Publications

• E. Arehart & F. R. Adler (2023). A minimal model of learning: quantifying the cost and benefit of learning in changing environments. Proceedings of the Royal Society B. Vol. 290. Published, 08/2023.
• R. Emond & J. I. Griffiths, V. K. Grolmusz, A. Nath, J. Chen, E. F. Medina, R. S. Sousa, F. R. Synold, T. Adler, and A. H. Bild (2023). Cell facilitation promotes growth and survival under drug pressure in breast cancer. Nature Communications. Vol. 14. Published, 06/2023.
• K. Cuddington & K. C. Abbott, F. R. Adler, M. Aydeniz, R. Dale, L. J. Gross, A. Hastings, E. A. Hobson, V. A. Karatayev, A. Killion, et al. (2023). Challenges and opportunities to build quantitative self-confidence in biologists. BioScience. Vol. 73, 364-375. Published, 05/2023.
• A. Bukkuri & F. R. Adler (2023). Biomarkers or biotargets? using competition to lure cancer cells into evolutionary traps. Evolution, Medicine, and Public Health. Vol. 11, 264–276. Published, 05/2023.
• J. I. Griffiths & P. A. Cosgrove, E. M. Castaneda, A. Nath, J. Chen, F. R. Adler, J. T. Chang, Q. J. Khan, and A. H. Bild (2023). Cancer cells subvert fibroblast function to promote a growth factor enriched tumor microenvironment in endocrine therapy resistant ER+ breast cancer. Cancer Research. Vol. 83. Published, 04/2023.
• J. I. Griffiths & P. A. Cosgrove, E. M. Castaneda, A. Nath, J. Chen, F. R. Adler, J. T. Chang, Q. J. Khan, and A. H. Bild (2023). Cancer cell communication with macrophages prevents T cell activation during emergence of cell cycle therapy resistance. Cancer Research. Vol. 83. Published, 04/2023.
• F. R. Adler & A. R. Anderson, A. Bhushan, P. Bogdan, J. J. Bravo-Cordero, A. Brock, Y. Chen, E. Cukierman, K. E. DelGiorno, G. V. Denis, et al. (2023). Modeling collective cell behavior in cancer: Perspectives from an interdisciplinary conversation. Cell Systems. Vol. 14, 252-257. Published, 04/2023.
• E. Arehart & J. R. Reimer, and F. R. Adler (2023). Strategy maps: Generalised givingup densities for optimal foraging. Ecology Letters. Vol. 26, 398-410. Published, 03/2023.
• A. Beams & L. T. Keegan, F. R. Adler, M. H. Samore, K. Khader, and D. J. Toth. (2023). Are Staphylococcus aureus carrier types evidence of population heterogeneity?. American Journal of Epidemiology. Vol. 192, 455-466. Published, 02/2023.
• West, J. & F. Adler, J. Gallaher, M. Strobl, R. Brady-Nicholls, J. Brown, M. Roberson-Tessi, E. Kim, R. Noble, Y. Viossat, et al (2023). A survey of open questions in adaptive therapy: Bridging mathematics and clinical translation. Elife. Published, 01/09/2023.
• E. Arehart (2023). Strategy maps: Generalized giving-up densities for optimal foraging. Ecol. Letters. Published, 01/2023.
  https://pubmed.ncbi.nlm.nih.gov/36719341/
• A. B. Beams & L. T. Keegan, F. R. Adler, M. H. Samore, K. Khader, and D. J. A. Toth (2022). Staphylococcus aureus carrier types are not evidence of population heterogeneity. Am. J. Epidemiol. Published, 12/2022.
• J. R. Reimer & F. R. Adler, K. M. Golden, and A. Narayan (2022). Uncertainty quantification for ecological models with random parameters. Ecology Letters. Vol. 25, 2232-2244. Published, 06/2022.
  https://onlinelibrary.wiley.com/doi/pdf/10.1111/el...
• T. G. Liou & N. Argel, F. Asfour, P. S. Brown, B. A. Chatfield, D. R. Cox, C. L. Daines, D. Durham, J. B. Francis, B. Glover, et al. (2022). Associations of sputum biomarkers with clinical outcomes in people with cystic fibrosis. medRxiv. Published, 05/2022.
  https://www.medrxiv.org/content/10.1101/2022.05.25...
• F. R. Adler & S. R. Amend, C. J. Whelan, and E. Baratchart (2022). From ecology to cancer biology and back again. Frontiers in Ecology and Evolution. Vol. 9. Published, 02/2022.
  https://www.frontiersin.org/research-topics/15739/...
• T. G. Liou & F. R. Adler, B. C. Cahill, D. R. Cox, J. E. Cox, G. J. Grant, K. E. Hanson, S. C. Hartsell, N. D. Hatton, M. N. Helms, et al (2021). SARS-CoV-2 innate effector associations and viral load in early nasopharyngeal infection. Physiological Reports. Published, 11/2021.
• T. G. Liou & F. R. Adler, and N. D. Hatton (2021). The Uncertain Role of Corticosteroids in the Treatment of COVID-19. JAMA Internal Medicine. Vol. 181, 139-140. Published, 08/2021.
• A. Dunca & F. R. Adler (2021). Predicting molecular phenotypes with single cell RNA sequencing data: an assessment of unsupervised machine learning models. arXiv. Published, 08/2021.
• A. Bukkuri & F. R. Adler (2021). Viewing cancer through the lens of corruption: Using behavioral ecology to understand cancer. Frontiers in Ecology and Evolution. Vol. 9, 442. Published, 07/2021.
• C. K. Buhler & R. S. Terry, K. G. Link, and F. R. Adler (2021). Do mechanisms matter? comparing cancer treatment strategies across mathematical models and outcome objectives. Mathematical Biosciences and Engineering. Vol. 18, 6305– 6327. Published, 07/2021.
• J. I. Griffiths & J. Chen, P. A. Cosgrove, A. O’Dea, P. Sharma, C. Ma, M. Trivedi, K. Kalinsky, K. B. Wisinski, R. O’Regan, et al (2021). Serial singlecell genomics reveals convergent subclonal evolution of resistance as patients with early-stage breast cancer progress on endocrine plus CDK4/6 therapy. Nature Cancer. Published, 06/2021.
• A. Beams & R. Bateman, and F. Adler (2021). Will SARS-CoV-2 Become Just Another Seasonal Coronavirus?. Viruses. Published, 05/2021.
• F. R. Adler & Maron, C (2021). Patterns of blubber fat deposition and evaluation of body condition in growing southern right whale calves (Eubalaena australis). Marine Mammal Science. Published, 05/2021.
• E. A. Fedak & F. R. Adler, L. M. Abegglen, and J. D. Schiffman (2021). ATM and ATR activation through crosstalk between DNA damage response pathways. Bull. Math. Biol. Vol. 83, 1-30. Published, 03/2021.
• R. Beckman & I. Kareva, J. Pepper, and F. R. Adler (2020). How should cancer models be constructed? . Cancer Control. Published, 09/2020.
  https://doi.org/10.1177/1073274820962008
• T. T. Le & F. R. Adler (2020). Is mammography screening beneficial: an individual-based stochastic model for breast cancer incidence and mortality. British Journal of Cancer. Published, 07/2020.
  https://doi.org/10.1371/journal.pcbi.1008036
• Proc. Nat. Acad. Sci., 117:16072-16082. Published, 07/2020.
• T. G. Liou & C. Kartsonaki, R. H. Keogh, and F. R. Adler (2020). Evaluation of a five-year predicted survival model for cystic fibrosis in later time periods. Scientific Reports. Published, 04/2020.
  https://doi.org/10.1038/s41598-020-63590-8
• F. R. Adler & A. Green, and C. H. Sekercioglu (2020). Citizen science in ecology: A place for humans in nature. Annals of the New York Academy of Sciences. Published, 03/2020.
  https://doi.org/10.1111/nyas.14340
• F. R. Adler (2019). Cancer ecology and evolution: Positive interactions and system vulnerability. Current Opinion in Systems Biology. Vol. 17, 1-7. Published, 10/01/2019.
  https://doi.org/10.1016/j.coisb.2019.09.001
• Theodore Liou & Frederick R Adler, Natalia Argel, Fadi As- four, Perry S Brown, Barbara A Chatfield, Cori L Daines, Dixie Durham, Jessica A Francis, Barbara Glover, et al. (2019). Prospective multicenter randomized patient recruitment and sample collection to enable future measurements of sputum biomarkers of in ammation in an observa- tional study of cystic brosis. BMC medical research methodology. Vol. 19. Published, 04/26/2019.
• F. R. Adler & C. Stockmann, K. Ampofo, A. T. Pavia, and C. L. Byington (2018). Transmission of rhinovirus in the Utah BIG-LoVE families: Con- sequences of age and household structure. PLoS One. Published, 07/2018.
  https://journals.plos.org/plosone/article?id=10.13...
• A. M. Granchelli (2018). Microbial interactions in the cystic fibrosis airway. Journal of Clinical Microbiology. Published, 05/2018.
  https://jcm.asm.org/content/56/8/e00354-18
• J. J. Horns (2018). Using opportunistic citizen science data to estimate avian population trends. Biological Conservation. Vol. 221, 151-159. Published, 05/2018.
  https://doi.org/10.1016/j.biocon.2018.02.027
• F. R. Adler & S. Quinonez, N. Plowes, and E. S. Adams (2018). A mechanistic model of ant battles and its consequences for territory scaling. American Naturalist. Vol. 192, 204-216. Published, 03/2018.
  https://www.amnat.org/an/newpapers/AugAdler.html
• R. S. Sorenson & M. J. Deshotel, K. Johnson, F. R. Adler, and L. E. Sieburth (2018). Arabidopsis mRNA decay landscape arises from specialized RNA decay substrates, decapping-mediated feedback, and redundancy . Proceedings of the National Academy of Sciences. 201712312. Published, 02/2018.
  https://www.pnas.org/content/115/7/E1485
• L. Zinn-Bjorkman (2018). Modeling factors that regulate cell cooperativity in the zebrafish posterior lateral line primordium. J. Theor. Biol. Vol. 65, 1282-1288. Published, 02/2018.
  https://www.ncbi.nlm.nih.gov/pubmed/29470991
• K. A. Brown & N. Daneman, M. Jones, K. Nechodom, V. Stevens, F. R. Adler, M. B. Goetz, J. Mayer, and M. Samore (2017). The drivers of acute and long-term care Clostridium dicile infection rates: A retrospective multilevel cohort study of 251 facilities. Clinical Infectious Diseases. Vol. 65, 1282-1288. Published, 10/01/2017.
• J. Lee & J. Lee, F. R. Adler, and P. S. Kim (2017). A mathematical model for the macrophage response to respiratory viral infection in normal and asthmatic conditions. Bull. Math. Biol. Published, 09/01/2017.
• J. L. Jensen & J. L. Jensen, C. R. Jones, C. Kartsonaki, K. A. Packer, F. R. Adler, and T. G. Liou, (2017). Sleep phase delay in cystic fibrosis: A potential new manifestation of cystic fibrosis transmembrane regulator dysfunction. Chest. Vol. 152. Published, 08/01/2017.
• A. K. Miller & A. K. Miller, K. Munger, and F. R. Adler (2017). A Mathematical Model of Cell Cycle Dysregulation Due to Human Papillomavirus Infection. Bull. Math. Biol. Published, 07/01/2017.
• A. T. Tredennick & A. T. Tredennick, P. B. Adler, and F. R. Adler (2017). The relationship between species richness and ecosystem variability is shaped by the mechanism of coexistence. Ecol. Lett. Vol. 20. Published, 06/09/2017.
• N. Lewis-Rogers & N. Lewis-Rogers, J. Seger, and F. R. Adler (2017). Human rhinovirus diversity and evolution: How strange the change from major to minor. J. Virol. Vol. 91. Published, 01/12/2017.
• Convergence in leaf size versus twig leaf area scaling: do plants optimize leaf area partitioning? Annals of Botany, 2016. Published, 09/15/2016.
• Harnessing intra-host strain competition to limit antibiotic resistance: Mathematical model results, Bull. Math. Biol., 78:1828-1846, 2016. Published, 09/01/2016.
• Importation, Antibiotics, and Clostridium dicile Infection in Veteran Long-Term Care: A Multilevel Case-Control Study, Annals of Internal Medicine, 2016. Published, 06/01/2016.
• The dynamics of disease progression in cystic fibrosis, PLoS ONE 11:e0156752, 2016. Published, 06/01/2016.
• A mathematical model of T1D acceleration and delay by viral infection. Published, 03/01/2016.
• K. A. Brown, M. Jones, F. R. Adler, M. Leecaster, K. Nechodom, V. Stevens, M. Samore, and J. Mayer, The determinants of C. dicile infection in long- term care facilities: a portrait of patient-and facility-level factors across 90 care regions in the veterans affairs health care system, Antimicrobial Resistance and Infection Control, 4:O36, 2015. Published, 12/01/2015.
• S. Bhattacharyya and P. H. Gesteland and K. Korgenski and O. N. Bjornstad and Adler, F. R., Cross-immunity between strains explains the dynamical pat- tern of paramyxoviruses, Proc. Nat. Acad. Sci. 112:13396-13400, 2015. Published, 11/27/2015.
• C. L. Byington, K. Ampofo, C. Stockmann, F. R. Adler, A. Herbener, T. Miller, X. Sheng, A. J. Blaschke, R. Crisp, and A. T. Pavia, Community surveillance of respiratory viruses among families in the Utah Better Identi- cation of Germs-Longitudinal Viral Epidemiology (BIG-LoVE) study, Clinical Infectious Diseases, 61: 1217-1224, 2015. Published, 09/24/2015.
• D. J. A. Toth, A. V. Gundlapalli, K. Khader, , W. B. P. Pettey, M. A. Rubin, F. R. Adler, and M. H. Samore, , Emerging Infect. Dis., 21:14021408, 2015. Published, 08/01/2015.
• J. Kubinak, D. Cornwall, F. R. Adler, and W. K. Potts, Serial infection of diverse host (Mus) genotypes rapidly impedes pathogen tness and virulence, Proc. Roy. Soc. B, 282, 2015. Published, 06/22/2015.
• R. Boschert, F. R. Adler, and D. F. Blair, Loose coupling in the bacterial agellar motor, Proc. Nat. Acad. Sci. 112: 4755-4760, 2015. Published, 04/14/2015.
• S. M. Countryman, M. C. Stumpe, S. P. Crow, F. R. Adler, M. J. Greene, M. Vonshak and D. M. Gordon, Collective search by ants in microgravity, Frontiers in Ecology and Evolution 3:A25, 2015. Published, 01/30/2015.
• C. J. Tanner, F. R. Adler, N. B. Grimm, P. M. Groman, S. A. Levin, J. Munshi-South, D. E. Pataki, M. Pavao-Zuckerman, and W. G. Wilson, Urban ecology: advancing science and society, Frontiers in Ecology and the Environment, 12:574-581, 2014. Published, 12/09/2014.
• E. J. Graham and F. R. Adler. Long-term models of oxidative stress and mitochondrial damage in insulin resistance progression. Journal of Theoretical Biology, 340:238-250, 2014. Published, 09/29/2014.
• C. H. Remien, F. R. Adler, L. A. Chesson, L. O. Valenzuela, J. R. Ehleringer, and T. E. Cerling. Deconvolution of isotope signals from bundles of multiple hairs. Oecologia, 175:781-789, 2014. Published, 07/01/2014.
• Remien, C.H., Sussman, N.L. and Adler, F.R. Mathematical modelling of chronic acetaminophen metabolism and liver injury Mathematical Medicine and Biology, 301:302-317, 2014. Published, 06/20/2014.
• S. Ghosh, J. L. Waite, D. H. Clayton, and F. R. Adler. Can antibodies against flies alter malaria transmission in birds by changing vector behavior? J. Theor. Biol., 358:93-101, 2014. Published, 05/29/2014.
• S. Bewick, K. L Stuble, J.-P. Lessard, R. R. Dunn, F. R. Adler, and N. J. Sanders. Predicting future coexistence in a North American ant community. Ecology and Evolution, 4:1804-1819, 2014. Published, 04/14/2014.
• Adler, Frederick R. (2012). Modeling the Dynamics of Life. Brooks/Cole Pub Co. Published, 01/01/2012.
• Effect of 1918 PB1-F2 expression on influenza A virus infection kinetics. PLoS Computational Biology, 7:e1001081, 2011. Published, 05/2011.
• The effects of intraspecific density dependence on species richness and species abundance distributions. Published, 04/2011.

Research Keywords

• Virology
• Urban Ecology
• Mathematical Modeling
• Mathematical Ecology
• Immunology
• Evolutionary Ecology
• Computational Biology
• Behavioral Ecology

Presentations

• University of Texas Health Houston. Invited Talk/Keynote, Submitted, 06/2022.
• Department of Integrative Biology, UC Berkeley. Invited Talk/Keynote, Presented, 12/12/2019.
• Ostrom Lecture, Washington State University. Invited Talk/Keynote, Presented, 04/11/2019.
• Department of Mathematics, Utah State University. Invited Talk/Keynote, Presented, 04/04/2019.
• Department of Mathematics, Brigham Young University. Invited Talk/Keynote, Presented, 03/28/2019.
• National Socio-Environmental Synthesis Center (SESYNC) University of Idaho, IBEST. Invited Talk/Keynote, Presented, 07/07/2017.
• Britton Lectures, McMaster University, St. Jude Children's Hospital. Invited Talk/Keynote, Presented, 08/01/2016.