Lisa Joss-Moore
  • Research Professor, Pediatrics
  • Assistant Professor (Lecturer), Nutrition & Integrative Physiology
801-587-7486

Research Summary

The Joss-Moore Lab studies how perinatal insults affect essential fatty acid driven molecular mechanisms predisposing to lung disease. We seek to understand contributions from the placenta, epigenetic signaling pathways, and fatty acid sub-types, as well as the mechanisms behind sex-divergent responses. Our studies involve molecular, morphometric, physiologic and genomic approaches. Our research is supported by the National Institutes of Health, and Primary Children’s Hospital Foundation.

Education

  • Master's, Nutrition, University of Utah
  • Postdoctoral Fellow, Biochemistry, University of Utah
  • Doctor of Philosophy, Biochemistry, University of Sydney
  • Bachelor of Science, Biochemistry, University of Sydney

Biography

Dr Joss-Moore is a Professor in the Department of Pediatrics. Dr Joss-Moore focus is research and education. Dr Joss-Moore received a PhD in Biochemistry from University of Sydney, and a Master’s degree in Nutrition from the University of Utah. She began a faculty appointment with the Department of Pediatrics, University of Utah in 2007.  Dr Joss-Moore’s research program is centered on the interplay between fatty acid signaling, epigenetics, and the developmental origins of health and disease (DOHaD). Much of Dr Joss-Moore’s focus is identification of fatty acid responsive epigenetic pathways that are active during development. A molecular emphasis is the transcriptional regulator, PPARγ. She uses an integrated approach involving molecular, morphometric, physiologic and genomic methods to understand the complexity of molecular events as they relate to disease.  The long-term goal of Dr Joss-Moore’s research program is to understand the mechanisms by which fatty acid responsive epigenetic pathways alter developmental trajectories in the short and long-term, in order to inform targeted, fatty acid based therapeutic approaches. Her research is supported by the NIH. Dr Joss-Moore is also engaged in education and development, particularly of the physician-scientist. She is Director of the Pre-Award Office for the Department of Pediatrics ‘Pediatric Research Enterprise’. She also teaches grant and manuscript writing locally and nationally, as well as graduate level genetic and epigenetic nutritional biochemistry.