Our goal is to understand how cells maintain homeostasis and respond to stress in the endoplasmic reticulum (ER). As the entry point for the secretory pathway, the ER is fold and processes an enormous flux of proteins, yet maintains a strict quality control system to ensure that misfolded proteins do not move to the cell surface. We study the mechanisms of how cells respond to stress and what happens when misfolded and disease-related proteins disrupt the balance of folding in the ER.
- Bachelor of Arts, Biochemistry and Molecular Biology, REED COLLEGE
- Doctor of Philosophy, UNIVERSITY OF CALIFORNIA-BERKE