- Sendi MSE, Inman CS, Bijanki KR & Blanpain L (2022). Identifying the neurophysiological effects of memory-enhancing amygdala stimulation using interpretable machine learning. Brain stimulation. Vol. 14, 1511-1519. Published, 03/01/2022.
- Stangl M, Topalovic U, Inman CS, Hiller S, Villaroman D, Aghajan ZM, Christov-Moore L, Hasulak NR, Rao VR, Halpern CH, Eliashiv D, Fried I & Suthana N (2021). Boundary-anchored neural mechanisms of location-encoding for self and others. Nature. Vol. 589, 420-425. Published, 02/01/2021.
- Bijanki KR, van Rooij SJH, Ely TD, Stevens JS, Inman CS, Fasano RE, Carter SE, Winters SJ, Baman JR, Drane DL, Jovanovic T & Willie JT (2021). Case Series: Unilateral Amygdala Ablation Ameliorates Post-Traumatic Stress Disorder Symptoms and Biomarkers. Neurosurgery. Vol. 87, 796-802. Published, 01/01/2021.
- Topalovic U, Aghajan ZM, Villaroman D, Hiller S, Christov-Moore L, Wishard TJ, Stangl M, Hasulak NR, Inman CS, Fields TA, Rao VR, Eliashiv D, Fried I & Suthana N (2020). Wireless Programmable Recording and Stimulation of Deep Brain Activity in Freely Moving Humans. Neuron. Vol. 108, 322-334.e9. Published, 12/01/2020.
- Tsitsiklis M, Miller J, Qasim SE, Inman CS, Gross RE, Willie JT, Smith EH, Sheth SA, Schevon CA, Sperling MR, Sharan A, Stein JM & Jacobs J (2020). Single-Neuron Representations of Spatial Targets in Humans. Current biology : CB. Vol. 30, 245-253.e4. Published, 11/01/2020.
- Inman CS, Bijanki KR, Bass DI, Gross RE, Hamann S & Willie JT (2020). Human amygdala stimulation effects on emotion physiology and emotional experience. Neuropsychologia. Vol. 145, 106722. Published, 10/01/2020.
- Sendi MSE, Kanta V, Inman CS, Manns JR, Hamann S, Gross RE, Willie JT & Mahmoudi B (2020). Amygdala Stimulation Leads to Functional Network Connectivity State Transitions in the Hippocampus. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. Vol. 2020, 3625-3628. Published, 10/01/2020.
- Hanslmayr S, Axmacher N & Inman CS (2020). Modulating Human Memory via Entrainment of Brain Oscillations. Trends in neurosciences. Vol. 42, 485-499. Published, 09/01/2020.
- Solomon EA, Stein JM, Das S, Gorniak R, Sperling MR, Worrell G, Inman CS, Tan RJ, Jobst BC, Rizzuto DS & Kahana MJ (2020). Dynamic Theta Networks in the Human Medial Temporal Lobe Support Episodic Memory. Current biology : CB. Vol. 29, 1100-1111.e4. Published, 04/01/2020.
- Bijanki KR, Manns JR, Inman CS, Choi KS, Harati S, Pedersen NP, Drane DL, Waters AC, Fasano RE, Mayberg HS & Willie JT (2020). Cingulum stimulation enhances positive affect and anxiolysis to facilitate awake craniotomy. The Journal of clinical investigation. Vol. 129, 1152-1166. Published, 02/01/2020.
- Qasim SE, Miller J, Inman CS, Gross RE, Willie JT, Lega B, Lin JJ, Sharan A, Wu C, Sperling MR, Sheth SA, McKhann GM, Smith EH, Schevon C, Stein JM & Jacobs J (2020). Memory retrieval modulates spatial tuning of single neurons in the human entorhinal cortex. Nature neuroscience. Vol. 22, 2078-2086. Published, 01/01/2020.
- Riva-Posse P, Inman CS, Choi KS, Crowell AL, Gross RE, Hamann S & Mayberg HS (2019). Autonomic arousal elicited by subcallosal cingulate stimulation is explained by white matter connectivity. Brain stimulation. Vol. 12, 743-751. Published, 07/01/2019.
- Waldman ZJ, Camarillo-Rodriguez L, Chervenova I, Berry B, Shimamoto S, Elahian B, Kucewicz M, Ganne C, He XS, Davis LA, Stein J, Das S, Gorniak R, Sharan AD, Gross R, Inman CS, Lega BC, Zaghloul K, Jobst BC, Davis KA, Wanda P, Khadjevand M, Tracy J, Rizzuto DS, Worrell G, Sperling M & Weiss SA (2019). Ripple oscillations in the left temporal neocortex are associated with impaired verbal episodic memory encoding. Epilepsy & behavior : E&B. Vol. 88, 33-40. Published, 05/01/2019.
- Inman CS, James GA, Vytal K & Hamann S (2019). Dynamic changes in large-scale functional network organization during autobiographical memory retrieval. Neuropsychologia. Vol. 110, 208-224. Published, 01/01/2019.
- Ezzyat Y, Kragel JE, Burke JF, Levy DF, Lyalenko A, Wanda P, O'Sullivan L, Hurley KB, Busygin S, Pedisich I, Sperling MR, Worrell GA, Kucewicz MT, Davis KA, Lucas TH, Inman CS, Lega BC, Jobst BC, Sheth SA, Zaghloul K, Jutras MJ, Stein JM, Das SR, Gorniak R, Rizzuto DS & Kahana MJ (2018). Direct Brain Stimulation Modulates Encoding States and Memory Performance in Humans. Current biology : CB. Vol. 27, 1251-1258. Published, 08/01/2018.
- Inman CS, Manns JR, Bijanki KR, Bass DI, Hamann S, Drane DL, Fasano RE, Kovach CK, Gross RE & Willie JT (2018). Direct electrical stimulation of the amygdala enhances declarative memory in humans. Proceedings of the National Academy of Sciences of the United States of America. Vol. 115, 98-103. Published, 07/01/2018.
- Bauer PJ, Pathman T, Inman C, Campanella C & Hamann S (2018). Neural correlates of autobiographical memory retrieval in children and adults. Memory (Hove, England). Vol. 25, 450-466. Published, 04/01/2018.
- Kragel JE, Ezzyat Y, Sperling MR, Gorniak R, Worrell GA, Berry BM, Inman C & Lin JJ (2018). Similar patterns of neural activity predict memory function during encoding and retrieval. NeuroImage. Vol. 155, 60-71. Published, 04/01/2018.
- Reidy BL, Hamann S, Inman C, Johnson KC & Brennan PA (2016). Decreased sleep duration is associated with increased fMRI responses to emotional faces in children. Neuropsychologia. Vol. 84, 54-62. Published, 12/01/2016.
- Inman CS, James GA, Hamann S, Rajendra JK, Pagnoni G & Butler AJ (2012). Altered resting-state effective connectivity of fronto-parietal motor control systems on the primary motor network following stroke. NeuroImage. Vol. 59, 227-37. Published, 02/01/2012.
I am interested in how the human brain makes real, rich, complex memories that last and working on ways to fix episodic memory when it fails. The ultimate goal of the lab is to explain real-world behavior in terms of the activities of the brain and to translate these discoveries into therapeutic approaches that can help those suffering from neural disorders. My laboratory performs studies that dissect the emotion and memory functions of the human brain across three complimentary lines of research focused on:
- Understanding the dynamic organization of neural circuits from single neurons to whole brain networks during emotion and memory processes using human intracranial electrophysiology and functional neuroimaging,
- Modulating the activity and organization of these networks to gain control of emotional experience or enhance memory using direct brain stimulation in humans, and
- Translating these laboratory-based discoveries to neuromodulation therapies that can restore functional behavior in real-world settings to help those suffering with neural disorders.
My research draws upon theoretical perspectives and experimental techniques from multiple fields, including network neuroscience, cognitive science, neuroengineering, virtual reality (VR), augmented reality (AR), human neurophysiology, and neuromodulation. The lab's research program is constructed upon studies using behavioral, neuroimaging, and neuromodulation approaches to study how the brain operates in traditional laboratory experiments with the explicit objective to gradually work towards neuroscience studies of real-world cognitive behaviors that extend from laboratory-based discoveries. With the promise shown by recent neuromodulation studies aimed at treating a variety of memory and mood disorders (e.g. Inman, Manns, et al., 2018, PNAS; Ezzyat et al., 2017, 2018; Riva-Posse, Inman et al., 2019, Brain Stimulation), working towards neuroscientific studies of real-world cognition is the key translational step needed to push our insights from the laboratory to restoring real-life cognitive function in those suffering from devastating disorders of emotion and memory.
In order to work with epilepsy patients that have implanted recording and stimulation electrodes to monitor and treat their seizures, our lab works closely with the Neurosurgery and Neurology departments at the University of Utah. Specifically, we work directly with John Rolston, MD, PhD (Neurosurgeon, Rolston Lab), and Elliot Smith, PhD among other neurosurgeons across the country.
Fundamental questions my lab will examine include:
- How does the brain respond to experiences in the real-world and can direct brain stimulation enhance memory for real-world experiences?
- How does amygdala stimulation affect activity in other parts its connected network and how do these changes relate to emotional behavior?
- How does oscillatory activity in the brain reorganize as people retrieve autobiographical memories?
- Memory Enhancement
- Intracranial EEG
- Human Learning and Memory
- Functional neuroimaging of human cognition
- Functional MRI
- Deep Brain Stimulation
- Brain Computer Interfaces
- "Modulation of emotion and memory with direct brain stimulation in humans: From the laboratory into the wild", American Society for Stereotactic and Functional Neurosurgery, Atlanta, GA. Invited Talk/Keynote, Accepted, 06/07/2022.
- "Capturing and enhancing episodic memories made in the wild", Eastern Carolina University, Department of Engineering. Invited Talk/Keynote, Presented, 01/28/2022.
- "Capturing and enhancing episodic memories made in the wild", Neurobiology of Learning and Memory Winter Meeting, Symposium on “Emotion and Memory in the Wild,” Chair. Invited Talk/Keynote, Presented, 01/08/2022.
- "Capturing and enhancing episodic memories made in the wild", University College London, Welcomme Center for Human Neuroimaging, Translational Neurophysiology Group. Invited Talk/Keynote, Presented, 12/08/2021.
- "Capturing and enhancing episodic memories made in the wild", University of California, San Diego, Voytek Lab. Invited Talk/Keynote, Presented, 11/17/2021.
- "Modulation of emotion and memory with direct brain stimulation in humans: From the laboratory into the wild", University of Freiburg, Freiburg Epilepsy Center, Department of Neurosurgery. Invited Talk/Keynote, Presented, 07/13/2021.
- "Capturing and enhancing episodic memories made in the wild", University of Utah, Department of Neurobiology. Invited Talk/Keynote, Presented, 05/05/2021.
- "The Cognitive Neuroscience of Emotion and Memory: From the Laboratory into the Wild", University of New Mexico, Neurosciences Seminar Series. Invited Talk/Keynote, Presented, 04/29/2021.
- "The Cognitive Neuroscience of Emotion and Memory: From the Laboratory into the Wild", Providence College, Department of Psychology. Invited Talk/Keynote, Presented, 03/09/2021.
- "The Cognitive Neuroscience of Emotion and Memory: From the Laboratory into the Wild", University of Utah, Department of Health and Kinesiology . Invited Talk/Keynote, Presented, 01/29/2021.
- "Direct electrical stimulation of the amygdala enhances declarative memory in humans", Neuromatch 2.0. Presentation, Presented, 05/27/2020.
- "Modulation of Emotion and Memory via Direct Brain Stimulation in Humans: From the Laboratory into the Wild", Emotion and Social Cognition Lab, California Institute of Technology. Invited Talk/Keynote, Presented, 04/06/2020.
- "Modulation of Emotion and Memory via Direct Brain Stimulation in Humans: From the Laboratory into the Wild", UCLA Integrative Center for Learning and Memory Journal Club. Invited Talk/Keynote, Presented, 01/20/2020.
- "Modulation of Emotion and Memory via Direct Brain Stimulation in Humans: From the Laboratory into the Wild", Rutishauser Laboratory of Systems Neuroscience, Cedars Sinai, California Institute of Technology. Invited Talk/Keynote, Presented, 07/10/2019.
- Krista Wahlstrom, Ph.D., Postdoc. Psychology Department. 11/10/2021 - present.
- Anxiolysis without sedation: Awake craniotomy facilitated by continuous direct stimulation of cingulum bundle (#11,241,575 B1). Status: Published. Inventors: Bijanki, K.R., Inman, C.S., Pedersen, N.P., Willie, J.T. File date 09/05/2018; Issue date 02/08/2022. Country: United States.