THUNDER JALILI, PhD portrait
  • Director of Graduate Studies, Nutrition & Integrative Physiology
  • Director of Undergraduate Studies, Nutrition & Integrative Physiology
  • Adjunct Associate Professor, Health and Kinesiology
  • Professor, Nutrition & Integrative Physiology

Research Statement

Cardiovascular disease (CVD) is the most prevalent public health problem facing the United States and the rest of the Western world. Many researchers believe that diet is critical for both prevention and treatment of CVD. To this end my research is focused on understanding how cardiovascular function and metabolism can be regulated by consumption of macronutrients, as well as supplementation with magnesium, and dietary phytochemicals. The goals of my research are to determine efficacy of supplements and diet therapy, and answer questions regarding optimum dosage and mechanisms of action.

Research Keywords

  • Phytochemicals and bioactive components
  • Nutrition
  • High blood pressure
  • Cell signaling
  • Cardiac hypertrophy

Presentations

  • Metabolic and Vascular Effects of Low Dietary Magnesium During Healthy and Diabetic Conditions. Invited Talk/Keynote, Presented, 01/27/2017.
  • Lipotoxicity-Evoked Reductions in Nitric Oxide Bioavailability and Exaggerated Oxidant Stress Are Blunted By Blueberry Metabolites in Human Vascular Endothelial Cells. D. Bharat, N. Begaye, R. Ramos, M. Ferreira, Y. Li, B. Cutler, L.P. Bharath, J.D. Symons, T. Jalili, A.B.P Velayutham. THE FASEB Journal, in press (2016). Poster, Presented, 04/2016.
  • Seminars in Metabolism, University of Utah Health Sciences, Salt Lake City, UT, March 24, 2016. Role of magnesium in metabolism and vascular health. Presentation, Submitted, 03/24/2016.
  • Park City Medical Center, Live well seminar. January 13, 2016. A re-evaluation of fat and sugar as factors for mortality from coronary heart disease. Invited Talk/Keynote, Presented, 01/13/2016.
  • Dietary Fat and Cardiovascular Health; a shifting perspective over time. Invited Talk/Keynote, Accepted, 11/05/2015.
  • Metabolites of Blueberry Anthocyanins Suppress Lipotoxicity Induced Endothelial Inflammation. R. Cavalcanti, N. Begaye, M. Costa, L.P. Bharath, J.D. Symons, T. Jalili, N.S. Rajasekaran, Z. Jia, P.V.A. Babu. FASEB Journal, 29:118.6 (2015). Poster, Presented, 04/2015.
  • Gamma-Carboxyethyl Hydroxychroman Preserves Nitric Oxide Bioavailability by Attenuating Oxidative Stress and Inflammation in Endothelial Cells Treated with High Glucose. Youyou Li, Leena Bharath, Ying Quan, Eunice Mah, Yi Guo, Makenzie Hawkins, Richard Bruno, PVA Babu, Thunder Jalili, and J David Symons. FASEB Journal, Apr 2015; 29: 758.1. Presentation, Presented, 04/2015.
  • Flavonoids and Vascular Health: From Cells to Humans . Invited Talk/Keynote, Presented, 03/27/2015.
  • University of Utah Seminars in Metabolism, Division of Endocrinology, Metabolism, and Diabetes, Salt Lake City, UT, October 23, 2014. Phytochemicals and vascular health; from cells to humans. Invited Talk/Keynote, Presented, 10/2014.
  • Efficacy of a polyphenolic supplement to reduce blood pressure in patients with Metabolic syndrome. Melalueca National Convention, Salt Lake City, UT. Invited Talk/Keynote, Presented, 05/2013.
  • University of Utah Seminars in Metabolism, Division of Endocrinology, Metabolism, and Diabetes, Salt Lake City, UT. Botanical agents to lower blood pressure; an investigation of polyphenol supplements for hypertension and metabolic syndrome. Invited Talk/Keynote, Presented, 04/2013.
  • Vitamin C Status Is Inversely Related To Quercetin Bioavailability In Young Adults. Guo Y, Mah E, Jalili T, Bruno RS. Experimental Biology 2013. Presentation, Presented, 04/2013.
  • University of Utah Division of Cardiology Grand Rounds. “Update on the role of diet & supplements on CVD risk factors.” . Invited Talk/Keynote, Presented, 05/2012.
  • Variability of Oxidant status in women of childbearing potential. Artz T, Jalili T, Michael Goodman M, Murtaugh MA. Experimental Biology 2012. FASEB J. Poster, Presented, 04/2012.
  • Quercetin Bioavailability And Biotransformation Are Inversely Related To Vitamin C Status In College-Aged Adults. Guo Y, Mah E, Jalili T, Bruno RS. Experimental Biology 2012. FASEB J. Poster, Presented, 04/2012.
  • A mixture of grape seed & skin extract, green tea extract, resveratrol, and quercetin reduces blood pressure in hypertensive subjects with metabolic syndrome. Jalili T, Beisinger S, Quadros A, Rabovsky A. Experimental Biology 2012. FASEB J. Presentation, Presented, 04/2012.
  • A carbohydrate restricted – high fat diet reduces blood pressure in spontaneously hypertensive rats without causing insulin resistance. Jalili T, Bosse J, Dolinsky V, Sloan C, Zhang QJ, Abel ED, Symons JD. Experimental Biology 2012. Presentation, Presented, 04/2012.
  • Li Y, Huang Y, Nunthakungwan O, Boudina S, Wende AR, Abel ED, Jalili T. Discordance between cardiac hypertrophy and oxidative stress in cardiac specific GLUT4 deleted mice treated with antioxidants. Society of Heat and Vascular Metabolism (SHVM), Brussels, Belgium, June 18-21, 2011. Poster, Presented, 06/2011.
  • Bosse J, Sloan C, Abel ED, Symons, JD, Jalili T. A high fat – low carbohydrate diet reduces blood pressure in spontaneously hypertensive rats with out altering cardiac hypertrophy or causing insulin resistance. Society of Heat and Vascular Metabolism (SHVM), Kananaskis, Alberta, Canda. August 22-25, 2010. Poster, Presented, 08/2010.
  • Larson A, Bruno R, Guo Y, Gale D, Tanner J, Jalili T, Symons JD. A single dose of quercetin lowers blood pressure in hypertensive, but not normotensive males. Experimental Biology 2010. FASEB J April 6, 2010 24:230.6. Poster, Presented, 04/2010.
  • Mihalopoulos, J., D. Bennett , T. Jalili, Daniel P. Williams, J. McDaniel, R.S. Richardson, E.W. Askew. Effects of Bison Compared to Beef Consumption on Selected Inflammation Biomarkers. Experimental Biology 2009, April 18-22, 2009. FASEB J, Apr 2009; 23: LB481. Poster, Presented, 04/2009.
  • Jalili, T, Soesanto WS, Hu E, Lin H, Symons JD. The mammalian target of rapamycin plays a critical role in the development of cardiac hypertrophy in spontaneously hypertensive rats. American Heart Association Scientific Sessions 2008. Circulation, Oct 2008; 118: S 276. Poster, Presented, 10/2008.
  • Jalili, T, Soesanto WS, Hu E, Lin H, Symons JD. mTOR plays a critical role in the development of cardiac hypertrophy in spontaneously hypertensive rats. Keystone Symposia: Metabolism and Cardiovascular Risk, September 24-28, 2008, Breckenridge, CO. Poster, Presented, 09/2008.
  • Jalili, T, Nunthakungwan O, Li, Y, Jin HF, Hu E, Wende AR, Abel ED. Mitochondrial oxidative stress does not contribute to cardiac hypertrophy in mice with cardiac specific GLUT4 deletion. Experimental Biology 2008, April 5-9, 2008. FASEB J, Mar 2008; 22: 614.21. Poster, Presented, 04/2008.
  • Zaha VG, Hungerford PR, Li Y, Nunthakungwan O, Safaee M, Jalili T, Abel ED. Hypertrophy in GLUT4 Deficient Hearts Results From Increased Sensitivity of mTOR Signaling. American Heart Association Scientific Session 2006. Circulation vol. 114, No. 18, 2006. Poster, Presented, 11/2006.
  • Jalili T, Edwards R, Lyon T, Symons JD. Quercetin Reduces Blood Pressure in Hypertensive Subjects. American Heart Association Scientific Session 2006. Circulation vol. 114, No. 18, 2006. Presentation, Presented, 11/2006.
  • Jalili, T, Lefler S, Symons JD, Carlstrom J. Activation of ERK1/2, Akt and S6 kinase, but not PKC, prior to cardiac hypertrophy in Spontaneously Hypertensive Rats. Experimental Biology 2006, April 1-5, 2006. FASEB Journal Abstracts 20(5) Part II: Abstract 415.10, March 7, 2006. Poster, Presented, 04/2006.
  • Jalili, T, Guzman C, Jin H, Abel ED. Activation Of PKC Isoforms In Hypertrophied GLUT4 Deficient Hearts. Experimental Biology 2006, April 1-5, 2006. FASEB Journal Abstracts 20(4) Part I: Abstract 468.12, March 6, 2006. Poster, Presented, 04/2006.
  • Abe JI, Jalili T, Itoh S, Ding B, Bains CP, Wang N, Takeishi Y, King GL, Walsh RA, Yan C. Role of p90 Ribosomal S6 Kinase (p90RSK) in cardiac Troponin I phosphorylation and possible involvement in cardiac dysfunction after ischemia/reperfusion. American Heart Association: Targeting Heart Failure: New Science, New Tools, New Strategies; July 24-27, 2005. Poster, Presented, 07/2005.
  • Jalili T, Carlstrom JA, Wu TC, Litwin SE, Symons JD. Quercetin consumption does not prevent hypertension and cardiovascular complications in spontaneously hypertensive rats (SHR). Experimental Biology 2005, April 2-6, 2005. FASEB Journal Abstracts 19(4) Part I: Abstract 282.11, March, 2005. Poster, Presented, 04/2005.
  • Symons JD, Carlstrom J, Dong L, Jalili T. Quercetin limits dysfunction of mesenteric arteries from spontaneously hypertensive rats. Experimental Biology 2004, April 17-21, 2004. FASEB Journal Abstracts 18(4) Part I: Abstract 362.12, March 24, 2004. Poster, Presented, 04/2004.
  • Jalili T, Dong L, Mattson J. Activation Of ERK 1/2 And PKC ε In Right Ventricular Hypertrophy Secondary To Emphysema In Male Syrian Golden Hamsters. Experimental Biology 2004, April 17-21, 2004. FASEB Journal Abstracts 18(5) Part II: Abstract 734.3, March 24, 2004. Presentation, Presented, 04/2004.
  • Symons JD, Nguyen Q, Williams B, Jalili T. Quercetin limits vascular dysfunction associated with pressure-overload left-ventricular hypertrophy. Experimental Biology 2003, April 11-15, 2003, FASEB Journal Abstracts 17(4) Part I: Abstract 397.5, March 14, 2003. Poster, Presented, 04/2003.
  • Jalili T, Kim S, Manning J, Wildman RE, Kurowska EM, Freeman D. Dietary Quercetin reduces cardiac hypertrophy and decreases cardiac PKC β2 activation in rats. Experimental Biology 2002, April 20-24. FASEB Journal Abstracts 16(4) Part I: Abstract 488.5, March 20, 2002. Poster, Presented, 04/2002.
  • Manning J, Kim S, Jalili T. Dietary Fat From Coconut Oil Results in Mild Cardiac Hypertrophy and PKC Activation. Experimental Biology 2001 April 7-11, FASEB Journal Abstracts 15(5) Part II: A996, Abstract 759.14, March 8, 2001. Poster, Presented, 04/2001.
  • Takeishi, Jalili T, Kirkpatrick DL, Wagoner LE, Abraham WT, Walsh RA. Differential alterations in calcium cycling and Gαq signaling proteins after left ventricular assist device support in failing human hearts. 72st Scientific Sessions of the American Heart Association, November 7-10, 1999. Poster, Presented, 11/1999.
  • Takeishi Y, Jalili T, Kirkpatrick DL, Wagoner LE, Abraham WT, Walsh RA. Differential alterations in calcium cycling and Gαq signaling proteins after left ventricular assist device support in failing human hearts. 3rd Annual Meeting of the Heart Failure Society of America, September 22-25, 1999. Poster, Presented, 09/1999.
  • Jalili T, Song G, Paul K, Takeishi Y, Ball NA, Walsh RA. Phospholipase c activation and protein kinase c activity are enhanced during pressure overload hypertrophy and congestive heart failure in the adult guinea pig. 71st Scientific Sessions of the American Heart Association, November 8-11, 1998. Poster, Presented, 11/1998.
  • Takeishi Y, Jalili T, Ball NA, Walsh RA. Oxidative stress produces differential activation of protein kinase c isoforms in adult guinea pig hearts. 71st Scientific Sessions of the American Heart Association. November 8-11, 1998. Poster, Presented, 11/1998.
  • Jalili T, Wildman REC, Medeiros DM, Shiry L, Ireton J. Levels of nuclear encoded peptides of cardiac cytochrome c oxidase are unchanged between rats fed copper restricted low and high fat diets for an 18 day period. Experimental Biology '97, FASEB Journal Abstracts, 11(3) (abstract 1055), 1997. Poster, Presented, 04/1997.
  • Jalili T, Medeiros DM, Wildman REC. Cardiomyopathic indices of copper restricted rats are exacerbated by high dietary saturated fat. Experimental Biology '95, FASEB Journal Abstracts, 9 (4):724 (abstract 4198), 1995. Presentation, Presented, 04/1995.

Grants, Contracts & Research Gifts

  • DIETARY ANTHOCYANINS FOR THE PREVENTION OF VASCULAR DISEASE IN DIABETES. PI: A. Velayutham. 07/01/2013 - 06/30/2015. Total project budget to date: $5,000.00
  • CARDIAC HYPERTROPHY DUE TO OXIDATIVE STRESS INSULIN (R15HL085226). PI: Jalili, Thunder. National Institutes of Health, 08/01/2006 - 07/31/2009. Total project budget to date: $224,250.00
  • Exercise-training improves endothelial cell autophagy in older adults. PI: Symons. UU Seed Grant, 11/15/2017 - 11/14/2018. Total project budget to date: $20,000.00
  • Characterizing the phenotype of young and old mice with disrupted vascular autophagy. PI: Symons. NIH/NIA , 01/01/2017 - 12/31/2018. Total project budget to date: $50,000.00
  • The role of ceramide in contributing to vascular dysfunction in diet-induced obesity. PI: Symons. National Institutes of Health, 08/2012 - 07/2015. Total project budget to date: $300,000.00
  • Mechanisms whereby endogenous ceramide impairs eNOS signaling and arterial function. PI: Symons. American Diabetes Association Research Grant, 01/2012 - 12/2014. Total project budget to date: $300,000.00
  • Determination of reactive oxygen / nitrogen species in cell culture models of oxidant stress using electron paramagnetic spectroscopy (EPR). PI: Symons. UU Interdisciplinary Research Grant , 01/2010 - 12/2010. Total project budget to date: $0.00
  • Role of ceramide in obesity-related vascular dysfunction. PI: Symons. American Diabetes Association Research Grant, 07/2008 - 11/2011. Total project budget to date: $0.00
  • Determining the contribution from ceramide to cardiovascular complications associated with obesity in Sptlcb2+ mice. PI: Symons. UU Research Committee Faculty and Research and Creative Grant , 07/2008 - 06/2010. Total project budget to date: $0.00

Languages

  • English, fluent.
  • Western Farsi, functional.

Publications

  • Priyankar Dey, P & Mah E, Li J, Jalili T, Symons JD, Bruno RS (2019). Improved hepatic γ-tocopherol status limits oxidative and inflammatory stress-mediated liver injury in db/db mice with nonalcoholic steatohepatitis. Journal of Functional Foods. Accepted, 01/01/2019.
  • Anandh Babu, PV & Piccolo B, Symons JD, Mueller JE, Chintapalli, S, Jalili T, Jia Z, Petersen C, Bharat D, Wong K, Wankhade U, Shankar K (2019). Dietary supplementation with strawberry induces marked changes in the composition and functional potential of the gut microbiome in diabetic mice. Journal of Nutritional Biochem. Accepted, 01/01/2019.
  • Bharat, D & Cavalcanti R, Petersen C, Begaye N, Cutler B, Costa M, Ramos R, Ferreira M, Li Y, Bharath LP, Toolson E, Sebahar P, Looper R, Jalili T, Rajasekaran N, Zhenquan J, Symons JD. Anandh Babu PV. (2018). Blueberry metabolites attenuate lipotoxicity-induced endothelial dysfunction. Molecular Nutrition and Food Research. Vol. 62(2). Published, 01/01/2018.
  • Qian Y & Anandh Babu PV, Symons JD, Jalili T (2017). Metabolites of flavonoid compounds preserve indices of endothelial cell nitric oxide bioavailability under glucotoxic conditions. Nutrition and Diabetes. Vol. 11:7(9). Published, 09/01/2017.
  • Li, Y & Bharath LP, Qian Y, Ruan T, Anandh Babu PV, Bruno RS, Symons JD, Jalili T. (2016). 5. Carboxyethyl Hydroxychroman, a metabolite of tocopherol, preserves nitric oxide bioavailability in endothelial cells challenged with high glucose. Exp Biol and Medicine. Vol. 18, 2056-2062. Published, 12/01/2016.
  • The Association Between Plant Protein Intake and All-Cause Mortality in Chronic Kidney Disease. Chen X, Wei G, Jalili T, Metos J, Giri A, Cho M, Greene T, Beddhu S. Am J Kidney Disease, Mar;67(3):423-30. 2016. Published, 03/2016.
  • Biesinger S, Michaels HA, Quadros AS, Qian Y, Rabovsky AB, Badger RS & Jalili T (2016). A combination of isolated phytochemicals and botanical extracts lowers diastolic blood pressure in a randomized controlled trial of hypertensive subjects. European journal of clinical nutrition. Vol. 70, 10-6. Published, 01/01/2016.
  • Kwon, Oh Sung, Tanner, Ruth E, Barrows, Katherine M, Runtsch, Marah, Symons, J. David, Jalili, Thunder, Bikman, Benjamin T., McClain, Donald A., O'Connell, Ryan M & Drummond, Micah J. (2015). MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling and glucose intolerance. American Physiological Society. , ajpendo.00124.2015. Published, 2015.
  • MyD88 regulates physical inactivity-induced skeletal muscle inflammation, ceramide biosynthesis signaling and glucose intolerance. Kwon OS, Tanner R, Barrows K, Runtsch M, Symons JD, Jalili T, BT, McClain D, O'Connell R, and Drummond M. Am J Physiol; Endocrine and Metabolism, 309(1), E11-21, 2015. Published, 07/2015.
  • Agergaard, J., Carlin, M. B., Drummond, M. J., Jalili, T., McClain, D. A. & Tanner, R. E. (2014). Skeletal Muscle Ras-Related GTP Binding B mRNA and Protein Expression Is Increased after Essential Amino Acid Ingestion in Healthy Humans. American Society for Nutrition. Vol. 144(9), 1409-1414. Published, 2014.
  • Regulation of Leucyl-tRNA Synthetase and RagB expression in human skeletal muscle by essential amino acids. Carlin MB, Tanner RE, Agergaard J, Jalili T, McClain D, Drummond MJ. Journal of Nutrition, 144(9):1409-14, 2014. Published, 07/2014.
  • Bruno, Richard S., Chun, Ock K., Jalili, Thunder, Mah, Eunice, Davis, Catherine G., Ferruzzi, Mario G. & Guo, Yi (2013). Dietary fat increases quercetin bioavailability in overweight adults. Wiley-Blackwell. Vol. 57(5), 896-905. Published, 2013.
  • Abel, E. D., Bosse, J. D., Dolinsky, V. W., Jalili, T., Lin, H. Y., Pereira, T. J., Sloan, C., Symons, J. D. & Zhang, Q.-J. (2013). A low-carbohydrate/high-fat diet reduces blood pressure in spontaneously hypertensive rats without deleterious changes in insulin resistance. American Physiological Society. Vol. 304(12), H1733-H1742. Published, 2013.
  • Bosse JD, Lin H, Soesanto W, Sloan C, Zhang QJ, Abel ED, Pereira, T, Dolinsky V, Symons JD, Jalili T. A low carbohydrate – high fat diet reduces blood pressure in spontaneously hypertensive rats without altering cardiac hypertrophy or causing insulin resistance. American Journal of Physiology; Heart and Circulatory Physiology 304:H1733-H1742, 2013. Published, 06/15/2013.
  • Guo Y, Mah E, Davis C, Jalili T, Ferruzzi M, Chun O, Bruno RS. Dietary fat increases quercetin bioavailability in overweight adults. Molecular Nutrition and Food Research. Published, 02/2013.
  • Symons, J. D., Jalili, T. & Larson, A. J. (2012). Therapeutic Potential of Quercetin to Decrease Blood Pressure: Review of Efficacy and Mechanisms. American Society for Nutrition. Vol. 3(1), 39-46. Published, 2012.
  • Nunthakungwan, Orathai, Abel, E. Dale, Boudina, Sihem, Jin, Huifeng, Hu, Eric, Huang, Yujia, Wende, Adam R., Jalili, Thunder & Li, Yan (2012). Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice: Cardiac specific GLUT4 deletion and oxidative stress. Wiley-Blackwell. Vol. 279(4), 599-611. Published, 2012.
  • Jalili, Thunder, Witman, Melissa A.H., Larson, Abigail, Symons, J. David, Ives, Stephen, Guo, Yi, Bruno, Richard S. & Richardson, Russell S. (2012). Acute, quercetin-induced reductions in blood pressure in hypertensive individuals are not secondary to lower plasma angiotensin-converting enzyme activity or endothelin-1: nitric oxide. Elsevier BV. Vol. 32(8), 557-564. Published, 2012.
  • Larson AJ, Witman MAH, Guo Y, Black K, M Hayman M, Richardson RS, Bruno RS, Jalili T, Symons JD. Acute, quercetin-induced reductions in blood pressure in hypertensives are not secondary to lower plasma angiotensin converting enzyme activity or endothelin-1 : nitric oxide. Nutrition Research, 32:557-64, 2012. Published, 08/2012.
  • Larson AJ, Symons JD, Jalili T. Therapeutic potential of Quercetin to reduce blood pressure; review of efficacy and mechanisms. Advances in Nutrition. 3:39-46, 2012. Published, 02/2012.
  • Jalili T, Li Y, Nunthakungwan O, Hu E, Jin H, Boudina S, Wende AR, Abel ED. Cytosolic, not mitochondrial, oxidative stress likely contributes to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice. FEBS Journal, 279:599-611, 2012. Published, 01/2012.
  • Symons, J. David, Jalili, Thunder & Larson, Abigail J. (2010). Quercetin: A Treatment for Hypertension?—A Review of Efficacy and Mechanisms. MDPI AG. Vol. 3(1), 237-250. Published, 2010.
  • Larson AJ, Symons JD, Jalili T. Quercetin: A Treatment for Hypertension?—A Review of Efficacy and Mechanisms. Pharmaceuticals, 3;237-250, 2010. Published, 07/2010.
  • Hu, E., Lin, H.-y., Lefler, S., Sena, S., Jalili, T., Litwin, S. E., Soesanto, W., Symons, J. D. & Abel, E. D. (2009). Mammalian Target of Rapamycin Is a Critical Regulator of Cardiac Hypertrophy in Spontaneously Hypertensive Rats. Ovid Technologies (Wolters Kluwer Health). Vol. 54(6), 1321-1327. Published, 2009.
  • Guo, Y., Bruno, R.S., Gale, D., Jalili, T., Larson, A.J., Tanner, J. & Symons, J.D. (2009). Acute Quercetin Supplementation Does Not Lower Blood Pressure or Ace Activity in Normotensive Males. Elsevier BV. Vol. 109(9), A16. Published, 2009.
  • Soesanto WS, Lin H, Hu E, Lefler S, Litwin SE, Sena S, Abel ED, Symons JD, Jalili, T mTOR is a critical regulator of cardiac hypertrophy in spontaneously hypertensive rats. Hypertension 54:1321-1327, 2009.. Published, 10/2009.
  • Carlstrom J, Symons JD, Wu TC, Bruno RS, Litwin SE, Jalili T. A quercetin supplemented diet does not prevent cardiovascular complications in spontaneously hypertensive rats. Journal of Nutrition, 137:628-633, 2007. Published, 07/2007.
  • Edwards RL, Lyon T, Litwin SE, Rabovsky A, Symons JD, Jalili T. Quercetin Reduces Blood Pressure In Hypertensive Patients. Journal of Nutrition 137:2405-2411, 2007. Published, 07/2007.
  • David Symons, J., Kim, Sun, Freeman, David, Carlstrom, Justin, Wu, Tzu-Ching, Litwin, Sheldon E., Jalili, Thunder & Jin, Huifeng (2006). Quercetin-Supplemented Diets Lower Blood Pressure and Attenuate Cardiac Hypertrophy in Rats With Aortic Constriction. Ovid Technologies (Wolters Kluwer Health). Vol. 47(4), 531-541. Published, 2006.
  • Jalili T, Carlstrom JA, Kim S, Freeman D, Jin H, Wu TC, Litwin SE, Symons JD. Quercetin supplemented diets lower blood pressure and attenuate cardiac hypertrophy in rats with aortic constriction. Journal of Cardiovascular Pharmacology, 47(4)531-541, 2006. Published, 07/2006.
  • Itoh, S. (2005). Role of p90 Ribosomal S6 Kinase (p90RSK) in Reactive Oxygen Species and Protein Kinase C (PKC- )-mediated Cardiac Troponin I Phosphorylation. American Society for Biochemistry & Molecular Biology (ASBMB). Vol. 280(25), 24135-24142. Published, 2005.
  • Arvizo, Joel, Avelar, Erick, Mattson, John P, Hu, Ping, Jalili, Thunder, Dong, Li & Litwin, Sheldon E (2005). . Springer Science + Business Media. Vol. 5(1), 6. Published, 2005.
  • Jalili T, Avelar E, Dong Li, Arvizo J, Hu P, Litwin SE, Mattson J. PKC translocation and ERK 1/2 activation in compensated right ventricular hypertrophy secondary to chronic emphysema. BMC Physiology, 5:6, 2005. Published, 09/2005.
  • Itoh S, Ding B, Bains CP, Wang N, Takeishi Y, Jalili T, King GL, Walsh RA, Yan C, Abe J. Role of p90 Ribosomal S6 Kinase (p90RSK) in reactive oxygen species and PKCβ-mediated cardiac Troponin I phosphorylation. Journal of Biological Chemistry, 80(25):24135-42, 2005. Published, 06/2005.
  • Jalili, Thunder, Moyer-Mileur, Laurie J., Miller, Scott C., Heap, Jenny & Murray, Mary A. (2004). Alterations in bone characteristics associated with glycemic control in adolescents with type 1 diabetes mellitus. Elsevier BV. Vol. 144(1), 56-62. Published, 2004.
  • Heap J, Murray MA, Miller SC, Jalili T, Moyer-Mileur LJ. Alterations In Bone Characteristics Associated With Glycemic Control In Type 1 Diabetes Mellitus Adolescents. Journal of Pediatrics, 144 (1):56-62, 2004. Published, 04/2004.
  • Jalili T, Manning J, Kim S. Increased translocation of cardiac protein kinase C β2 accompanies mild cardiac hypertrophy in rats fed saturated fat. Journal of Nutrition, 133:358-361, 2003. Published, 02/2003.
  • DiSilvestro RA, Wildman REC, Jalili T, Medeiros DM, Hitchcock C. Long Term Marginal Copper Intake by Rats: Effects on Copper Enzyme Activities and Responses to Dimethylhydrazine. Journal of Trace Elements in Experimental Medicine. 13:359-65, 2000. Published, 11/2000.
  • Jalili T, Wildman REC. Nutraceutical roles of dietary fiber. Journal of Functional and Medicinal Foods. 2 (4):19-34, 2000. Published, 10/2000.
  • Jalili T, Takeishi Y, Song G, Ball N, Howles G, Walsh RA. Protein kinase C translocation without changes in Gαq and PLC βI protein abundance in cardiac hypertrophy and failure. American Journal of Physiology; Heart and Circulatory Physiology, 277:H2298-2304, 1999. Published, 09/1999.
  • Takeishi Y, Jalili T, Kirkpatrick DL, Wagoner LE, Abraham WT, Walsh RA. Differential alterations in Ca2+ cycling proteins and protein kinase C signaling after left ventricular assist device support in failing human hearts. Cardiovascular Research, 45:883-888, 2000. Published, 06/1999.
  • Takeishi Y, Jalili T, Ball NA, Walsh RA. Responses of protein kinase C isoforms to distinct pathologic stimuli are differentially regulated in guinea pig hearts. Circulation Research, 85:264-271, 1999. Published, 05/1999.
  • Jalili T, Takeishi Y, Walsh RA. Re-evaluating the role of G alpha q and protein kinase C signal transduction in cardiac hypertrophy. Cardiovascular Research, 44:5-9, 1999. Published, 03/1999.
  • Jalili T, Gazula GG, Schiestl RH. Cigarette smoke exposure induces DNA deletions in the mouse embryo. Cancer Research, 58:2633-2638, 1998. Published, 10/1998.
  • Jalili T, Medeiros DM, Prochaska L. Alterations in cardiac cytochrome c oxidase, but not in cardiac laminin and fibronectin are observed within three weeks of copper restriction in rats: possible implications for cardiac hypertrophy. Nutrition Research, 17:493-504, 1997. Published, 02/1997.
  • Jalili T, Medeiros DM, Wildman REC. Aspects of cardiomyopathy are exacerbated by elevated dietary fat in copper restricted rats. Journal of Nutrition, 126:807-816, 1996. Published, 04/1996.