Research Statement
Daniel R. Scoles, PhD is Associate Professor of Neurology. His scientific training includes biochemistry, genetics of natural populations, and neurology with emphasis on brain tumor research. Dr. Scoles’s research objectives are centered on the identification of drugs for the treatment of spinocerebellar ataxia type 2 (SCA2) and Parkinson’s disease. Drug discovery methodologies used by Dr. Scoles include quantitative high throughput screening (qHTS) and antisense oligonucleotide screening. His research is promoted by collaborative partnerships with industry and the National Institutes of Health (NCATS). Dr. Scoles also investigates molecular mechanisms of disease gene expression control aimed at identifying new therapeutic targets and understanding drug action. Dr. Scoles is currently supported by grants from the NINDS.
SPECIALTIES: Drug Discovery, Molecular Cellular and Organismal Biology.
Research Keywords
- Spinocerebellar Ataxias
- Parkinson's Disease