Presentations

• Bulaj G (2008) Discovery and Development of Analgesic Conotoxins that Block Sodium Channels, Vertex, May 7th, 2008, San Diego, CA. Invited Talk/Keynote, Presented, 2008.
• Bulaj G, Adkins Scholl E, Smith MD, Pruess T, Grussendorf E, Grussendof BR, White HS (2008) NAX-5055:Systemically Active Galanin Analog for the Treatment of Epilepsy and Pain, 9th EILAT Conference on New Antiepileptic Drugs (EILAT IX), June 15-19, Sitges, Spain. Invited Talk/Keynote, Presented, 2008.
• Bulaj G (2008) Engineering Anticonvulsant Neuropeptides for the Treatment of Epilepsy and Pain, September 25th, 2008, Arena Pharmaceuticals, San Diego, CA. Invited Talk/Keynote, Presented, 2008.
• Bulaj (2008) Discovery and Development of Conopeptide-Based Analgesics that Target Neuronal Subtypes of Sodium Channels, ACT2008, IBC Life Sciences Conference on Assays and Cellular Targets, September 24-26, 2008, San Diego, CA. Invited Talk/Keynote, Presented, 2008.
• Bulaj G (2008) Discovery and development of subtype-selective sodium channel blockers derived from venomous cone snails, Symposium on High-Throuput Screening for Neuroscience organized by the NIH-Molecular Libraries Program, Nov 14th, 2008, Washington, DC. Invited Talk/Keynote, Presented, 2008.
• Bulaj G (2008) Discovery and Development of Venom-Derived Sodium Channel Blockers as Therapeutics for Pain, Max-Delbrück-Center for Molecular Medicine, June 27th, 2008, Berlin, Germany . Invited Talk/Keynote, Presented, 2008.

Geographical Regions of Interest

• Europe
• Philippines

Publications

• Bulaj G, Green BR, Lee HK, Robertson CR, White K, Zhang L, Sochanska M, Flynn SP, Adkins Scholl E, Pruess TH, Smith MD, White HS (2008) Design, Synthesis and Characterization of High-Affinity, Systemically-Active Galanin Analogs with Potent Anticonvulsant Activities, J Med Chem, 51, 8038-47. Published, 2008.
• Walewska A, Skalicky JJ, Davis DR, Zhang MM, Lopez-Vera E, Watkins W, Han TS, Yoshikami D, Olivera BM, Bulaj G, (2008) NMR-Based Mapping of Disulfide Bridges in Cysteine-Rich Peptides: Application to the μ-Conotoxin SxIIIA, J Am Chem Soc, 130, 14280-86. Published, 2008.
• Yao S, Zhang MM, Yoshikami D, Azam L, Olivera BM, Bulaj G, Norton RS (2008) Structure, dynamics and selectivity of the sodium channel blocker μ-conotoxin SIIIA, Biochemistry, 47, 10940-49. Published, 2008.
• Bulaj G, (2008) Integrating the discovery pipeline for novel compounds targeting ion channels, Curr Opin Chem Biol, 12, 441-447. Published, 2008.
• Walewska A, Bulaj G, (2008) Mechanisms of the Oxidative Folding of Small, Disulfide-Rich Peptides, book chapter in Oxidative Folding of Proteins and Peptides (Ed. L. Moroder), Royal Chemical Society, 274-296. Published, 2008.
• Fiedler B, Zhang MM, Azam L, Bulaj G, Norton RS, Olivera BM, Buczek O, Yoshikami D (2008) Specificity, affinity and efficacy of iota-conotoxin RXIA, an agonist of voltage-gated sodium channels Na(V)1.2, 1.6 and 1.7. Biochem Pharmacol, 75, 2334-44. Published, 2008.
• Han TS, Teichert RW, Olivera BM, Bulaj G, (2008) Conus Venoms - A Rich Source of Peptide-Based Therapeutics, Curr Pharm Design,14, 2462-2479. Published, 2008.
• Lopez-Vera E, Walewska A, Skalicky JJ, Olivera BM, Bulaj G (2008) Role of Hydroxyprolines in the Oxidative Folding and Biological Activity of Conotoxins. Biochemistry 47, 1741-1751. Published, 2008.
• Gowd KH, Twede V, Watkins M, Krishnan KS, Teichert RW, Bulaj G, BM Olivera (2008) Conantokin-P, an Unusual Conantokin with a Long Disulfide Loop. Toxicon, 52, 203-13. Published, 2008.
• Bulaj G, Olivera BM (2008) Folding of Conotoxins: Formation of the Native Disulfide Bridges during Chemical Synthesis and Biosynthesis of Conus peptides. Antiox Redox Sign, 10:141-56. Published, 2008.
• Arturo O. Lluisma AO, López-Vera E, Bulaj G, Watkins M, Olivera BM (2008) Characterization of a novel ψ-conotoxin from Conus parius Reeve, Toxicon, 51:174-80. Published, 2008.