Bruce Gale
  • Chair, Mechanical Engineering
  • Adjunct Professor, Materials Science and Engineering
  • Adjunct Professor, Elect & Computer Engineering
  • Adjunct Professor, Biomedical Engineering
  • Professor, Mechanical Engineering

Publications

  • Azapagic A, Agarwal J & Gale B (2024). A Novel Vascular Anastomotic Coupling Device for End-to-End Anastomosis of Arteries and Veins. IEEE transactions on bio-medical engineering. Vol. 71, 542552542-552. Published, 01/01/2024.
  • Greg Liddiard, Bahar Kazemi, Munawar Jawad, Chris Lambert, Sabin Nepal & Bruce Gale (2023). AN INTEGRATED, AUTOMATED MICROFLUIDIC INSTRUMENT FOR COMPLEX BIOLOGICAL MICROREACTIONS. Proc. Of MicroTAS 2023, Kaowice, Poland. Published, 10/15/2023.
  • Christopher J Lambert, Harikrishnan Jayamohan, Bruce K Gale, Lars B Laurentius, Dhruv Patel, Madison Hansen, Tawsif Mahmood & Himanshu Sant (2023). Electrochemical Detection of SARS-CoV-2 Using Immunomagnetic Separation and Gold Nanoparticles on Unmodified Screen-Printed Carbon Electrodes. Applied Sciences. Vol. 13, 10007. Published, 09/05/2023.
    https://www.mdpi.com/2076-3417/13/18/10007
  • Tan Z, Zhao W, Yin Y, Xu M & Pan W (2022). Insight into the formation and biological effects of natural organic matter corona on silver nanoparticles in water environment using biased cyclical electrical field-flow fractionation. Water research. Vol. 228, 119355119355. Published, 12/01/2022.
  • Dhruv Patel, Ugo Nze, Chris Lambert, Hari Jayamohan, Haidong Feng, Bruce Gale & Himanshu Sant (2022). Design of a hydrodynamic cavitation system for the extraction and detection of Escherichia coli (O157:H7) from ground beef. Sensors and Actuators B Chemical. Vol. 369, 132370. Published, 10/15/2022.
    https://doi.org/10.1016/j.snb.2022.132370
  • Wojtalewicz S, Vizmeg J, Erickson S, Lade C & Shea J (2022). Evaluating the influence of particle morphology and density on the viscosity and injectability of a novel long-acting local anesthetic suspension. Journal of biomaterials applications. Vol. 37, 724736724-736. Published, 10/01/2022.
  • Farhad Shiri, Haidong Feng, and Bruce K. Gale, “Passive and Active Microfluidic Separation Methods,”in Particle Separation Techniques, Catia Cantado, ed, Elsevier: Amsterdam, pp. 450-484, 2022. Published, 08/2022.
  • Nusrat Tazin, Dhruv Patel, Chris Lambert, Mohi Shad, Jeff Campbell & Bruce Gale (2022). Automated passive serial dilution microfluidic chip for calcium quantification based on the Arsenazo III method. Sensors and Diagnostics. Vol. 1, 810-820. Published, 06/13/2022.
    https://doi.org/10.1039/D2SD00022A
  • Petersen K, Shiri F & Tasci TO (2021). Experiment, theory, and simulation of a flow-electrical-split flow thin particle separation device. Journal of chromatography. A. Vol. 1659, 462634462634. Published, 11/01/2021.
  • Brady Goenner & Bruce Gale (2021). High-Strength Adhesive Bonding Of 3D Printed Microfluidic Devices To PDMS. Proc. Of MicroTAS 2021, Palm Springs, CA. T2C-311. Published, 10/11/2021.
  • Utpal Saha, Bruce Gale & Raheel Samuel (2021). Eliminating Reinjection- Droplet Generation and Sorting In The Same Chip. Proc. Of MicroTAS 2021, Palm Springs, CA. M1A-200C. Published, 10/07/2021.
  • Nelson J, Patel D & Sant HJ (2021). Compression of the vascular wall to create a friction fit in a vascular anastomotic coupler. Journal of the mechanical behavior of biomedical materials. Vol. 123, 104681. Published, 09/01/2021.
  • Feng H, Jafek A & Samuel R (2021). High efficiency rare sperm separation from biopsy samples in an inertial focusing device. The Analyst. Vol. 146, 3368-3377. Published, 05/01/2021.
  • Davis B, Erickson S, Wojtalewicz S, Simpson A, Metcalf C, Sant H, Shea J, Gale B & Agarwal J (2021). Entrapping bupivacaine-loaded emulsions in a crosslinked-hydrogel increases anesthetic effect and duration in a rat sciatic nerve block model. International journal of pharmaceutics. Vol. 588, 119703. Published, 02/01/2021.
  • Shiri F, Gale BK, Sant H, King B, Bardi GT, Hood JL & Petersen KE (2021). Development and Testing of a Continuous Flow-Electrical-Split-Flow Lateral Transport Thin Separation System (Fl-El-SPLITT). Analytical chemistry. Vol. 93, 2888-2897. Published, 02/01/2021.
  • Shiri F, Gale BK, Sant H, Bardi GT, Hood JL & Petersen KE (2021). Characterization of Human Glioblastoma versus Normal Plasma-Derived Extracellular Vesicles Preisolated by Differential Centrifugation Using Cyclical Electrical Field-Flow Fractionation. Analytical chemistry. Vol. 92, 9866-9876. Published, 02/01/2021.
  • Labroo P, Ho S, Sant H, Shea JE, Agarwal J & Gale B (2021). Modeling diffusion-based drug release inside a nerve conduit in vitro and in vivo validation study. Drug delivery and translational research. Vol. 11, 154-168. Published, 01/01/2021.
  • Jayamohan H, Lambert CJ, Sant HJ, Jafek A, Patel D, Feng H, Beeman M, Mahmood T, Nze U & Gale BK (2021). SARS-CoV-2 pandemic: a review of molecular diagnostic tools including sample collection and commercial response with associated advantages and limitations. Analytical and bioanalytical chemistry. Vol. 413, 49-71. Published, 01/01/2021.
  • Mangum CL, Patel DP, Jafek AR, Samuel R, Jenkins TG, Aston KI, Gale BK & Hotaling JM (2020). Towards a better testicular sperm extraction: novel sperm sorting technologies for non-motile sperm extracted by microdissection TESE. Translational andrology and urology. Vol. 9, S206-S214. Published, 09/01/2020.
  • Alex Jafek, Haidong Feng, Dallin Broberg, Bruce Gale, Timothy Jenkins, Kenneth Aston & Raheel Samuel (2020). Optimization of Dean-flow microfluidic chip for sperm preparation for intrauterine insemination. Microfluidics and Nanofluidics. Vol. 24. Published, 07/13/2020.
    https://link.springer.com/article/10.1007/s10404-0...
  • Samuel R, Son J, Jenkins TG, Jafek A, Feng H, Gale BK, Carrell DT & Hotaling JM (2020). AUTHOR REPLY. Urology. Vol. 140, 75-76. Published, 05/01/2020.
  • Samuel R, Son J, Jenkins TG, Jafek A, Feng H, Gale BK, Carrell DT & Hotaling JM (2020). Microfluidic System for Rapid Isolation of Sperm From Microdissection TESE Specimens. Urology. Vol. 140, 70-76. Published, 05/01/2020.
  • Shiri F, Petersen KE, Romanov V, Zou Q & Gale BK (2020). Characterization and differential retention of Q beta bacteriophage virus-like particles using cyclical electrical field-flow fractionation and asymmetrical flow field-flow fractionation. Analytical and bioanalytical chemistry. Vol. 412, 1563-1572. Published, 04/01/2020.
  • Shao L, Petersen K, Shiri F, Feng H & Gale B (2020). Characteristics of electrical field flow fractionation with chronoamperometry and electrochemical impedance. Micro And Nano Letters. Vol. 15, 13-17. Published, 01/15/2020.
    https://digital-library.theiet.org/content/journal...
  • Davis B, Hilgart D, Erickson S, Labroo P, Burton J, Sant H, Shea J, Gale B & Agarwal J (2020). Local FK506 delivery at the direct nerve repair site improves nerve regeneration. Muscle & nerve. Vol. 60, 613-620. Published, 01/01/2020.
  • Feng H, Magda JJ & Gale BK (2019). Viscoelastic second normal stress difference dominated multiple-stream particle focusing in microfluidic channels. Applied physics letters. Vol. 115, 263702. Published, 12/23/2019.
  • Chaharlang M, Cernucan K & Gale B (2019). Focusing Mechanism of Non-Spherical Particles in Microchannels. (pp. 13851). Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah, USA. Published, 11/10/2019.
  • Jafek A, Feng H, Brady H, Chaharlang M, Petersen K, Broberg D, Hotaling J, Carrell D, Samuel R, Aston K, Jenkins T & Gale B (2019). Microfluidic Sperm Preparation for Intrauterine Insemination. (pp. 13401). Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah, USA. Published, 11/10/2019.
  • Feng H, Jafek A, Jenkins T, Aston K & Gale B (2019). Self-Alignment Induced Sperm Separation in Inertial Focusing Device. (pp. 13884). in Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah. Published, 11/10/2019.
  • Saha U, Shin D, Sant H, Chang J & Gale B (2019). Rapid Prototyping of Microfluidic Channels Using Electro-Spun Nano-Fiber Mold. (pp. 12874). Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah, USA. Published, 11/10/2019.
  • Feng H, Ervin E, German S, Wisniewski J, Krupta M & Gale B (2019). An Integrated Nanofluidic System for Blood Sample Ion Current Rectification (ICR) Biosensing. (pp. 13047). Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah, USA. Published, 11/10/2019.
  • Nze UC, Beeman MG, Lambert CJ, Salih G, Gale BK & Sant HJ (2019). Hydrodynamic cavitation for the rapid separation and electrochemical detection of Cryptosporidium parvum and Escherichia coli O157:H7 in ground beef. Biosensors & bioelectronics. Vol. 135, 137-144. Published, 11/01/2019.
  • A Jafek, Feng H, Brady H, Samuel R & Gale B (2019). PEO Can Improve The Resolution Of Size-Based Separations In Spiral Channels. Proc. Of MicroTAS 2019. W220h. Published, 10/31/2019.
  • Charharlang M, Goenner B & Gale B (2019). Unravel The Physics Of Particle Focusing Mechanisms In Microchannels. Proc. Of MicroTAS 2019. T131d. Published, 10/31/2019.
  • Nelson M, Ramkumar N & Gale B (2019). Flexible, Transparent, Sub-100 µm Microfluidic Channels With FDM 3D-Printed Thermoplastic Polyurethane. Proc. Of MicroTAS 2019. M149e. Published, 10/31/2019.
  • Bruce K Gale & 5. Alexander R. Jafek, Chris Lambert, Brady Goenner, Hossein Moghimifam, Ugochukwu Nze, Suraj Kumar, (2018). A Review of Current Methods in Microfluidic Device Fabrication and Future Commercialization Prospects. Inventions. Vol. 3, 25. Published, 08/20/2018.
    https://doi.org/10.3390/inventions3030060
  • Nze U, Lambert C, Gale B & Sant H (2018). A Rapid Cryptosporidium Biosensor based on the Electrochemical Detection of Polyguanine. Proc. Of EMBC 2018. Published, 07/18/2018.
  • Bruce K Gale (2018). The History and Applications of Electrical Field Flow Fractionation. Proc. Of 18th International Symposium on Field-and Flow-based Separations. Published, 05/14/2018.
  • Scott Ho & Pratima Labroo, Keng-min Lin, Himanshu Sant, Jill Shea, Bruce K. Gale, Jay Agarwal (2018). Designing a bioresorbable drug delivery conduit to promote nerve regeneration-a preliminary study. Journal of Medical and Biological Engineering. Published, 03/09/2018.
    https://doi.org/10.1007/s40846-018-0393-y
  • Ching-Wen Li, Jill Shea, Himanshu Sant, Jay Agarwal & Bruce K. Gale (2018). Optimization of Micropatterned PLGA Films for Enhancing Dorsal Root Ganglion Cell Orientation and Extension. Neural Regeneration Research. Vol. 13, 105-111. Published, 01/15/2018.
    http://www.nrronline.org/article.asp?issn=1673-537...
  • Ryan Brewster, Jay Agarwal,, Bruce K. Gale, Himanshu J. Sant, Ken Monson & Jill Shea (2017). A Biodegradable Vascular Coupling Device for End-to-End Anastomosis. Journal of Medical and Biological Engineering. Published, 12/07/2017.
    https://link.springer.com/article/10.1007%2Fs40846...
  • Pratima Labroo, Jill Shea, Kyle Edwards,, Scott Ho,, Brett Davis,, Himanshu Sant, Isak Goodwin, Bruce K. Gale & Jay Agarwal, (2017). Novel drug delivering conduit for peripheral nerve regeneration. Journal of Neural Engineering,. Vol. 14, 066011. Published, 11/13/2017.
    http://iopscience.iop.org/article/10.1088/1741-255...
  • T. Jenkins, R. Samuel, A. Jafek, H. Feng, B. Gale,, D. T. Carrell & J. M. Hotaling, (2017). Rapid Microfluidic Sperm Isolation From Microtese Samples In Men With Nonobstructive Azoospermia. Proc. Of ASRM 2017 Scientific Congress & Expo. P360. Published, 10/28/2017.
  • A.R. Jafek, H. Brady, S. Harbertson, A. Millington, R. Samuel & B. Gale (2017). Quantifying Microfluidic PCR At Extreme Speeds. Proc. Of MicroTAS 2017. 1229-1230. Published, 10/22/2017.
  • H. Feng, T. Jenkins, A. Jafek, R. Samuel & B.K. Gale (2017). Enhanced Focusing And Separation Of Sperm Cell In Microfluidic Inertial Separation Device With Viscoelastic Liquid,. Proc. Of MicroTAS 2017. 1367-1368. Published, 10/22/2017.
  • Joshua L. Hood, Gina T. Bardi , Kevin E. Petersen , Himanshu Sant & Bruce K. Gale (2017). Cyclical Electrical Field-Flow Fractionation of Melanoma Exosomes. Proc. Of ASEMV 2017. Published, 10/08/2017.
  • Joshua L. Hood, Gina T. Bardi, Kevin E. Petersen, Himanshu Sant & Bruce K. Gale, (2017). Cyclical Electrical Field-Flow Fractionation of Melanoma Exosomes: Enabling Unprecedented "Label-Free" Isolation of Exosome Subpopulations based on Biophysical Properties. Proc. Of Research!Louisville 2017. Published, 09/14/2017.
  • Jiyoung Son, Raheel Samuel,, Bruce K. Gale, Douglas T. Carrell & James M. Hotaling (2017). Separation Of Sperm Cells From Samples Containing High Concentrations Of White Blood Cells Using A Spiral Channel. Biomicrofluidics. Vol. 11, 054106. Published, 09/01/2017.
    https://aip.scitation.org/doi/abs/10.1063/1.499454...
  • Yuguang Liu, Patricio Jeraldo, Samantha McDonough, Jin Jen,, Robin Patel,, Marina Walther-Antonio, Christopher Lambert & Bruce Gale (2017). Experimental validation of an optofluidic platform for microbial single cell isolation and whole genome amplification for human microbiome applications. 2017 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2017 - Proceedings , Institute of Electrical and Electronics Engineers Inc. 62-66. Published, 05/09/2017.
    http://ieeexplore.ieee.org/document/7985850/
  • Pratima Labroo, Jill E Shea, Himanshu Sant, Bruce K Gale & Jayant Agarwal (2017). Effect of combining FK506 and neurotrophins on axonal branching and elongation. Muscle & Nerve. Vol. 55, 570–581. Published, 03/01/2017.
    http://onlinelibrary.wiley.com/doi/10.1002/mus.253...
  • Jesus Muguruza, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury & Bruce K Gale (2017). Use of a highly parallel Microfluidic Flow Cell Array to determine therapeutic drug dose response curves. Biomedical Microdevices. Vol. 25. Published, 03/2017.
    https://link.springer.com/article/10.1007/s10544-0...
  • Li H, Gale B, Shea J, Sant H, Terry CM & Agarwal J (2017). Vascular Coupling System for End-to-End Anastomosis: An In Vivo Pilot Case Report. Cardiovascular engineering and technology. Vol. 8, 91-95. Published, 02/01/2017.
  • Harikrishnan Jayamohan, Valentin Romanov, Huizhong Li, Jiyoung Son, Raheel Samuel, John Nelson, and Bruce K. Gale, "Advances in Microfluidics and Lab-on-a-Chip Technologies" in Molecular Diagnostics, 3rd Edition.George P. Patrinos, Philip B. Danielson and Wilhelm J. Ansorge, Eds. Academic Press: New York, 2016. Published, 10/2016.
  • Labroo P, Ho S, Sant H, Shea J, Gale BK & Agarwal J (2016). Controlled Delivery of FK506 to Improve Nerve Regeneration. Shock (Augusta, Ga.). Vol. 46, 154-9. Published, 08/01/2016.
  • Labroo P, Shea J, Sant H, Gale B & Agarwal J (2016). Effect Of combining FK506 and neurotrophins on neurite branching and elongation. Muscle & nerve. Published, 08/01/2016.
  • Ragsdale V, Li H, Sant H, Ameel T & Gale BK (2016). A disposable, continuous-flow polymerase chain reaction device: design, fabrication and evaluation. Biomedical microdevices. Vol. 18, 62. Published, 07/01/2016.
  • Samuel R, Badamjav O, Murphy KE, Patel DP, Son J, Gale BK, Carrell DT & Hotaling JM (2016). Microfluidics: The future of microdissection TESE?. Systems biology in reproductive medicine. Vol. 62, 161-70. Published, 05/01/2016.
  • Harikrishnan Jayamohan, York Smith, Bruce K Gale, Swomitra K Mohanty, Manoranjan Misra, “Photocatalytic Microfluidic Reactors Utilizing Titania Nanotubes on Titanium Mesh for Degradation of Organic and Biological Contaminants,” Journal of Environmental Chemical Engineering, Vol. 4(1), 657-663.. Published, 04/30/2016.
  • Reid, Russell C., Jones, Sean R., Hickey, David P., Minteer, Shelley D., & Gale, Bruce K. (2016). Modeling Carbon Nanotube Connectivity and Surface Activity in a Contact Lens Biofuel Cell. Elsevier BV. Vol. 203, 30-40. Published, 04/2016.
  • Lin, Keng-Min, Shea, Jill, Gale, Bruce K, Sant, Himanshu, Larrabee, Patti, Agarwal, Jay (2016). Nerve growth factor released from a novel PLGA nerve conduit can improve axon growth. IOP Publishing. Vol. 26(4), 045016. Published, 04/2016.
  • Chen, Jiao, Zhao, Yi, Yan, Xiaohui, Zhang, Li, Choy, Kwongwai, Hu, Jun, Sant, Himanshu J., Gale, Bruce K., Tang, Tao & Deng, Yan (2016). Transdermal Delivery of siRNA through Microneedle Array. Nature Publishing Group. Vol. 6, 21422. Published, 02/2016.
  • Ornthai M, Siripinyanond A & Gale BK (2016). Effect of Ionic and Nonionic Carriers in Electrical Field-Flow Fractionation. Analytical chemistry. Vol. 88, 1794-803. Published, 02/01/2016.
  • Huizhong Li, Jay Agarwal, Brittany Coats, and Bruce K. Gale,Optimization and Evaluation of a Vascular Coupling Device for End-to-End Anastomosis: A Finite Element Analysis,” Journal of Medical Devices, Vol. 10, No. 3, pp. 011003(1-7), 2016. DOI: 10.1115/1.4031810. Published, 01/01/2016.
  • Ornthai M, Siripinyanond A & Gale BK (2016). Biased cyclical electrical field-flow fractionation for separation of submicron particles. Analytical and bioanalytical chemistry. Vol. 408, 855-63. Published, 01/01/2016.
  • Victoria Ragsdale, Huizhong Li, Tim Ameel, and Bruce Kent Gale, “Three-Dimensional Heat Transfer Analysis Of A Disposable, Continuous-Flow Polymerase Chain Reaction Device,” in Proc. Of MicroTAS 2015, October 25-29, 2015, Gyeongju, Korea, pp. 2038-2040, 2015. Published, 10/29/2015.
  • Jiyoung Son, Odgerel Badamjav, Timothy Gerald Jenkins, Bruce Kent Gale, James M Hotaling, and Douglas T Carrell “Active Higher Quality Sperm Separation Using A Spiral Channel,” in Proc. Of MicroTAS 2015, October 25-29, 2015, Gyeongju, Korea, pp. 367-369, 2015. Published, 10/29/2015.
  • Jesús Arellano, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury, and Bruce K. Gale, “Utilization of a Microfluidic Flow Cell Array in the Implementation of a High-Throughput Drug Screening and Cytotoxicity Evaluation System,” in Proc. of BMES 2015, Tampa, FL, October 7-10, 2015. Published, 10/07/2015.
  • T. Onur Tasci, William P. Johnson, Diego P Fernandez, Eliana Manangon , Bruce K. Gale, “Particle Based Modeling Of Electrical Field Flow Fractionation Systems,” Chromatography, Vol. 2, pp. 594-610, 2015, doi:10.3390/chromatography2040594. Published, 09/01/2015.
  • Jiyoung Son, Kristin Murphy, Raheel Samuel, Bruce K Gale, Douglas Carrell, Jim Hotaling, “Non-Motile Sperm Cell Separation Using A Spiral Channel, Anal. Meth., Vol. 7, pp. 8041 - 8047, 2015. DOI: 10.1039/C5AY02205C. Published, 08/02/2015.
  • Huizhong Li, Cody Gehrke, Bruce K. Gale, Himanshu Sant, Brittany Coats and Jay Agarwal, “A New Vascular Coupler Design for End-to-End Anastomosis: Fabrication and Proof-of-Concept Evaluation,” J. Med. Devices, Vol. 9, No. 3, pp. [031002], 2015. DOI: 10.1115/1.4029924. Published, 07/01/2015.
  • Lespes G, Contado C & Gale BK (2015). Field and flow-based separations. Analytical and bioanalytical chemistry. Vol. 407, 4299-300. Published, 05/01/2015.
  • Davidoff SN, Stallings KL, Brooks AE, Gale BK & Brooks BD (2015). Optimal tube length for the submerged printing of ovarian cancer cells. Biomedical sciences instrumentation. Vol. 51, 17-23. Published, 05/01/2015.
  • Jayamohan H, Gale BK, Minson B, Lambert CJ, Gordon N & Sant HJ (2015). Highly sensitive bacteria quantification using immunomagnetic separation and electrochemical detection of guanine-labeled secondary beads. Sensors (Basel, Switzerland). Vol. 15, 12034-52. Published, 05/01/2015.
  • Reid RC, Minteer SD & Gale BK (2015). Contact lens biofuel cell tested in a synthetic tear solution. Biosensors & bioelectronics. Vol. 68, 142-8. Published, 03/01/2015.
  • Samuel R, Stephenson R, Roy P, Pryor R, Zhou L, Bonkowsky JL & Gale BK (2015). Microfluidic-aided genotyping of zebrafish in the first 48 h with 100% viability. Biomedical microdevices. Vol. 17, 43. Published, 03/01/2015.
  • Huizhong Li, Bruce K. Gale, Himanshu Sant, Jill Shea, E. David Bell and Jay Agarwal, “A Novel Vascular Coupling System for End-to-End Anastomosis,” Cardiovascular Engineering and Technology, Vol. 6 (3), pp. 294-302, 2015. Published, 02/01/2015.
  • Russell Reid, Shelley D Minteer, Bruce K Gale, “Contact Lens Biofuel Cell Tested in a Synthetic Tear Solution,” Biosensors and Bioelectronics, Vol. 68, pp. 142-148, 2015. DOI: 10.1016/j.bios.2014.12.034. Published, 01/2015.
  • Kevin Petersen, Lucia Manangon, Joshua Hood, Samuel Wickline, Diego Fernandez, William Johnson, Bruce K. Gale, “A Review of Exosome Separation Techniques and Characterization of B16-F10 Mouse Melanoma Exosomes with AF4-UV-MALS-QELS-DLS-TEM,” Anal. Bioanal. Chem., Vol. 406 (30), pp. 7855-66, 2014. Published, 12/01/2014.
  • Jiyoung Son, Raheel Samuel, Kristin Murphy, Himanshu Sant, Matthew Hockin, Bruce K. Gale, James M. Hotaling, and Douglas T. Carrell, “Sperm Cell Separation Using A Spiral Channel,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2570-2571. Published, 10/28/2014.
  • T. Onur Tasci, Chris J. Lambert, Himanshu J. Sant, Eliana Manangon, Diego P. Fernandez, William P. Johnson, and Bruce K. Gale, “A Microfluidic System For High Throughput Continuous Separation Of Nanoparticles,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2444-2446. Published, 10/28/2014.
  • Matthew F. Hockin, Himanshu J. Sant, Mario R. Capecchi and Bruce K. Gale, “An inertial microfluidic device for rapid purification of native chromosomes,” in Proc. of MicroTAS 2014, San Antonio, TX, October 26-30, 2014, pp. 2510-2511. Published, 10/21/2014.
  • Mathuros Ornthai, Bruce K. Gale, Juwadee Shiowatan and Atitaya Siripinyanond, “Biased Cyclical Electrical Field-Flow Fractionation for Separation of Submicron Particles,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. P8, 2014. Published, 10/14/2014.
  • Mathuros Ornthai, Kevin E. Petersen, Bruce K. Gale, Jiyoung Son, and Atitaya Siripinyanond, “Separation of Biological Particles: El-FFF and Spiral Channels,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. O33, 2014. Published, 10/14/2014.
  • Ian R. Harvey, Bruce Gale, Tom Parks, Richard Brown, Florian Solzbacher, “USTAR / U of U / COE Partnerships to Spur R&D in micro/nano Materials & Systems, in Proc. Of COMS 2014, Salt Lake City, UT, October 12-16, 2014. Published, 10/14/2014.
  • Matthew Hockin, Himanshu Sant, Kevin Petersen, Bruce Gale, “Separation of Chromosomes Using FFF and Inertial Microfluidics,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. O18, 2014. Published, 10/14/2014.
  • Kevin E. Petersen, Mathuros Ornthai, Joshua Hood, Sam Wickline, and Bruce K. Gale, “Electrical Field Flow Fractionation of Exosomes,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Salt Lake City, UT, October 14-18, 2014, pp. P22, 2014. Published, 10/14/2014.
  • Jesús Arellano, James Gammon, Chieh-Hsiang Yang, Margit Janat-Amsbury, and Bruce K. Gale, “Development of Continuous Flow Microspotter (CFM) for High-Throughput Drug Screening and Cytotoxicity Evaluation,” in Proc. of BMES 2014, San Antonio, TX, October 22-25, 2014. Published, 10/01/2014.
  • Scott Ho, Pratima Labroo, Keng-Min Lin, Himanshu Sant, Jill Shea, Jay Agarwal, Bruce Gale, “Bioresorbable Multi-Drug Delivery Conduit to Promote Peripheral Nerve Regeneration,” in Proc. of BMES 2014, San Antonio, TX, October 22-25, 2014. Published, 10/01/2014.
  • Raheel Samuel, Colin M Thacker, A. Villu Maricq and Bruce K. Gale, “Simple and cost-effective fabrication of microvalve arrays in PDMS using laser cut molds with application to C. elegans manipulation in microfluidics,” Journal of Micromechanics and Microengineering, Vol. 24(10), pp. 105007 (8 pages), 2014. DOI: 10.1088/0960-1317/24/10/105007. Published, 10/01/2014.
  • Tonguc O. Tasci, William. P. Johnson, Diego. P. Fernandez, Eliana. Manangon, Bruce. K. Gale, “Circuit modification in electrical field flow fractionation systems generating higher resolution separation of nanoparticles,” J. Chromatography A, Vol. 1365, pp. 164–172, 2014. DOI: 10.1016/j.chroma.2014.08.097. Published, 09/01/2014.
  • Huizhong Li, Bruce Gale, Himanshu Sant, Jill Shea, and Jay Agarwal, “Design, Fabrication and Testing of A Novel End-to-End Vascular Coupling System,” in Proc. EMBC 2014, Chicago, IL, August 26-30, 2014. Published, 08/26/2014.
  • Bruce K. Gale, Raheel Samuel, Harikrishnan Jayamohan, and Himanshu Sant, “Microfluidic Devices for Rapid and Sensitive Identification of Organisms,” in Proc. EMBS 2014, Chicago, IL, August 28-31, 2014. Published, 08/01/2014.
  • Scott O. Sundberg, Carl T. Wittwer, Luming Zhou, Robert Palais, Zachary Dwight, and Bruce K. Gale, “Quasi-Digital PCR: Enrichment and Quantification of Rare DNA Variants,” Biomedical Microdevices, Vol. 16(4), pp. 639-644, August 2014. doi: 10.1007/s10544-014-9866-0. Published, 08/01/2014.
  • Valentin Romanov, S. Nikki Davidoff, Adam R. Miles, David W. Grainger, Bruce K. Gale, and Benjamin D. Brooks, “A Critical Comparison of Protein Microarray Fabrication Technologies,” Analyst, Vol. 139 (6), pp. 1303-1326, 2014. doi: 10.1039/c3an01577g. Published, 06/01/2014.
  • S. Nikki Davidoff, Adam R. Miles, Bruce K. Gale, Josh W. Eckman, and Benjamin D. Brooks, “The Submerged Printing of Cells onto a Modified Surface Using a Continuous Flow Microspotter,” J. Vis. Exp. (86), e51273, 2014. doi:10.3791/51273. Published, 06/01/2014.
  • R Samuel, R Stephenson, P Roy, R Pryor, L Zhou, J L Bonkowsky, B K Gale “Microfluidic methods for early-stage zebrafish embryo genotyping while maintaining embryo viability” 2014 International Conference on Zebrafish Development and Genetics, Madison, USA. Published, 05/01/2014.
  • Davidoff SN, Miles AR, Romanov V, Gale BK, Eckman JW & Brooks BD (2014). The submerged printing of cells onto a modified surface using a continuous flow microspotter. Journal of visualized experiments : JoVE. Published, 05/01/2014.
  • Wei Chen, Chong Wang, Li Yan, Longbiao Huang, Xiaoyue Zhu, Bing Chen, Himanshu J Sant, Xinrui Niu, Val Roy, Bruce K Gale, Xianfeng Chen, “Improved polyvinylpyrrolidone microneedle arrays with non-stoichimetric cyclodextrin,” J. Mater. Chem. B, Vol. 2, pp. 1699-1705, 2014. Published, 04/2014.
  • Li Yan, Anthony P Raphael, Xiaoyue Zhu, Beilei Wang, Wei Chen, Tao Tang, Yan Deng, Himanshu J Sant, Guangyu Zhu, Kwong Wai Choy, Bruce K Gale, Tarl W Prow, Xianfeng Chen, “Nanocomposite strengthened dissolving microneedles for improved transdermal delivery to human skin.” Advanced Healthcare Materials,Vol.;3(4), pp. 555-564, April 2014.. DOI: 10.1002/adhm.201300312. Published, 04/2014.
  • Cody Gehrke, Huizhong Li, Himanshu Sant, Bruce Gale and Jay Agarwal, “Design, Fabrication and Testing of a Novel Vascular Coupling Device,” J. Biomed. Microdev., Vol. 16, pp. 173-180, 2014. Published, 01/2014.
  • Tonguc O. Tasci, William. P. Johnson, Diego. P. Fernandez, Eliana. Manangon, Bruce. K. Gale, “Biased Cyclical Electrical Field Flow Fractionation for Separation of Sub 50 nm Particles,” Anal. Chem., Vol. 85, No. 23, pp. 11225-11232, December 3, 2013. Published, 12/2013.
  • Huizhong Li, Cody Gehrke, Himanshu Sant, Bruce K. Gale, Jay Agarwal, “A novel arterial coupler for microvascular surgery,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Harikrishnan Jayamohan, York R. Smith, Bruce K. Gale, Manoranjan Misra, Swomitra K. Mohanty, “Platinum functionalized titania nanotube array sensor for detection of trichloroethylene in water,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Cady Lancaster, Aixiang Liu, Curtis Sudbury, Bruce K. Gale, Jennifer Shumaker-Parry, “Atomic layer deposition of Al2O3 on plasmonic nanostructures for surface chemistry and multiplex analysis,” in Proc. of NanoUtah 2013, Salt Lake City, UT, October 10-11, 2013. Published, 10/2013.
  • Huizhong Li, Harikrishnan Jayamohan, Christopher Lambert, Swomitra Mohanty and Bruce K. Gale, “Automated Whole Blood Processing With A Portable Microfluidic Device For Point-Of-Care Diagnosis,” in Proc. of MicroTAS 2013, Freiburg, Germany, October 27 –31, 2013, pp. 1758-1760. Published, 10/2013.
  • Russell C. Reid, Fabien Giroud, Shelley D. Minteer, Bruce K. Gale, “Enzymatic Biofuel Cell with a Flow-Through Toray Paper Bioanode for Improved Fuel Utilization,” J. Electrochem. Soc., Vol. 160, No. 9, pp. H612-H619, 2013. Published, 09/2013.
  • Huizhong Li, Cody Gehrke, Himanshu Sant, Bruce K. Gale, Jayant Agarwal, “An Implantable Vascular Coupling Device for End-to-End Anastomosis,” in Proc. of The BMES 2013 Annual Meeting, Seattle, Washington, USA, September, 2013. Published, 09/2013.
  • Keng-Min Lin, Bruce Gale, Himanshu Sant, Jill Shea, William Sanders, Christi Terry and Jay Agarwal. “BSA-Filled PLGA nerve conduits for potential applications in nerve regeneration,” in Proc. of The BMES 2013 Annual Meeting, Seattle, Washington, USA, September, 2013. Published, 09/2013.
  • Jungkyu Kim, John Elsnab, Cody Gehrke, Jun Li, Bruce K. Gale, “Microfluidic Integrated Multi-walled Carbon Nanotube (MWCNT) Sensor for Electrochemical Nucleic Acid Concentration Measurement,” Sens. Act. B: Chemical., Vol. 185, pp. 370-376, August 2013. Published, 08/2013.
  • Tonguc Onur Tasci, William. Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “Utilization of Biased Voltage Waveforms for High Resolution Cyclical Electrical Field Flow Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “External Electrical Circuits for High Resolution Cyclical Electrical Field Flow Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Bruce K. Gale, “Magnetic Field Flow Fractionation Using Linear Halbach Arrays,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Eliana Manangon, Diego. P. Fernandez, Bruce K. Gale, Tonguc Onur Tasci, William Paul Johnson, “Mass Recoveries in Nano- to Micro-Particle Analysis of Environmental Samples Via Flow Field Flow Fractionation-Inductively Coupled Plasma Mass Spectrometry,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Eliana Manangon, Bruce K. Gale, “Computer Modeling of the Electrical Field Flow Fractionation Systems,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Tonguc Onur Tasci, William Paul Johnson, Diego. P. Fernandez, Himanshu J. Sant, Christopher J. Lambert, Eliana Manangon, Bruce K. Gale, “Continuous Separation of Nanoparticles by Cyclical Electrical Split Flow Thin Fractionation,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • Kevin E. Petersen, Eliana Manangon, Joshua L. Hood, Diego P. Fernandez, William P. Johnson, Bruce K. Gale, “Separation of Melanoma Exosomes and Microparticles with As-FlFFF,” in Proc. of 16th International Symposium on Field-and Flow-based Separation, Pau, France, June 30-July 4, 2013. Published, 07/2013.
  • T. O. Tasci, C. J. Lambert, W. P. Johnson, B. K. Gale, "A Magnetic Particle Micromixer,” in Proc. of Frontiers in BioMagnetic Particles, Telluride, CO, USA, June 2-5, 2013. Published, 06/2013.
  • T. O. Tasci, W. P. Johnson, B. K. Gale, "Particle Based Model For A Cyclical Magnetic Field Flow Fractionation System,” in Proc. of Frontiers in BioMagnetic Particles, Telluride, CO, USA, June 2-5, 2013. Published, 06/2013.
  • G.T. Carling, X. Diaz, M. Ponce, L. Perez, L. Nasimba, E. Pazmino, A. Rudd, S. Merugu, D.P. Fernandez, B.K. Gale, W.P. Johnson, “Particulate and dissolved trace element concentrations in three southern Ecuador rivers impacted by artisanal gold mining,” Water, Air, and Soil Pollution, Vol. 224, No. 2, 2013. Published, 05/2013.
  • Valentin Romanov, Adam Miles, Bruce Gale, Josh Eckman, Benjamin Brooks, “Flow Printingfor Fluorescent Microarray Applications,” in Proc. of 50th Annual Rocky Mountain Bioengineering Symposium & 50th International ISA Biomedical Sciences Instrumentation Symposium 2013, Colorado Springs, Colorado, USA, 5-7 April 2013, pp. 118-124. Published, 04/2013.
  • Valentin Romanov, Bruce Gale, Josh Eckman, Adam Miles, Benjamin Brooks, “Spot Morphology In Protein Microarrays,” in Proc. of 50th Annual Rocky Mountain Bioengineering Symposium & 50th International ISA Biomedical Sciences Instrumentation Symposium 2013, Colorado Springs, Colorado, USA, 5-7 April 2013, pp. 25-32. Published, 04/2013.
  • Bruce K. Gale, “Spinning Disk Platform for Digital PCR,” at Molecular Med Tri-con 2013, February 11, 2013, San Francisco, CA. Published, 02/11/2013.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, and B. K. Gale, “Separation of Magnetic Nanoparticles by Cyclical Electrical Field Flow Fractionation,” IEEE Trans. On Magnetics, Vol. 49, No. 1, pp. 331-335, 2013. Published, 01/2013.
  • Nathan Gooch, Randon Michael Burr, Dolly J. Holt, Bruce Gale, and Balamurali Ambati, “Design and in Vitro Biocompatibility of a Novel Ocular Drug Delivery Device,” J. Funct. Biomater. Vol. 4(1), pp. 14-27, doi:10.3390/jfb4010014, 2013. Published, 01/2013.
  • Harikrishnan Jayamohan, Himanshu Sant, York Smith, Swomitra K. Mohanty, Manoranjan Misra, Bruce K. Gale, “Ordered carbonized titania nanotube based electrochemical detection of hemoglobin,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 38. Published, 10/12/2012.
  • Kevin E. Petersen, Hyun-Tae Kim, Qingbo Guo, Hanseup Kim, Bruce Gale, “A valve-less electrostatic gas micropump with a peristaltic movement of a single zipper electrode,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 40. Published, 10/12/2012.
  • Russell Reid, Shelley Minteer, Fabien Giroud, Bruce Gale, “A flow-through microfluidic biofuel cell,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 44. Published, 10/12/2012.
  • Jesus Arellano, Chieh-Hsiang Yang Bruce K. Gale, Margit Janat-Amsbury, Spencer B. Bremer, Naveen Rathi, “Development of continuous flow microspotter for high-throughput drug screening and cytotoxicity evaluation,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 33. Published, 10/12/2012.
  • Lucia E. Manangon, Onur T. Tasci, Diego P. Fernandez, Bruce K. Gale, William P. Johnson, “Fractionation of size distributed samples by asymmetric flow field flow fractionation coupled online to light scattering and inductively coupled plasma mass spectrometry detectors,” in Proc. of NanoUtah 2012, Salt Lake City, UT, October 11-12, 2012, pp. 44. Published, 10/12/2012.
  • Keng-Min Lin, Himanshu J. Sant, Balamurali K. Ambati and Bruce K. Gale, “Intraocular Pressure Sensors: New Approaches For Real-Time Intraocular Pressure Measurement Using A Purely Microfluidic Chip,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • T. O. Tasci, C. J. Lambert, H. J. Sant, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Investigation Of The Channel Height On The Separation Efficiency Of An Electrical Field Flow Fractionation System,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • Raheel Samuel, Colin Thacker, Andres Villu Maricq, Bruce K. Gale, “Simple And Low-Cost Fabrication Protocol For Producing 100’s Of Pneumatic Microvalves In All-PDMS Substrates For Microfluidics Research,” in Proc. of MicroTAS 2012, Okinawa, Japan, October 28 – November 1, 2012. Published, 10/2012.
  • Keng-Min Lin, Himanshu J. Sant, Bruce K. Gale, and Jayant P. Agarwal, “New Approaches to Bridge Nerve Gaps: Development of a Novel Drug-Delivering Nerve Conduit,” in Proc. Of EMBC'12, San Diego, CA, August 28- September 1, 2012. Published, 08/28/2012.
  • Rahul Kolekar, Daniel Torgerson, John Viner, Bruce Gale and Tim Ameel, “Depth measurement in fully enclosed microchannels using laser interferometry,” Meas. Sci. Technol. Vol. 23, pp. 087004, 2012. Published, 08/2012.
  • Keng-Min Lin, Himanshu J. Sant, Jayant Agarwal and Bruce K. Gale, “New approaches to bridge nerve gaps: Development of a novel drug-delivering nerve conduit,” 34th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (IEEE EMBS). August, 2012. Paper WeB 15.7. Published, 08/2012.
  • Harikrishnan Jayamohan, Himanshu J. Sant, and Bruce K. Gale, “Applications of Microfluidics for Molecular Diagnostics,” in Microfluidic Diagnostics: Methods and Protocols, Volume 2: Application Protocols and Commercialization, Colin D. Mansfield and Gareth Jenkins, eds., Humana Press: New York, 2012. Published, 06/2012.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Cyclical Magnetic Field Flow Fractionation for the Separation of Magnetic Nanoparticles”, in Proc. of 9th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Minneapolis, MN, May 22-26, 2012. Published, 05/22/2012.
  • T. O. Tasci, E. Manangon, D. P. Fernandez, W. P. Johnson, B. K. Gale, “Cyclical Electrical Field Flow Fractionation for the Separation of Magnetic Nanoparticles”, in Proc. of 9th International Conference on the Scientific and Clinical Applications of Magnetic Carriers, Minneapolis, MN, May 22-26, 2012. Published, 05/22/2012.
  • Himanshu J. Sant and Bruce K. Gale, “Optimization and Characterization of a Microscale Thermal Field-Flow Fractionation System,” Sensors and Actuators B: Chemical, Vol. 162, No. 1, pp. 223-228, 2012. Published, 05/2012.
  • Himanshu J Sant and Bruce K. Gale, “Characterization Of A Microscale Thermal-Electrical Field-Flow Fractionation System,” Journal of Chromatography A, Vol. 1225, pp. 174-181, 2012. . Published, 04/2012.
  • Srinivas Merugu, Himanshu J. Sant and Bruce K. Gale, “Diffusion Split-Flow Thin Cell (SPLITT) System for protein separations,” Journal of Chromatography B, Vol. 902, pp. 78-83, 2012. Published, 04/2012.
  • T. Onur Tasci, William.P. Johnson, Bruce K. Gale. “Cyclical Magnetic Field Flow Fractionation”. J. Appl. Phys. Vol. 111, pp. 07D128, 2012. Published, 04/2012.
  • Siddharth Chakravarty, Himanshu Sant, Colin Fergusson, and Bruce K. Gale, “Characterization of polymerized liposomes using a combination of normal and cyclical electrical field flow fractionation,” Anal. Chem., Vol. 84, pp. 8323-8329, 2012. Published, 03/2012.
  • Wilaiwan Somchue, Atitaya Siripinyanond and Bruce K. Gale, “Electrical Field-Flow Fractionation for Metal Nanoparticles Characterization,” Anal. Chem, Vol. 84, pp. 4993-4998, 2012. Published, 03/2012.
  • Douglas Anjewierden, Gregory A. Liddiard, and Bruce K. Gale, “An electrostatic microvalve for pneumatic control of microfluidic systems,” J. Micromech. Microeng. Vol. 22, pp. 025019 (9pp), 2012. Published, 02/2012.
  • Srinivas Merugu, Himanshu J. Sant, and Bruce K. Gale, “A novel method for effective field measurements in electrical field-flow fractionation,” Electrophoresis, Vol. 33, pp. 1040–1047, 2012. Published, 02/2012.
  • Jungkyu Kim, Michael A. Johnson, Parker Hill, and Bruce K. Gale, “A microfluidic nucleic acid extraction system with both disposable and reusable components,” J. Micromech. Microeng. Vol. 22, pp. 015007 (9pp), 2012. Published, 01/2012.
  • Himanshu J. Sant, Michael Johnson, and Bruce K. Gale, “Integrated Microfluidics For Serotype Identification Of Foot-And- Mouth-Disease Virus,” in Proc. of MicroTAS 2011, Seattle, WA, USA, October 2-6, 2011, pp. 2007-2009. Published, 10/2011.
  • Rohit Sharma and Bruce K. Gale, “Electrochemical Quantification of DNA Using Aluminum Oxide Membranes,” in Proc. of Eurosensors XXV, September 4-7, 2011, Athens, Greece, pp. 1578-1581. Published, 09/2011.
  • Raheel Samuel, Himanshu J Sant, Fangxiang Jiao, Chris R Johnson and Bruce K Gale, ‘Microfluidic laminate-based phantom for diffusion tensor-magnetic resonance imaging,” J. Micromech. Microeng. Vol. 21, pp. 095027 (11pp), 2011. Published, 08/2011.
  • Julien Gigault , Bruce K. Gale , Isabelle Le Hécho , and Gaëtane Lespes, “Nanoparticle characterization by Cyclical Electrical Field-Flow Fractionation, Anal. Chem. Vol. 83, No. 17, p 6565-6572, 2011. DOI: 10.1021/ac2008948. Published, 08/2011.
  • Balamurali K. Ambati, Gilbert Wong, Griffin J. Jardine, Bruce Gale and John Elsnab, “Endocapsular Carousel Technique Phacoemulsification,” Journal of Cataract & Refractive Surgery, Vol. 37, No. 3, pp. 433-437, 2011. Published, 02/2011.
  • Raheel Samuel, Himanshu Jayant Sant, Fangxiang Jiao, Christopher R. Johnson, and Bruce K. Gale, “Fabrication of a MRI Standardization Device From Stacking Highly Patterned Thin PDMS Layers,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 744a. Published, 11/2010.
  • Keng-Min Lin, Corey J. Bishop, Himanshu J. Sant, Balamurali K. Ambati, and Bruce K. Gale, “Refilling Mechanism to Stabilize a Free-Floating Intraocular Capsule Drug Ring (CDR),” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 568v. Published, 11/2010.
  • Michael A. Johnson, Jungkyu Kim, Angela Williams, and Bruce K. Gale, “A Fully Automated Microfluidic Platform for Nucleic Acid Extraction,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 258b. Published, 11/2010.
  • Daniel Torgerson, Rahul Kolekar, Bruce Gale, and Tim Ameel, “Minor Losses In Rectangular Xurographic Microchannels,” in Proceedings of the ASME International Mechanical Engineering Conference & Exposition (IMECE2010), November 12-18, 2010, Vancouver, British Columbia, Canada, paper 39401 (10 pages). Published, 11/2010.
  • Himanshu Jayant Sant, Scott Sundberg, Erik Liddiard, Michael A. Johnson, and Bruce K. Gale, “Integrated Microfluidics for Serotype Identification of Foot and Mouth Disease Virus,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314f. Published, 11/2010.
  • Venu M. Arremsetty and Bruce K Gale, “Asymmetrical Cross-Flow Based Split Thin Cell Fractionation,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314g. Published, 11/2010.
  • Michael A. Johnson, Jungkyu Kim, Angela Williams, and Bruce K. Gale, “A Programmable Microfluidic System for Selective RNA or DNA Extraction From Various Raw Biological Sample,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314a. Published, 11/2010.
  • Greg A. Liddiard and Bruce K. Gale, “Pneumatically Controlled 32 Channel Scalable Disposable Microfluidic Sample Handling Device with Integrated Metering, Mixing, and Demultiplexing,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 258a. Published, 11/2010.
  • Bruce K. Gale, “Lessons Learned by An Entrepreneurial Minded University Professor On the Creation of New Companies,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 287c. Published, 11/2010.
  • Greg A. Liddiard, Erik Liddiard, and Bruce K. Gale, “Pneumatically Driven 16 Channel Disposable Nucleic Acid Filter Device with Integrated Demultiplexing and Multiplexing,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314d. Published, 11/2010.
  • Michael A. Johnson, Erik Liddiard, and Bruce K. Gale, “A Masked Corona Discharge Method for Selective Bonding in PDMS for Microfluidic Applications,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314i. Published, 11/2010.
  • Erik Liddiard, Himanshu Jayant Sant, Frederic Horndli, and Bruce K. Gale, “Measurement of Muscle Force in C. Elegans Worm Using Microfluidics,” in Proc. of AICHE 2010, Salt Lake City, Utah, November 7-12, 2010, paper 314h. Published, 11/2010.
  • Catherine Maltbie, Ian Papautsky, Suzanne van den Hoogenhof, David Eddington, Bruce Gale, Jin-Woo Choi, Glenn Walker, “Expanding the introduction of microfluidics through a problem-based laboratory course to multiple engineering disciplines at five universities,” IEEE Frontiers in Education Conference (FIE 2010), Washington DC, October 27 - 30, 2010, Paper S2F-6. Published, 10/2010.
  • Raheel Samuel, Himanshu J. Sant, Fangxiang Jiao, Christopher R. Johnson, and Bruce K. Gale, “Fabrication Of A MRI Standardization Device By Stacking Highly Patterned Thin PDMS Layers,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 1901-1903. Published, 10/2010.
  • Himanshu Sant, Scott Sundberg, Adam Miles, Michael Johnson, Erik Liddiard, and Bruce Gale, “Integrated Microfluidics For Serotype Identification Of Foot And Mouth Disease Virus,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 1832-1834. Published, 10/2010.
  • Michael Johnson, Jungkyu Kim, Angela Williams, and Bruce Gale, “A Programmable Microfluidic System For Selective RNA Or DNA Extraction From Various Raw Biological Samples,” in Proc. of MicroTAS 2010, Groningen, Netherlands, October 3-7, 2010, pp. 387-389. Published, 10/2010.
  • Catherine Maltbie, Ian Papautsky, Suzanne van den Hoogenhof, David Eddington, Bruce Gale, Jin-Woo Choi, Glenn Walker, “Expanding the introduction of microfluidics through a problem-based laboratory course to multiple engineering disciplines at five universities,” IEEE Frontiers in Education Conference (FIE 2010), Washington DC, October 27 - 30, 2010, Paper S2F-6. Published, 10/2010.
  • Merugu Srinivas, Himanshu Sant, and Bruce K. Gale, “Optimization of Cyclical Electrical Field Flow Fractionation,” Electrophoresis, Vol. 31 (20), pp. 3372-3379, 2010. Published, 08/2010.
  • Himanshu J. Sant, Tammy Ho, and Bruce K. Gale, “An In situ Heater for a Phase-Change-Material-based Actuation System,” JMM. Vol. 20, pp. 085039 (7pp), 2010. Published, 06/2010.
  • T. O. Tasci, A. Arat, E. Atalar, B. Gale, “Utilization of AC and DC Magnetic Fields for Focused Magnetic Fluid Hyperthermia and Magnetic Particle Fractionation,” in Proc. of 8th International Conference on the Scientific and Clinical Applications of Magnetic Carriers - Rostock, Germany, May 25-29, 2010, paper 194. Published, 05/2010.
  • Jitae Kim, Michael Mauk, Dafeng Chen, Jungkyu Kim, Bruce Gale, and Haim H. Bau, “A PCR Reactor With an Integrated Alumina Isolation Membrane,” Analyst, Vol. 135, pp. 2408–2414, 2010. Published, 05/2010.
  • Jungkyu Kim, Adam Miles, and Bruce K. Gale, “Improved biomolecule microarrays by printing on nanoporous aluminum oxide using a continuous-flow microspotter,” Small, Vol. 6, No. 13, pp. 1415–1421, 2010. Published, 05/2010.
  • Guang Yan, Kevin S. Warner, Jie Zhang, Sanjay Sharma, and Bruce K. Gale, “Evaluation needle length and density of microneedle arrays in the pretreatment of skin for transdermal drug delivery,” International Journal of Pharmaceutics, Vol. 391, pp. 7-12, 2010. Published, 04/2010.
  • Danny Blanchard, Phil Ligrani, Bruce Gale, “Slip Due to Surface Roughness for a Newtonian Liquid in a Viscous Micro-Scale Disk Pump,” Physics of Fluids, Vol. 22, No. 5, pp. 052002 (15 pgs), 2010. Published, 04/2010.
  • Sarah Molokhia, Himanshu J Sant; Jacquelyn M Simonis; Corey J Bishop; R. Michael Burr; Bruce K Gale; and Balamurali K Ambati, “The Capsule Drug Device: Novel Approach for Drug Delivery to the Eye,” Vision Research, Vol. 50, No. 7, pp. 680-685, 2010. Published, 02/2010.
  • Scott Sundberg, Carl Wittwer, Chao Gao, and Bruce Gale, “Spinning Disc Platform for Microfluidic Digital PCR,” Anal. Chem, Vol. 82, pp. 1546-1550, 2010. Published, 02/2010.
  • Jungkyu Kim, John Elsnab, Michael Johnson, Bruce K. Gale, “Sample to Answer: A Fully Integrated Nucleic Acid Identification System For Bacteria Monitoring,” in Proc. Of SPIE: Microfluidics, BioMEMS, and Medical Microsystems VIII, San Francisco, CA, January 23-28, 2010, Vol. 7593, pp. 75930S, 2010. doi: 10.1117/12.844856. Published, 01/2010.
  • Jianping Liu, Mark A. Eddings, Rostislav Bukasov, Bruce K. Gale, Jennifer S. Shumaker-Parry, “In Situ Microarray Fabrication and Analysis Using a Microfluidic Flow Cell Array Integrated with Surface Plasmon Resonance Microscopy,” Anal. Chem., Vol. 81, No. 11, pp 4296–4301, 2009. Published, 2009.
  • Daniel A. Bartholomeusz, Ronald W. Boutté and Bruce K. Gale. “Xurography: Microfluidic Prototyping with a Cutting Plotter,” in Lab-on-a-Chip Technology: Fabrication and Microfluidics., Keith E. Herold and Avraham Rasooly, eds. Caister Academic Press: Norwich, UK, 2009. Published, 2009.
  • Jungkyu Kim and Bruce K. Gale, “Rapid prototyping of microfluidic systems using a PDMS/polymer tape composite,” Lab. Chip, Vol. 9, pp. 1290-1293, 2009. Published, 2009.
  • Niel Crews, Carl Wittwer, Jesse Montgomery, Robert Pryor, Bruce K. Gale, “DNA Melting Analysis for Genotyping and Variant Scanning,” Anal. Chem. Vol. 81, No. 6, pp. 2053-2058, 2009. Published, 2009.
  • Jungkyu Kim, Michael Junkin, Deok-Ho Kim, Seunglee Kwon, Young Shik Shin, Pak Kin Wong, and Bruce K. Gale, “Applications, Techniques, and Microfluidic Interfacing for Nanoscale Biosensing,” Microfluidics and Nanofluidics, Vol. 7, No. 2, pp. 149-167, 2009. Published, 2009.
  • Ryan Sincic, David A. Chang-yen, Louis Barrows, Bruce K. Gale, “Parallel Determination of Phenotypic Cytotoxicity with a Micropattern of Mutant Cell Lines,” Biomed. Microdev., Vol. 11, No. 2, pp. 443-452, 2009. Published, 2009.
  • Mark A. Eddings, Josh W. Eckman, Carlos A. Arana, John E. Connolly, Bruce K. Gale, and David G. Myszka, “Spot-and-Hop Interspot Referencing for Surface Plasmon Resonance Imaging Using a Three-Dimensional Microfluidic Flow Cell Array,” Anal. Biochem., Vol. 385, No. 2, pp. 309-313, 2009. Published, 2009.
  • Rebecca L. Rich, Adam R. Miles, Bruce K. Gale, and David G. Myszka, “Detergent screening of a GPCR using serial and array biosensor technologies,” Anal. Biochem. Vol. 386, No. 1, pp. 98-104, 2009. Published, 2009.
  • Jungkyu Kim, Michael Johnson, Parker Hill and Bruce K. Gale, “Microfluidic sample preparation: cell lysis and nucleic acid purification,” Integr. Biol., Vol. 1, No. 10, pp. 574 – 586, 2009. Published, 2009.
  • James R. Joubert, Kathryn A. Smith, Erin Johnson, John P. Keogh, Vicki H. Wysocki, Bruce K. Gale, John C. Conboy, and S. Scott Saavedra, “Stable, ligand-doped, poly(bis-SorbPC) lipid bilayer arrays for protein binding and detection,” ACS Applied Materials and Interfaces, Vol. 1, No. 6, pp. 1310-1315, 2009. Published, 2009.
  • Michael Johnson, Greg Liddiard, Mark Eddings, and Bruce Gale, “Bubble inclusion and removal using PDMS membrane-based gas permeation for applications in pumping, valving, and mixing in microfluidic devices,” J. Micromech. Microeng., Vol. 9, pp. 095011 (9 pp), 2009. Published, 2009.
  • Himanshu J. Sant and Bruce K. Gale, “Flexible fabrication, packaging, and detection approach for microscale chromatography systems,” Sens. Act. B, Vol. 141, No. 1, pp. 316-321, 2009. Published, 2009.
  • Sriram Natarajan, Andrew Hatch, David Myszka, and Bruce Gale, “Optimal Conditions for Protein Array Deposition using a Continuous Flow Microspotter,” Anal. Chem., Vol. 80, No. 22, pp. 8561-8567, 2008. Published, 2008.
  • Mark A. Eddings, Michael A. Johnson, and Bruce K. Gale, “Determining the optimal PDMS-PDMS bonding technique for microfluidic devices, J. Micromech. Microeng. Vol. 18, pp. 067001 (1-4), 2008. Published, 2008.
  • Niel Crews, Carl Wittwer, Robert Palais, and Bruce Gale, “Product Differentiation during Continuous-Flow Thermal Gradient PCR,” Lab. Chip, Vol. 8, pp. 919 - 924, 2008. Published, 2008.
  • Sriram Natarajan, David Chang-Yen, and Bruce Gale, “Large-area, high-aspect-ratio SU-8 molds for fabrication of PDMS microfluidic devices,” J. Micromech. Microeng. Vol. 18, 045021, 2008. Published, 2008.
  • Niel Crews, Carl Wittwer, and Bruce Gale, “Thermal Gradient PCR in a Continuous-Flow Microchip,” Biomed. Microdevices, Vol. 10, No. 2, 2008. Published, 2008.
  • Sriram Natarajan, Phini S. Katsamba, Adam Miles, Josh Eckman, Giuseppe A. Papalia, Rebecca L. Rich, Bruce Gale, David G. Myszka, “Continuous-flow microfluidic printing of proteins for array-based applications including surface plasmon resonance imaging,” Anal. Biochem. Vol. 373, pp. 141-146, 2008. Published, 2008.
  • Niel Crews, Timothy A. Ameel, Carl Wittwer, and Bruce Gale, “Flow-Induced Thermal Effects on Spatial DNA Melting,” Lab. Chip, Vol. 8, pp. 1922-1929, 2008. Published, 2008.
  • Mark A. Eddings, Adam Miles, Josh Eckman, Jungkyu Kim, Rebecca L. Rich, Bruce K. Gale, and David Myszka, “Improved continuous-flow print head for micro-array deposition,” Anal. Biochem,. Vol. 382, No. 1, pp. 55-59, 2008. Published, 2008.
  • Jungkyu Kim and Bruce K. Gale, “Quantitative and qualitative analysis of a microfluidic DNA extraction system using a nanoporous AlOx membrane,” Lab. Chip, Vol. 8, pp. 1516 - 1523, 2008. Published, 2008.
  • Kathryn A. Smith, Bruce K. Gale, John C. Conboy, “Micropatterned fluid lipid bilayer array,” Anal. Chem. Vol. 80, No. 21, pp. 7980-7987, 2008. Published, 2008.
  • Bruce K. Gale, Mark A. Eddings, Scott O. Sundberg, Andrew Hatch, JungKyu Kim, and Tammy Ho. “ Fabrication and packaging: Low-cost MEMS technologies,” in Comprehensive Microsystems, 1st Ed. Yogesh B. Gianchandani, Osamu Tabata, Hans Zappe, eds. Elsevier Amsterdam, 2008. Published, 2008.

Research Statement

I am primarily interested in biomedical applications of microfluidics. I have expertise in developing biosensors, microarrays, micropumps, and microneedles. We study manufacturing and design methods for these types of devices. I am interested in studying and developing micro- and nano- systems that have application in DNA, protein (proteomics), lipid, and cellular analysis as well as drug delivery, biowarfare agent detection, medical diagnostics, and drug discovery. I also have significant experience and expertise in nanoparticle separations using field flow fractionation.

Research Keywords

  • nanoparticle separations
  • microarrays
  • Proteins and Macromolecules
  • Nanotechnology
  • Nanoparticles
  • Microfluidics
  • Microelectromechanical Systems (MEMS)
  • Medical Device Engineering
  • High-Throughput Screening
  • Field Flow Fractionation
  • Drug Delivery Systems
  • DNA-protein interactions
  • Chemical Sensors
  • Biosensors
  • Bio-MEMS
  • Analytical Chemistry

Presentations

  • Brady Goenner, Scott Temple, Sebastian Zapata, Pierre Emmanuel-Gaillardon, Gregory Nordin, and Bruce K. Gale, “AN OPEN-SOURCE MICROFLUIDIC DESIGN AUTOMATION WORKFLOW FOR 3D PRINTING,” in Proc. Of MicroTAS 2023, Katowice, Poland, Pages T142.e, October 15-19, 2023. Conference Paper, Refereed, Presented, 10/15/2023.
  • Brady L. Goenner, Matt D. Nelson, and Bruce K. Gale, “UTILIZING CHATGPT TO ASSIST CAD FOR MICROFLUIDIC DEVICES,” in Proc. Of MicroTAS 2023, Katowice, Poland, Pages W124.d, October 15-19, 2023. Conference Paper, Refereed, Presented, 10/15/2023.
  • Brady Goenner, Scott Temple, Pierre Emmanuel-Gaillardon, Gregory Nordin, and Bruce K. Gale, “ADAPTATION OF OPENROAD FOR MICROFLUIDIC DESIGN AUTOMATION,” in Proc. Of MicroTAS 2023, Katowice, Poland, Pages M216.h, October 15-19, 2023. Conference Paper, Refereed, Presented, 10/15/2023.
  • Utpal Saha, and Bruce K. Gale, “3D PRINTING AND DIELECTROPHORESIS FOR DROPLET CONTROL: TOWARDS A NEW ERA OF 3D PRINTED DROPLET MICROFLUIDICS “, in Proc. Of Micro Flow and interfacial Phenomena 2023 (uFIP), Evanston, IL, USA, Pg. P2.37, 18-21 June 2023. Conference Paper, Refereed, Presented, 06/18/2023.
  • Utpal Saha, James Baldwin-Brown and Bruce K. Gale, “SPERM RACETRACK: DESIGN, FABRICATION, AND TESTING OF A NOVEL MICROFLUIDIC DEVICE TO PASSIVELY SORT SPERM INTO GROUPS BASED ON MOTILITY “, in Proc. Of Micro Flow and interfacial Phenomena 2023 (uFIP), Evanston, IL, USA, Pg. P1.03, 18-21 June 2023. Conference Paper, Refereed, Presented, 06/18/2023.
  • Mohammadi Shad and Bruce K. Gale, “Design of a Cy-ElFFF device for ion retention and separation” in Proc. Of 21st International Symposium on Field-and Flow-based Separations, Riverside, CA, USA , 23 – 27 September, 2022. Conference Paper, Refereed, Presented, 09/27/2022.
  • Bruce Gale, "A Microfluidic, Automated Instrument To Improve Clinical Sperm Preparations," to Bay Area Microfluidics Network, October 7, 2021. Invited Talk/Keynote, Presented, 10/07/2021.
  • John Nelson, Dev Patel, Bruce Gale, Himanshu Sant, Jill Shea, Jay Agarwal, “Arterial Friction Fits,” in Proc. Of BMES 2020, October 14-17, 2020. Conference Paper, Refereed, Presented, 10/14/2020.
  • Mohammadi Shad, Farhad Shiri, Bruce K. Gale, “Isolation of ions using Electric Field Flow Fractionation (ElFFF)” in Proc. Of 20th International Symposium on Field-and Flow-based Separations, Vienna, Austria , 23 – 27 February, 2020. Conference Paper, Refereed, Presented, 02/25/2020.
  • Farhad Shiri, Bruce K. Gale, Himanshu Sant, Gina Bardi, Joshua Hood, Kevin Petersen, “Characterization and continuous processing of exosomes and oncosomes using Flow-Electrical Split-Flow Lateral Transport Thin (Fl-El-SPLITT)” in Proc. Of 20th International Symposium on Field-and Flow-based Separations, Vienna, Austria, 23 – 27 February, 2020. Conference Paper, Refereed, Presented, 02/25/2020.
  • Gale B (2019). Taking Microfluidics From Research Ideas to a Real Product. Proc. ASME 2019 International Mechanical Engineering Congress and Exposition (IMECE), November 10–14, 2019, Salt Lake City, Utah, USA. Invited Talk/Keynote, Presented, 11/10/2019.
  • Haidong Feng and Bruce K. Gale, “Sheathless Particle Separation In Viscoelastic Solution Utilizing Viscoelastic Flow Induced Secondary Flow In A Spiral Channel,” in Proc. Of MicroTAS 2018, Kaohsiung, Taiwan, Pages M197g, November 11-15, 2018. Conference Paper, Refereed, Presented, 11/11/2018.
    https://cbmsociety.org/wp-content/uploads/2018/11/...
  • Alexander R. Jafek, Haidong Feng, Dallin S. Broberg, Timothy G. Jenkins , Kenneth I. Aston , Bruce K. Gale , Raheel Samuel, “Motile Sperm Selection Using Dean Flow In A Spiral Channel,” in Proc. Of MicroTAS 2018, Kaohsiung, Taiwan, Pages T196g, November 11-15, 2018. Conference Paper, Refereed, Presented, 11/11/2018.
    https://cbmsociety.org/wp-content/uploads/2018/11/...
  • Kevin E. Petersen, Farhad Shiri, Bruce Gale, Himanshu Sant, Joshua Hood, Gina Bardi, “Separation of Oncosomes from Exosomes” in Proc. Of 18th International Symposium on Field-and Flow-based Separations, Columbia, SC, USA, , May 14-17, 2018. Conference Paper, Refereed, Presented, 05/14/2018.
  • Farhad Shiri, Kevin E. Petersen, Valentin Romanov, Qin Zou, Bruce K. Gale, “Separation of Virus like Particles using CyElFFF and AF4”, in Proc. Of 18th International Symposium on Field-and Flow-based Separations, Columbia, SC, USA, , May 14-17, 2018. Conference Paper, Refereed, Presented, 05/14/2018.
  • Farhad Shiri, Kevin E. Petersen (Coauthors), Himanshu Sant, Joshua Hood, Gina Bardi, Bruce Gale, “Separation of exosomes and oncosomes using continuous Asy-Fl-FFFF” in Proc. Of 18th International Symposium on Field-and Flow-based Separations, Columbia, SC, USA, , May 14-17, 2018. Conference Paper, Refereed, Presented, 05/14/2018.
  • Kevin E. Petersen, Farhad Shiri (Coauthors), Onur Tasci, Bruce Gale, “Theory, Experiment and Simulation of a new Flow Electrical FFF System” in Proc. Of 18th International Symposium on Field-and Flow-based Separations, Columbia, SC, USA, , May 14-17, 2018. Conference Paper, Refereed, Presented, 05/14/2018.
  • Bruce K. Gale, “The History and Applications of Electrical Field Flow Fractionation,” in Proc. Of 18th International Symposium on Field-and Flow-based Separations, Columbia, SC, USA, , May 14-17, 2018. Invited Talk/Keynote, Presented, 05/14/2018.
  • Bruce K. Gale, “The Future Of Diagnostic Labs: Lab-On-A-Chip,” 2018 Spring Seminar of the Utah Chapter of the American Society for Clinical Laboratory Science, Salt Lake City, UT, May 4, 2018. Invited Talk/Keynote, Presented, 05/04/2018.
  • 1. Chase Omana, Alex Jafek, and Bruce Gale, “Submillimeter Rapid Fabrication Techniques for Microfluidics,” in Proc. Utah Conference on Undergraduate Research 2018, Cedar City, UT, February 9-10, 2018. Other, Presented, 02/09/2018.
    https://www.suu.edu/ugrasp/ucur/schedule.html
  • Trevor Teerlink and Bruce Gale, “One Step Semen Preparation Device,” in Proc. Utah Conference on Undergraduate Research 2018, Cedar City, UT, February 9-10, 2018. Other, Presented, 02/09/2018.
    https://www.suu.edu/ugrasp/ucur/schedule.html
  • Hayden Brady, Sean Harbertson, Alex Jafek, Raheel Samuel, Bruce Gale, “Utilization of Fluid Dynamic Testing to Improve Fluid Transport on Microfluidic PCR Chips,” in Proc. Utah Conference on Undergraduate Research 2018, Cedar City, UT, February 9-10, 2018. Other, Presented, 02/09/2018.
    https://www.suu.edu/ugrasp/ucur/schedule.html
  • Sean Harbertson and Bruce Gale, “Micro Scale Filtration Using Spiral Channel Devices,” in Proc. Utah Conference on Undergraduate Research 2018, Cedar City, UT, February 9-10, 2018. Other, Presented, 02/09/2018.
    https://www.suu.edu/ugrasp/ucur/schedule.html
  • Gabriel Poulson and Bruce Gale, “Fabrication of Multi-material Microfluidic Devices,” in Proc. Utah Conference on Undergraduate Research 2018, Cedar City, UT, February 9-10, 2018. Other, Presented, 02/09/2018.
    https://www.suu.edu/ugrasp/ucur/schedule.html
  • Valentin Romanov, Bruce Kent Gale, Adam Frost, “Microfluidic Synthesis of Size and Lipid Asymmetry Controlled Biologically Relevant Nanoscale Liposomes,” in Proc. Of IMECE 2017, Tampa, FL, USA, November 3-9, 2017. Conference Paper, Refereed, Presented, 11/08/2017.
    http://online.flipbuilder.com/alic/dnid/mobile/ind...
  • Marzieh Chaharlang and Bruce Kent Gale, “Determination of the Optimialo Sperm Cell Alignment for Sperm Separation,” in Proc. Of IMECE 2017, Tampa, FL, USA, November 3-9, 2017. Conference Paper, Refereed, Presented, 11/08/2017.
    http://online.flipbuilder.com/alic/dnid/mobile/ind...
  • Christopher Lambert, Brianna Potter, Raheel Samuel, Bruce Gale, Josh Bonkowsky, “A rapid microfluidic device for genotyping of live zebrafish embryos,” in Proc. Of the 10th European Zebrafish Meeting (Zebrafish 2017), Budapest, Hungary, July 3-7, 2017. Other, Presented, 07/03/2017.
    http://zebrafish2017.org/accepted-posters/
  • Jiyoung Son, Bruce K. Gale, James M. Hotaling and Douglas T. Carrell, “Purification Of Sperm From High WBC Semen Samples Using A Spiral Channel,” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 248-249, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • H. Feng, M. Hockin, S. Zhang, H. Sant and B. K. Gale, “Cell Lysis And Chromosome Extraction In Microfluidic Pinched Flow Devices,” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 689-690, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • R. Samuel, A. Jafek, J. Trauba, K. Carney, R. Pryor, B. Gale, C. Wittwer, and K. Aston, “40 Cycle PCR Using Human Genomic DNA In Less Than 1 Minute On A Microfluidic Chip” in Proc. Of MicroTAS 2016, October 9-13, 2016, Dublin, Ireland, pp. 619-620, 2016. Conference Paper, Refereed, Presented, 10/2016.
  • Susan Wojtalewicz, Brett Davis, Pratima Labroo, Ching-wen Li, Jill Shea, Bruce Gale, Himanshu Sant, Jay Agarwal, “Localized FK506 Delivery System for Peripheral Nerve Repair,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Pratima Labroo, Isak Goodwin, Brett Davis, Kyle Edwards, Scott Ho, Himanshu Sant, Bruce Gale, Jill Shea, Jay Agarwal, “Effect Of NGF Delivering Conduit On Peripheral Nerve Regeneration,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Pratima Labroo, Ching-wen Li, Himanshu Sant, Bruce Gale, Jill Shea, Jay Agarwal , “Self Contained Bioreactor For Bone Regeneration,” in Proc. of BMES 2016, Minneapolis, MN, October 5-8, 2016. Other, Presented, 10/2016.
  • Farhad Shiri, Kevin E. Petersen, Bruce K. Gale, “EL-FFF Separation Of Nanoparticle Mixtures,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, P7. Other, Presented, 05/2016.
  • Kevin E. Petersen, Bruce K. Gale, Joshua L. Hood, Brody King, Farhad Shiri, Sam A. Wickline, “Separation Of Exosomes With Electrical Field Flow Fractionation,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, O22. Other, Presented, 05/2016.
  • Kevin E. Petersen, Brody King, Travis White, Farhad Shiri, Joshua L. Hood, Samuel A. Wickline, Bruce K. Gale, “Recent Advances In EL-SPLITT: A Flow Addition With Porous Electrode,” in Proc. Of FFF 2016, Dresden, Germany, May 22-26, 2016, P43. Other, Presented, 05/2016.
  • Bruce K. Gale and Kevin E. Petersen, “Exosome separation using electrical field flow fractionation and a new continuous SPLITT/FFF approach, in Proc. Of ACS 2016 Spring Meeting, March, 13, 2016, San Diego, CA, Paper ANYL 12, 2016. Invited Talk/Keynote, Presented, 03/13/2016.
  • Matt Hockin, Himanshu Jayant Sant, Mario Capecchi, Bruce K. Gale, “Dean flow fractionation of chromosomes,” in Proc. Of SPIE (Biomedical Optics), San Francisco, CA, February 13, 2016, paper 9705-1, 2016. Invited Talk/Keynote, Presented, 02/13/2016.
  • Pratima Labroo, Himanshu Sant, Scott Ho, Bruce Gale, Jill E. Shea and Jayant Agarwal, “Controlled Delivery of Growth Factors and Small Molecules for Peripheral Nerve Regeneration,” in Proc. Of AICHE, November 10, 2015, Salt Lake City, UT, Paper 437560, 2015. Conference Paper, Refereed, Presented, 11/10/2015.
  • Naveen Rathi, Nikki Davidoff, Ben Brooks, and Bruce K. Gale, “Using COMSOL to Simulate the Flow of Cells through a Continuous Flow Microfluidic Printing Device,” in Proc. Of NanoUtah 2015, October 15, 2015. Conference Paper, Refereed, Presented, 10/15/2015.
  • 1. Jesús Arellano, Taylor Howell, James Gammon, Sungpil Cho, Margit Janat-Amsbury, and Bruce K. Gale, “Utilization of a Microfluidic Flow Cell Array in the Implementation of a High-Throughput Drug Screening and Cytotoxicity Evaluation System,” in Proc. of BMES 2015, Tampa, FL, October 7-10, 2015. Conference Paper, Refereed, Presented, 10/10/2015.
  • Matt Hockin, Himanshu Jayant Sant, Mario Capecchi, Bruce K. Gale, “An Inertial Microfluidic Device for Rapid Purification of Chromosomes,” in Proc. Of RGJ 2015, Pattaya, Thailand, June 5, 2015. Invited Talk/Keynote, Presented, 06/05/2015.
  • Y. R. Smith, H. Jayamohan, L. Hansen, S. K. Mohanty, B. K. Gale, and M. Misra, “Microfluidic Photocatalytic Device Utilizing Anodized Titania Nanotube Arrays: Application and Simulation Validation,” in Proc. Of ECS 2015 Spring Meeting, May 24-28, 2015, Chicago, IL, paper 1995, 2015. Conference Paper, Refereed, Presented, 05/28/2015.
  • R. C. Reid, S. D. Minteer, and B. K. Gale, “Contact Lens Biofuel Cell Tested in Conditions Similar to Human Eyes,” in Proc. Of ECS 2015 Spring Meeting, May 24-28, 2015, Chicago, IL, paper 1709, 2015. Conference Paper, Refereed, Presented, 05/28/2015.
  • Jiyoung Son, Raheel Samuel, Kristin Murphy, Douglas Carrell, Bruce Gale, and James Hotaling, “Non-Motile Sperm Cell Separation Using A Spiral Channel,” in Proc. Of Andrology Society of America, Poster #99, April 18-21, 2015, Salt Lake City, UT, 2015. Conference Paper, Refereed, Presented, 04/18/2015.
  • R Samuel, B Gale, O Badamjav, K Murphy, T Jenkins, D Carrell, J Hotaling, “Microfluidic Sperm Trapping Chip for Processing Samples with Low Concentration for Assisted Reproductive Technology (ART) Therapies,” in Proc. Of SLAS 2015, February 9-11, 2015, Washington DC, 2015. Conference Paper, Refereed, Presented, 02/11/2015.
  • Talk Presented at Colorado State University. Other, Presented, 11/09/2013.
  • Talk at Louisiana Tech University. Other, Other, 01/31/2013.
  • Bruce K. Gale, Microfluidic Tools for PCR and Digital PCR , at Digital PCR - Applications and Advances, October 15-16, 2012, San Diego, CA. Invited Talk/Keynote, Presented, 10/15/2012.
  • Bruce K. Gale, “A Microfluidic Toolbox for Biomedical Applications,” in Proc. of Royal Golden Jubilee-Ph.D. Congress XIII, Pattaya, Chonburi, Thailand, April 6 – 8, 2012, pg. 82. Invited Talk/Keynote, Presented, 04/06/2012.
  • Presentation to Myriad Genetics on DNA analysis techniques. Other, Presented, 09/2011.
  • Presentation to IPREM in Pau, France on Field Flow Fractionation. Other, Presented, 06/2011.
  • Presentation to SLCC Nanoscience Symposium. Other, Presented, 04/2011.
  • Bruce Gale, Himanshu Sant, Srinivas Merugu, and William Johnson, “Microfluidic field flow fractionation of SPLITT techniques for nanoparticles and protein characterization and separation,” in Proc. of the 2010 International Chemical Congress of Pacific Basin Societies, Honolulu, Hawaii, December 15-20, 2010, paper 47. Invited Talk/Keynote, Presented, 12/2010.
  • Bruce K. Gale, “A Microfluidic Toolbox for Biomedical Applications,” at the 54th International Conference on Electron, Ion, and Photon Beam Technology and Nanofabrication (EIPBN 2010), Anchorage, AK, June 4, 2010. Invited Talk/Keynote, Presented, 05/2010.
  • S.A. Molokhia, H.J. Sant, M.C. Hanson, R.M. Burr, A.E. Poursaid, C.J. Bishop, J.M. Simonis, B.K. Gale, B.K. Ambati, “New Intraocular Drug Delivery Device,” ARVO 2009 Annual Meeting Fort Lauderdale, FL May 3-7, 2009. Conference Paper, Refereed, Other, 05/03/2009.
  • Scott O. Sundberg, Bruce K. Gale, and Carl T Wittwer, “Spinning disk platform for digital PCR,” in Proc. of the 41st Annual Oak Ridge Conference, Baltimore, MD, April 16-17, 2009. Conference Paper, Refereed, Presented, 2009.
  • Jungkyu Kim, Michael Johnson, Parker Hill, Rahul Sonkul, Jongwon Kim, Bruce K. Gale, “Integrated microfluidic RNA extraction system” in Proc. of the 5th Conference on Microtechnologies in Medicine and Biology (MMB), Quebec City, Quebec, Canada 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, Adam Miles, and Bruce K. Gale, Improved Protein Microarrays Using Continuous Flow Printing And A Nanoporous Substrate,” in Proc. of MicroTAS 2009, Jeju, Korea, November 1-5, 2009, pg. 1781-1783. Conference Paper, Refereed, Other, 2009.
  • Himanshu J. Sant, Srinivas Merugu, and Bruce K. Gale, “A Microscale Diffusional SPLITT System: Macromolecule Separations,” in Proc. of 14th International Symposium on Field-and Flow-based Separation, Rio, Patras, Greece, July 5-9, 2009. Conference Paper, Refereed, Presented, 2009.
  • Srinivas Merugu, Himanshu J. Sant, and Bruce K. Gale, “Optimization of Cyclical Electrical Field Flow Fractionation,” in Proc. of 14th International Symposium on Field-and Flow-based Separation, Rio, Patras, Greece, July 5-9, 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, John Elsnab, Michael Johnson, Prabhu Arumugam, Hua Chen, Rahul Sonkul, Cory Shorr, Cody Gehrke, Bruce K. Gale, “A fully integrated nucleic acid identification system for bacteria monitoring,” in Proc. of NanoUtah 2009, October 15, 2009. Conference Paper, Refereed, Other, 2009.
  • Jungkyu Kim, Rajesh Surapaneni, Bruce K. Gale :” Rapid prototyping of microfluidic systems using a PDMS/tape composite,” in Proc. of the 5th Conference on Microtechnologies in Medicine and Biology (MMB), Quebec City, Quebec, Canada 2009. Conference Paper, Refereed, Other, 2009.
  • Scott O. Sundberg, Carl Bruce K. Gale, and Carl T. Wittwer, “Spinning Disc Platform for Digital PCR,” Fourth Annual Mountain West Biomedical Engineering Conference, Park City, UT, September 5-6, 2008. Conference Paper, Presented, 09/06/2008.
  • Bruce K. Gale, “Printing of High Quality Protein and Lipid Microarrays Using a Continuous Flow Microspotter,” Joint 63rd Northwest / 21st Rocky Mountain Regional ACS Meeting, June 15-18, 2008. Conference Paper, Presented, 06/16/2008.
  • Mark A. Eddings, Adam Miles, Jianping Liu, David G. Myszka, Jennifer Shumaker-Parry, Josh W. Eckman, Gary Sams, Bruce K. Gale, “A Highly Parallel Flow Cell Enabling Multi-channel Sensing in Diagnostic Applications,” at Oak Ridge Conference (AACC), April 17-18, 2008. Invited Talk/Keynote, Presented, 04/18/2008.
  • Michael Johnson, Greg Liddiard, Mark Eddings, Bruce Gale, “Bubble Inclusion And Removal Using Pdms Membrane-Based Gas Permeation For Applications In Pumping And Mixing In Microfluidic Devices,” in Proc. of MicroTAS 2008, San Diego, CA, Oct. 12-16, 2008, pg. 1006-1008. Conference Paper, Other, 2008.
  • Scott O Sundberg, Bruce K. Gale, and Carl T. Wittwer, “Spinning Disc Platform for Digital PCR,” in Proc. of Association for Molecular Pathology 2008 Annual Meeting, October 29-November 2, 2008. Conference Paper, Other, 2008.

Research Groups

  • Harikrishnan Jayamohan, Postdoc. Mechanical Engineering. 07/01/2015 - 02/29/2016.
  • Christopher Lambert, Technician. 06/01/2014 - 08/15/2016.
  • Raheel Samuel, Postdoc. Mechanical Engineering/Andrology. 05/01/2014 - present.
  • Himanshu Sant, Research Professor. Mechanical Engineering. 07/01/2013 - present.
  • Wilaiwan Somchue, Visiting Student. 10/01/2010 - 05/15/2011.
  • Faris Ali, Technician. 09/01/2010 - 04/30/2011.
  • Julien Gigault, Visiting Student. 07/2010 - 10/15/2010.
  • Julian Soulacroix, Visiting Student. 05/01/2010 - 07/31/2010.
  • Merugu Srinivas, Postdoc. ECE. 10/01/2009 - 09/30/2010.
  • Himanshu Sant, Research Professor. BIoengineering. 09/2008 - present.

Research Equipment and Testing Expertise

  • Soft lithography, laser patterning, xurography, corona, rapid prototyping systems.

Geographical Regions of Interest

  • France
    Have established an exchange program and will be visiting this summer. Hosted two students from France in 2010. Spent 5 weeks working in Gaetane Lespes lab in Pau, France during June/July 2011.
  • India
    Fulbright Scholar in the Chennai area. Established microfluidics skills in the area.
  • Thailand
    Have had exchange student from Thailand working in my lab for 7 months and now have a joint publication. Will make a reciprocal visit in April 2012. Additional student arrived in November 2013. Finished in October 2014. Will visit again in June 2015.

Grants, Contracts & Research Gifts

  • HT Label-Free Screening and Kinetic Analysis of Small Molecules and Biologics (R44GM109738). PI: BROOKS, BENJAMIN DELBERT. Co-PI(s): BRUCE K GALE. National Institutes of Health, 2014 - 04/30/2016. Total project budget to date: $840,165.00
  • Peripheral Nerve Regeneraion with a Novel Drug-Delivering Nerve Conduit. PI: Jayant Agarwal. Co-PI(s): Bruce Gale, Jill Shea, Bala Ambati. DOD CDMRP, 10/01/2013 - 09/30/2016. Total project budget to date: $600,000.00

Patents

  • Methods and devices for connecting nerves (#10842494). Status: Issued. Inventors: Jayant P. Agarwal, Bruce Kent Gale, Himanshu Jayant Sant, Pratima Labroo, Jill Shea. File date 08/03/2018; Issue date 11/24/2020.