RYAN E LOOPER portrait
  • Associate Professor, Chemistry



  • B.S., Chemistry, Western Washington University
  • M.S., Chemistry, Western Wahington University. Project: Total synthesis of the heliannuols; allelopathic natural products.
  • Ph.D., Chemistry, Colorado State University. Project: Synthesis of the Cylindrospermopsin alkaloids.
  • Post-Doctoral Fellow, Chemical Biology, Harvard University

Honors & Awards

  • ACS Teva Pharmaceutical Scholar (2015). ACS, 08/17/2015
  • University of Utah Presidential Scholar. University of Utah , 07/2015
  • Entrepreneurial Faculty Scholar Award. University of Utah , 05/2014
  • Thieme Journals Award for Creative Research. Thieme Journals, 09/18/2011


12) Morgan J. Gainer, Nitasha R. Newbold, Yu Takahashi and Ryan E. Looper “Regioselective Rh(II)-catalyzed hydroaminations of propargylguanidines” Angew. Chem. Int. Ed. 2011, in press.

11) Robert L. Giles, Richard A. Nkansah and Ryan E. Looper "Synthesis of 2-thio and 2-oxoimidazoles via cascade addition-cycloisomerization reactions of propargyl cyanamides" J. Org. Chem. 2010, 75, 261-264.

10) Mohan R. Kaadige, Ryan E. Looper, Kamalanaadhan Sadhaasivam and Donald E. Ayer “Glutamine-dependent anapleurosis dictates glucose uptake and cell growth by regulating MondoA transcriptional activity" Proc. Nat. Acad. Sci. USA 2009, 106, 14878-14883.

9) Robert L. Giles, John D. Sullivan, Andrew M. Steiner and Ryan E. Looper “Addition-hydroamination reactions of propargyl cyanamides: Rapid access to highly substituted 2-aminoimidazole" Angew. Chem. Int. Ed. 2009, 48, 3116-3120.

8) John D. Sullivan, Robert L. Giles and Ryan E. Looper “2-aminoimidazoles from Leucetta sponges: synthesis and biology of an important pharmacophore" Curr. Bioactive Cmpds. 2009, 5, 39-78.

7) Ryan E. Looper, Daniela Pizzirani and Stuart L. Schreiber “Macrocycloadditions leading to conformationally restricted small molecules” Org. Lett. 2006, 8, 2063-2066.

6) Ryan E. Looper, Maria T.C. Runnegar and Robert M. Williams “Syntheses of the cylindrospermopsin alkaloids and their toxicological evaluation Tetrahedron 2006, 62, 4549–4562.

5) Ryan E. Looper, Maria T.C. Runnegar and Robert M. Williams “Synthesis of the putative structure of 7-deoxycylindrospermopsin: C7-oxygenation is not required for the inhibition of protein synthesis” Angew. Chem. Int. Ed. 2005, 44, 3879-3881.

4) Ryan E. Looper and Robert M. Williams “A concise asymmetric synthesis of the marine hepatotoxin 7-epi-cylindrospermopsin” Angew. Chem. Int. Ed. 2004, 43, 2930-2933.

3) James R. Vyvyan, Celeste Loitz, Ryan E. Looper, Cheryl S. Mattingly, Emily A. Peterson and Steven T. Staben “Synthesis of aromatic bisabolene natural products via palladium-catalyzed cross couplings of organozinc reagents” J. Org. Chem. 2004, 69, 2461-2468.

2) Ryan E. Looper and Robert M. Williams “Construction of cylindrospermopsin's A ring via an intramolecular oxazinone-N-oxide dipolar cycloaddition” Tetrahedron Lett. 2001, 42, 769-771.

1) James R. Vyvyan and Ryan E. Looper “Total synthesis of (±)-heliannuol D, an allelochemical from Helianthus annuusTetrahedron Lett. 2000, 41, 1151-1153.

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