Education
- B.S., Chemistry, University of North Carolina, Chapel Hill
- NIH NRSA Postdoctoral Fellow, Department of Chemistry, Mentor: Tom Muir, Princeton University
- PhD, Chemistry, Mentor: Eric Anslyn, University of Texas at Austin
Research Interests
Dr. Diehl is broadly interested in understanding the biochemical mechanisms of epigenetic regulation by post-translational modifications (PTMs) of chromatin and chromatin-associated proteins. In particular, her research seeks to elucidate links between gene expression and metabolism via these chromatin PTMs. To do so, her lab is developing and deploying chemical tools to study these PTMs in biochemical and cell-based assays. Importantly, dysregulation of these PTMs is known to play a role in a number of diseases including cancer and metabolic and developmental disorders. By understanding how chromatin PTMs are regulated and how they impact gene expression, Dr. Diehl’s work seeks to identify new therapeutic strategies for targeting epigenetic dysfunctions.