
• Zeng T & Fleming AM (2017). Interrogation of Base Pairing of the Spiroiminodihydantoin Diastereomers Using the α-Hemolysin Latch. Biochemistry. Vol. 56, 1596-1603. Published, 05/01/2017.
• Perera RT, Fleming AM & Peterson AM (2016). Unzipping of A-Form DNA-RNA, A-Form DNA-PNA, and B-Form DNA-DNA in the α-Hemolysin Nanopore. Biophysical journal. Vol. 110, 306-314. Published, 10/01/2016.
• Riedl J (2016). Sequencing of DNA Lesions Facilitated by Site-Specific Excision via Base Excision Repair DNA Glycosylases Yielding Ligatable Gaps. Journal of the American Chemical Society. Vol. 138, 491-4. Published, 10/01/2016.
• Johnson RP & Fleming AM (2016). Base Flipping within the α-Hemolysin Latch Allows Single-Molecule Identification of Mismatches in DNA. Journal of the American Chemical Society. Vol. 138, 594-603. Published, 10/01/2016.
• An N (2016). Human Telomere G-Quadruplexes with Five Repeats Accommodate 8-Oxo-7,8-dihydroguanine by Looping out the DNA Damage. ACS chemical biology. Vol. 11, 500-7. Published, 10/01/2016.
• Ding Y & Fleming AM (2016). Differentiation of G:C vs A:T and G:C vs G:mC Base Pairs in the Latch Zone of α-Hemolysin. ACS nano. Vol. 9, 11325-32. Published, 09/01/2016.
• Alshykhly OR (2016). Guanine oxidation product 5-carboxamido-5-formamido-2-iminohydantoin induces mutations when bypassed by DNA polymerases and is a substrate for base excision repair. Chemical research in toxicology. Vol. 28, 1861-71. Published, 08/01/2016.
• Zhu J & Fleming AM (2016). pH-Dependent Equilibrium between 5-Guanidinohydantoin and Iminoallantoin Affects Nucleotide Insertion Opposite the DNA Lesion. The Journal of organic chemistry. Vol. 81, 351-9. Published, 06/01/2016.
• Fleming AM & Alshykhly O (2016). Rates of chemical cleavage of DNA and RNA oligomers containing guanine oxidation products. Chemical research in toxicology. Vol. 28, 1292-300. Published, 05/01/2016.
• Ding Y & Fleming AM (2016). Unfolding Kinetics of the Human Telomere i-Motif Under a 10 pN Force Imposed by the α-Hemolysin Nanopore Identify Transient Folded-State Lifetimes at Physiological pH. Journal of the American Chemical Society. Vol. 137, 9053-60. Published, 05/01/2016.
• Alshykhly OR (2016). 5-Carboxamido-5-formamido-2-iminohydantoin, in Addition to 8-oxo-7,8-Dihydroguanine, Is the Major Product of the Iron-Fenton or X-ray Radiation-Induced Oxidation of Guanine under Aerobic Reducing Conditions in Nucleoside and DNA Contexts. The Journal of organic chemistry. Vol. 80, 6996-7007. Published, 02/01/2016.
• An N & Fleming AM (2016). Nanopore detection of 8-oxoguanine in the human telomere repeat sequence. ACS nano. Vol. 9, 4296-307. Published, 02/01/2016.
• Perera RT & Fleming AM (2015). Detection of benzo[a]pyrene-guanine adducts in single-stranded DNA using the α-hemolysin nanopore. Nanotechnology. Vol. 26, 074002. Published, 11/01/2015.
• Zhou J & Fleming AM (2015). The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures. (pp. 7171). Vol. 43. Nucleic acids research. Published, 10/01/2015.
• Fleming AM & Armentrout EI (2015). Spirodi(iminohydantoin) products from oxidation of 2'-deoxyguanosine in the presence of NH4Cl in nucleoside and oligodeoxynucleotide contexts. The Journal of organic chemistry. Vol. 80, 711-21. Published, 08/01/2015.
• Ding Y & Fleming AM (2015). Internal vs fishhook hairpin DNA: unzipping locations and mechanisms in the α-hemolysin nanopore. The journal of physical chemistry. B. Vol. 118, 12873-82. Published, 07/01/2015.
• Zhou J & Fleming AM (2015). The NEIL glycosylases remove oxidized guanine lesions from telomeric and promoter quadruplex DNA structures. Nucleic acids research. Vol. 43, 4039-54. Published, 07/01/2015.
• An N & Fleming AM (2015). Single-molecule investigation of G-quadruplex folds of the human telomere sequence in a protein nanocavity. Proceedings of the National Academy of Sciences of the United States of America. Vol. 111, 14325-31. Published, 04/01/2015.
• Johnson RP & Fleming AM (2015). Temperature and electrolyte optimization of the α-hemolysin latch sensing zone for detection of base modification in double-stranded DNA. Biophysical journal. Vol. 107, 924-31. Published, 04/01/2015.
• Wolna AH (2015). Single-molecule analysis of thymine dimer-containing G-quadruplexes formed from the human telomere sequence. Biochemistry. Vol. 53, 7484-93. Published, 02/01/2015.
• Fleming AM (2014). G-quadruplex folds of the human telomere sequence alter the site reactivity and reaction pathway of guanine oxidation compared to duplex DNA. Chemical research in toxicology. Vol. 26, 593-607. Published, 09/01/2014.
• Jin Q, Fleming AM & Johnson RP (2014). Base-excision repair activity of uracil-DNA glycosylase monitored using the latch zone of α-hemolysin. Journal of the American Chemical Society. Vol. 135, 19347-53. Published, 09/01/2014.
• Krokeide SZ, Laerdahl JK, Salah M & Luna L (2014). Human NEIL3 is mainly a monofunctional DNA glycosylase removing spiroimindiohydantoin and guanidinohydantoin. DNA repair. Vol. 12, 1159-64. Published, 07/01/2014.
• Fleming AM, Orendt AM & He Y (2014). Reconciliation of chemical, enzymatic, spectroscopic and computational data to assign the absolute configuration of the DNA base lesion spiroiminodihydantoin. Journal of the American Chemical Society. Vol. 135, 18191-204. Published, 07/01/2014.
• Eckenroth BE & Fleming AM (2014). Crystal structure of DNA polymerase β with DNA containing the base lesion spiroiminodihydantoin in a templating position. Biochemistry. Vol. 53, 2075-7. Published, 06/01/2014.
• McKibbin PL, Fleming AM & Towheed MA (2014). Repair of hydantoin lesions and their amine adducts in DNA by base and nucleotide excision repair. Journal of the American Chemical Society. Vol. 135, 13851-61. Published, 04/01/2014.
• An N (2014). Interactions of the human telomere sequence with the nanocavity of the α-hemolysin ion channel reveal structure-dependent electrical signatures for hybrid folds. Journal of the American Chemical Society. Vol. 135, 8562-70. Published, 01/01/2014.
• Jin Q & Fleming AM (2014). Structural destabilization of DNA duplexes containing single-base lesions investigated by nanopore measurements. Biochemistry. Vol. 52, 7870-7. Published, 01/01/2014.
• Zhou J & Liu M (2013). Neil3 and NEIL1 DNA glycosylases remove oxidative damages from quadruplex DNA and exhibit preferences for lesions in the telomeric sequence context. The Journal of biological chemistry. Vol. 288, 27263-27272. Published, 11/01/2013.
• Fleming AM & Muller JG (2013). Structural context effects in the oxidation of 8-oxo-7,8-dihydro-2'-deoxyguanosine to hydantoin products: electrostatics, base stacking, and base pairing. Journal of the American Chemical Society. Vol. 134, 15091-102. Published, 02/01/2013.
• Khoo NK, Cantu-Medellin N, Devlin JE, St Croix CM & Watkins SC (2012). Obesity-induced tissue free radical generation: an in vivo immuno-spin trapping study. Free radical biology & medicine. Vol. 52, 2312-9. Published, 10/01/2012.
• An N & Fleming AM (2012). Crown ether-electrolyte interactions permit nanopore detection of individual DNA abasic sites in single molecules. Proceedings of the National Academy of Sciences of the United States of America. Vol. 109, 11504-9. Published, 10/01/2012.
• Jin Q & Fleming AM (2012). Unzipping kinetics of duplex DNA containing oxidized lesions in an α-hemolysin nanopore. Journal of the American Chemical Society. Vol. 134, 11006-11. Published, 10/01/2012.
• Schibel AE, Fleming AM, Jin Q & An N (2012). Sequence-specific single-molecule analysis of 8-oxo-7,8-dihydroguanine lesions in DNA based on unzipping kinetics of complementary probes in ion channel recordings. Journal of the American Chemical Society. Vol. 133, 14778-84. Published, 01/01/2012.
• Fleming AM & Kannan A (2012). Copper/H2O2-mediated oxidation of 2'-deoxyguanosine in the presence of 2-naphthol leads to the formation of two distinct isomeric adducts. The Journal of organic chemistry. Vol. 76, 7953-63. Published, 01/01/2012.
• Sejersted Y, Hildrestrand GA, Kunke D, Rolseth V, Krokeide SZ & Neurauter CG (2012). Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia. Proceedings of the National Academy of Sciences of the United States of America. Vol. 108, 18802-7. Published, 01/01/2012.
• Fleming AM & Muller JG (2011). Characterization of 2'-deoxyguanosine oxidation products observed in the Fenton-like system Cu(II)/H2O2/reductant in nucleoside and oligodeoxynucleotide contexts. Organic & biomolecular chemistry. Vol. 9, 3338-48. Published, 08/01/2011.
• Schibel AE, An N & Jin Q (2011). Nanopore detection of 8-oxo-7,8-dihydro-2'-deoxyguanosine in immobilized single-stranded DNA via adduct formation to the DNA damage site. Journal of the American Chemical Society. Vol. 132, 17992-5. Published, 04/01/2011.
• Burrows CJ (2009). Finding needles in DNA stacks. (pp. 16010-1). Vol. 106. Proceedings of the National Academy of Sciences of the United States of America. Published, 11/01/2009.
• Markus TZ, Daube SS & Naaman R (2009). Electronic structure of DNA--unique properties of 8-oxoguanosine. Journal of the American Chemical Society. Vol. 131, 89-95. Published, 03/01/2009.
• Xu X & Fleming AM (2008). Formation of tricyclic [4.3.3.0] adducts between 8-oxoguanosine and tyrosine under conditions of oxidative DNA-protein cross-linking. Journal of the American Chemical Society. Vol. 130, 10080-1. Published, 09/01/2008.

Presentations

• DNA Base pairs beyond Watson and Crick: G-Quadruplexes and i-Motifs. Adams State University. Invited Talk/Keynote, Presented, 11/22/2019.
• Base modifications in DNA non-canonical structures regulate transcription. American Chemical Society National Meeting, San Diego, CA. Invited Talk/Keynote, Presented, 08/21/2019.