Research Statement
My laboratory research involves gene expression by endothelial cells (EC) under both basal and stressed conditions. The goal is to understand how stressed EC alter their function to allow development of vascular disease such as atherosclerosis. In particular, we focus on post-transcriptional and translational control of gene expression in EC.
Clinically, I am interested in outcomes research in patients with vascular disease as well as use of non-invasive imaging by the vascular laboratory to assess the status of arteries and veins.
Research Keywords
- Venous Thrombosis
- Vascular Ultrasound
- Vascular Surgical Procedures
- Vascular Diseases
- Translation, Genetic
- Translation
- Thrombosis
- Regulation of protein translation in endothelial cells
- RNA Processing, Post-Transcriptional
- Peripheral Vascular Diseases
- Molecular Genetic Aspects of Thrombosis
- Mesenteric Vascular Occlusion
- Mechanotransduction, Cellular
- Hypertension, Renovascular
- Graft Occlusion, Vascular
- Gene Expression Regulation
- Gene Expression
- Endothelium, Vascular
- Endothelial Mechanotransduction
- Endothelial Cells
- Endothelial Cell Biology
- Embolism and Thrombosis
- Carotid Artery Thrombosis
Languages
- English, fluent.