Bruce Gale
  • Director, Nanofab
  • Adjunct Professor, Materials Science and Engineering
  • Adjunct Professor, Elect & Computer Engineering
  • Adjunct Professor, Bioengineering
  • Professor, Mechanical Engineering

Research Statement

I am primarily interested in biomedical applications of microfluidics. I have expertise in developing biosensors, microarrays, micropumps, and microneedles. We study manufacturing and design methods for these types of devices. I am interested in studying and developing micro- and nano- systems that have application in DNA, protein (proteomics), lipid, and cellular analysis as well as drug delivery, biowarfare agent detection, medical diagnostics, and drug discovery. I also have significant experience and expertise in nanoparticle separations using field flow fractionation.

Research Keywords

  • nanoparticle separations
  • microarrays
  • Proteins and Macromolecules
  • Nanotechnology
  • Nanoparticles
  • Microfluidics
  • Microelectromechanical Systems (MEMS)
  • Medical Device Engineering
  • High-Throughput Screening
  • Field Flow Fractionation
  • Drug Delivery Systems
  • DNA-protein interactions
  • Chemical Sensors
  • Biosensors
  • Bio-MEMS
  • Analytical Chemistry

Presentations

  • Jiyoung Son, Bruce K. Gale, James M. Hotaling and Douglas T. Carrell, “Purification Of Sperm From High WBC Semen Samples Using A Spiral Channel,” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 248-249, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • H. Feng, M. Hockin, S. Zhang, H. Sant and B. K. Gale, “Cell Lysis And Chromosome Extraction In Microfluidic Pinched Flow Devices,” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 689-690, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • R. Samuel, A. Jafek, J. Trauba, K. Carney, R. Pryor, B. Gale, C. Wittwer, and K. Aston, “40 Cycle PCR Using Human Genomic DNA In Less Than 1 Minute On A Microfluidic Chip” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 619-620, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • Susan Wojtalewicz, Brett Davis, Pratima Labroo, Ching-wen Li, Jill Shea, Bruce Gale, Himanshu Sant, Jay Agarwal, “Localized FK506 Delivery System for Peripheral Nerve Repair,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Pratima Labroo, Isak Goodwin, Brett Davis, Kyle Edwards, Scott Ho, Himanshu Sant, Bruce Gale, Jill Shea, Jay Agarwal, “Effect Of NGF Delivering Conduit On Peripheral Nerve Regeneration,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Pratima Labroo, Ching-wen Li, Himanshu Sant, Bruce Gale, Jill Shea, Jay Agarwal , “Self Contained Bioreactor For Bone Regeneration,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Farhad Shiri, Kevin E. Petersen, Bruce K. Gale, “EL-FFF Separation Of Nanoparticle Mixtures,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, P7. Other, Presented, 05/2016.
  • Kevin E. Petersen, Bruce K. Gale, Joshua L. Hood, Brody King, Farhad Shiri, Sam A. Wickline, “Separation Of Exosomes With Electrical Field Flow Fractionation,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, O22. Other, Presented, 05/2016.
  • Kevin E. Petersen, Brody King, Travis White, Farhad Shiri, Joshua L. Hood, Samuel A. Wickline, Bruce K. Gale, “Recent Advances In EL-SPLITT: A Flow Addition With Porous Electrode,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, P43. Other, Presented, 05/2016.
  • Bruce K. Gale and Kevin E. Petersen, “Exosome separation using electrical field flow fractionation and a new continuous SPLITT/FFF approach, in Proc. Of ACS 2016 Spring Meeting, March, 13, 2016, San Diego, CA, Paper ANYL 12, 2016. Invited Talk/Keynote, Presented, 03/13/2016.
  • Matt Hockin, Himanshu Jayant Sant, Mario Capecchi, Bruce K. Gale, “Dean flow fractionation of chromosomes,” in Proc. Of SPIE (Biomedical Optics), San Francisco, CA, February 13, 2016, paper 9705-1, 2016. Invited Talk/Keynote, Presented, 02/13/2016.
  • Pratima Labroo, Himanshu Sant, Scott Ho, Bruce Gale, Jill E. Shea and Jayant Agarwal, “Controlled Delivery of Growth Factors and Small Molecules for Peripheral Nerve Regeneration,” in Proc. Of AICHE, November 10, 2015, Salt Lake City, UT, Paper 437560, 2015. Conference Paper, Refereed, Presented, 11/10/2015.
  • Naveen Rathi, Nikki Davidoff, Ben Brooks, and Bruce K. Gale, “Using COMSOL to Simulate the Flow of Cells through a Continuous Flow Microfluidic Printing Device,” in Proc. Of NanoUtah 2015, October 15, 2015. Conference Paper, Refereed, Presented, 10/15/2015.
  • 1. Jesús Arellano, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury, and Bruce K. Gale, “Utilization of a Microfluidic Flow Cell Array in the Implementation of a High-Throughput Drug Screening and Cytotoxicity Evaluation System,” in Proc. of BMES 2015, Tampa, FL, October 7-10, 2015. Conference Paper, Refereed, Presented, 10/10/2015.
  • Matt Hockin, Himanshu Jayant Sant, Mario Capecchi, Bruce K. Gale, “An Inertial Microfluidic Device for Rapid Purification of Chromosomes,” in Proc. Of RGJ 2015, Pattaya, Thailand, June 5, 2015. Invited Talk/Keynote, Presented, 06/05/2015.
  • Y. R. Smith, H. Jayamohan, L. Hansen, S. K. Mohanty, B. K. Gale, and M. Misra, “Microfluidic Photocatalytic Device Utilizing Anodized Titania Nanotube Arrays: Application and Simulation Validation,” in Proc. Of ECS 2015 Spring Meeting, May 24-28, 2015, Chicago, IL, paper 1995, 2015. Conference Paper, Refereed, Presented, 05/28/2015.
  • R. C. Reid, S. D. Minteer, and B. K. Gale, “Contact Lens Biofuel Cell Tested in Conditions Similar to Human Eyes,” in Proc. Of ECS 2015 Spring Meeting, May 24-28, 2015, Chicago, IL, paper 1709, 2015. Conference Paper, Refereed, Presented, 05/28/2015.
  • Jiyoung Son, Raheel Samuel, Kristin Murphy, Douglas Carrell, Bruce Gale, and James Hotaling, “Non-Motile Sperm Cell Separation Using A Spiral Channel,” in Proc. Of Andrology Society of America, Poster #99, April 18-21, 2015, Salt Lake City, UT, 2015. Conference Paper, Refereed, Presented, 04/18/2015.
  • R Samuel, B Gale, O Badamjav, K Murphy, T Jenkins, D Carrell, J Hotaling, “Microfluidic Sperm Trapping Chip for Processing Samples with Low Concentration for Assisted Reproductive Technology (ART) Therapies,” in Proc. Of SLAS 2015, February 9-11, 2015, Washington DC, 2015. Conference Paper, Refereed, Presented, 02/11/2015.
  • Talk Presented at Colorado State University. Other, Presented, 11/09/2013.
  • Talk at Louisiana Tech University. Other, Other, 01/31/2013.
  • Bruce K. Gale, Microfluidic Tools for PCR and Digital PCR , at Digital PCR - Applications and Advances, October 15-16, 2012, San Diego, CA. Invited Talk/Keynote, Presented, 10/15/2012.
  • Bruce K. Gale, “A Microfluidic Toolbox for Biomedical Applications,” in Proc. of Royal Golden Jubilee-Ph.D. Congress XIII, Pattaya, Chonburi, Thailand, April 6 – 8, 2012, pg. 82. Invited Talk/Keynote, Presented, 04/06/2012.
  • Presentation to Myriad Genetics on DNA analysis techniques. Other, Presented, 09/2011.
  • Presentation to IPREM in Pau, France on Field Flow Fractionation. Other, Presented, 06/2011.
  • Presentation to SLCC Nanoscience Symposium. Other, Presented, 04/2011.
  • Bruce Gale, Himanshu Sant, Srinivas Merugu, and William Johnson, “Microfluidic field flow fractionation of SPLITT techniques for nanoparticles and protein characterization and separation,” in Proc. of the 2010 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, December 15-20, 2010, paper 47. Invited Talk/Keynote, Presented, 12/2010.
  • Bruce K. Gale, “A Microfluidic Toolbox for Biomedical Applications,” at the 54th International Conference on Electron, Ion, and Photon Beam Technology and Nanofabrication (EIPBN 2010), Anchorage, AK, June 4, 2010. Invited Talk/Keynote, Presented, 05/2010.
  • S.A. Molokhia, H.J. Sant, M.C. Hanson, R.M. Burr, A.E. Poursaid, C.J. Bishop, J.M. Simonis, B.K. Gale, B.K. Ambati, “New Intraocular Drug Delivery Device,” ARVO 2009 Annual Meeting Fort Lauderdale, FL May 3-7, 2009. Conference Paper, Refereed, Other, 05/03/2009.
  • Scott O. Sundberg, Bruce K. Gale, and Carl T Wittwer, “Spinning disk platform for digital PCR,” in Proc. of the 41st Annual Oak Ridge Conference, Baltimore, MD, April 16-17, 2009. Conference Paper, Refereed, Presented, 2009.
  • Jungkyu Kim, Michael Johnson, Parker Hill, Rahul Sonkul, Jongwon Kim, Bruce K. Gale, “Integrated microfluidic RNA extraction system” in Proc. of the 5th Conference on Microtechnologies in Medicine and Biology (MMB), Quebec City, Quebec, Canada 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, Adam Miles, and Bruce K. Gale, Improved Protein Microarrays Using Continuous Flow Printing And A Nanoporous Substrate,” in Proc. of MicroTAS 2009, Jeju, Korea, November 1-5, 2009, pg. 1781-1783. Conference Paper, Refereed, Other, 2009.
  • Himanshu J. Sant, Srinivas Merugu, and Bruce K. Gale, “A Microscale Diffusional SPLITT System: Macromolecule Separations,” in Proc. of 14th International Symposium on Field-and Flow-based Separation, Rio, Patras, Greece, July 5-9, 2009. Conference Paper, Refereed, Presented, 2009.
  • Srinivas Merugu, Himanshu J. Sant, and Bruce K. Gale, “Optimization of Cyclical Electrical Field Flow Fractionation,” in Proc. of 14th International Symposium on Field-and Flow-based Separation, Rio, Patras, Greece, July 5-9, 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, John Elsnab, Michael Johnson, Prabhu Arumugam, Hua Chen, Rahul Sonkul, Cory Shorr, Cody Gehrke, Bruce K. Gale, “A fully integrated nucleic acid identification system for bacteria monitoring,” in Proc. of NanoUtah 2009, October 15, 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, Rajesh Surapaneni, Bruce K. Gale :” Rapid prototyping of microfluidic systems using a PDMS/tape composite,” in Proc. of the 5th Conference on Microtechnologies in Medicine and Biology (MMB), Quebec City, Quebec, Canada 2009. Conference Paper, Refereed, Other, 2009.
  • Scott O. Sundberg, Carl Bruce K. Gale, and Carl T. Wittwer, “Spinning Disc Platform for Digital PCR,” Fourth Annual Mountain West Biomedical Engineering Conference, Park City, UT, September 5-6, 2008. Conference Paper, Presented, 09/06/2008.
  • Bruce K. Gale, “Printing of High Quality Protein and Lipid Microarrays Using a Continuous Flow Microspotter,” Joint 63rd Northwest / 21st Rocky Mountain Regional ACS Meeting, June 15-18, 2008. Conference Paper, Presented, 06/16/2008.
  • Mark A. Eddings, Adam Miles, Jianping Liu, David G. Myszka, Jennifer Shumaker-Parry, Josh W. Eckman, Gary Sams, Bruce K. Gale, “A Highly Parallel Flow Cell Enabling Multi-channel Sensing in Diagnostic Applications,” at Oak Ridge Conference (AACC), April 17-18, 2008. Invited Talk/Keynote, Presented, 04/18/2008.
  • Michael Johnson, Greg Liddiard, Mark Eddings, Bruce Gale, “Bubble Inclusion And Removal Using Pdms Membrane-Based Gas Permeation For Applications In Pumping And Mixing In Microfluidic Devices,” in Proc. of MicroTAS 2008, San Diego, CA, Oct. 12-16, 2008, pg. 1006-1008. Conference Paper, Other, 2008.
  • Scott O Sundberg, Bruce K. Gale, and Carl T. Wittwer, “Spinning Disc Platform for Digital PCR,” in Proc. of Association for Molecular Pathology 2008 Annual Meeting, October 29-November 2, 2008. Conference Paper, Other, 2008.

Research Groups

  • Harikrishnan Jayamohan, Postdoc. Mechanical Engineering. 07/01/2015 - 02/29/2016.
  • Christopher Lambert, Technician. 06/01/2014 - 08/15/2016.
  • Raheel Samuel, Postdoc. Mechanical Engineering/Andrology. 05/01/2014 - present.
  • Himanshu Sant, Research Professor. Mechanical Engineering. 07/01/2013 - present.
  • Wilaiwan Somchue, Visiting Student. 10/01/2010 - 05/15/2011.
  • Faris Ali, Technician. 09/01/2010 - 04/30/2011.
  • Julien Gigault, Visiting Student. 07/2010 - 10/15/2010.
  • Julian Soulacroix, Visiting Student. 05/01/2010 - 07/31/2010.
  • Merugu Srinivas, Postdoc. ECE. 10/01/2009 - 09/30/2010.
  • Himanshu Sant, Research Professor. BIoengineering. 09/2008 - present.

Research Equipment and Testing Expertise

  • Soft lithography, laser patterning, xurography, corona, rapid prototyping systems.

Geographical Regions of Interest

  • France
    Have established an exchange program and will be visiting this summer. Hosted two students from France in 2010. Spent 5 weeks working in Gaetane Lespes lab in Pau, France during June/July 2011.
  • Thailand
    Have had exchange student from Thailand working in my lab for 7 months and now have a joint publication. Will make a reciprocal visit in April 2012. Additional student arrived in November 2013. Finished in October 2014. Will visit again in June 2015.

Grants, Contracts & Research Gifts

  • Peripheral Nerve Regeneraion with a Novel Drug-Delivering Nerve Conduit. PI: Jayant Agarwal. Co-PI(s): Bruce Gale, Jill Shea, Bala Ambati. DOD CDMRP, 10/01/2013 - 09/30/2016. Total project budget to date: $600,000.00

Publications

  • Jesús Arellano, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury, and Bruce Gale, “Use of a highly parallel Microfluidic Flow Cell Array to determine therapeutic drug dose response curves,” Biomedical Microdevices, accepted. Accepted, 03/2017.
  • Li H, Gale B, Shea J, Sant H, Terry CM & Agarwal J (2017). Vascular Coupling System for End-to-End Anastomosis: An In Vivo Pilot Case Report. Cardiovascular engineering and technology. Vol. 8, 91-95. Published, 02/01/2017.
  • Harikrishnan Jayamohan, Valentin Romanov, Huizhong Li, Jiyoung Son, Raheel Samuel, John Nelson, and Bruce K. Gale, "Advances in Microfluidics and Lab-on-a-Chip Technologies" in Molecular Diagnostics, 3rd Edition.George P. Patrinos, Philip B. Danielson and Wilhelm J. Ansorge, Eds. Academic Press: New York, 2016. Published, 10/2016.
  • Labroo P, Ho S, Sant H, Shea J, Gale BK & Agarwal J (2016). Controlled Delivery of FK506 to Improve Nerve Regeneration. Shock (Augusta, Ga.). Vol. 46, 154-9. Published, 08/01/2016.
  • Labroo P, Shea J, Sant H, Gale B & Agarwal J (2016). Effect Of combining FK506 and neurotrophins on neurite branching and elongation. Muscle & nerve. Published, 08/01/2016.
  • Ragsdale V, Li H, Sant H, Ameel T & Gale BK (2016). A disposable, continuous-flow polymerase chain reaction device: design, fabrication and evaluation. Biomedical microdevices. Vol. 18, 62. Published, 07/01/2016.
  • Samuel R, Badamjav O, Murphy KE, Patel DP, Son J, Gale BK, Carrell DT & Hotaling JM (2016). Microfluidics: The future of microdissection TESE?. Systems biology in reproductive medicine. Vol. 62, 161-70. Published, 05/01/2016.
  • Harikrishnan Jayamohan, York Smith, Bruce K Gale, Swomitra K Mohanty, Manoranjan Misra, “Photocatalytic Microfluidic Reactors Utilizing Titania Nanotubes on Titanium Mesh for Degradation of Organic and Biological Contaminants,” Journal of Environmental Chemical Engineering, Vol. 4(1), 657-663.. Published, 04/30/2016.
  • Reid, Russell C., Jones, Sean R., Hickey, David P., Minteer, Shelley D., & Gale, Bruce K. (2016). Modeling Carbon Nanotube Connectivity and Surface Activity in a Contact Lens Biofuel Cell. Elsevier BV. Vol. 203, 30-40. Published, 04/2016.
  • Lin, Keng-Min, Shea, Jill, Gale, Bruce K, Sant, Himanshu, Larrabee, Patti, Agarwal, Jay (2016). Nerve growth factor released from a novel PLGA nerve conduit can improve axon growth. IOP Publishing. Vol. 26(4), 045016. Published, 04/2016.
  • Chen, Jiao, Zhao, Yi, Yan, Xiaohui, Zhang, Li, Choy, Kwongwai, Hu, Jun, Sant, Himanshu J., Gale, Bruce K., Tang, Tao & Deng, Yan (2016). Transdermal Delivery of siRNA through Microneedle Array. Nature Publishing Group. Vol. 6, 21422. Published, 02/2016.
  • Ornthai M, Siripinyanond A & Gale BK (2016). Effect of Ionic and Nonionic Carriers in Electrical Field-Flow Fractionation. Analytical chemistry. Vol. 88, 1794-803. Published, 02/01/2016.
  • Huizhong Li, Jay Agarwal, Brittany Coats, and Bruce K. Gale,Optimization and Evaluation of a Vascular Coupling Device for End-to-End Anastomosis: A Finite Element Analysis,” Journal of Medical Devices, Vol. 10, No. 3, pp. 011003(1-7), 2016. DOI: 10.1115/1.4031810. Published, 01/01/2016.
  • Ornthai M, Siripinyanond A & Gale BK (2016). Biased cyclical electrical field-flow fractionation for separation of submicron particles. Analytical and bioanalytical chemistry. Vol. 408, 855-63. Published, 01/01/2016.
  • Victoria Ragsdale, Huizhong Li, Tim Ameel, and Bruce Kent Gale, “Three-Dimensional Heat Transfer Analysis Of A Disposable, Continuous-Flow Polymerase Chain Reaction Device,” in Proc. Of MicroTAS 2015, October 25-29, 2015, Gyeongju, Korea, pp. 2038-2040, 2015. Published, 10/29/2015.
  • Jiyoung Son, Odgerel Badamjav, Timothy Gerald Jenkins, Bruce Kent Gale, James M Hotaling, and Douglas T Carrell “Active Higher Quality Sperm Separation Using A Spiral Channel,” in Proc. Of MicroTAS 2015, October 25-29, 2015, Gyeongju, Korea, pp. 367-369, 2015. Published, 10/29/2015.
  • Jesús Arellano, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury, and Bruce K. Gale, “Utilization of a Microfluidic Flow Cell Array in the Implementation of a High-Throughput Drug Screening and Cytotoxicity Evaluation System,” in Proc. of BMES 2015, Tampa, FL, October 7-10, 2015. Published, 10/07/2015.
  • T. Onur Tasci, William P. Johnson, Diego P Fernandez, Eliana Manangon , Bruce K. Gale, “Particle Based Modeling Of Electrical Field Flow Fractionation Systems,” Chromatography, Vol. 2, pp. 594-610, 2015, doi:10.3390/chromatography2040594. Published, 09/01/2015.
  • Jiyoung Son, Kristin Murphy, Raheel Samuel, Bruce K Gale, Douglas Carrell, Jim Hotaling, “Non-Motile Sperm Cell Separation Using A Spiral Channel, Anal. Meth., Vol. 7, pp. 8041 - 8047, 2015. DOI: 10.1039/C5AY02205C. Published, 08/02/2015.
  • Huizhong Li, Cody Gehrke, Bruce K. Gale, Himanshu Sant, Brittany Coats and Jay Agarwal, “A New Vascular Coupler Design for End-to-End Anastomosis: Fabrication and Proof-of-Concept Evaluation,” J. Med. Devices, Vol. 9, No. 3, pp. [031002], 2015. DOI: 10.1115/1.4029924. Published, 07/01/2015.
  • Lespes G, Contado C & Gale BK (2015). Field and flow-based separations. Analytical and bioanalytical chemistry. Vol. 407, 4299-300. Published, 05/01/2015.
  • Davidoff SN, Stallings KL, Brooks AE, Gale BK & Brooks BD (2015). Optimal tube length for the submerged printing of ovarian cancer cells. Biomedical sciences instrumentation. Vol. 51, 17-23. Published, 05/01/2015.
  • Jayamohan H, Gale BK, Minson B, Lambert CJ, Gordon N & Sant HJ (2015). Highly sensitive bacteria quantification using immunomagnetic separation and electrochemical detection of guanine-labeled secondary beads. Sensors (Basel, Switzerland). Vol. 15, 12034-52. Published, 05/01/2015.
  • Reid RC, Minteer SD & Gale BK (2015). Contact lens biofuel cell tested in a synthetic tear solution. Biosensors & bioelectronics. Vol. 68, 142-8. Published, 03/01/2015.
  • Samuel R, Stephenson R, Roy P, Pryor R, Zhou L, Bonkowsky JL & Gale BK (2015). Microfluidic-aided genotyping of zebrafish in the first 48 h with 100% viability. Biomedical microdevices. Vol. 17, 43. Published, 03/01/2015.
  • Huizhong Li, Bruce K. Gale, Himanshu Sant, Jill Shea, E. David Bell and Jay Agarwal, “A Novel Vascular Coupling System for End-to-End Anastomosis,” Cardiovascular Engineering and Technology, Vol. 6 (3), pp. 294-302, 2015. Published, 02/01/2015.
  • Russell Reid, Shelley D Minteer, Bruce K Gale, “Contact Lens Biofuel Cell Tested in a Synthetic Tear Solution,” Biosensors and Bioelectronics, Vol. 68, pp. 142-148, 2015. DOI: 10.1016/j.bios.2014.12.034. Published, 01/2015.
  • Kevin Petersen, Lucia Manangon, Joshua Hood, Samuel Wickline, Diego Fernandez, William Johnson, Bruce K. Gale, “A Review of Exosome Separation Techniques and Characterization of B16-F10 Mouse Melanoma Exosomes with AF4-UV-MALS-QELS-DLS-TEM,” Anal. Bioanal. Chem., Vol. 406 (30), pp. 7855-66, 2014. Published, 12/01/2014.
  • Jiyoung Son, Raheel Samuel, Kristin Murphy, Himanshu Sant, Matthew Hockin, Bruce K. Gale, James M. Hotaling, and Douglas T. Carrell, “Sperm Cell Separation Using A Spiral Channel,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2570-2571. Published, 10/28/2014.
  • T. Onur Tasci, Chris J. Lambert, Himanshu J. Sant, Eliana Manangon, Diego P. Fernandez, William P. Johnson, and Bruce K. Gale, “A Microfluidic System For High Throughput Continuous Separation Of Nanoparticles,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2444-2446. Published, 10/28/2014.
  • Matthew F. Hockin, Himanshu J. Sant, Mario R. Capecchi and Bruce K. Gale, “An inertial microfluidic device for rapid purification of native chromosomes,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2510-2511. Published, 10/21/2014.
  • Mathuros Ornthai, Bruce K. Gale, Juwadee Shiowatan and Atitaya Siripinyanond, “Biased Cyclical Electrical Field-Flow Fractionation for Separation of Submicron Particles,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. P8, 2014. Published, 10/14/2014.
  • Mathuros Ornthai, Kevin E. Petersen, Bruce K. Gale, Jiyoung Son, and Atitaya Siripinyanond, “Separation of Biological Particles: El-FFF and Spiral Channels,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. O33, 2014. Published, 10/14/2014.
  • Ian R. Harvey, Bruce Gale, Tom Parks, Richard Brown, Florian Solzbacher, “USTAR / U of U / COE Partnerships to Spur R&D in micro/nano Materials & Systems, in Proc. Of COMS 2014, Salt Lake City, UT, October 12-16, 2014. Published, 10/14/2014.
  • Matthew Hockin, Himanshu Sant, Kevin Petersen, Bruce Gale, “Separation of Chromosomes Using FFF and Inertial Microfluidics,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. O18, 2014. Published, 10/14/2014.
  • Kevin E. Petersen, Mathuros Ornthai, Joshua Hood, Sam Wickline, and Bruce K. Gale, “Electrical Field Flow Fractionation of Exosomes,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. P22, 2014. Published, 10/14/2014.
  • Jesús Arellano, James Gammon, Chieh-Hsiang Yang, Margit Janat-Amsbury, and Bruce K. Gale, “Development of Continuous Flow Microspotter (CFM) for High-Throughput Drug Screening and Cytotoxicity Evaluation,” in Proc. of BMES 2014, San Antonio, TX, October 22-25, 2014. Published, 10/01/2014.
  • Scott Ho, Pratima Labroo, Keng-Min Lin, Himanshu Sant, Jill Shea, Jay Agarwal, Bruce Gale, “Bioresorbable Multi-Drug Delivery Conduit to Promote Peripheral Nerve Regeneration,” in Proc. of BMES 2014, San Antonio, TX, October 22-25, 2014. Published, 10/01/2014.
  • Raheel Samuel, Colin M Thacker, A. Villu Maricq and Bruce K. Gale, “Simple and cost-effective fabrication of microvalve arrays in PDMS using laser cut molds with application to C. elegans manipulation in microfluidics,” Journal of Micromechanics and Microengineering, Vol. 24(10), pp. 105007 (8 pages), 2014. DOI: 10.1088/0960-1317/24/10/105007. Published, 10/01/2014.
  • Tonguc O. Tasci, William. P. Johnson, Diego. P. Fernandez, Eliana. Manangon, Bruce. K. Gale, “Circuit modification in electrical field flow fractionation systems generating higher resolution separation of nanoparticles,” J. Chromatography A, Vol. 1365, pp. 164–172, 2014. DOI: 10.1016/j.chroma.2014.08.097. Published, 09/01/2014.
  • Huizhong Li, Bruce Gale, Himanshu Sant, Jill Shea, and Jay Agarwal, “Design, Fabrication and Testing of A Novel End-to-End Vascular Coupling System,” in Proc. EMBC 2014, Chicago, IL, August 26-30, 2014. Published, 08/26/2014.
  • Bruce K. Gale, Raheel Samuel, Harikrishnan Jayamohan, and Himanshu Sant, “Microfluidic Devices for Rapid and Sensitive Identification of Organisms,” in Proc. EMBS 2014, Chicago, IL, August 28-31, 2014. Published, 08/01/2014.
  • Scott O. Sundberg, Carl T. Wittwer, Luming Zhou, Robert Palais, Zachary Dwight, and Bruce K. Gale, “Quasi-Digital PCR: Enrichment and Quantification of Rare DNA Variants,” Biomedical Microdevices, Vol. 16(4), pp. 639-644, August 2014. doi: 10.1007/s10544-014-9866-0. Published, 08/01/2014.
  • Valentin Romanov, S. Nikki Davidoff, Adam R. Miles, David W. Grainger, Bruce K. Gale, and Benjamin D. Brooks, “A Critical Comparison of Protein Microarray Fabrication Technologies,” Analyst, Vol. 139 (6), pp. 1303-1326, 2014. doi: 10.1039/c3an01577g. Published, 06/01/2014.
  • S. Nikki Davidoff, Adam R. Miles, Bruce K. Gale, Josh W. Eckman, and Benjamin D. Brooks, “The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter,” J. Vis. Exp. (86), e51273, 2014. doi:10.3791/51273. Published, 06/01/2014.
  • Davidoff SN, Miles AR, Romanov V, Gale BK, Eckman JW & Brooks BD (2014). The submerged printing of cells onto a modified surface using a continuous flow microspotter. Journal of visualized experiments : JoVE. Published, 05/01/2014.
  • R Samuel, R Stephenson, P Roy, R Pryor, L Zhou, J L Bonkowsky, B K Gale “Microfluidic methods for early-stage zebrafish embryo genotyping while maintaining embryo viability” 2014 International Conference on Zebrafish Development and Genetics, Madison, USA. Published, 05/01/2014.
  • Wei Chen, Chong Wang, Li Yan, Longbiao Huang, Xiaoyue Zhu, Bing Chen, Himanshu J Sant, Xinrui Niu, Val Roy, Bruce K Gale, Xianfeng Chen, “Improved polyvinylpyrrolidone microneedle arrays with non-stoichimetric cyclodextrin,” J. Mater. Chem. B, Vol. 2, pp. 1699-1705, 2014. Published, 04/2014.
  • Li Yan, Anthony P Raphael, Xiaoyue Zhu, Beilei Wang, Wei Chen, Tao Tang, Yan Deng, Himanshu J Sant, Guangyu Zhu, Kwong Wai Choy, Bruce K Gale, Tarl W Prow, Xianfeng Chen, “Nanocomposite strengthened dissolving microneedles for improved transdermal delivery to human skin.” Advanced Healthcare Materials,Vol.;3(4), pp. 555-564, April 2014.. DOI: 10.1002/adhm.201300312. Published, 04/2014.
  • Cody Gehrke, Huizhong Li, Himanshu Sant, Bruce Gale and Jay Agarwal, “Design, Fabrication and Testing of a Novel Vascular Coupling Device,” J. Biomed. Microdev., Vol. 16, pp. 173-180, 2014. Published, 01/2014.
  • Wei Chen, Chong Wang, Li Yan, Longbiao Huang, Xiaoyue Zhu, Bing Chen, Himanshu J Sant, Xinrui Niu, Val Roy, Bruce K Gale, Xianfeng Chen, “Improved polyvinylpyrrolidone microneedle arrays with non-stoichimetric cyclodextrin,” J. Mater. Chem. B, Vol. 2, pp. 1699-1705, 2014. In press, 12/2013.
  • Tonguc O. Tasci, William. P. Johnson, Diego. P. Fernandez, Eliana. Manangon, Bruce. K. Gale, “Biased Cyclical Electrical Field Flow Fractionation for Separation of Sub 50 nm Particles,” Anal. Chem., Vol. 85, No. 23, pp. 11225-11232, December 3, 2013. Published, 12/2013.
  • Harikrishnan Jayamohan, Swomitra Mohanty, Bruce K. Gale, “Platinum functionalized titania nanotube array sensor for detection of trichloroethylene in water,” in Proc. of IEEE-Sensors 2013, Baltimore, Maryland, 3-6 Nov. 2013. 10.1109/ICSENS.2013.6688608. Pending, 11/2013.
  • Huizhong Li, Cody Gehrke, Himanshu Sant, Bruce K. Gale, Jay Agarwal, “A novel arterial coupler for microvascular surgery,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Harikrishnan Jayamohan, York R. Smith, Bruce K. Gale, Manoranjan Misra, Swomitra K. Mohanty, “Platinum functionalized titania nanotube array sensor for detection of trichloroethylene in water,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Cady Lancaster, Aixiang Liu, Curtis Sudbury, Bruce K. Gale, Jennifer Shumaker-Parry, “Atomic layer deposition of Al2O3 on plasmonic nanostructures for surface chemistry and multiplex analysis,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Li Yan, Anthony P Raphael, Xiaoyue Zhu, Beilei Wang, Wei Chen, Tao Tang, Yan Deng, Himanshu J Sant, Guangyu Zhu, Kwong Wai Choy, Bruce K Gale, Tarl W Prow, Xianfeng Chen, “Nanocomposite strengthened dissolving microneedles for improved transdermal delivery to human skin.” Advanced Healthcare Materials, Published on the Web 30 Oct 2013. DOI: 10.1002/adhm.201300312. Released, 10/2013.
  • Huizhong Li, Harikrishnan Jayamohan, Christopher Lambert, Swomitra Mohanty and Bruce K. Gale, “Automated Whole Blood Processing With A Portable Microfluidic Device For Point-Of-Care Diagnosis,” in Proc. of MicroTAS 2013, Freiburg, Germany, October 27 –31, 2013, pp. 1758-1760. Published, 10/2013.
  • Russell C. Reid, Fabien Giroud, Shelley D. Minteer, Bruce K. Gale, “Enzymatic Biofuel Cell with a Flow-Through Toray Paper Bioanode for Improved Fuel Utilization,” J. Electrochem. Soc., Vol. 160, No. 9, pp. H612-H619, 2013. Published, 09/2013.
  • Huizhong Li, Cody Gehrke, Himanshu Sant, Bruce K. Gale, Jayant Agarwal, “An Implantable Vascular Coupling Device for End-to-End Anastomosis,” in Proc. of The BMES 2013 Annual Meeting, Seattle, Washington, USA, September, 2013. Published, 09/2013.
  • Keng-Min Lin, Bruce Gale, Himanshu Sant, Jill Shea, William Sanders, Christi Terry and Jay Agarwal. “BSA-Filled PLGA nerve conduits for potential applications in nerve regeneration,” in Proc. of The BMES 2013 Annual Meeting, Seattle, Washington, USA, September, 2013. Published, 09/2013.
  • Jungkyu Kim, John Elsnab, Cody Gehrke, Jun Li, Bruce K. Gale, “Microfluidic Integrated Multi-walled Carbon Nanotube (MWCNT) Sensor for Electrochemical Nucleic Acid Concentration Measurement,” Sens. Act. B: Chemical., Vol. 185, pp. 370-376, August 2013. Published, 08/2013.
  • Tonguc Onur Tasci, William. Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “Utilization of Biased Voltage Waveforms for High Resolution Cyclical Electrical Field Flow Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “External Electrical Circuits for High Resolution Cyclical Electrical Field Flow Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Bruce K. Gale, “Magnetic Field Flow Fractionation Using Linear Halbach Arrays,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Eliana Manangon, Diego. P. Fernandez, Bruce K. Gale, Tonguc Onur Tasci, William Paul Johnson, “Mass Recoveries in Nano- to Micro-Particle Analysis of Environmental Samples Via Flow Field Flow Fractionation-Inductively Coupled Plasma Mass Spectrometry,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “Computer Modeling of the Electrical Field Flow Fractionation Systems,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Himanshu J. Sant, Christopher J. Lambert, Eliana Manangon, Bruce K. Gale, “Continuous Separation of Nanoparticles by Cyclical Electrical Split Flow Thin Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Kevin E. Petersen, Eliana Manangon, Joshua L. Hood, Diego P. Fernandez, William P. Johnson, Bruce K. Gale, “Separation of Melanoma Exosomes and Microparticles with As-FlFFF,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • T. O. Tasci, C. J. Lambert, W. P. Johnson, B. K. Gale, "A Magnetic Particle Micromixer,” in Proc. of Frontiers in BioMagnetic Particles, Telluride, CO, USA, June 2-5, 2013. Published, 06/2013.
  • T. O. Tasci, W. P. Johnson, B. K. Gale, "Particle Based Model For A Cyclical Magnetic Field Flow Fractionation System,” in Proc. of Frontiers in BioMagnetic Particles, Telluride, CO, USA, June 2-5, 2013. Published, 06/2013.
  • G.T. Carling, X. Diaz, M. Ponce, L. Perez, L. Nasimba, E. Pazmino, A. Rudd, S. Merugu, D.P. Fernandez, B.K. Gale, W.P. Johnson, “Particulate and dissolved trace element concentrations in three southern Ecuador rivers impacted by artisanal gold mining,” Water, Air, and Soil Pollution, Vol. 224, No. 2, 2013. Published, 05/2013.
  • Valentin Romanov, Adam Miles, Bruce Gale, Josh Eckman, Benjamin Brooks, “Flow Printingfor Fluorescent Microarray Applications,” in Proc. of 50th Annual Rocky Mountain Bioengineering Symposium & 50th International ISA Biomedical Sciences Instrumentation Symposium 2013, Colorado Springs, Colorado, USA, 5-7 April 2013, pp. 118-124. Published, 04/2013.
  • Valentin Romanov, Bruce Gale, Josh Eckman, Adam Miles, Benjamin Brooks, “Spot Morphology In Protein Microarrays,” in Proc. of 50th Annual Rocky Mountain Bioengineering Symposium & 50th International ISA Biomedical Sciences Instrumentation Symposium 2013, Colorado Springs, Colorado, USA, 5-7 April 2013, pp. 25-32. Published, 04/2013.
  • Bruce K. Gale, “Spinning Disk Platform for Digital PCR,” at Molecular Med Tri-con 2013, February 11, 2013, San Francisco, CA. Published, 02/11/2013.
  • Nathan Gooch, Randon Michael Burr, Dolly J. Holt, Bruce Gale, and Balamurali Ambati, “Design and in Vitro Biocompatibility of a Novel Ocular Drug Delivery Device,” J. Funct. Biomater. Vol. 4(1), pp. 14-27, doi:10.3390/jfb4010014, 2013. Published, 01/2013.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, and B. K. Gale, “Separation of Magnetic Nanoparticles by Cyclical Electrical Field Flow Fractionation,” IEEE Trans. On Magnetics, Vol. 49, No. 1, pp. 331-335, 2013. Published, 01/2013.
  • Wilaiwan Somchue, Atitaya Siripinyanond, and Bruce K. Gale, “Cyclical Electrical Field-Flow Fractionation for Metal Nanoparticles Characterization,” Electrophoresis, submitted. Submitted, 12/2012.
  • Harikrishnan Jayamohan, Himanshu Sant, York Smith, Swomitra K. Mohanty, Manoranjan Misra, Bruce K. Gale, “Ordered carbonized titania nanotube based electrochemical detection of hemoglobin,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 38. Published, 10/12/2012.
  • Kevin E. Petersen, Hyun-Tae Kim, Qingbo Guo, Hanseup Kim, Bruce Gale, “A valve-less electrostatic gas micropump with a peristaltic movement of a single zipper electrode,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 40. Published, 10/12/2012.
  • Russell Reid, Shelley Minteer, Fabien Giroud, Bruce Gale, “A flow-through microfluidic biofuel cell,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 44. Published, 10/12/2012.
  • Jesus Arellano, Chieh-Hsiang Yang Bruce K. Gale, Margit Janat-Amsbury, Spencer B. Bremer, Naveen Rathi, “Development of continuous flow microspotter for high-throughput drug screening and cytotoxicity evaluation,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 33. Published, 10/12/2012.
  • Lucia E. Manangon, Onur T. Tasci, Diego P. Fernandez, Bruce K. Gale, William P. Johnson, “Fractionation of size distributed samples by asymmetric flow field flow fractionation coupled online to light scattering and inductively coupled plasma mass spectrometry detectors,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 44. Published, 10/12/2012.
  • Li Yan, Anthony P Raphael, Beilei Wang, Guangyu Zhu, Wei Chen, Himanshu J Sant, Bruce K Gale, Tarl W Prow, Xianfeng Chen, “Nanocomposite strengthened dissolving microneedles for improved transdermal delivery to human skin.” Adv. Mat. Submitted. Submitted, 10/2012.
  • Keng-Min Lin, Himanshu J. Sant, Balamurali K. Ambati and Bruce K. Gale, “Intraocular Pressure Sensors: New Approaches For Real-Time Intraocular Pressure Measurement Using A Purely Microfluidic Chip,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • T. O. Tasci, C. J. Lambert, H. J. Sant, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Investigation Of The Channel Height On The Separation Efficiency Of An Electrical Field Flow Fractionation System,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • Raheel Samuel, Colin Thacker, Andres Villu Maricq, Bruce K. Gale, “Simple And Low-Cost Fabrication Protocol For Producing 100’s Of Pneumatic Microvalves In All-PDMS Substrates For Microfluidics Research,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • Keng-Min Lin, Himanshu J. Sant, Bruce K. Gale, and Jayant P. Agarwal, “New Approaches to Bridge Nerve Gaps: Development of a Novel Drug-Delivering Nerve Conduit,” in Proc. Of EMBC'12, San Diego, CA, August 28- September 1, 2012. Published, 08/28/2012.
  • Rahul Kolekar, Daniel Torgerson, John Viner, Bruce Gale and Tim Ameel, “Depth measurement in fully enclosed microchannels using laser interferometry,” Meas. Sci. Technol. Vol. 23, pp. 087004, 2012. Published, 08/2012.
  • Keng-Min Lin, Himanshu J. Sant, Jayant Agarwal and Bruce K. Gale, “New approaches to bridge nerve gaps: Development of a novel drug-delivering nerve conduit,” 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (IEEE EMBS). August, 2012. Paper WeB 15.7. Published, 08/2012.
  • Harikrishnan Jayamohan, Himanshu J. Sant, and Bruce K. Gale, “Applications of Microfluidics for Molecular Diagnostics,” in Microfluidic Diagnostics: Methods and Protocols, Volume 2: Application Protocols and Commercialization, Colin D. Mansfield and Gareth Jenkins, eds., Humana Press: New York, 2012. Published, 06/2012.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Cyclical Magnetic Field Flow Fractionation for the Separation of Magnetic Nanoparticles”, in Proc. of 9th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Minneapolis, MN, May 22-26, 2012. Published, 05/22/2012.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Cyclical Electrical Field Flow Fractionation for the Separation of Magnetic Nanoparticles”, in Proc. of 9th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Minneapolis, MN, May 22-26, 2012. Published, 05/22/2012.
  • Himanshu J. Sant and Bruce K. Gale, “Optimization and Characterization of a Microscale Thermal Field-Flow Fractionation System,” Sensors and Actuators B: Chemical, Vol. 162, No. 1, pp. 223-228, 2012. Published, 05/2012.
  • Himanshu J Sant and Bruce K. Gale, “Characterization Of A Microscale Thermal-Electrical Field-Flow Fractionation System,” Journal of Chromatography A, Vol. 1225, pp. 174-181, 2012. . Published, 04/2012.
  • Srinivas Merugu, Himanshu J. Sant and Bruce K. Gale, “Diffusion Split-Flow Thin Cell (SPLITT) System for protein separations,” Journal of Chromatography B, Vol. 902, pp. 78-83, 2012. Published, 04/2012.
  • T. Onur Tasci, William.P. Johnson, Bruce K. Gale. “Cyclical Magnetic Field Flow Fractionation”. J. Appl. Phys. Vol. 111, pp. 07D128, 2012. Published, 04/2012.
  • Siddharth Chakravarty, Himanshu Sant, Colin Fergusson, and Bruce K. Gale, “Characterization of polymerized liposomes using a combination of normal and cyclical electrical field flow fractionation,” Anal. Chem., Vol. 84, pp. 8323-8329, 2012. Published, 03/2012.
  • Wilaiwan Somchue, Atitaya Siripinyanond and Bruce K. Gale, “Electrical Field-Flow Fractionation for Metal Nanoparticles Characterization,” Anal. Chem, Vol. 84, pp. 4993-4998, 2012. Published, 03/2012.
  • Douglas Anjewierden, Gregory A. Liddiard, and Bruce K. Gale, “An electrostatic microvalve for pneumatic control of microfluidic systems,” J. Micromech. Microeng. Vol. 22, pp. 025019 (9pp), 2012. Published, 02/2012.
  • Srinivas Merugu, Himanshu J. Sant, and Bruce K. Gale, “A novel method for effective field measurements in electrical field-flow fractionation,” Electrophoresis, Vol. 33, pp. 1040–1047, 2012. Published, 02/2012.
  • Jungkyu Kim, Michael A. Johnson, Parker Hill, and Bruce K. Gale, “A microfluidic nucleic acid extraction system with both disposable and reusable components,” J. Micromech. Microeng. Vol. 22, pp. 015007 (9pp), 2012. Published, 01/2012.
  • Himanshu J. Sant, Michael Johnson, and Bruce K. Gale, “Integrated Microfluidics For Serotype Identification Of Foot-And- Mouth-Disease Virus,” in Proc. of MicroTAS 2011, Seattle, WA, USA, October 2-6, 2011, pp. 2007-2009. Published, 10/2011.
  • Rohit Sharma and Bruce K. Gale, “Electrochemical Quantification of DNA Using Aluminum Oxide Membranes,” in Proc. of Eurosensors XXV, September 4-7, 2011, Athens, Greece, pp. 1578-1581. Published, 09/2011.
  • Raheel Samuel, Himanshu J Sant, Fangxiang Jiao, Chris R Johnson and Bruce K Gale, ‘Microfluidic laminate-based phantom for diffusion tensor-magnetic resonance imaging,” J. Micromech. Microeng. Vol. 21, pp. 095027 (11pp), 2011. Published, 08/2011.
  • Julien Gigault , Bruce K. Gale , Isabelle Le Hécho , and Gaëtane Lespes, “Nanoparticle characterization by Cyclical Electrical Field-Flow Fractionation, Anal. Chem. Vol. 83, No. 17, p 6565-6572, 2011. DOI: 10.1021/ac2008948. Published, 08/2011.
  • Balamurali K. Ambati, Gilbert Wong, Griffin J. Jardine, Bruce Gale and John Elsnab, “Endocapsular Carousel Technique Phacoemulsification,” Journal of Cataract & Refractive Surgery, Vol. 37, No. 3, pp. 433-437, 2011. Published, 02/2011.
  • Raheel Samuel, Himanshu Jayant Sant, Fangxiang Jiao, Christopher R. Johnson, and Bruce K. Gale, “Fabrication of a MRI Standardization Device From Stacking Highly Patterned Thin PDMS Layers,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 744a. Published, 11/2010.
  • Keng-Min Lin, Corey J. Bishop, Himanshu J. Sant, Balamurali K. Ambati, and Bruce K. Gale, “Refilling Mechanism to Stabilize a Free-Floating Intraocular Capsule Drug Ring (CDR),” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 568v. Published, 11/2010.
  • Michael A. Johnson, Jungkyu Kim, Angela Williams, and Bruce K. Gale, “A Fully Automated Microfluidic Platform for Nucleic Acid Extraction,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 258b. Published, 11/2010.
  • Daniel Torgerson, Rahul Kolekar, Bruce Gale, and Tim Ameel, “Minor Losses In Rectangular Xurographic Microchannels,” in Proceedings of the ASME International Mechanical Engineering Conference & Exposition (IMECE2010), November 12-18, 2010, Vancouver, British Columbia, Canada, paper 39401 (10 pages). Published, 11/2010.
  • Himanshu Jayant Sant, Scott Sundberg, Erik Liddiard, Michael A. Johnson, and Bruce K. Gale, “Integrated Microfluidics for Serotype Identification of Foot and Mouth Disease Virus,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314f. Published, 11/2010.
  • Venu M. Arremsetty and Bruce K Gale, “Asymmetrical Cross-Flow Based Split Thin Cell Fractionation,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314g. Published, 11/2010.
  • Michael A. Johnson, Jungkyu Kim, Angela Williams, and Bruce K. Gale, “A Programmable Microfluidic System for Selective RNA or DNA Extraction From Various Raw Biological Sample,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314a. Published, 11/2010.
  • Greg A. Liddiard and Bruce K. Gale, “Pneumatically Controlled 32 Channel Scalable Disposable Microfluidic Sample Handling Device with Integrated Metering, Mixing, and Demultiplexing,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 258a. Published, 11/2010.
  • Bruce K. Gale, “Lessons Learned by An Entrepreneurial Minded University Professor On the Creation of New Companies,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 287c. Published, 11/2010.
  • Greg A. Liddiard, Erik Liddiard, and Bruce K. Gale, “Pneumatically Driven 16 Channel Disposable Nucleic Acid Filter Device with Integrated Demultiplexing and Multiplexing,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314d. Published, 11/2010.
  • Michael A. Johnson, Erik Liddiard, and Bruce K. Gale, “A Masked Corona Discharge Method for Selective Bonding in PDMS for Microfluidic Applications,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314i. Published, 11/2010.
  • Erik Liddiard, Himanshu Jayant Sant, Frederic Horndli, and Bruce K. Gale, “Measurement of Muscle Force in C. Elegans Worm Using Microfluidics,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314h. Published, 11/2010.
  • Catherine Maltbie, Ian Papautsky, Suzanne van den Hoogenhof, David Eddington, Bruce Gale, Jin-Woo Choi, Glenn Walker, “Expanding the introduction of microfluidics through a problem-based laboratory course to multiple engineering disciplines at five universities,” IEEE Frontiers in Education Conference (FIE 2010), Washington DC, October 27 - 30, 2010, Paper S2F-6. Published, 10/2010.
  • Raheel Samuel, Himanshu J. Sant, Fangxiang Jiao, Christopher R. Johnson, and Bruce K. Gale, “Fabrication Of A MRI Standardization Device By Stacking Highly Patterned Thin PDMS Layers,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 1901-1903. Published, 10/2010.
  • Himanshu Sant, Scott Sundberg, Adam Miles, Michael Johnson, Erik Liddiard, and Bruce Gale, “Integrated Microfluidics For Serotype Identification Of Foot And Mouth Disease Virus,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 1832-1834. Published, 10/2010.
  • Michael Johnson, Jungkyu Kim, Angela Williams, and Bruce Gale, “A Programmable Microfluidic System For Selective RNA Or DNA Extraction From Various Raw Biological Samples,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 387-389. Published, 10/2010.
  • Catherine Maltbie, Ian Papautsky, Suzanne van den Hoogenhof, David Eddington, Bruce Gale, Jin-Woo Choi, Glenn Walker, “Expanding the introduction of microfluidics through a problem-based laboratory course to multiple engineering disciplines at five universities,” IEEE Frontiers in Education Conference (FIE 2010), Washington DC, October 27 - 30, 2010, Paper S2F-6. Published, 10/2010.
  • Merugu Srinivas, Himanshu Sant, and Bruce K. Gale, “Optimization of Cyclical Electrical Field Flow Fractionation,” Electrophoresis, Vol. 31 (20), pp. 3372-3379, 2010. Published, 08/2010.
  • Himanshu J. Sant, Tammy Ho, and Bruce K. Gale, “An In situ Heater for a Phase-Change-Material-based Actuation System,” JMM. Vol. 20, pp. 085039 (7pp), 2010. Published, 06/2010.
  • T. O. Tasci, A. Arat, E. Atalar, B. Gale, “Utilization of AC and DC Magnetic Fields for Focused Magnetic Fluid Hyperthermia and Magnetic Particle Fractionation,” in Proc. of 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers - Rostock, Germany, May 25-29, 2010, paper 194. Published, 05/2010.
  • Jitae Kim, Michael Mauk, Dafeng Chen, Jungkyu Kim, Bruce Gale, and Haim H. Bau, “A PCR Reactor With an Integrated Alumina Isolation Membrane,” Analyst, Vol. 135, pp. 2408–2414, 2010. Published, 05/2010.
  • Jungkyu Kim, Adam Miles, and Bruce K. Gale, “Improved biomolecule microarrays by printing on nanoporous aluminum oxide using a continuous-flow microspotter,” Small, Vol. 6, No. 13, pp. 1415–1421, 2010. Published, 05/2010.
  • Guang Yan, Kevin S. Warner, Jie Zhang, Sanjay Sharma, and Bruce K. Gale, “Evaluation needle length and density of microneedle arrays in the pretreatment of skin for transdermal drug delivery,” International Journal of Pharmaceutics, Vol. 391, pp. 7-12, 2010. Published, 04/2010.
  • Danny Blanchard, Phil Ligrani, Bruce Gale, “Slip Due to Surface Roughness for a Newtonian Liquid in a Viscous Micro-Scale Disk Pump,” Physics of Fluids, Vol. 22, No. 5, pp. 052002 (15 pgs), 2010. Published, 04/2010.
  • Sarah Molokhia, Himanshu J Sant; Jacquelyn M Simonis; Corey J Bishop; R. Michael Burr; Bruce K Gale; and Balamurali K Ambati, “The Capsule Drug Device: Novel Approach for Drug Delivery to the Eye,” Vision Research, Vol. 50, No. 7, pp. 680-685, 2010. Published, 02/2010.
  • Scott Sundberg, Carl Wittwer, Chao Gao, and Bruce Gale, “Spinning Disc Platform for Microfluidic Digital PCR,” Anal. Chem, Vol. 82, pp. 1546-1550, 2010. Published, 02/2010.
  • Jungkyu Kim, John Elsnab, Michael Johnson, Bruce K. Gale, “Sample to Answer: A Fully Integrated Nucleic Acid Identification System For Bacteria Monitoring,” in Proc. Of SPIE: Microfluidics, BioMEMS, and Medical Microsystems VIII, San Francisco, CA, January 23-28, 2010, Vol. 7593, pp. 75930S, 2010. doi: 10.1117/12.844856. Published, 01/2010.
  • Jianping Liu, Mark A. Eddings, Rostislav Bukasov, Bruce K. Gale, Jennifer S. Shumaker-Parry, “In Situ Microarray Fabrication and Analysis Using a Microfluidic Flow Cell Array Integrated with Surface Plasmon Resonance Microscopy,” Anal. Chem., Vol. 81, No. 11, pp 4296–4301, 2009. Published, 2009.
  • Daniel A. Bartholomeusz, Ronald W. Boutté and Bruce K. Gale. “Xurography: Microfluidic Prototyping with a Cutting Plotter,” in Lab-on-a-Chip Technology: Fabrication and Microfluidics., Keith E. Herold and Avraham Rasooly, eds. Caister Academic Press: Norwich, UK, 2009. Published, 2009.
  • Jungkyu Kim and Bruce K. Gale, “Rapid prototyping of microfluidic systems using a PDMS/polymer tape composite,” Lab. Chip, Vol. 9, pp. 1290-1293, 2009. Published, 2009.
  • Niel Crews, Carl Wittwer, Jesse Montgomery, Robert Pryor, Bruce K. Gale, “DNA Melting Analysis for Genotyping and Variant Scanning,” Anal. Chem. Vol. 81, No. 6, pp. 2053-2058, 2009. Published, 2009.
  • Jungkyu Kim, Michael Junkin, Deok-Ho Kim, Seunglee Kwon, Young Shik Shin, Pak Kin Wong, and Bruce K. Gale, “Applications, Techniques, and Microfluidic Interfacing for Nanoscale Biosensing,” Microfluidics and Nanofluidics, Vol. 7, No. 2, pp. 149-167, 2009. Published, 2009.
  • Danny Blanchard, Phil Ligrani, Bruce Gale, “Slip Due to Surface Roughness for a Newtonian Liquid in a Viscous Micro-Scale Disk Pump,” Physics of Fluids, submitted. Accepted, 2009.
  • Ryan Sincic, David A. Chang-yen, Louis Barrows, Bruce K. Gale, “Parallel Determination of Phenotypic Cytotoxicity with a Micropattern of Mutant Cell Lines,” Biomed. Microdev., Vol. 11, No. 2, pp. 443-452, 2009. Published, 2009.
  • Mark A. Eddings, Josh W. Eckman, Carlos A. Arana, John E. Connolly, Bruce K. Gale, and David G. Myszka, “Spot-and-Hop Interspot Referencing for Surface Plasmon Resonance Imaging Using a Three-Dimensional Microfluidic Flow Cell Array,” Anal. Biochem., Vol. 385, No. 2, pp. 309-313, 2009. Published, 2009.
  • Rebecca L. Rich, Adam R. Miles, Bruce K. Gale, and David G. Myszka, “Detergent screening of a GPCR using serial and array biosensor technologies,” Anal. Biochem. Vol. 386, No. 1, pp. 98-104, 2009. Published, 2009.
  • Jungkyu Kim, Michael A. Johnson, Parker Hill, and Bruce K. Gale, “A microfluidic nucleic acid extraction system with both disposable and reusable components,” Biomed. Microdev. submitted. Submitted, 2009.
  • Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale, “Microfluidic sample preparation: cell lysis and nucleic acid purification,” Integr. Biol., Vol. 1, No. 10, pp. 574 – 586, 2009. Published, 2009.
  • James R. Joubert, Kathryn A. Smith, Erin Johnson, John P. Keogh, Vicki H. Wysocki, Bruce K. Gale, John C. Conboy, and S. Scott Saavedra, “Stable, ligand-doped, poly(bis-SorbPC) lipid bilayer arrays for protein binding and detection,” ACS Applied Materials and Interfaces, Vol. 1, No. 6, pp. 1310-1315, 2009. Published, 2009.
  • Michael Johnson, Greg Liddiard, Mark Eddings, and Bruce Gale, “Bubble inclusion and removal using PDMS membrane-based gas permeation for applications in pumping, valving, and mixing in microfluidic devices,” J. Micromech. Microeng., Vol. 9, pp. 095011 (9 pp), 2009. Published, 2009.
  • Himanshu J. Sant and Bruce K. Gale, “Flexible fabrication, packaging, and detection approach for microscale chromatography systems,” Sens. Act. B, Vol. 141, No. 1, pp. 316-321, 2009. Published, 2009.
  • Sriram Natarajan, Phini S. Katsamba, Adam Miles, Josh Eckman, Giuseppe A. Papalia, Rebecca L. Rich, Bruce Gale, David G. Myszka, “Continuous-flow microfluidic printing of proteins for array-based applications including surface plasmon resonance imaging,” Anal. Biochem. Vol. 373, pp. 141-146, 2008. Published, 2008.
  • Sriram Natarajan, Andrew Hatch, David Myszka, and Bruce Gale, “Optimal Conditions for Protein Array Deposition using a Continuous Flow Microspotter,” Anal. Chem., Vol. 80, No. 22, pp. 8561-8567, 2008. Published, 2008.
  • Mark A. Eddings, Michael A. Johnson, and Bruce K. Gale, “Determining the optimal PDMS-PDMS bonding technique for microfluidic devices, J. Micromech. Microeng. Vol. 18, pp. 067001 (1-4), 2008. Published, 2008.
  • Niel Crews, Carl Wittwer, Robert Palais, and Bruce Gale, “Product Differentiation during Continuous-Flow Thermal Gradient PCR,” Lab. Chip, Vol. 8, pp. 919 - 924, 2008. Published, 2008.
  • Sriram Natarajan, David Chang-Yen, and Bruce Gale, “Large-area, high-aspect-ratio SU-8 molds for fabrication of PDMS microfluidic devices,” J. Micromech. Microeng. Vol. 18, 045021, 2008. Published, 2008.
  • Niel Crews, Carl Wittwer, and Bruce Gale, “Thermal Gradient PCR in a Continuous-Flow Microchip,” Biomed. Microdevices, Vol. 10, No. 2, 2008. Published, 2008.
  • Niel Crews, Timothy A. Ameel, Carl Wittwer, and Bruce Gale, “Flow-Induced Thermal Effects on Spatial DNA Melting,” Lab. Chip, Vol. 8, pp. 1922-1929, 2008. Published, 2008.
  • Mark A. Eddings, Adam Miles, Josh Eckman, Jungkyu Kim, Rebecca L. Rich, Bruce K. Gale, and David Myszka, “Improved continuous-flow print head for micro-array deposition,” Anal. Biochem,. Vol. 382, No. 1, pp. 55-59, 2008. Published, 2008.
  • Jungkyu Kim and Bruce K. Gale, “Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlOx membrane,” Lab. Chip, Vol. 8, pp. 1516 - 1523, 2008. Published, 2008.
  • Kathryn A. Smith, Bruce K. Gale, John C. Conboy, “Micropatterned fluid lipid bilayer array,” Anal. Chem. Vol. 80, No. 21, pp. 7980-7987, 2008. Published, 2008.
  • Bruce K. Gale, Mark A. Eddings, Scott O. Sundberg, Andrew Hatch, JungKyu Kim, and Tammy Ho. “ Fabrication and packaging: Low-cost MEMS technologies,” in Comprehensive Microsystems, 1st Ed. Yogesh B. Gianchandani, Osamu Tabata, Hans Zappe, eds. Elsevier Amsterdam, 2008. Published, 2008.