Thomas A. Zangle

Thomas A. Zangle portrait
  • Associate Member, Cell Response and Regulation Program, Huntsman Cancer Institute
  • Assistant Professor, Chemical Engineering

Research

Research Summary

Development of approaches to study cancer and develop personalized therapies

Research Statement

The Zangle Lab applies the principles of fluid mechanics and mass transport to study transport in single cells using both established and emerging microscopy techniques. Current work focuses on the use of quantitative phase microscopy (QPM) to quantify mass distributions within single cells and multicellular clusters. The resulting measurements can be used to assess the total mass of, or the transport of mass within, individual cells.

Research Keywords

  • Microscopy, Interest Level: 5
  • Microfluidics, Interest Level: 5
  • Fluid Mechanics, Interest Level: 5
  • Cancer Biology, Interest Level: 4
  • Breast Cancer, Interest Level: 4

Research Groups

  • Nicholas Western, Undergraduate Student. Chemical Engineering. 11/14/2016 - present.

Research Equipment and Testing Expertise

  • My lab works with quantitative phase microscopy, a label free method to measure the mass of single, living cells.