Research Statement

Research Keywords

• Statistical Analysis
• Positron Emission Tomography (PET)
• Neuropsychiatry
• Neuroimaging
• Mood Disorders
• Magnetic Resonance Spectroscopy
• Magnetic Resonance Imaging
• Image Processing
• Functional MRI
• Drug Abuse and Dependence
• Diffusion Tensor Imaging
• Data Mining
• Anxiety Disorders

Grants, Contracts & Research Gifts

• Citicoline Treatment of Methamphetamine Dependence. PI: Perry Renshaw, M.D., Ph.D. 08/01/2009 - 07/31/2011. Total project budget to date: $0.00
• Longitudinal Neuroimaging of Metamphetamine-dependent Adolescents. PI: Perry Renshaw, M.D., Ph.D. NIH/NIDA , 07/01/2008 - 06/30/2013. Total project budget to date: $0.00
• MRI/MRSI Studies of Bipolar Treatment Response. PI: Perry Rensaw, M.D., Ph.D. NIH/NIDA, 07/01/2008 - 06/30/2010. Total project budget to date: $0.00
• MR Studies of Treatment-Induced Edema. PI: Perry Rensaw, M.D., Ph.D. GlaxoSmithKline, 08/01/2007 - 07/31/2008. Total project budget to date: $0.00
• INVEST Research Fellowship Award . PI: Young-Hoon Sung. NIH/NIDA, 08/01/2005 - 07/31/2007. Total project budget to date: $0.00
• Promising Investigator Grant Award. PI: Young-Hoon Sung. Korea Research Foundation, 08/01/2004 - 07/31/2005. Total project budget to date: $0.00

Languages

• English, fluent.
• Korean, fluent.

Publications

• Sung YH, Renshaw PF: Anatomical and Neurochemical Evidence of Neurotoxic Changes in Psychostimulant Abuse and Dependence. In B. Adinoff and E. A. Stein, Neuroimaging in Addiction (pp. 235-259) Wiley-Blackwell 2011. Published, 01/2012.
• Kondo DG, Sung YH, Hellem TL, Fiedler KK, Shi X, Jeong EK, Renshaw PF: Open-label adjunctive creatine for female adolescents with SSRI-resistant major depressive disorder: A 31-phosphorus magnetic resonance spectroscopy study. J Affect Disord. 2011 Dec;135(1-3):354-61. Published, 12/2011.
• Jeong EK, Sung YH, Kim SE, Zuo C, Shi X, Mellon EA, Renshaw PF: Measurement of creatine kinase reaction rate in human brain using magnetization transfer image-selected in vivo spectroscopy (MT-ISIS) and a volume 31P/1H radiofrequency coil in a clinical 3-T MRI system. NMR Biomed 2011: 24:765-70. Published, 08/2011.
• Park JK, Sung YH, Jeong SY, Lee JH: Higher Precontrast CT density of the carotid plaque in the symptomatic patients. Eur J Radiol. Epub 2011 Jul 2. Published, 07/2011.
• Kondo DG, Sung YH, Hellem TL, Delmastro KK, Jeong EK, Kim N, Shi X, Renshaw PF: Open-label uridine for treatment of depressed adolescents with bipolar disorder. J Child Adolesc Psychopharmacol. 2011;21(2):171-5. Published, 04/2011.
• Agarwal N, Sung YH, Jensen JE, daCunha G, Harper DG, Olson DP. Renshaw PF: Short-term administration of uridine increases brain membrane phospholipid precursors in healthy adults: a 31-phosphorus magnetic resonance spectroscopy study at 4T. Bipolar Disord 2010: 12(8):825-33. Published, 12/2010.
• Kondo DG, Hellem TL, Sung YH, Kim N, Jeong EK, Delmastro KK, Shi X, Renshaw PF: Review: magnetic resonance spectroscopy studies of pediatric major depressive disorder. Depress Res Treat. 2011: 650450. Published, 08/2010.
• Berlow YA, Wells WM, Ellison JM, Sung YH, Renshaw PF, Harper DG: Neuropsychiatric correlates of white matter hyperintensities in Alzheimer's disease. Int J Geriatr Psychiatry 2010: 25:780-788. Published, 08/2010.
• Yoon SJ, Lyoo IK, Kim HJ, Kim TS, Sung YH, Kim N, Lukas SE, Renshaw PF: Neurochemical alterations in methamphetamine-dependent patients treated with cytidine-5'-diphosphate choline: a longitudinal proton magnetic resonance spectroscopy study. Neuropsychopharmacology 2010: 35:1165-1173. Published, 04/2010.
• Han DH, Lyoo IK, Sung YH, Lee SH, Renshaw PF: The effect of acamprosate on alcohol and food craving in patients with alcohol dependence. Drug Alcohol Depend 2008: 93(3): 279-283. Published, 03/2008.
• Sung YH, Cho SC, Hwang J, Kim SJ, Kim H, Bae S, Kim N, Chang KH, Daniel M, Renshaw PF, Lyoo IK: Relationship between N-acetyl-aspartate in gray and white matter of abstinent methamphetamine abusers and the history of drug abuse. Drug Alcohol Depend 2007; 88(1):28-35. Published, 04/2007.
• Ham BJ, Sung YH, Kim N, Kim SJ, Kim JE, Kim DJ, Lee JY, Kim JH, Yoon SJ, Lyoo IK: Decreased GABA levels in anterior cingulate and basal ganglia in medicated subjects with panic disorder: A proton magnetic resonance spectroscopy (1H-MRS) study. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31:403-11. Published, 01/2007.
• Kim SJ, Lyoo IK, Hwang J, Chung A, Sung YH, Kim J, Kwon DH, Chang KH, Renshaw PF: Prefrontal grey-matter changes in short-term and long-term abstinent methamphetamine abusers. Int J Neuropsychopharmacol 2006; 9(2):221-8. Published, 04/2006.
• Hwang J, Lyoo IK, Kim SJ, Sung YH, Bae S, Cho SN, Lee HY, Lee DS, Renshaw PF: Decreased cerebral blood flow of the right anterior cingulate cortex in long-term and short-term abstinent methamphetamine users. Drug Alcohol Depend 2006; 82(2): 177-81. Published, 04/2006.
• Lyoo IK, Sung YH, Dager SR, Friedman SD, Lee JY, Kim SJ, Kim N, Dunner DL, Renshaw PF: Regional cerebral cortical thinning in bipolar disorder. Bipolar Disord 2006; 8(1):65-74. Published, 02/2006.
• Bae SC, Lyoo IK, Sung YH, Yoo J, Chung A, Yoon SJ, Kim DJ, Hwang J, Kim SJ, Renshaw PF: Increased white matter hyperintensities in male methamphetamine abusers. Drug Alcohol Depend 2006; 81(1):83-8. Published, 01/2006.
• Oh JS, Lyoo IK, Sung YH, Hwang J, Kim J, Chung A, Park KS, Kim SJ, Renshaw PF, Song IC: Shape changes of the corpus callosum in abstinent methamphetamine users. Neurosci Lett 2005; 384(1-2):76-81. Published, 08/2005.
• Kim SJ, Lyoo IK, Hwang J, Sung YH, Lee HY, Lee DS, Jeong DU, Renshaw PF: Frontal glucose hypometabolism in abstinent methamphetamine users. Neuropsychopharmacology 2005; 30(7):1383-91. Published, 07/2005.