Peter S Shen portrait
  • Assistant Professor, Department Of Biochemistry

Research Keywords

  • Cryogenic Electron Microscopy and Three-Dimensional Reconstruction (cryo-EM)
  • Structural Biology
  • Protein Quality Control

Presentations

  • Shen PS. Defying the Central Dogma by the Ribosome Quality Control Complex. Department of Chemistry and Biochemistry, Brigham Young University, Provo, UT. , , 2017.
  • Shen PS. Structural Basis of Protein Translocation by the Vps4 AAA ATPase. Department of Molecular, Cellular, and Developmental Biology, University of Colorado Boulder, Boulder, CO. , , 2017.
  • Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Co-translational quality control and mRNA-independent elongation of nascent chains. Medical Research Council, Laboratory of Molecular Biology, Cambridge, United Kingdom. , , 2015.
  • Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. mRNA-independent elongation of nascent chains by the Ribosome Quality Control Complex. Department of Biochemistry and Biophysics, Stockholm University, Stockholm, Sweden. , , 2015.
  • Shen PS, Domek MJ, Sanz-Garcia E, Makaju A, Taylor RM, Hoggan R, Culumber MD, Oberg CJ, Breakwell DP, Prince JT, Belnap DM. Conserved capsid structures between halophage CW02 and bacteriophage HK97. American Society for Microbiology Intermountain Branch Meeting, Weber State University, Ogden, UT. , , 2011.
  • Shen PS, *Sanz-Garcia E, *Belnap DM. Conformational variance of satellite tobacco mosaic virus capsid around a stable RNA scaffold. Federation of American Societies for Experimental Biology, Virus Assembly, Saxtons River, VT. , , 2010.
  • Shen PS, Enderlein D, Nelson CD, Carter WS, Kawano M, Xing L, Swenson RD, Olson NH, Baker TS, Cheng RH, Atwood WJ, Johne R, Belnap DM. The structure of avian polyomavirus reveals variably sized capsids and a putative location of the minor capsid protein VP4. American Society for Microbiology Intermountain Branch Meeting, Brigham Young University, Provo, UT. , , 2010.
  • Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Non-templated elongation of stalled nascent chains by the Ribosome Quality control Complex (RQC) [e-poster]. Poster session presented at Keystone Symposia Conference (Hybrid Methods in Structural Biology), Tahoe City, CA. Poster, Presented, 2015.
  • Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Rqc2p and 60S ribosomal subunits mediate mRNA-independent elongation of nascent chains. Poster session presented at Gordon Research Conference (3D Electron Microscopy), New London, NH. Poster, Presented, 2015.
  • Shen PS, Park J, Qin Y, Li X, Parsawar K, Larson MH, Cox J, Cheng Y, Lambowitz AM, Weissman JS, Brandman O, Frost A. Structure of a ribosome-bound, translational quality control complex. Poster session presented at Keystone Symposia Conference (Aging – Pushing the Limits of Cellular Quality Control), Steamboat Springs, CO. Poster, Presented, 2014.
  • Shen PS, Enderlein D, Nelson CD, Carter WS, Kawano M, Xing L, Swenson RD, Olson NH, Baker TS, Cheng RH, Atwood WJ, Johne R, Belnap DM. The structure of avian polyomavirus reveals variably sized capsids and a putative location of the minor capsid protein VP4. Poster session presented at Federation of American Societies for Experimental Biology Virus Assembly, Saxtons River, VT. Poster, Presented, 2010.
  • Shen PS, Enderlein D, Nelson CD, Carter WS, Kawano M, Xing L, Swenson RD, Olson NH, Baker TS, Cheng RH, Atwood WJ, Johne R, Belnap DM. Characterization of avian polyomavirus by means of sequence analysis, homology modeling, and cryogenic electron microscopy. Poster session presented at Annual Meeting of the American Society for Virology, University of British Columbia, Vancouver, BC, Canada. Poster, Presented, 2009.

Languages

  • English, Fluent.

Publications

  • Sinha NK, Iwasa J, Shen PS, Bass BL (date unknown). Dicer uses distinct modules for recognizing dsRNA termini. Accepted, .
  • Han H, Monroe N, Sundquist WI, Shen PS, Hill CP (date unknown). The AAA ATPase Vps4 binds ESCRT-III substrates through a repeating array of dipeptide-binding pockets. Accepted, .
  • Cooney I, Han H, Stewart MG, Carson RH, Hansen DT, Iwasa JH, Price JC, Hill CP, Shen PS (date unknown). Structure of the Cdc48 segregase in the act of unfolding an authentic substrate. Vol. 365, 502-505. Accepted, .
  • Han H, Fulcher JM, Dandey VP, Iwasa JH, Sundquist WI, Kay MS, Shen PS, Hill CP (date unknown). Structure of Vps4 with circular peptides and implications for translocation of two polypeptide chains by AAA+ ATPases. Accepted, .
  • Monroe N, Han H, Shen PS, Sundquist WI, Hill CP (date unknown). Structural basis of protein translocation by the Vps4-Vta1 AAA ATPase.LID - 10.7554/eLife.24487 [doi]LID - e24487 [pii]. Vol. 6. Accepted, .