GRZEGORZ BULAJ portrait
  • Professor, Medicinal Chemistry
  • Adjunct Assistant Professor, Department Of Anesthesiology

Education

  • Ph.D., University of Wroclaw, Poland
  • M.Sc., Biochemistry, University of Wroclaw

Research Interests

To mitigate limitations of pharmaceutical drugs (e.g., non-adherence, drug-resistance, adverse effects, affordability) for epilepsy, pain, depression or cancer, our research is focused on creating digital therapeutics (mobile medical apps). Digital therapeutics are mobile apps which receive the FDA regulatory status of “software as a medical device” to treat specific disorders. To improve therapy outcomes, mobile medical apps can be combined with pharmaceutical drugs yielding drug-device combination products. The long-term goal of our research is to develop drug-device combination therapies which target chronic diseases at both pharmacological and behavioral levels.

Examples of our projects include:

1. Development of mobile medical apps for the treatment of epilepsy: https://www.frontiersin.org/articles/10.3389/fnhum.2018.00171/full

2. Development of music streaming as adjunct digital therapies for depression: https://www.frontiersin.org/articles/10.3389/fpubh.2016.00217/full

3. Development of a mobile game coupling physical exercise and empowerment for children with cancer undergoing chemotherapy: https://www.frontiersin.org/articles/10.3389/fped.2018.00069/full

4. Preclinical study of music-enhanced neuropharmacology as surrogate for advancing drug-digital combination therapies for chronic pain: https://www.frontiersin.org/articles/10.3389/fneur.2019.00277/full

5. Integration of pharmacotherapies with digital health technologies: https://www.frontiersin.org/articles/10.3389/fphar.2021.612602/full

6. Impact of digital interventions for pain on patient-centered pharmacy care https://www.frontiersin.org/articles/10.3389/fdgth.2022.884047/full