Publications

  • Manna S, Kimoto M, Truong J, Bommisetti P, Peitz A, Hirao I & Hammond MC (2023). Systematic Mutation and Unnatural Base Pair Incorporation Improves Riboswitch-Based Biosensor Response Time. ACS Sensors. Published, 12/2023.
  • Squire S, Sebghati S & Hammond MC (2023). Cytoplasmic Accumulation and Permeability of Antibiotics in Gram Positive and Gram Negative Bacteria Visualized in Real-Time via a Fluorogenic Tagging Strategy. ACS Chemical Biology. Published, 12/2023.
  • Banuelos-Jara, B & Hammond, M. C. (2023). Natural Riboswitches. Springer. Published, 04/2023.
  • Manna S (2021). Guanidine Biosensors Enable Comparison of Cellular Turn-on Kinetics of Riboswitch-Based Biosensor and Reporter. ACS synthetic biology. Vol. 10, 566-578. Published, 11/01/2021.
  • Manna, S., Kellenberger, C. A., Hallberg, Z. F. & Hammond, M. C. (2021). Live cell imaging using riboswitch-spinach tRNA fusions as metabolite-sensing fluorescent biosensors. (pp. 121-140). Vol. 2323, Springer. Published, 06/01/2021.
  • Kitto RZ, Dhillon Y, Bevington B, Horne M, Giege P, Drouard L, Heintz D, Villette C, Corre N, Arrive M, Manfield MJ, Bowman R, Favier JJ, Osborne B, Welch C, McKay CP & Hammond MC (2021). Synthetic biological circuit tested in spaceflight. Life Sciences in Space Research. Vol. 28, 57-65. Published, 02/01/2021.
  • Kitto RZ & Christiansen KE, Hammond MC (2020). RNA‐based fluorescent biosensors for live cell detection of bacterial sRNA. Biopolymers. Vol. 112. Published, 08/12/2020.
  • Palmer AE & Hammond MC (2020). Editorial overview: Molecular imaging. (pp. A5-A7). Vol. 57. Current Opinion in Biotechnology. Published, 08/01/2020.
  • Su Y & Hammond MC (2020). RNA-based fluorescent biosensors for live cell imaging of small molecules and RNAs. (pp. 157-166). Vol. 63. Current Opinion in Biotechnology. Published, 06/01/2020.
  • Anderson WA & Dippel AB, Maiden MM, Waters CM, Hammond MC (2020). Chemiluminescent sensors for quantitation of the bacterial second messenger cyclic di-GMP. (pp. 83-104). Vol. 640, Methods in Enzymology. Published, 05/30/2020.
  • Li Y & Fin A, Rovira AR, Su Y, Dippel AB, Valderrama JA, Riestra AM, Nizet V, Hammond MC, Tor Y (2020). Tuning the Innate Immune Response to Cyclic Dinucleotides by Using Atomic Mutagenesis. ChemBioChem. Vol. 21, 2595-2598. Published, 04/28/2020.
  • Dippel AB & Anderson WA, Park JH, Yildiz FH, Hammond MC (2020). Development of ratiometric bioluminescent sensors for in vivo detections of bacterial signaling. ACS Chemical Biology. Vol. 15, 904-914. Published, 03/18/2020.
  • Wright TA, Jiang L, Park JJ, Anderson WA, Chen G, Hallberg ZF, Nan B & Hammond MC (2020). Second messengers and divergent HD-GYP phosphodiesterases regulate 3',3'-cGAMP signaling. Molecular microbiology. Vol. 113, 222-236. Published, 02/01/2020.
  • Wright TA, Dippel, AB & Hammond, MC (2020). Cyclic di-GMP signaling gone astray: cGAMP signaling via Hypr GGDEF and HD-GYP enzymes. Springer Nature. Published, 02/01/2020.
  • Dippel AB & Hammond MC (2019). A Poxin on Both of Your Houses: Poxviruses Degrade the Immune Signal cGAMP. Biochemistry. Vol. 58, 2387-2388. Published, 11/01/2019.
  • Villa JK, Su Y, Contreras LM & Hammond MC (2019). Synthetic Biology of Small RNAs and Riboswitches. Vol. 6. Microbiology spectrum. Published, 01/01/2019.
  • Truong J, Hsieh YF, Truong L, Jia G & Hammond MC (2018). Designing fluorescent biosensors using circular permutations of riboswitches. Methods (San Diego, Calif.). Vol. 143, 102-109. Published, 12/01/2018.
  • Yeo J, Wang XC & Hammond MC (2018). Live Flow Cytometry Analysis of c-di-GMP Levels in Single Cell Populations.. (pp. 111-130). Vol. 1657, Methods in molecular biology (Clifton, N.J.). Published, 05/01/2018.
  • Yeo J, Dippel AB, Wang XC & Hammond MC (2018). In Vivo Biochemistry: Single-Cell Dynamics of Cyclic Di-GMP in Escherichia coli in Response to Zinc Overload. Biochemistry. Vol. 57, 108-116. Published, 05/01/2018.
  • Dippel AB, Anderson WA, Evans RS, Deutsch S & Hammond MC (2018). Chemiluminescent Biosensors for Detection of Second Messenger Cyclic di-GMP. ACS chemical biology. Vol. 13, 1872-1879. Published, 02/18/2018.
  • Hallberg ZF, Su Y, Kitto RZ & Hammond MC (2017). Engineering and In Vivo Applications of Riboswitches. (pp. 515-539). Vol. 86. Annual review of biochemistry. Published, 07/01/2017.
  • Bose D, Su Y, Marcus A, Raulet DH & Hammond MC (2016). An RNA-Based Fluorescent Biosensor for High-Throughput Analysis of the cGAS-cGAMP-STING Pathway. Cell chemical biology. Vol. 23, 1539-1549. Published, 11/23/2016.
  • Wang XC, Wilson SC & Hammond MC (2016). Next-generation RNA-based fluorescent biosensors enable anaerobic detection of cyclic di-GMP. Nucleic acids research. Vol. 44, e139. Published, 09/30/2016.
  • Kellenberger CA, Sales-Lee J, Pan Y, Gassaway MM, Herr AE & Hammond MC (2016). A minimalist biosensor: Quantitation of cyclic di-GMP using the conformational change of a riboswitch aptamer. RNA biology. Vol. 12, 1189-97. Published, 09/01/2016.
  • Hallberg ZF, Wang XC, Wright TA, Nan B, Ad O, Yeo J & Hammond MC (2016). Hybrid promiscuous (Hypr) GGDEF enzymes produce cyclic AMP-GMP (3', 3'-cGAMP). Proceedings of the National Academy of Sciences of the United States of America. Vol. 113, 1790-5. Published, 07/01/2016.
  • Su Y, Hickey SF, Keyser SG & Hammond MC (2016). In Vitro and In Vivo Enzyme Activity Screening via RNA-Based Fluorescent Biosensors for S-Adenosyl-l-homocysteine (SAH). Journal of the American Chemical Society. Vol. 138, 7040-7. Published, 05/18/2016.
  • Ren A, Wang XC, Kellenberger CA, Rajashankar KR, Jones RA, Hammond MC & Patel DJ (2016). Structural basis for molecular discrimination by a 3',3'-cGAMP sensing riboswitch. Cell reports. Vol. 11, 1-12. Published, 01/01/2016.
  • Muller RY, Hammond MC, Rio DC & Lee YJ (2015). An Efficient Method for Electroporation of Small Interfering RNAs into ENCODE Project Tier 1 GM12878 and K562 Cell Lines. Journal of biomolecular techniques : JBT. Vol. 26, 142-9. Published, 12/2015.
  • Gonzalez TL, Liang Y, Nguyen BN, Staskawicz BJ, Loqué D & Hammond MC (2015). Tight regulation of plant immune responses by combining promoter and suicide exon elements. Nucleic acids research. Vol. 43, 7152-61. Published, 11/01/2015.
  • Kellenberger CA & Hammond MC (2015). In vitro analysis of riboswitch-Spinach aptamer fusions as metabolite-sensing fluorescent biosensors.. (pp. 147-72). Vol. 550, Methods in enzymology. Published, 09/01/2015.
  • Pan Y, Duncombe TA, Kellenberger CA, Hammond MC & Herr AE (2015). High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions. Analytical chemistry. Vol. 86, 10357-64. Published, 09/01/2015.
  • Kellenberger CA, Wilson SC, Hickey SF, Gonzalez TL, Su Y, Hallberg ZF, Brewer TF, Iavarone AT, Carlson HK, Hsieh YF & Hammond MC (2015). GEMM-I riboswitches from Geobacter sense the bacterial second messenger cyclic AMP-GMP. Proceedings of the National Academy of Sciences of the United States of America. Vol. 112, 5383-8. Published, 07/01/2015.
  • Kellenberger CA, Hallberg ZF & Hammond MC (2015). Live Cell Imaging Using Riboswitch-Spinach tRNA Fusions as Metabolite-Sensing Fluorescent Biosensors.. (pp. 87-103). Vol. 1316, Methods in molecular biology (Clifton, N.J.). Published, 06/2015.
  • Kellenberger CA, Chen C, Whiteley AT, Portnoy DA & Hammond MC (2015). RNA-Based Fluorescent Biosensors for Live Cell Imaging of Second Messenger Cyclic di-AMP. Journal of the American Chemical Society. Vol. 137, 6432-5. Published, 05/12/2015.
  • Hickey SF & Hammond MC (2014). Structure-guided design of fluorescent S-adenosylmethionine analogs for a high-throughput screen to target SAM-I riboswitch RNAs. Chemistry & biology. Vol. 21, 345-56. Published, 11/01/2014.
  • Wilson SC, Cohen DT, Wang XC & Hammond MC (2014). A neutral pH thermal hydrolysis method for quantification of structured RNAs. RNA (New York, N.Y.). Vol. 20, 1153-60. Published, 08/01/2014.
  • Diner EJ, Burdette DL, Wilson SC, Monroe KM, Kellenberger CA, Hyodo M, Hayakawa Y, Hammond MC & Vance RE (2013). The innate immune DNA sensor cGAS produces a noncanonical cyclic dinucleotide that activates human STING. Cell reports. Vol. 3, 1355-61. Published, 12/01/2013.
  • Karns K, Vogan JM, Qin Q, Hickey SF, Wilson SC, Hammond MC & Herr AE (2013). Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding function. Journal of the American Chemical Society. Vol. 135, 3136-43. Published, 08/01/2013.
  • Leppek K, Schott J, Reitter S, Poetz F, Hammond MC & Stoecklin G (2013). Roquin promotes constitutive mRNA decay via a conserved class of stem-loop recognition motifs. Cell. Vol. 153, 869-81. Published, 07/01/2013.
  • Kellenberger CA, Wilson SC, Sales-Lee J & Hammond MC (2013). RNA-based fluorescent biosensors for live cell imaging of second messengers cyclic di-GMP and cyclic AMP-GMP. Journal of the American Chemical Society. Vol. 135, 4906-9. Published, 03/14/2013.
  • Hickey SF, Sridhar M, Westermann AJ, Qin Q, Vijayendra P, Liou G & Hammond MC (2012). Transgene regulation in plants by alternative splicing of a suicide exon. Nucleic acids research. Vol. 40, 4701-10. Published, 07/01/2012.
  • Meyer MM, Hammond MC, Salinas Y, Roth A, Sudarsan N & Breaker RR (2011). Challenges of ligand identification for riboswitch candidates. RNA biology. Vol. 8, 5-10. Published, 09/01/2011.
  • Hammond MC (2011). RNA folding: a tale of two riboswitches. (pp. 342-3). Vol. 7. Nature chemical biology. Published, 07/01/2011.
  • Block KF, Hammond MC & Breaker RR (2010). Evidence for widespread gene control function by the ydaO riboswitch candidate. Journal of bacteriology. Vol. 192, 3983-9. Published, 08/01/2010.
  • Hammond MC, Wachter A & Breaker RR (2009). A plant 5S ribosomal RNA mimic regulates alternative splicing of transcription factor IIIA pre-mRNAs. Nature structural & molecular biology. Vol. 16, 541-9. Published, 05/01/2009.
  • Weinberg Z, Regulski EE, Hammond MC, Barrick JE, Yao Z, Ruzzo WL & Breaker RR (2008). The aptamer core of SAM-IV riboswitches mimics the ligand-binding site of SAM-I riboswitches. RNA (New York, N.Y.). Vol. 14, 822-8. Published, 05/01/2008.
  • Hammond MC, Harris BZ, Lim WA & Bartlett PA (2007). Beta strand peptidomimetics as potent PDZ domain ligands. Chemistry & biology. Vol. 13, 1247-51. Published, 07/01/2007.
  • Hammond MC & Bartlett PA (2007). Synthesis of amino acid-derived cyclic acyl amidines for use in beta-strand peptidomimetics. The Journal of organic chemistry. Vol. 72, 3104-7. Published, 05/01/2007.
  • Sudarsan N, Hammond MC, Block KF, Welz R, Barrick JE, Roth A & Breaker RR (2006). Tandem riboswitch architectures exhibit complex gene control functions. Science (New York, N.Y.). Vol. 314, 300-4. Published, 10/01/2006.

Presentations

  • Recruiting Talk: Utah Tech. Invited Talk/Keynote, Presented, 12/2023.
  • Recruiting Talk: Southwestern University. Invited Talk/Keynote, Presented, 11/2023.
  • Wenner-Gren Symposium on small molecule signaling across the tree of life with a focus on nucleotide signaling. Invited Talk/Keynote, Presented, 08/2023.
  • Synthetic Biology Gordon Research Conference. Invited Talk/Keynote, Presented, 07/2023.
  • Bioorganic Chemistry Gordon Research Conference. Invited Talk/Keynote, Presented, 06/2023.
  • RNA Nanotechnology Gordon Conference. Invited Talk/Keynote, Presented, 01/09/2023.
  • Recruiting Talk: MSU Denver. Invited Talk/Keynote, Presented, 12/02/2022.
  • Recruiting Talk: Westminster College. Invited Talk/Keynote, Presented, 11/30/2022.
  • NIH Biochemistry and Structural Biology Seminar. Invited Talk/Keynote, Presented, 10/11/2022.
  • Telluride Workshop on Nucleic Acid Chemistry. Invited Talk/Keynote, Presented, 07/24/2022.
  • OHSU Chemical Biology & Physiology Symposium. Invited Talk/Keynote, Presented, 04/30/2022.
  • Department of Chemistry and Chemical Biology, University of Rochester. Invited Talk/Keynote, Presented, 02/2022.
  • Bristol Myer Squibb. Invited Talk/Keynote, Presented, 02/2022.
  • Functional Nucleic Acids Symposium, Pacifichem. Invited Talk/Keynote, Presented, 12/2021.
  • Department of Bioengineering, University of Utah. Invited Talk/Keynote, Presented, 12/2021.
  • Department of Biology, University of Utah. Invited Talk/Keynote, Presented, 12/2021.
  • Activity-Based Sensing Symposium, Pacifichem. Invited Talk/Keynote, Presented, 12/2021.
  • Analytical Chemistry seminar, Department of Chemistry, UC Riverside. Invited Talk/Keynote, Presented, 10/2021.
  • Keynote, German Conference on Synthetic Biology. Invited Talk/Keynote, Presented, 09/2021.
  • Biosensors and Nanodevices, Molecular Foundry User Meeting. Invited Talk/Keynote, Presented, 08/2021.
  • RPT Seminar, Department of Chemistry, University of Utah. Invited Talk/Keynote, Presented, 05/2021.
  • Chemical Epigenetics Seminar, Ludwig Maxmillians University, Munich, Germany. Invited Talk/Keynote, Presented, 04/2021.
  • Chemistry Graduate Student Symposium, University of Utah. Invited Talk/Keynote, Presented, 02/2021.
  • qBio Program, University of California, San Diego. Invited Talk/Keynote, Presented, 12/2020.
  • Chemistry of Life Processes Institute, Northwestern University. Invited Talk/Keynote, Presented, 03/2020.
  • Sensory Transduction in Microorganisms Gordon Conference. Invited Talk/Keynote, Presented, 01/2020.
  • Google X. Invited Talk/Keynote, Presented, 11/2019.
  • New England Biolabs (MA). Invited Talk/Keynote, Presented, 10/2019.
  • NSF SynBioMat Square Table Workshop. Panel, Presented, 10/2019.
  • Telluride Workshop in Aqueous Supramolecular Chemistry (Telluride, CO). Invited Talk/Keynote, Presented, 08/2019.
  • Nucleosides, Nucleotides, and Oligonucleotides Gordon Research Conference (Newport, RI). Poster, Presented, 06/2019.
  • Triple I Initiative, University of Utah. Invited Talk/Keynote, Presented, 04/26/2019.
  • Department of Pharmacy, University of Utah. Invited Talk/Keynote, Presented, 04/15/2019.
  • Concordia University (Montreal, Canada). Invited Talk/Keynote, Presented, 03/14/2019.
  • INRE Institute (Montreal, Canada). Invited Talk/Keynote, Presented, 03/12/2019.
  • Targeting RNA Symposium, National American Chemical Society Meeting (Orlando, FL). Invited Talk/Keynote, Presented, 03/2019.
  • "Technology Innovations" session, Bacterial Locomotion and Signal Transduction meeting. Invited Talk/Keynote, Presented, 01/2019.
  • Center for Cell and Genome Science Symposium, University of Utah. Invited Talk/Keynote, Presented, 10/2018.
  • International Symposium on Nucleotide Second Messenger Signaling in Bacteria (Berlin, Germany). Contributed Talk, Presented, 09/2018.
  • AIR Diversity fellowship symposium, Pfizer La Jolla. Invited Talk/Keynote, Presented, 09/2018.
  • NYU-Nature Conference on Chemical Biology. Invited Talk/Keynote, Presented, 08/2018.
  • “Seeing is Believing” session, American Society of Microbiology. Invited Talk/Keynote, Presented, 06/2018.
  • Bioorganic Chemistry Gordon Conference. Invited Talk/Keynote, Presented, 06/2018.
  • FNano – Foundations of Nanoscience Conference (Snowbird, Utah). Invited Talk/Keynote, Presented, 04/2018.
  • Department of Genetics seminar, University of Minnesota. Invited Talk/Keynote, Presented, 04/2018.
  • “Discovery of Small Molecules Targeting RNA” session, American Chemical Society National Meeting. Invited Talk/Keynote, Presented, 03/2018.