SAVEEZ SAFFARIAN portrait
  • Faculty, Center for Cell and Genome Sciences
  • Associate Professor, Physics And Astronomy
  • Adjunct Associate Professor, School Of Biological Sciences

Publications

  • Manon Gourdelier, Jitendriya Swain, Coline Arone, Anita Mouttou, David Bracquemond , Peggy Merida, Saveez Saffarian , Sébastien Lyonnais, Cyril Favard & Delphine Muriaux (2022). Optimized production and fluorescent labeling of SARS-CoV-2 virus-like particles. Scientific Reports. Vol. 12. Published, 08/27/2022.
    https://www.nature.com/articles/s41598-022-18681-z
  • Ali Shargh, Aude Picard, Rostislav Hrubiak, Dongzhou Zhang , Russell J Hemley, Shanti Deemyad, Niaz Abdolrahim & Saveez Saffarian (2022). Coexistence of vitreous and crystalline phases of H2O at ambient temperature. Proc Natl Acad Sci U S A . Vol. 119. Published, 07/05/2022.
    https://www.pnas.org/doi/abs/10.1073/pnas.21172811...
  • Shargh AK, Picard A, Hrubiak R & Zhang D (2022). Coexistence of vitreous and crystalline phases of H2O at ambient temperature. Proceedings of the National Academy of Sciences of the United States of America. Vol. 119, e2117281119e2117281119. Published, 06/01/2022.
  • Ipsita Saha, Benjamin Preece, Abby Peterson, Haley Durden, Brian MacArthur, Jake Lowe, David Belnap, Michael Vershinin & Saveez Saffarian (2021). Gag-Gag Interactions Are Insufficient to Fully Stabilize and Order the Immature HIV Gag Lattice. Viruses. Vol. 13, 1946. Published, 09/28/2021.
    https://www.mdpi.com/1999-4915/13/10/1946
  • Saveez Saffarian (2021). Application of Advanced Light Microscopy to the Study of HIV and Its Interactions with the Host. Viruses. Published, 02/01/2021.
    https://www.mdpi.com/1999-4915/13/2/223
  • Heather Swann, Abhimanyu Sharma , Benjamin Preece, Abby Peterson, Crystal Eldridge, David M Belnap, Michael Vershinin & Saveez Saffarian (2020). Minimal system for assembly of SARS-CoV-2 virus like particles. Scientific Reports. Published, 12/14/2020.
    https://www.nature.com/articles/s41598-020-78656-w
  • Shilpa Gupta, Mourad Bendjennat & Saveez Saffarian (2020). Abrogating ALIX Interactions Results in Stuttering of the ESCRT Machinery. Viruses. Published, 09/16/2020.
    https://www.mdpi.com/1999-4915/12/9/1032
  • Shilpa Gupta, Josh Bromley & Saveez Saffarian (2020). High-speed imaging of ESCRT recruitment and dynamics during HIV virus like particle budding. PLoS One. Published, 09/04/2020.
    https://journals.plos.org/plosone/article?id=10.13...
  • Ipsita Saha & Saveez Saffarian (2020). Dynamics of the HIV Gag Lattice Detected by Localization Correlation Analysis and Time-Lapse iPALM. Biophysical Journal. Published, 08/04/2020.
    https://www.cell.com/biophysj/fulltext/S0006-3495(...
  • Ipsita Saha & Saveez Saffarian (2019). Interferometric fluorescence cross correlation spectroscopy. PLoS One. Published, 12/18/2019.
    https://journals.plos.org/plosone/article?id=10.13...

Research Statement

My lab focuses on enveloped RNA viruses including HIV, SARS-CoV-2 and VSV, mainly studying their assembly and replication. We also develop and use novel optical microscopy methods to visualize mechanism of viral replication in live cells. 

Grants, Contracts & Research Gifts

  • HIV R01. PI: SAFFARIAN,SAVEEZ. NIH NATIONAL INST OF GENERAL M, 06/03/2017 - 08/31/2022. Total project budget to date: $1,203,105.00