TARA Lynn DEANS portrait
  • Adjunct Associate Professor, Molecular Pharmaceutics
  • Adjunct Associate Professor, Biomedical Engineering
801-585-7859

Publications

  • Cabrera A, Edelstein HI, Glykofrydis F, Love KS, Palacios S, Tycko J, Zhang M, Lensch S, Shields CE, Livingston M, Weiss R, Zhao H & Haynes KA (2022). The sound of silence: Transgene silencing in mammalian cell engineering. Cell systems. Vol. 13, 950973950-973. Published, 12/01/2022.
  • Javdan SB (2022). Design and development of engineered receptors for cell and tissue engineering. Current opinion in systems biology. Vol. 28. Published, 12/01/2022.
  • Javdan SB (2021). Design and development of engineered receptors for cell and tissue engineering. Current opinion in systems biology. Vol. 28. Published, 09/01/2021.
  • Bush LM & Healy CP (2021). Biological Cells as Therapeutic Delivery Vehicles. Trends in pharmacological sciences. Vol. 42, 106118106-118. Published, 08/01/2021.
  • Bush LM & Healy CP (2021). Biological Cells as Therapeutic Delivery Vehicles. Trends in pharmacological sciences. Vol. 42, 106-118. Published, 08/01/2021.
  • Persson KM & Kneller PV (2021). High-Throughput Production of Platelet-Like Particles. Methods in molecular biology (Clifton, N.J.). Vol. 2258, 273283273-283. Published, 03/01/2021.
  • Persson KM & Kneller PV (2021). High-Throughput Production of Platelet-Like Particles. Methods in molecular biology (Clifton, N.J.). Vol. 2258, 273-283. Published, 03/01/2021.
  • Bowdish, D. & Desai, T.A., DePace, A., Haswell, E.S., Baltrus, D., Garcia, A.J., Deans, T., Lage, K., and Wittkopp, P. (2021). Leadership. Cell Syst. Published, 01/22/2021.
    https://doi.org/10.1016/j.cels.2020.12.004
  • Persson, K.M. & Kneller, P.V., Livingston, M.W., Bush, L.M., and Deans, T.L. (2020). High-Throughput Production of Platelet-Like Particles. Methods Mol Biol. Published, 12/20/2020.
    https://doi.org/10.1007/978-1-0716-1174-6_18
  • Davis, B & Backus, K., Winter, G., Chica, R., Li, D., Lee, S.Y., He, C., Week., A., Overall, C., Hagihara., S., Thuronyi, B., Kamat, S., Chen, L., Guerrero, R.H., Yao, S., Mahal, L.K., Voigt, C., Woo, C., Strauss, E., Kikuchi, K., Dore, T., Radform, S., Li, X.D., He (2020). Voices of chemical biology. Nature Chemical Biology. Published, 12/18/2020.
    https://doi.org/10.1038/s41589-020-00714-1
  • Fitzgerald, M. & Livingston, M. Gibbs, C. Deans, T. L. (2020). Rosa26 docking sites for investigating genetic circuit silencing in stem cells. Synth Biol (Oxf). Published, 11/17/2020.
    https://doi.org/10.1093/ synbio/ysaa014
  • Adam Vogel (2019). Synthetic biology for improving cell fate decisions and tissue engineering outcomes. Emerging Topics in Life Sciences. Published, 11/2019.
    https://doi.org/10.1042/ETLS20190091
  • Bush, L.M. & Gibbs, C., and Deans, T.L. (2019). Synthetic biology: paving the way with novel drug delivery. The Biochemist. Published, 06/01/2019.
    https://doi.org/10.1042/BIO04103024
  • Connor Healy & Tara L. Deans (2019). Genetic circuits to engineer tissues with alternative functions. Journal of Biological Engineering. Published, 05/2019.
  • Lucas Bush, Connor P. Healy, James J Marvin & Tara L. Deans (2018). Combination image flow cytometry for single-cell analysis reveals novel methods for isolating subsets of megakaryocyte progenitor populations. BioRxiv. Published, 12/2018.
    https://www.biorxiv.org/content/10.1101/512442v2
  • Michael Fitzgerald, Chelsea Gibbs & Tara L. Deans (2018). Rosa26 docking sites for investigating genetic circuit stability in stem cells. BioRxiv. Published, 12/2018.
  • Mitchell S. Weisenberger & Tara L. Deans (2018). Bottom-up approaches in synthetic biology and biomaterials for tissue engineering applications. J Ind Microbiol Biotechnol. Published, 12/2018.
  • Michael Fitzgerald, Chelsea Gibbs & Tara L. Deans (2017). Adoption of the Q Transcriptional System for Regulating Gene Expression in Stem Cells. ACS Synth Biol. Published, 08/2017.
  • MacDonald IC, Deans TL. Tools and applications in synthetic biology. Adv Drug Deliv Rev 2016; 105(Pt A): 20-34. Published, 10/03/2016.
  • Deans TL, Grainger DW, Fussenegger M. Synthetic Biology: Innovative approaches for pharmaceutics and drug delivery. Adv Drug Deliv Rev 2016; 105(Pt A): 1-2. Published, 10/02/2016.
  • Lam A & Deans TL (2015). A noisy tug of war: the battle between transcript production and degradation in the liver. (pp. 3-4). Vol. 33. Developmental cell. Published, 04/01/2015.
  • Deans, Tara L. (2014). Parallel Networks: Synthetic Biology and Artificial Intelligence. Association for Computing Machinery (ACM). Vol. 11(3), 1-22. Published, 12/2014.
    http://dx.doi.org/10.1145/2667229
  • Singh, A. & Deans, T. L. Elisseeff, J. H. (2013). Photomodulation of Cellular Gene Expression in Hydrogels. ACS Macro Letters. Published, 03/08/2013.
    https://doi.org/10.1021/mz300591m
  • Deans TL, Singh A, Gibson M & Elisseeff JH (2012). Regulating synthetic gene networks in 3D materials. Proceedings of the National Academy of Sciences of the United States of America. Vol. 109, 15217-22. Published, 09/01/2012.
  • Deans TL & Elisseeff JH (2010). The life of a cell: probing the complex relationships with the world. (pp. 499-501). Vol. 6. Cell stem cell. Published, 06/01/2010.
  • Deans TL & Elisseeff JH (2009). Stem cells in musculoskeletal engineered tissue. Current opinion in biotechnology. Vol. 20, 537-44. Published, 11/01/2009.
  • Deans TL, Cantor CR & Collins JJ (2007). A tunable genetic switch based on RNAi and repressor proteins for regulating gene expression in mammalian cells. Cell. Vol. 130, 363-72. Published, 07/01/2007.

Research Keywords

  • synthetic biology, stem cells, genetic engineering, genome engineering, hematopoiesis

Presentations

  • University of Pennsylvania, Center for targeted therapeutics and translational nano medicine (CT3N). “Using synthetic biology to engineering therapeutic devices”. Invited Talk/Keynote, Presented, 03/30/2021.
  • STEM World II “Ethics of Bioengineering: Genetic and Genome Engineering”. Invited Talk/Keynote, Presented, 03/28/2021.
  • University of California San Francisco, HIVE/Bioengineering and Therapeutic Sciences. “Engineering cell therapies using synthetic biology”. Invited Talk/Keynote, Presented, 02/28/2021.
  • Keystone Symposia on molecular and cellular biology. Emerging cell therapies: realizing the vision of next generation cell therapeutics, “Synthetic biology tools for the development of engineered stem cell therapeutics”. Invited Talk/Keynote, Presented, 01/26/2021.
  • International Conference on Biomedical Engineering (ICBE), “Using synthetic biology to improve cell therapies”. Invited Talk/Keynote, Presented, 01/09/2021.
  • Dixie State University, The Dixie Forum, “Using synthetic biology to engineer therapeutic devices”. Invited Talk/Keynote, Presented, 11/17/2020.
  • Rice University, Department of Bioengineering department seminar. “Using synthetic biology to engineer therapeutic devices.”. Invited Talk/Keynote, Presented, 10/13/2020.
  • University of North Carolina, The Division of Pharmacoengineering and Molecular Pharmaceutics, Rising Stars in Drug Delivery and Novel Carriers Webinar Series. “Using synthetic biology to engineer therapeutic devices”. Invited Talk/Keynote, Presented, 10/12/2020.
  • Northeastern University, Department of Bioengineering department seminar. “Using synthetic biology to engineer therapeutic devices.”. Invited Talk/Keynote, Presented, 09/30/2020.
  • Pre-tenure Bioengineering Faculty e-Seminar Series, “Using synthetic biology to engineer therapeutic devices”. Invited Talk/Keynote, Presented, 07/17/2020.
  • University of Pennsylvania, Philadelphia, PA “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 02/2020.
  • Utah State University, Logan, UT “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 02/2020.
  • Boston University, Boston, MA “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 02/2020.
  • Cell Press, Cambridge, MA “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 02/2020.
  • Huntsman Cancer Institute, Salt Lake City, UT “Synthetic Biology in medicine” . Invited Talk/Keynote, Presented, 01/2020.
  • Dept. Pharmaceutics & Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 01/2020.
  • International Research Collaborative Network, University of Pennsylvania, Philadelphia, PA “Overview of synthetic biology.” . Invited Talk/Keynote, Presented, 01/2020.
  • OSHER Lecture, University of Utah, Salt Lake City, UT “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 01/2020.
  • Carnegie Mellon University, Pittsburg, PA Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 01/2020.
  • 7th International Conference on Stem Cell Engineering, Barcelona, Spain “Engineering stem cells to create novel delivery vehicles” . Invited Talk/Keynote, Presented, 12/2019.
  • SYNGEN Series, London, England “Engineering cells to function as novel delivery vehicles” . Invited Talk/Keynote, Presented, 11/2019.
  • Office of Naval Research, Washington, DC “Engineering multifunctional blood products with synthetic biology” . Invited Talk/Keynote, Presented, 07/2019.
  • Gordon Research Conference, Synthetic Biology, Waterville Valley, NH “Engineering cells to function as novel delivery vehicles” . Invited Talk/Keynote, Presented, 07/2019.
  • SYNGEN Series, Boston, MA “Engineering cells to function as novel delivery devices” . Invited Talk/Keynote, Presented, 05/2019.
  • Materials Research Society, Phoenix, AZ “Bottom-up approaches for controlling cell behavior” . Invited Talk/Keynote, Presented, 04/2019.
  • Department Seminar, Dept. Molecular, Cell and Systems Biology, University of California Riverside, Riverside, CA “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 04/2019.
  • Department Seminar, Dept. Stem Cell Biology and Regenerative Medicine, Keck School of Medicine, Los Angeles, CA “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 01/2019.
  • International Conference on Biomolecular Engineering (ICBE), Newport Beach, CA “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 01/2019.
  • International Conference on Biomolecular Engineering (ICBE), Newport Beach, CA “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 01/2019.
  • Synthetic Biology in Medicine. Industrial Synthetic Biology Congress. Munich, Germany. October 2018. Invited Talk/Keynote, Presented, 10/2018.
  • Industrial Synthetic Biology Congress, Munich, Germany “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 10/2018.
  • Synthetic Biology in Medicine. Department of Pharmaceutics & Pharmaceutical Chemistry. University of Utah. September 2018. Invited Talk/Keynote, Presented, 09/2018.
  • Department Seminar, Dept. Pharmaceutics & Pharmaceutical Chemistry, University of Utah, Salt Lake City, UT “Synthetic biology in medicine” . Invited Talk/Keynote, Presented, 09/2018.
  • Biomedical Engineering Approaches for Studying and Directing Hematopoiesis. Cold Spring Harbor Labs, New York. August 2018. Invited Talk/Keynote, Presented, 08/2018.
  • Engineering Multifunctional Blood Products with Synthetic Biology. Office of Naval Research. Washington DC. August 2018. Invited Talk/Keynote, Presented, 08/2018.
  • Biomedical Engineering Approaches for Studying and Directing Hematopoiesis. Hematology Retreat, University of Utah. June 2018. Invited Talk/Keynote, Presented, 06/2018.
  • Synthetic Biology in Medicine. Deans Office, College of Engineering, University of Utah. February 2018. Invited Talk/Keynote, Presented, 02/2018.
  • Biomedical engineering approaches for studying and directing hematopoiesis. Department of Mathematics, University of Utah. February 2018. Invited Talk/Keynote, Presented, 02/2018.
  • Experimental synthetic biology: from concept to application. Invited Talk/Keynote, Presented, 10/12/2015.
  • Applications in synthetic biology: new approaches for treating and understanding human disease. Invited Talk/Keynote, Presented, 04/15/2015.

Research Groups

  • Mitchell Lewis, Graduate Student. BME. 08/15/2022 - present.
  • Farhana Islam, Graduate Student. BME. 08/15/2022 - present.
  • Acramul Haque Kabir, Graduate Student. BME. 01/2022 - 08/2026.
  • Travis Seamons, Graduate Student. BME. 08/16/2021 - 08/2022.
  • Emily Jepsen, Graduate Student. Biomedical Engineering. 08/2020 - 05/2022.
  • Mahima Choudhury, Graduate Student. 01/01/2020 - present.
  • Connor Healy, Graduate Student. BME. 08/13/2018 - 08/16/2021.
  • Cody MacDonald, Graduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Pauline Kneller, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Adam Vogel, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Travis Seamons, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Jenna Langford, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018. Awards/Scholarships/Stipends: UROP.
  • Kylie Persson, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Ellie Hanson, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Chelsea Gibbs, Undergraduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018. Awards/Scholarships/Stipends: Glenn E. Nielson Memorial Endowed Scholarship .
  • Connor Healy, Graduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018. Awards/Scholarships/Stipends: Kathy Phelps Equality Education Fund scholarship.
  • Lucas Bush, Graduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018. Awards/Scholarships/Stipends: NIH Hematology Training Grant.
  • Michael Fitzgerald, Graduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Mitch Weisenberger, Graduate Student. Biomedical Engineering. 01/01/2018 - 12/31/2018.
  • Chelsea Gibbs, Undergraduate Student. Bioengineering. 01/01/2016 - 12/31/2016. Awards/Scholarships/Stipends: UROP.
  • Chelsea Gibbs, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: Merrill Engineering Scholars Program.
  • Michael Fitzgerald, Graduate Student. Bioengineering. 01/01/2015 - 12/31/2015.
  • Cody MacDonald, Graduate Student. Bioengineering. 01/01/2015 - 12/31/2015.
  • Rebecca Goldstein, Graduate Student. Bioengineering. 01/01/2015 - 12/31/2015.
  • Tyler Page, Graduate Student. Bioengineering. 01/01/2015 - 12/31/2015.
  • Heidi Spears, Graduate Student. Bioengineering. 01/01/2015 - 12/31/2015.
  • Olivia Davidson, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: UROP.
  • Connor Healy, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: UROP.
  • Adrian Shimpi, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: Travel scholarship to attend national meeting to present his work.
  • Regan Stephenson, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: Scholarship to attend national conference to present her work.
  • Alec Lam, Undergraduate Student. Bioengineering. 01/01/2015 - 12/31/2015. Awards/Scholarships/Stipends: UROP.

Geographical Regions of Interest

  • Europe