Presentations

• "Environmental adaptation during fungal brain dissemination." Mycological Society of America, Annual Meeting, Flagstaff, AZ, USA . Contributed Talk, Presented, 08/02/2023.
• "Exploiting synergistic and antagonistic drug interactions to improve treatment of systemic fungal infections." Fungal Genetics Conferences, Genetics Society of America, Pacific Grove, CA. Invited Talk/Keynote, Presented, 03/18/2022.
• "From drugs to dissemination: biology and treatment of systemic fungal infections." Microbiology, Immunology, and Cancer Program, University of Minnesota, MN. Invited Talk/Keynote, Presented, 09/2021.

Research Groups

• Iman Ellahie, Undergraduate Student. 01/01/2024 - present.

Publications

• Hilbert ZA, Bednarek JM & Schwiesow MJW (2023). Distinct pathways of adaptive evolution in Cryptococcus neoformans reveal a mutation in adenylyl cyclase with trade-offs for pathogenicity. Current biology : CB. Vol. 33, 41364149.e94136-4149.e9. Published, 10/01/2023.
• Denham ST, Brammer B, Chung KY & Wambaugh MA (2022). A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans. Cell host & microbe. Vol. 30, 13821400.e81382-1400.e8. Published, 10/01/2022.
• Chung KY (2022). Biology and function of exo-polysaccharides from human fungal pathogens. Current clinical microbiology reports. Vol. 7, 1111-11. Published, 04/01/2022.
• Denham ST (2020). How Environmental Fungi Cause a Range of Clinical Outcomes in Susceptible Hosts. Journal of molecular biology. Vol. 431, 298230092982-3009. Published, 06/01/2020.
• Enioutina EY, Teng L, Fateeva TV & Brown JCS (2017). Phytotherapy as an alternative to conventional antimicrobials: combating microbial resistance. Expert review of clinical pharmacology. Vol. 10, 120312141203-1214. Published, 11/01/2017.
• Brown JCS, Nelson J, VanderSluis B, Deshpande R & Butts A (2015). Unraveling the biology of a fungal meningitis pathogen using chemical genetics. Cell. Vol. 159, 116811871168-1187. Published, 03/01/2015.
• Jarosz DF & Lancaster AK (2015). An evolutionarily conserved prion-like element converts wild fungi from metabolic specialists to generalists. Cell. Vol. 158, 107210821072-1082. Published, 01/01/2015.
• Jarosz DF, Brown JCS, Walker GA, Datta MS, Ung WL & Lancaster AK (2015). Cross-kingdom chemical communication drives a heritable, mutually beneficial prion-based transformation of metabolism. Cell. Vol. 158, 108310931083-1093. Published, 01/01/2015.
• Brown JC (2013). Approaching the functional annotation of fungal virulence factors using cross-species genetic interaction profiling. PLoS genetics. Vol. 8, e1003168e1003168. Published, 05/01/2013.
• Chun CD (2011). A major role for capsule-independent phagocytosis-inhibitory mechanisms in mammalian infection by Cryptococcus neoformans. Cell host & microbe. Vol. 9, 243251243-251. Published, 07/01/2011.
• Brown JC (2009). A heritable switch in carbon source utilization driven by an unusual yeast prion. Genes & development. Vol. 23, 232023322320-32. Published, 10/01/2009.