Tara Mastren portrait
  • Assistant Professor, Civil And Environmental Engin
801-581-7277

Publications

  • Kirkeby EK, Chyan MK & Diehl G (2022). Design and synthesis of astatinated benzothiazole compounds for their potential use in Targeted Alpha Therapy (TAT) strategies to treat Alzheimer's disease-associated amyloid plaques. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. Vol. 191, 110555110555. Published, 12/01/2022.
  • Tara Mastren (2021). Targeted Alpha Therapy, Rare Earth Elements and Actinides: Progress in Computational Science Applications. American Chemical Society. Published, 10/20/2021.
  • Hao G, Mastren T, Silvers W, Hassan G, Öz OK & Sun X (2021). Copper-67 radioimmunotheranostics for simultaneous immunotherapy and immuno-SPECT. Scientific reports. Vol. 11, 3622. Published, 02/11/2021.
  • Mastren T, Akin A, Copping R, Brugh M, Wilbur DS, Birnbaum ER, Nortier FM, John KD & Fassbender ME (2021). A reverse 230U/226Th radionuclide generator for targeted alpha therapy applications. Nuclear medicine and biology. Vol. 90-91, 69-73. Published, 01/01/2021.
  • Ferrier MG, Li Y, Chyan MK, Wong R, Li L, Spreckelmeyer S, Hamlin DK, Mastren T, Fassbender ME, Orvig C & Wilbur DS (2020). Thorium chelators for targeted alpha therapy: Rapid chelation of thorium-226. Journal of labelled compounds & radiopharmaceuticals. Vol. 63, 502-516. Published, 12/01/2020.
  • Friend MT, Mastren T, Parker TG & Vermeulen CE (2020). Production of 230Pa by proton irradiation of 232Th at the LANL isotope production facility: Precursor of 230U for targeted alpha therapy. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. Vol. 156, 108973. Published, 11/01/2020.
  • Friend MT, Parker TG, Mastren T, Mocko V, Brugh M, Birnbaum ER & Fassbender ME (2020). Extraction chromatography of 225Ac and lanthanides on N,N-dioctyldiglycolamic acid /1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide solvent impregnated resin. Journal of chromatography. A. Vol. 1624, 461219. Published, 08/01/2020.
  • Mathew K, Kayzar-Boggs T, Varga Z, Gaffney A, Denton J, Fulwyler J, Garduno K, Gaunt A, Inglis J, Keller R, Kinman W, Labotka D, Lujan E, Maassen J, Mastren T, May I, Mayer K, Nicholl A, Ottenfeld C, Parsons-Davis T, Porterfield D, Rim J, Rolison J, Stanley F, Steiner R, Tandon L, Thomas M, Torres R, Treinen K, Wallenius M, Wende A, Williams R & Wimpenny J (2019). Intercomparison of the Radio-Chronometric Ages of Plutonium-Certified Reference Materials with Distinct Isotopic Compositions. Analytical chemistry. Vol. 91, 11643-11652. Published, 09/01/2019.
  • E Paige Abel, Mikael Avilov, Virginia Ayres, Eva Birnbaum, Georg Bollen, Greg Bonito, Todd Bredeweg, Hannah Clause, Aaron Couture, Joe DeVore, Matt Dietrich, Paul Ellison, Jonathan Engle, Richard Ferrieri, Jonathan Fitzsimmons, Moshe Friedman, Dali Georgobiani, Stephen Graves, John Greene, Suzanne Lapi, C Shaun Loveless, Tara Mastren, Cecilia Martinez-Gomez, Sean McGuinness, Wolfgang Mittig, David Morrissey, Graham Peaslee, Frederique Pellemoine, J David Robertson, Nicholas Scielzo, Matthew Scott, Gregory Severin, Dawn Shaughnessy, Jennifer Shusterman, Jaideep Singh, Mark Stoyer, Logan Sutherlin, Ate Visser & John Wilkinson (2019). Isotope harvesting at FRIB: additional opportunities for scientific discovery. Journal of Physics G: Nuclear Particle Physics. 1-33. Published, 08/20/2019.
    https://iopscience.iop.org/article/10.1088/1361-64...
  • Mastren T, Stein BW, Parker TG, Radchenko V, Copping R & Owens A (2019). Separation of Protactinium Employing Sulfur-Based Extraction Chromatographic Resins. Analytical chemistry. Vol. 90, 7012-7017. Published, 04/01/2019.
  • Tara Mastren & Christiaan Vermeulen, Mark Brugh, Eva R. Birnbaum, Meiring F. Nortier, and Michael E. Fassbender (2019). Natural nickel as a proton beam energy monitor for energies ranging from 15 to 30 MeV. Nuclear Instruments and Methods in Physics Research B. Published, 01/29/2019.
  • Mastren T, Radchenko V, Engle JW, Weidner JW, Owens A & Wyant LE (2018). Chromatographic separation of the theranostic radionuclide 111Ag from a proton irradiated thorium matrix. Analytica chimica acta. Vol. 998, 75-82. Published, 08/01/2018.
  • Eva R Birnbaum, Michael E Fassbender, Maryline G Ferrier, Kevin D John & Tara Mastren (2018). Actinides in Medicine, The Heaviest Metals: Science and Technology of the Actinides and Beyond. John Wiley & Sons, Ltd. Published, 07/02/2018.
  • Hopkins PD, Mastren T, Florek J, Copping R & Brugh M (2018). Synthesis and radiometric evaluation of diglycolamide functionalized mesoporous silica for the chromatographic separation of actinides Th, Pa and U. Dalton transactions (Cambridge, England : 2003). Vol. 47, 5189-5195. Published, 04/01/2018.
  • Radchenko V, Engle JW, Medvedev DG, Maassen JM, Naranjo CM, Unc GA & Meyer CAL (2018). Proton-induced production and radiochemical isolation of 44Ti from scandium metal targets for 44Ti/44Sc generator development. Nuclear medicine and biology. Vol. 50, 25-32. Published, 01/01/2018.
  • Mastren T, Radchenko V, Bach HT, Balkin ER, Birnbaum ER, Brugh M, Engle JW, Gott MD, Guthrie J & Hennkens HM (2017). Bulk production and evaluation of high specific activity 186gRe for cancer therapy using enriched 186WO3 targets in a proton beam. Nuclear medicine and biology. Vol. 49, 24-29. Published, 12/01/2017.
  • Mastren T., Radchenko V., Hopkins P., Engle J., Weidner J., Copping R., Brugh M., Nortier F., Birnbaum E., John K. & Fassbender M. (2017). Separation of103Ru from a proton irradiated thorium matrix: A potential source of Auger therapy radionuclide103mRh. PLoS ONE. Vol. 12. Published, 12/01/2017.
  • Mastren T., Radchenko V., Owens A., Copping R., Boll R., Griswold J., Mirzadeh S., Wyant L., Brugh M., Engle J., Nortier F., Birnbaum E., John K. & Fassbender M. (2017). Simultaneous Separation of Actinium and Radium Isotopes from a Proton Irradiated Thorium Matrix. Scientific Reports. Vol. 7. Published, 12/01/2017.
  • Radchenko V., Mastren T., Meyer C., Ivanov A., Bryantsev V., Copping R., Denton D., Engle J., Griswold J., Murphy K., Wilson J., Owens A., Wyant L., Birnbaum E., Fitzsimmons J., Medvedev D., Cutler C., Mausner L., Nortier M., John K., Mirzadeh S. & Fassbender M. (2017). Radiometric evaluation of diglycolamide resins for the chromatographic separation of actinium from fission product lanthanides. Talanta. Vol. 175, 318-324. Published, 12/01/2017.
  • Kumar A, Mastren T & Wang B (2017). Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics. Bioconjugate chemistry. Vol. 27, 1681-9. Published, 06/01/2017.
  • Radchenko V, Meyer CAL, Engle JW, Naranjo CM & Unc GA (2017). Separation of 44Ti from proton irradiated scandium by using solid-phase extraction chromatography and design of 44Ti/44Sc generator system. Journal of chromatography. A. Vol. 1477, 39-46. Published, 04/01/2017.
  • Mastren T, Pen A, Loveless S, Marquez BV & Bollinger E (2016). Harvesting (67)Cu from the Collection of a Secondary Beam Cocktail at the National Superconducting Cyclotron Laboratory. Analytical chemistry. Vol. 87, 10323-9. Published, 04/01/2016.
  • Mastren T., Marquez B., Sultan D., Bollinger E., Eisenbeis P., Voller T. & Lapi S. (2015). Cyclotron production of high - Specific activity55Co and in vivo evaluation of the stability of55Co metal-chelate-peptide complexes. Molecular Imaging. Vol. 14, 526-532. Published, 11/01/2015.
  • Mastren T, Guthrie J & Eisenbeis P (2015). Specific activity measurement of ⁶⁴Cu: a comparison of methods. Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine. Vol. 90, 117-21. Published, 04/01/2015.
  • Mastren T., Pen A., Peaslee G., Wozniak N., Loveless S., Essenmacher S., Sobotka L., Morrissey D. & Lapi S. (2014). Feasibility of isotope harvesting at a projectile fragmentation facility:67Cu. Scientific Reports. Vol. 4. Published, 10/21/2014.
  • Pen A., Mastren T., Peaslee G., Petrasky K., Deyoung P., Morrissey D. & Lapi S. (2014). Design and construction of a water target system for harvesting radioisotopes at the National Superconducting Cyclotron Laboratory. Nuclear Instruments and Methods in Physics Research, Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. Vol. 747, 62-68. Published, 05/21/2014.
  • Aweda T., Ikotun O., Mastren T., Cannon C., Wright B., Youngs W., Cutler C., Guthrie J. & Lapi S. (2013). The use of 111Ag as a tool for studying biological distribution of silver-based antimicrobials. MedChemComm. Vol. 4, 1015-1017. Published, 06/01/2013.

Research Keywords

  • Targeted Radiotherapy
  • Radiochemistry
  • Radiochemical Separations
  • Nuclear Reactions
  • Nuclear Medicine
  • Nuclear Forensics
  • Lanthanide Chemistry
  • Isotope Production
  • Actinide Chemistry

Presentations

  • Production And Availability Of Therapeutic Radionuclides Made In Nuclear Reactors for the Society of Nuclear Medicine and Molecular Imaging Annual Meeting Chicago. Invited Talk/Keynote, Presented, 06/24/2023.
  • Panelist for Theranostic Workshop at the International Society of Radiopharmaceutical Sciences meeting in Honolulu Hawaii. I served as the expert on radionuclide production and purification. Other, Presented, 05/22/2023.
  • The Production and Application of Radionuclides for Targeted Radiotherapy. Presented to ARCS (advancing science in america) Utah chapter. Invited Talk/Keynote, Presented, 11/15/2022.
  • Production and separation of 230Pa for targeted alpha therapy applications utilizing progeny radionuclides 230U/226Th, International Workshop on Targetry and Target Chemistry, Coimbra, Portugal. Conference Paper, Refereed, Presented, 08/30/2018.
  • Chromatographic separation of Medically-Related Radionuclides from Proton-Irradiated Thorium Targets, 254th American Chemical Society National Meeting & Exposition, Washington D.C. Conference Paper, Refereed, Presented, 08/20/2017.
  • A generator concept to yield 226Th: an isotope of interest for targeted alpha therapy, 22nd International Symposium on Radiopharmaceutical Sciences, Dresden, Germany. Conference Paper, Refereed, Presented, 05/15/2017.
  • Selective Extraction of Medically-Related Radionuclides from Proton-Irradiated Thorium Targets, 16th International Workshop on Targetry and Target Chemistry, Santa Fe, NM. Conference Paper, Refereed, Presented, 08/29/2016.
  • Isotope Harvesting at Heavy Ion Fragmentation Facilities, 15th International Workshop on Targetry and Target Chemistry, Prague, Czech Republic. Conference Paper, Refereed, Presented, 08/20/2014.
  • Separation Chemistries for Isotope Harvesting at Heavy Ion Fragmentation Facilities, University Industry Technical Interchange, Walnut Creek, CA. Conference Paper, Refereed, Presented, 06/15/2014.
  • Transition Metal Ion Chromatography to Measure True Specific Activity of 64Cu, Radiometals, Sonoma, CA. Conference Paper, Refereed, Presented, 06/13/2013.
  • Studies for Isotope Harvesting at the Facility for Rare Isotope Beams, NSSC Webinar. Conference Paper, Refereed, Presented, 03/21/2013.

Research Groups

  • Lauren Hoekstra, Undergraduate Student. 06/05/2023 - 07/28/2023. Awards/Scholarships/Stipends: HIPPO Undergraduate performed summer research in my group. Fellowship from HIPPO.
  • Melanie Guerrero, Undergraduate Student. 06/05/2023 - 07/28/2023.
  • Sophia Birkner, Undergraduate Student. 05/10/2021 - 08/01/2022.
  • Colton Dixon, Undergraduate Student. 08/17/2020 - 05/07/2021.