DANIEL M WITT portrait
  • Department Chair, Pharmacotherapy
  • Professor, Pharmacotherapy
801-581-8851

Publications

  • Witt DM, Clark NP, Martinez K, Schroeder A, Garcia D, Crowther MA, Ageno W, Dentali F, Ye X, Hylek E, Delate T. Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for intracranial hemorrhage. Thrombosis Research 2015;136:1040-1044. Published, 11/2105.
  • Witt DM (2016). What to do after the bleed: resuming anticoagulation after major bleeding. Hematology. American Society of Hematology. Education Program. Vol. 2016, 620-624. Published, 12/01/2016.
  • Witt DM & Hansen AL (2016). Non-Vitamin K Anticoagulant Dose┬áSelection: It's Best to Read and Follow the Directions. Journal of the American College of Cardiology. Vol. 68, 2605-2607. Published, 12/01/2016.
  • Dentali F, Crowther M, Galli M, Pomero F, Garcia D, Clark N, Spadafora L, Witt DM, Ageno W & (2016). Effect of Vitamin K Intake on the Stability of Treatment with Vitamin K Antagonists: A Systematic Review of the Literature. Seminars in thrombosis and hemostasis. Vol. 42, 671-81. Published, 09/01/2016.
  • Li G, Holbrook A, Jin Y, Zhang Y, Levine MA, Mbuagbaw L, Witt DM, Crowther M, Connolly S, Chai-Adisaksopha C, Wan Z, Cheng J & Thabane L (2016). Comparison of treatment effect estimates of non-vitamin K antagonist oral anticoagulants versus warfarin between observational studies using propensity score methods and randomized controlled trials. European journal of epidemiology. Vol. 31, 541-61. Published, 07/01/2016.
  • Fang MC, Fan D, Sung SH, Witt DM, Schmelzer JR, Steinhubl SR, Yale SH, Go AS. Validity of using inpatient and outpatient administrative codes to identify acute venous thromboembolism: the CVRN VTE study. Medical Care 2016; Epub ahead of print. Published, 04/2016.
  • Rose AJ, Delate T, Ozonoff A & Witt DM (2016). Comparison of the Abilities of Summary Measures of International Normalized Ratio Control to Predict Clinically Relevant Bleeding. (pp. 524-31). Vol. 8. Circulation. Cardiovascular quality and outcomes. Published, 01/01/2016.
  • Witt DM, Clark NP, Kaatz S, Schnurr T, Ansell JE. Guidance for the practical management of warfarin therapy in the treatment of venous thromboembolism. Journal of Thrombosis and Thrombolysis 2016;41:187-205. Published, 01/2016.
  • Delate T, Hsiao W, Kim B, Witt DM, Meyer MR, Go AS, Fang MC. Assessment of algorithms to identify patients with thrombophilia following venous thromboembolism. Thrombosis Research 2016;137:97-102. Published, 01/2016.
  • Meyer MR, Witt DM, Delate T, Johnson SG, Fang M, Go A, Clark NP. Thrombophilia testing patterns amongst patients with acute venous thromboembolism. Thrombosis Research 2015;136:1160-1164. Published, 12/2015.
  • Li G, Holbrook A, Delate T, Witt DM, Levine MAH, Thabane L. Prediction of individual combined benefit and harm for patients with atrial fibrillation considering warfarin therapy: a study protocol. BMJ Open 2015:5;e009518. Published, 11/2015.
  • Jenner KM, Simmons BJ, Delate T, Clark NP, Kurz D & Witt DM (2015). An Education Program for Patient Self-Management of Warfarin. The Permanente journal. Vol. 19, 33-8. Published, 10/01/2015.
  • Chai-Adisaksopha C, Hillis C, Monreal M, Witt DM & Crowther M (2015). Thromboembolic events, recurrent bleeding and mortality after resuming anticoagulant following gastrointestinal bleeding. A meta-analysis. Thrombosis and haemostasis. Vol. 114, 819-25. Published, 09/01/2015.
  • Kauffman YS, Schroeder AE & Witt DM (2015). Patient Specific Factors Influencing Adherence to INR Monitoring. Pharmacotherapy. Vol. 35, 740-7. Published, 08/01/2015.
  • Martinez K, Kosirog E, Billups SJ, Clark NP, Delate T & Witt DM (2015). Clinical outcomes and adherence to guideline recommendations during the initial treatment of acute venous thromboembolism. The Annals of pharmacotherapy. Vol. 49, 869-75. Published, 07/01/2015.
  • Clark NP, Witt DM, Davies LE, Saito EM, McCool KH, Douketis JD, Metz KR & Delate T (2015). Bleeding, Recurrent Venous Thromboembolism, and Mortality Risks During Warfarin Interruption for Invasive Procedures. (pp. 1163-8). Vol. 175. JAMA internal medicine. Published, 07/01/2015.
  • Fang MC, Fan D, Sung SH, Witt DM, Yale SH, Steinhubl SR & Go AS (2015). Outcomes in adults with acute pulmonary embolism who are discharged from emergency departments: the Cardiovascular Research Network Venous Thromboembolism study. JAMA internal medicine. Vol. 175, 1060-2. Published, 06/01/2015.
  • Olson KL, Irwin AN, Billups SJ, Delate T, Johnson SG, Kurz D & Witt DM (2015). Impact of a clinical pharmacy research team on pharmacy resident research. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. Vol. 72, 309-16. Published, 01/01/2015.
  • Cho SE, Delate T, Witt DM & Clark NP (2015). Thromboembolic and bleeding outcomes of extended duration low-intensity warfarin following elective total knee arthroplasty. Thrombosis research. Vol. 135, 267-71. Published, 01/01/2015.
  • Nutescu EA, Wittkowsky AK, Witt DM, Kaatz S, Ansell J, Burnett A, Garcia D, Lopes RD, Oertel L, Schnurr T, Streiff M, Wirth D & Crowther M (2014). Integrating electronic health records in the delivery of optimized anticoagulation therapy. (pp. 125-6). Vol. 49. The Annals of pharmacotherapy. Published, 12/01/2014.
  • Wood MD, Delate T, Clark M, Clark N, Horn JR & Witt DM (2014). An evaluation of the potential drug interaction between warfarin and levothyroxine. Journal of thrombosis and haemostasis : JTH. Vol. 12, 1313-9. Published, 08/01/2014.
  • Irwin AN, McCool KH, Delate T & Witt DM (2014). Authors' reply. (pp. e28-9). Vol. 34. Pharmacotherapy. Published, 05/01/2014.
  • Irwin AN, Johnson SG, Joline BR, Delate T & Witt DM (2014). A descriptive evaluation of warfarin use in patients with pulmonary arterial hypertension. (pp. 790-4). Vol. 133. Thrombosis research. Published, 04/01/2014.
  • Clark NP, Delate T, Riggs CS, Witt DM, Hylek EM, Garcia DA, Ageno W, Dentali F, Crowther MA & (2014). Warfarin interactions with antibiotics in the ambulatory care setting. JAMA internal medicine. Vol. 174, 409-16. Published, 03/01/2014.
  • Irwin AN, McCool KH, Delate T & Witt DM (2014). Assessment of warfarin dosing requirements after bariatric surgery in patients requiring long-term warfarin therapy. Pharmacotherapy. Vol. 33, 1175-83. Published, 03/01/2014.
  • Lam J, Schulman S, Witt DM, Vandvik PO, Qayyum F & Holbrook AM (2014). Anticoagulation control with daily low-dose vitamin k to reduce clinically adverse outcomes and international normalized ratio variability: a systematic review and meta-analysis. Pharmacotherapy. Vol. 33, 1184-90. Published, 03/01/2014.
  • Witt DM, Delate T, Hylek EM, Clark NP, Crowther MA, Dentali F, Ageno W, Martinez KD & Garcia DA (2014). Effect of warfarin on intracranial hemorrhage incidence and fatal outcomes. Thrombosis research. Vol. 132, 770-5. Published, 02/01/2014.
  • McGinnis B, Kauffman Y, Olson KL, Witt DM & Raebel MA (2014). Interventions aimed at improving performance on medication adherence metrics. International journal of clinical pharmacy. Vol. 36, 20-5. Published, 01/01/2014.
  • Irwin AN, Olson KL, Joline BR, Witt DM & Patel RJ (2013). Challenges to publishing pharmacy resident research projects from the perspectives of residency program directors and residents. Pharmacy practice. Vol. 11, 166-72. Published, 11/01/2013.
  • Witt DM (2013). Review: rivaroxaban causes less fatal bleeding, but does not reduce mortality, compared with VKAs. (pp. JC13). Vol. 159. Annals of internal medicine. Published, 09/01/2013.
  • Witt DM, Delate T, Clark NP, Garcia DA, Hylek EM, Ageno W, Dentali F & Crowther MA (2013). Nonadherence with INR monitoring and anticoagulant complications. Thrombosis research. Vol. 132, e124-30. Published, 09/01/2013.
  • Witt DM, Delate T & Crowther MA (2013). Resumption of warfarin therapy after gastrointestinal tract bleeding: benefit or bias?--Reply. (pp. 832-3). Vol. 173. JAMA internal medicine. Published, 05/01/2013.
  • Clark NP, Cho SE, Delate T & Witt DM (2013). Thromboembolic and bleeding outcomes of low-intensity warfarin thromboprophylaxis following elective total hip arthroplasty. Thrombosis research. Vol. 131, 390-5. Published, 05/01/2013.
  • Heilmann RM, Campbell SM, Kroner BA, Proksel JR, Billups SJ, Witt DM & Helling DK (2013). Evolution, current structure, and role of a primary care clinical pharmacy service in an integrated managed care organization. The Annals of pharmacotherapy. Vol. 47, 124-31. Published, 01/01/2013.
  • Witt DM, Delate T, Garcia DA, Clark NP, Hylek EM, Ageno W, Dentali F & Crowther MA (2013). Risk of thromboembolism, recurrent hemorrhage, and death after warfarin therapy interruption for gastrointestinal tract bleeding. (pp. 1484-91). Vol. 172. Archives of internal medicine. Published, 01/01/2013.
  • Simmons BJ, Jenner KM, Delate T, Clark NP, Kurz D & Witt DM (2012). Pilot study of a novel patient self-management program for warfarin therapy using venipuncture-acquired international normalized ratio monitoring. (pp. 1078-84). Vol. 32. Pharmacotherapy. Published, 12/01/2012.
  • Witt DM (2012). Approaches to optimal dosing of vitamin K antagonists. Seminars in thrombosis and hemostasis. Vol. 38, 667-72. Published, 10/01/2012.
  • Witt DM (2012). ACP Journal Club: rivaroxaban and usual care had similar rates of recurrent VTE and bleeding in symptomatic PE. (pp. JC2-6). Vol. 157. Annals of internal medicine. Published, 08/01/2012.
  • Dowd MB, Kippes KA, Witt DM, Delate T & Martinez K (2012). A randomized controlled trial of empiric warfarin dose reduction with the initiation of doxycycline therapy. Thrombosis research. Vol. 130, 152-6. Published, 07/01/2012.
  • Delate T, Witt DM, Ritzwoller D, Weeks JC, Kushi L, Hornbrook MC, Aiello Bowles EJ & Schrag D (2012). Outpatient use of low molecular weight heparin monotherapy for first-line treatment of venous thromboembolism in advanced cancer. The oncologist. Vol. 17, 419-27. Published, 04/01/2012.
  • Holbrook A, Schulman S, Witt DM, Vandvik PO, Fish J, Kovacs MJ, Svensson PJ, Veenstra DL, Crowther M, Guyatt GH & (2012). Evidence-based management of anticoagulant therapy: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. (pp. e152S-84S). Vol. 141. Chest. Published, 02/01/2012.
  • Olson KL, Holmes M, Dang C, Patel RJ & Witt DM (2011). Publication rates of abstracts presented by pharmacy residents at the Western States Conference. American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists. Vol. 69, 59-62. Published, 12/01/2011.
  • Witt DM (2011). Initiation and reinitiation of anticoagulation therapy. Seminars in hematology. Vol. 48, 295-301. Published, 10/01/2011.
  • Dentali F, Marchesi C, Giorgi Pierfranceschi M, Crowther M, Garcia D, Hylek E, Witt DM, Clark NP, Squizzato A, Imberti D & Ageno W (2011). Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis. Thrombosis and haemostasis. Vol. 106, 429-38. Published, 09/01/2011.
  • Herner SJ, Paulson DC, Delate T, Witt DM & Vondracek TG (2011). Evaluation of venous thromboembolism risk following hospitalization. (pp. 32-9). Vol. 32. Journal of thrombosis and thrombolysis. Published, 06/01/2011.
  • Dowd MB, Vavra KA, Witt DM, Delate T & Martinez K (2011). Empiric warfarin dose adjustment with prednisone therapy. A randomized, controlled trial. (pp. 472-7). Vol. 31. Journal of thrombosis and thrombolysis. Published, 05/01/2011.
  • Witt DM (2011). Quality measures and benchmarking for warfarin therapy. Journal of thrombosis and thrombolysis. Vol. 31, 242-8. Published, 03/01/2011.
  • Dentali F, Donadini MP, Clark N, Crowther MA, Garcia D, Hylek E, Witt DM, Ageno W & (2011). Brand name versus generic warfarin: a systematic review of the literature. Pharmacotherapy. Vol. 31, 386-93. Published, 03/01/2011.
  • Witt DM (2011). ACP Journal Club. Review: Positive D-dimer results predict recurrence after first unprovoked VTE regardless of test timing or cutpoint, or patient age. Annals of internal medicine. Vol. 154, JC1-4, JC1-5. Published, 01/01/2011.
  • Witt DM (2011). ACP Journal Club. Weekly INR self-testing did not reduce stroke, major bleeding, or death more than monthly clinic testing. (pp. JC1-4, JC1-5). Vol. 154. Annals of internal medicine. Published, 01/01/2011.
  • Witt DM (2010). Optimizing use of current anticoagulants. Hematology/oncology clinics of North America. Vol. 24, 717-26, viii. Published, 07/01/2010.
  • Crowther MA, Garcia D, Ageno W, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Schulman S, Kovacs M, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB & Kearon C (2010). Oral vitamin K effectively treats international normalised ratio (INR) values in excess of 10. Results of a prospective cohort study. Thrombosis and haemostasis. Vol. 104, 118-21. Published, 07/01/2010.
  • Witt DM, Delate T, Clark NP, Martell C, Tran T, Crowther MA, Garcia DA, Ageno W, Hylek EM & (2010). Twelve-month outcomes and predictors of very stable INR control in prevalent warfarin users. Journal of thrombosis and haemostasis : JTH. Vol. 8, 744-9. Published, 04/01/2010.
  • Clark NP, Delate T, Cleary SJ & Witt DM (2010). Analysis of unfractionated heparin dose requirements to target therapeutic anti-Xa intensity during pregnancy. Thrombosis research. Vol. 125, 402-5. Published, 04/01/2010.
  • Olson KL, Delate T, Johnson SG, Wilson ED & Witt DM (2010). Incidence of hemorrhage among anticoagulated patients receiving antiplatelet therapy after percutaneous coronary intervention. (pp. 316-21). Vol. 29. Journal of thrombosis and thrombolysis. Published, 03/01/2010.
  • Clark NP, Delate T, Cleary SJ & Witt DM (2010). Unfractionated heparin dose requirements targeting intermediate intensity antifactor Xa concentration during pregnancy. Pharmacotherapy. Vol. 30, 369-74. Published, 03/01/2010.
  • Witt DM, Delate T, McCool KH, Dowd MB, Clark NP, Crowther MA, Garcia DA, Ageno W, Dentali F, Hylek EM, Rector WG & (2009). Incidence and predictors of bleeding or thrombosis after polypectomy in patients receiving and not receiving anticoagulation therapy. Journal of thrombosis and haemostasis : JTH. Vol. 7, 1982-9. Published, 12/01/2009.
  • Witt DM, Delate T, Clark NP, Martell C, Tran T, Crowther MA, Garcia DA, Ageno W, Hylek EM & Ageno W (2009). Outcomes and predictors of very stable INR control during chronic anticoagulation therapy. Blood. Vol. 114, 952-6. Published, 07/01/2009.
  • Hill RR, Martinez KD, Delate T & Witt DM (2009). A descriptive evaluation of warfarin use in patients receiving hospice or palliative care services. Journal of thrombosis and thrombolysis. Vol. 27, 334-9. Published, 04/01/2009.
  • Clark NP, Delate T, Witt DM, Parker S & McDuffie R (2009). A descriptive evaluation of unfractionated heparin use during pregnancy. Journal of thrombosis and thrombolysis. Vol. 27, 267-73. Published, 04/01/2009.
  • Crowther MA, Ageno W, Garcia D, Wang L, Witt DM, Clark NP, Blostein MD, Kahn SR, Vesely SK, Schulman S, Kovacs MJ, Rodger MA, Wells P, Anderson D, Ginsberg J, Selby R, Siragusa S, Silingardi M, Dowd MB & Kearon C (2009). Oral vitamin K versus placebo to correct excessive anticoagulation in patients receiving warfarin: a randomized trial. Annals of internal medicine. Vol. 150, 293-300. Published, 03/01/2009.
  • Witt DM (2008). The Kaiser Permanente Colorado Clinical Pharmacy Anticoagulation Service as a model of modern anticoagulant care. Thrombosis research. Vol. 123 Suppl 1, S36-41. Published, 11/01/2008.
  • Garcia DA, Witt DM, Hylek E, Wittkowsky AK, Nutescu EA, Jacobson A, Moll S, Merli GJ, Crowther M, Earl L, Becker RC, Oertel L, Jaffer A, Ansell JE & (2008). Delivery of optimized anticoagulant therapy: consensus statement from the Anticoagulation Forum. The Annals of pharmacotherapy. Vol. 42, 979-88. Published, 08/01/2008.
  • Clark NP, Witt DM, Delate T, Trapp M, Garcia D, Ageno W, Hylek EM, Crowther MA & (2008). Thromboembolic consequences of subtherapeutic anticoagulation in patients stabilized on warfarin therapy: the low INR study. Pharmacotherapy. Vol. 28, 960-7. Published, 07/01/2008.
  • Johnson SG, Rogers K, Delate T & Witt DM (2008). Outcomes associated with combined antiplatelet and anticoagulant therapy. Chest. Vol. 133, 948-54. Published, 04/01/2008.
  • Johnson SG, Witt DM, Eddy TR & Delate T (2007). Warfarin and antiplatelet combination use among commercially insured patients enrolled in an anticoagulation management service. Chest. Vol. 131, 1500-7. Published, 05/01/2007.
  • Delate T, Witt DM, Jones JR, Bhardwaja B & Senser M (2007). Falsely elevated international normalized ratio values in patients undergoing anticoagulation therapy: a descriptive evaluation. Chest. Vol. 131, 816-22. Published, 03/01/2007.
  • Witt DM & Siragusa S (2007). Review: long term anticoagulation reduces recurrent venous thromboembolism. (pp. 45). Vol. 11. Evidence-based medicine. Published, 01/01/2007.
  • Witt DM & Siragusa S (2006). Review: Long-term anticoagulation reduces recurrent venous thromboembolism. (pp. 33). Vol. 144. ACP journal club. Published, 03/01/2006.
  • Anich KV, Witt DM, Delate T, Shanahan RL & Patel RJ (2005). A descriptive evaluation of routine complete blood count monitoring in patients receiving anticoagulation therapy. (pp. 183-8). Vol. 20. Journal of thrombosis and thrombolysis. Published, 11/01/2005.
  • Raebel MA, Witt DM, Carroll NM & Magid DJ (2005). Warfarin monitoring in ambulatory older individuals receiving antimicrobial therapy. Pharmacotherapy. Vol. 25, 1055-61. Published, 10/01/2005.
  • Johnson SG, Witt DM, Delate T & Sadler MA (2005). An examination of the association between therapeutic anticoagulation control and glycemic control for patients with diabetes on oral anticoagulation therapy. Journal of thrombosis and thrombolysis. Vol. 19, 209-12. Published, 08/01/2005.
  • Witt DM, Sadler MA, Shanahan RL, Mazzoli G & Tillman DJ (2005). Effect of a centralized clinical pharmacy anticoagulation service on the outcomes of anticoagulation therapy. (pp. 1515-22). Vol. 127. Chest. Published, 05/01/2005.
  • Chuang J, Sadler MA & Witt DM (2004). Impact of evacuated collection tube fill volume and mixing on routine coagulation testing using 2.5-ml (pediatric) tubes. (pp. 1262-6). Vol. 126. Chest. Published, 10/01/2004.
  • Witt DM & Humphries TL (2003). A retrospective evaluation of the management of excessive anticoagulation in an established clinical pharmacy anticoagulation service compared to traditional care. (pp. 113-8). Vol. 15. Journal of thrombosis and thrombolysis. Published, 11/01/2003.
  • Witt DM, Tillman DJ, Evans CM, Plotkin TV & Sadler MA (2003). Evaluation of the clinical and economic impact of a brand name-to-generic warfarin sodium conversion program. Pharmacotherapy. Vol. 23, 360-8. Published, 03/01/2003.
  • Patel RJ, Witt DM, Saseen JJ, Tillman DJ & Wilkinson DS (2001). Randomized, placebo-controlled trial of oral phytonadione for excessive anticoagulation. (pp. 1159-66). Vol. 20. Pharmacotherapy. Published, 01/01/2001.
  • Tillman DJ, Charland SL & Witt DM (2000). Effectiveness and economic impact associated with a program for outpatient management of acute deep vein thrombosis in a group model health maintenance organization. Archives of internal medicine. Vol. 160, 2926-32. Published, 11/01/2000.
  • Witt DM & Tillman DJ (1998). Clinical pharmacy anticoagulation services in a group model health maintenance organization. Pharmacy practice management quarterly. Vol. 18, 34-55. Published, 10/01/1998.
  • Lousberg TR, Witt DM, Beall DG, Carter BL & Malone DC (1998). Evaluation of excessive anticoagulation in a group model health maintenance organization. Archives of internal medicine. Vol. 158, 528-34. Published, 03/01/1998.
  • Witt DM & Lousberg TR (1997). Controversies surrounding estrogen use in postmenopausal women. The Annals of pharmacotherapy. Vol. 31, 745-55. Published, 07/01/1997.
  • Witt DM & Anderson L (1996). Dornase alfa: a new option in the management of cystic fibrosis. (pp. 40-8). Vol. 16. Pharmacotherapy. Published, 09/01/1996.
  • Kradjan WA, Witt DM, Opheim KE & Wood FC (1995). Lack of interaction between glipizide and co-trimoxazole. (pp. 997-1002). Vol. 34. Journal of clinical pharmacology. Published, 03/01/1995.
  • Witt DM, Ellsworth AJ & Leversee JH (1994). Amiodarone-clonazepam interaction. (pp. 1463-4). Vol. 27. The Annals of pharmacotherapy. Published, 03/01/1994.