ROBERT A. CAMPBELL portrait
  • Adjunct Assistant Professor, Pathology
  • Research Assistant Professor, Internal Medicine
801-585-0727

Research Statement

My research efforts focus on dissecting the mechanisms underpinning how cells alter coagulation under normal and disease situations, as well as determining how hemostasis and thrombosis, in turns, alters cellular response during inflammation. In particular, I have focused on understanding the regulation of transcription and translation in megakaryocyte and platelets under health and disease conditions. To accomplish these goals, I have developed in vitro and in vivo model systems to examine gene and protein expression in megakaryocytes and platelets. We have also elucidated novel mechanisms regulating megakaryocyte and platelet function and activation under normal homeostasis, including translational control mechanism regulated by microRNAs. We have also discovered that platelets and megakaryocytes possess novel intrinsic host defense mechanisms in addition to their ability to respond to inflammatory signals that induce robust changes in gene and protein expression. We have also demonstrated these changes in gene expression alter thrombo-inflammatory responses, which often occur in the setting of aging and in the context of stroke. We also have extensively studied platelet interactions with other cells including neutrophils and monocytes and how these interactions alter platelet and leukocyte responses, including neutrophil extracellular trap formation (NET).

In addition, my laboratory has significant experience dissecting molecular pathway in platelets and neutrophils, which regulate thrombosis using murine model systems. This includes in vivo models of thrombosis such as venous thrombosis, pulmonary embolism, and ischemic stroke. In these studies, we have used state-of-the-art technologies including RNA-seq to examine the transcriptional changes in platelets and megakaryocytes from mice to uncover novel genes critical for platelet responses during inflammation and thrombosis.

Research Keywords

  • Thrombosis
  • Platelets
  • Inflammation
  • Infectious Disease
  • Stroke
  • Neutrophils

Presentations

  • The interface between coagulation, platelets, and inflammation in COVID-19. 10th Symposium of Hemostasis, Coagulation, Platelets, and Transfusion. Chapel Hill, North Carolina. April 30, 2022. , Presented, 2022.
  • Novel platelet interactions with the immune system. Case Western Reserve Graduate Student Seminar Department of Pharmacology. Cleveland, Ohio. , Presented, 2022.
  • Expression of Interferon Responsive Genes Regulate Functional Changes in Megakaryocytes and Platelets During Infection. National Heart Lung and Blood Institute COVID-19 Associated Coagulopathy. , Presented, 2021.
  • Understanding Why Infectious Diseases Cause Blood Clots. Vitae, University of Utah. , Presented, 2020.
  • Altered Immunohemostatic Responses in Dengue Fever and COVID-19. American Society of Hematology Scientific Workshop on Infectious Disease and Coagulation. , Presented, 2020.
  • Dysregulated Coagulation in Infectious Diseases. University of North Carolina at Chapel Hill Blood Research Center. , Presented, 2020.
  • Immunothrombosis During Clinical COVID-19 Disease. Platelet Physiology ISTH SSC Meeting. , Presented, 2020.
  • Novel Roles for Platelets in Infectious Disease and Thrombosis, Cardeza Foundation Thomas Jefferson University, Philadelphia, Pennsylvania, United States. , Presented, 2020.
  • Platelets in the War Against Viremia. American Society for Hematology Annual Meeting Atlanta Georgia. , Presented, 2021.
  • Dysregulated Platelet Function and Coagulation in COVID-19. Hemostasis and Thrombosis Research Society Annual Meeting. , Presented, 2021.
  • Campbell RA, Schwertz H, Tolley N, Diaz-Oritz R, Hunter-Mellado R, Bozza F, Washington V, Zimmerman GA, Weyrich AS. Type I Interferons Upregulate IFITM3 in Human Platelets and Megakaryocytes to Control Viral Infectivity 2019. Megakaryocytes and Platelet Gordon Research Conference. Galveston, Texas. Oral Presentation. , Presented, 2019.
  • The Effect of Zinc Metal on Antibiotic Resistances of Bacteria in a Tributary of the Enoree River in Upstate South Carolina, 64th Annual Meeting of the Association of Southeastern Biologists. , , 2003.
  • Stoller ML, Basak I, Alsobrooks J, Bray PF, Campbell RA. Cathepsin G Cleavage of PAR4 Generates a Novel Tethered Ligand That Induces Platelet Activation. Poster, Presented, 2020.
  • Krauel K, Campbell RA, Middleton E, Rondina MT, Bhatlekar S, Montenont E, Blair A, Weyrich AS. Lipopolysaccharide Induces IL6 and Upregulates IL8 Expression in Megakaryocytes. 2019. XXIX Congress of the International Society on Thrombosis and Haemostasis. Melbourne, Australia. Poster Presentation. Poster, Presented, 2019.
  • Campbell RA, Denorme F, Manne BK, Arajuo C, Majersik J, Weyrich AS, Rondina MT. The Mammalian Target of Rapamycin Controls Platelet Integrin Activation, Aggregation, and Ischemic Stroke. 2019. XXIX Congress of the International Society on Thrombosis and Haemostasis. Melbourne, Australia. Poster Presentation. Poster, Presented, 2019.
  • Bhatlekar S, Basak I, Campbell RA, Manne BK, Cody MJ, Nagalla S, Stroller M, Hugo S, Weyrich AS, Rondina MT, Edelstein LC, Bray PF. miR-125a-5p Regulates Human and Mouse Thrombopoiesis through Leukocyte Cytosolic Protein 1 (LCP1). 2019. Congress of the International Society on Thrombosis and Haemostasis. Melbourne, Australia. Poster Presentation. Poster, Presented, 2019.
  • Campbell RA, Denorme F, Manne BK, Majersik J, Weyrich AS, Rondina MT. Inflammation in Aging Increases Ischemic Stroke Burden. Poster session presented at International Stroke Conference, Honolulu. Poster, Presented, 2019.
  • Campbell RA, Manne BK, Saperstein S, Schwertz H, Rowley JW, Weyrich AS, Rondina MT. Interferon-induced Transmembrane 3 (IFITM3) on Megakaryocytes and Platelets Regulates Fibrinogen Endocytosis and Thrombosis During Inflammation in Aging. Poster session presented at Aging, Immunity, and Inflammation Keystone Symposia, Austin. Poster, Presented, 2018.
  • Basak I, Bhatlekar S, Campbell RA, Chahdi A, Kong X, Ma L, Rondina MT, Weyrich AS, Edelstein LC, Bray PF. Microrna-15a-5p Regulates Multiple Components of GPVI-Mediated Platelet and Megakaryocyte Activation Pathway. Poster session presented at 59th American Hematology Society Annual Meeting, Atlanta. Poster, Presented, 2017.
  • Guo, L Shen S, Rowley JW, McComas K, Su J, Manne BK, Berger B, Middleton E, Campbell RA, Weyrich AS, Rondina MT. Increased MHC Class I Expression on Platelets in Human and Murine Sepsis. Poster session presented at 59th American Hematology Society Annual Meeting, Atlanta. Poster, Presented, 2017.
  • Paul DS, Casari C, Wu C, Piatt R, Pasala K, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Weyrich AS, Bear JE, Bergmeier W. Arp2/3 is critical for platelet homeostasis but dispensable for hemostatic plug formation. Poster session presented at XXVIII Congress of the International Society on Thrombosis and Haemostasis, Berlin. Poster, Presented, 2017.
  • Manne BK, Campbell RA, Badolia R, Kunapuli SP, Weyrich AS, Rondina MT. Inhibition of MAP Kinase-interacting Kinase-1 (Mnk1) Regulates Platelet Functional Responses and Protein Synthesis in Megakaryocytes. Poster session presented at XXVIII Congress of the International Society on Thrombosis and Haemostasis, Berlin. Poster, Presented, 2017.
  • Manne BK, Munzer P, Badolia R, Campbell RA, Middleton E, Weyrich AS, Kunapuli SP, Borst O, Rondina MT. Crosstalk between PI3K and MAPK pathways regulates platelet function via PDK1. Poster session presented at XXVIII Congress of the International Society on Thrombosis and Haemostasis, Berlin. Poster, Presented, 2017.
  • Campbell RA, Shi D, Winters J, Bhatlekar S, Manne B, Jiang A, Saperstein S, Rondina MT, Bray PF, Weyrich AS. Calcium/calmodulin-dependent Protein Kinase II (CamKII) Regulates Platelet Formation. Poster session presented at XXVIII Congress of the International Society on Thrombosis and Haemostasis, Berlin. Poster, Presented, 2017.
  • Davizon-Castillo P, Ashworth K, Higa K, Hernandez G, Acharya S, Campbell RA, Rondina MT, Collins CB, Donato A, Lesniewski L, DeGregori J, Holer M, Banda N, Di Paola J, Pietras E. Pro-Inflammatory Cytokines Drive the Development of a Prothrombotic Platelet Phenotype in Inflammation and Aging. Poster session presented at 58th Annual American Society for Hematology Meeting, San Diego. Poster, Presented, 2016.
  • Middleton EA, Campbell RA, Harris ES, Major HD, Tolley ND, Weyrich AS, Zimmerman GA. Sepsis causes increased differential protein synthesis in platelets. Poster session presented at American Thoracic Society, San Francisco. Poster, Presented, 2016.
  • Nance D, Campbell RA, Rowley JW, Downie JM, Kahr WH, Mereby SA, Tolley ND, Zimmerman GA, Weyrich AS, Jorde LB, Rondina MT. Combined Variants in Factor VIII and PTGS-1 Amplify Hemorrhage Severity Across Three Generations of Descendants. Poster session presented at Thrombosis and Hemostasis Summit, Chicago. Poster, Presented, 2016.
  • Fidler TP, Campbell RA, Funari T, Dunne NG, Weyrich AS, Abel ED. Glucose Metabolism is Essential for Platelet Function. Poster session presented at American Heart Association Meeting, Orlando. Poster, Presented, 2015.
  • Casari C, Paul DS, Stefanini L, Boulaftali Y,
Campbell RA, Kechele DO, Caron KM, Weyrich AS,
Cowley DO, Parrott MC, Peters L, Bergmeier W. The RAP1-GAP RASA3 prevents clearance of circulating platelets. Poster session presented at 57th Annual American Society for Hematology Meeting, Orlando. Poster, Presented, 2015.
  • Machlus K, Wu SK, Stumpo DJ, Campbell RA, Weyrich AS, Blackshear PJ and Italiano JE. Synthesis of marcks in the late stages of megakaryocyte maturation drives proplatelet formation. Poster session presented at 57th Annual American Society for Hematology Meeting, Orlando. Poster, Presented, 2015.
  • Fidler TP, Middleton E, Rowley JW, Boudreau L, Campbell RA, Souvenir R, Funari T, Boilard E, Weyrich AS, Abel ED. Glucose transporter 3 is required for intragranular glycolysis and platelet activation. Poster session presented at 57th Annual American Society for Hematology Meeting, Orlando. Poster, Presented, 2015.
  • Campbell RA, Rowley JW, Weyrich AS, Rondina MT. Surface IFITMs on Megakaryocytes and Platelets Regulate Fibrinogen Endocytosis Under Inflammatory Conditions. Poster session presented at 57th Annual American Society for Hematology Meeting, Orlando. Poster, Presented, 2015.
  • Staddon JH, Smock KJ, Schiffman JD, Fluchel MN, Engel ME, Weyrich AS, Campbell RA. Pegasparaginase treatment alters thrombin generation by modulating the protein C and S system in acute lymphoblastic leukaemia/lymphoma. Poster session presented at 27th Annual Meeting of the American Society of Pediatric Hematology and Oncology, Chicago. Poster, Presented, 2014.
  • Machlus KR, Thon JN, Campbell RA, Weyrich AS, Italiano JE. Protein synthesis in the late stages of megakaryocyte maturation triggers proplatelet formation. Poster session presented at XXIV Congress of the International Society on Thrombosis and Haemostasis, Amsterdam. Poster, Presented, 2013.
  • Rondina MT, Campbell RA, Franks Z, Holloway, TH, Fraughton T, Zimmerman GA, Supiano MA, Weyrich AS. Platelet-Monocyte Interactions and Pro-Inflammatory Gene Synthesis is Increased in Healthy, Elderly Subjects. Poster session presented at American Geriatric Society, Galveston. Poster, Presented, 2013.
  • Marchi R, Walton BL, McGary CS, Lin FC, Ma AD, Pawlinski R, Mackman N, Campbell RA, DiPaola J, Wolberg AS. Dysregulated Coagulation from Coexisting Hypofibrinogenemia and Elevated Factor VIII. Poster session presented at Arteriosclerosis, Thrombosis, and Vascular Biology, Chicago. Poster, Presented, 2012.
  • Franks ZG, Campbell RA, Vieira de Abreu A, Zimmerman GA, Kraemer BF, Rondina MT.. Early Antibiotic Administration Reduces Methicillin-Resistant Staphylococcus Aureus Induced Cytokine Synthesis. Poster session presented at American Society of Clinical Investigation, Chicago. Poster, Presented, 2012.
  • Morris E, Campbell RA, Weyrich AS, Major HD. Severe Preeclampsia is Associated with Altered Thrombin Generation and Clot Structure. Poster session presented at Society for Maternal-Fetal Medicine, Dallas. Poster, Presented, 2012.
  • Campbell RA, Viera de Abreu A, Weyrich AS. Monocytes Embedded in Plasma Clots Synthesize Coagulation Factors: Balancing Procoagulant and Anticoagulant Signals. Poster session presented at Arteriosclerosis, Thrombosis, and Vascular Biology, Chicago. Poster, Presented, 2012.
  • Campbell RA, Smith TL, Vieira De Abreu A, Franks ZG, Kraiss L, Rondina MT, Zimmerman GA, Weyrich AS. Plasma Fibrin Clots Induce Inflammasome Mediated Cytokine Release. Poster session presented at Gordon Research Conference, Waterville Valley. Poster, Presented, 2012.
  • Campbell RA, Vieira de Abreu A, Weyrich AS. Monocytes Embedded in Plasma Clots Synthesize Coagulation Factors: Balancing Procoagulant and Anticoagulant Signals. Poster session presented at 4th Annual Symposium on Hemostasis with Special Focus on Factor VIIa and Tissue Factor, Chapel Hill. NC. Poster, Presented, 2012.
  • Vieira de Abreu A, Campbell RA, Weyrich AS, Castro-Faria-Neto HC, Zimmerman GA. The immunomodulatory activity of malaria pigment (hemozoin) on the innate immune response: platelets and monocytes as key effector cells. Poster session presented at The American Society of Tropical Medicine and Hygiene, Philadelphia. Poster, Presented, 2011.
  • Campbell RA, Smith TL, Franks ZG, Weyrich AS. Plasma Clots Induce Monocyte Inflammatory Cytokine Production: New Links Between Thrombosis and Inflammation. Poster session presented at XXIII Congress of the International Society on Thrombosis and Haemostasis, Kyoto. Poster, Presented, 2011.
  • Franks ZG, Campbell RA, Zimmerman GA, Weyrich AS, Rondina MT. Staphylococcus aureus Accelerates Thrombin Generation Through Increased Tissue Factor and Microparticles in Whole Blood. Poster session presented at XXIII Congress of the International Society on Thrombosis and Haemostasis., Kyoto. Poster, Presented, 2011.
  • Campbell RA, Weyrich AS, Supiano MA, Zimmerman GZ, Rondina MT. Platelet-Monocyte Aggregate Formation in Healthy Elderly Individuals Results in Increased Pro-Inflammatory Cytokine Secretion Compared to Healthy Young Subjects. Poster session presented at American Geriatric Society, Washington DC. Poster, Presented, 2011.
  • Smith TL, Franks ZG, Weyrich AS, Campbell RA. Plasma Fibrin Clots Induce Monocyte Inflammatory Cytokine Production: New Links Between Thrombosis and Inflammation. Poster session presented at Gordon Research Conference, Waterville Valley. Poster, Presented, 2010.
  • Campbell RA, Overmyer KA, Bagnell CR, Wolberg AS. Cellular Procoagulant Activities Dictate Clot Structure as a Function of Distance from the Cell Surface. Poster session presented at Arteriosclerosis, Thrombosis, and Vascular Biology, Atlanta. Poster, Presented, 2008.
  • Campbell RA, Overmyer KA, Larson B, Madden VJ, Bagnell CR, Wolberg AS. The Role of Cellular Procoagulant Activity in Clot Formation. Poster session presented at 9th Annual Women's Health Research Conference, Chapel Hill. Poster, Presented, 2008.
  • Campbell RA, Overmyer KA, Bagnell CR, Wolberg AS. Cell-Mediated In Situ Thrombin Generation Dictates Clot Structure as a Function of Distance from the Cell Surface. Poster session presented at 4th Annual Symposium on Hemostasis with Special Focus on Factor VIIa and Tissue Factor, Chapel Hill. Poster, Presented, 2008.
  • Gray L, Larson B, Englert JM, Campbell RA, Ezban M, Wolberg AS. Recombinant Factor VIIa Analog (V158D/E296V/M298Q-FVIIa, NN1731) Enhances Fibrin Formation, Structure and Stability in Hemophilic Plasma. Poster session presented at 8th Workshop on Novel Technologies and Gene Transfer for Hemophilia, Philadelphia. Poster, Presented, 2008.
  • Campbell RA, Overmyer KA, Bagnell CR, Wolberg AS. Differing Procoagulant Activities of Different Cell Types and Their Role in Fibrin Clot Formation. Poster session presented at Annual Pathology Research Symposium, Chapel Hill, NC. Poster, Presented, 2007.
  • Overmyer KA, Campbell RA, Wolberg AS. Role of Thrombin Activatable Fibrinolysis Inhibitor in Blood Clot Stability. Poster session presented at Research in the Capital, Chapel Hill. Poster, Presented, 2007.
  • Campbell RA, Wolberg AS. Cellular Procoagulant Activity Dictates Clot Structure as a Function of Distance from the Cell Surface. Poster session presented at Vascular Biology Forum, Chapel Hill. Poster, Presented, 2007.
  • Campbell RA, Fischer TH, Wolberg AS. Thrombin Generation on Rehydrated, Lyophilized Platelets in the Presence of Recombinant Factor VIIa. Poster session presented at Vascular Biology Forum, Chapel Hill. Poster, Presented, 2006.
  • Campbell RA, Fischer TH, Wolberg AS. Reconstituted, Lyophilized Platelets Support Thrombin Generation in the Presence of Recombinant Factor VIIa. Poster session presented at Vascular Biology Forum, Chapel Hill. Poster, Presented, 2005.
  • Cook E, Campbell RA, Liao MK. Characterizing Antibiotic Resistant Serratia marcesens in Watersheds of South Carolina (Honorable Mention). Poster session presented at 65th Annual Meeting of the Association of Southeastern Biologists. Poster, Presented, 2004.

Languages

  • English, Fluent.

Publications

  • Marchi R, Walton BL, McGary CS, Lin FC, Ma AD, Pawlinski R, Mackman N, Campbell RA, Di Paola J, Wolberg AS (date unknown). Dysregulated coagulation associated with hypofibrinogenaemia and plasma hypercoagulability: implications for identifying coagulopathic mechanisms in humans. (pp. 516-26). Vol. 108. Accepted, .
  • Campbell RA, Stoller ML, Denorme F, Manne BK, Bhatlekar S, Tugolukova EA, Bray PF. (date unknown). Blockade of Human PAR4 in Novel Humanized Mouse Strains Supports PAR4 As a Potential Target in Stroke: Ex Vivo Demonstration of Platelet Hyperreactivity of the Thr120 Variant. Accepted, .
  • Campbell RA, Schwertz H, Tolley N, Diaz-Oritz R, Hunter-Mellado R, Bozza F, Washington V, Zimmerman GA, Weyrich AS (date unknown). Type I Interferons Upregulate IFITM3 in Human Platelets and Megakaryocytes to Control Viral Infectivity. Accepted, .
  • Davizon-Castillo P, Aguila, S, Higa K, Ashworth K, Hernandez G, Bark D, Campbell RA, Rondina MT, DeGregori J, Pietras E, Di Paola J (date unknown). TNF-α is an Important Factor for Platelet Hyperreactivity in Aging. Accepted, .
  • Campbell RA, Manne BK, Saperstein S, Schwertz H, Rowley JW, Weyrich AS, Rondina MT (date unknown). Interferon-induced Transmembrane 3 (IFITM3) on Megakaryocytes and Platelets Regulates Fibrinogen Endocytosis and Thrombosis During Inflammation. Accepted, .
  • Campbell RA, Manne BK, Saperstein S, Schwertz H, Rowley JW, Weyrich AS, and Rondina MT (date unknown). Interferon-induced Transmembrane 3 (IFITM3) on Megakaryocytes and Platelets Regulates Fibrinogen Endocytosis and Thrombosis During Inflammation. Accepted, .
  • Tugolukova EM, Campbell RA, Hoerger KB, Schwertz H, Weyrich AS, Rowley JW (date unknown). Mitochondrial Fission Protein Drp1 Regulates Megakaryocyte and Platelet Mitochondrial Morphology, Platelet Numbers, and Platelet Function. Accepted, .
  • Manne BK, Badolia R, Campbell RA, Kunapuli SP, Weyrich AS, Rondina MT. (date unknown). Inhibition of MAP Kinase-Interacting Kinase-1 (Mnk1) Regulates Platelet Functional and Protein Synthesis in Megakaryocytes. Accepted, .
  • Campbell RA, Arajuo C, Manne BK, Rowley JW, Tolley N, Rondina MT, Weyrich AS. (date unknown). The Mammalian Target of Rapamycin in Megakaryocytes and Platelets Regulates Mortality and Disease Severity in Sepsis. Accepted, .
  • Guo L, Shen S, Rowley J, Jia W, Manne BK, Tolley N, McComas K, Su J, Jacob S, Campbell RA, Middleton E, Rondina MT, Weyrich AS. (date unknown). Platelets Suppress Antigen Specific CD8+ T Cells in Sepsis Through MHC Class I. Accepted, .
  • Middleton E, Rowley J, Campbell RA, Grissom C, Beesely S, Brown S, Schwertz H, Kosaka Y, Krauel K, Manne BK, Tolley N, Eustes A, Guo L, Paine R, Harris E, Zimmerman G. Weyrich AS, Rondina MT. (date unknown). Platelet Transcription and Translation Is Altered in Sepsis and Associated with Mortality. Accepted, .
  • Campbell RA, Cody M, Kosaka Y, Campbell HD, Yost CC (date unknown). Placental HTRA1 Protease Cleaves Alpha-1-Antitrypsin and Generates Neonatal NET-Inhibitory Factor. Accepted, .
  • Campbell RA, Smith TL, Vieira-de-Abreu A, Franks Z, Rowley JW, Majersik JJ, Rondina MT, Kraiss LW, Zimmerman GA, Weyrich AS (date unknown). Timely Fibrinolysis Blunts Cytokines Synthesized by Monocytes Embedded within Clots. Accepted, .
  • Fidler TP, Middleton E, Rowley JW, Boudreau L, Campbell RA, Souvenir R, Funari T, Boilard E, Weyrich AS, Abel ED (date unknown). Platelet specific knockout of glucose transporter 3 leads to altered metabolism and decreased platelet activation. Accepted, .
  • Campbell RA, Overmyer KA, Wolberg AS (date unknown). The Procoagulant Phenotype of the Cell Determines Fibrin Clot Structure. Accepted, .
  • Davizon-Castillo P, McMahon B, Aguila S, Jones KL, Trahan GD, Ashworth KJ, Bark D, Campbell RA, Higa K, Shih LC, Saunders N, DeGregori J, Rondina MT, DiPaola J (date unknown). TNF-α Driven Inflammation and Mitochondrial Dysfunction Characterize the Platelet Hyperreactivity of Aging and Myeloproliferative Neoplasms (MPN). Accepted, .
  • Campbell RA, Bhatnagar A, Franks Z, Rowley JW, Manne BK, Supiano MA, Weyrich AS, Rondina MT (date unknown). Granzyme A in Human Platelets Regulates Pro-Inflammatory Gene Synthesis in Aging. Accepted, .
  • Rowley JW, Campbell RA, Schwertz H, Weyrich AS, Tolly ND, Voora D, Rondina MT (date unknown). Transcript Expression, Intron Retention, and RNA Editing Are Conserved in Human Platelets over a 4 Year Period. Accepted, .
  • Carter JC, Campbell RA, Gibbons JA, Wolberg AS, Church FC (date unknown). Enhanced Cell-Associated Fibrinolytic Pathway but Not Coagulation Pathway Activity Contributes to Motility in Metastatic Breast Cancer Cells. Accepted, .
  • Campbell RA, Cody M, Yost CC (date unknown). Placental HTRA1 protease cleaves alpha-1-antitrypsin and generates neonatal NET-Inhibitory Factor. Accepted, .
  • Campbell RA, Smith TL, Tolley NS, Weyrich AS (date unknown). Platelets Synthesize Functional Urokinase Plasminogen Activator Receptor. Accepted, .
  • Campbell RA, Overmyer KA, Wolberg AS (date unknown). The Procoagulant Phenotype of the Cell Dictates Fibrin Clot Structure. Accepted, .
  • Campbell RA, Fischer TH, Wolberg AS (date unknown). A Novel Use of Rehydrated, Lyophilized Platelets Increases Recombinant Factor VIIa Procoagulant Activity in a Model of Hemophilia.Abstract #882, Poster presentation. Vol. 108. Accepted, .
  • Campbell RA, Fischer TH, Wolberg AS (date unknown). Activity of Recombinant Factor FVIIa (rFVIIa) on Reconstituted, Lyophilized Platelets in an in-vitro Model of Hemophilia. Accepted, .
  • Campbell RA, Fischer TH, Wolberg AS (date unknown). Reconstituted, Lyophilized Platelets Generate Thrombin in the Presence of Recombinant Factor VIIa. Abstract #4057, Poster Presentation. Vol. 106. Accepted, .
  • Davizon-Castillo P, Jones KL, Aguila S, Bark D, Ashworth KJ, Higa K, Pietras EM, Campbell RA, Shi LC, Saunders N, DeGregori J, Rondina MT, DiPaola J (date unknown). Aging-Associated Inflammation Due to Elevated Levels of TNF-α Increases Activation of the Integrin αIIbβ3 and the Procoagulant Potential of Platelets. Accepted, .
  • Campbell RA, Denorme F, Manne BK, Arajuo C, Majersik J, Weyrich AS, Rondina MT (date unknown). The Mammalian Target of Rapamycin Regulates Platelet Integrin Activation, Aggregation, and Ischemic Stroke. Accepted, .
  • Campbell HD, Manne BK, Tolley N, Yost CC, Campbell RA (date unknown). Platelet IFITM3 contributes to thrombosis in preeclampsia. Accepted, .
  • Campbell RA, Schwertz H, Tolley N, Diaz-Oritz R, Hunter-Mellado R, Bozza F, Washington V, Zimmerman GA, Weyrich AS (date unknown). Type I Interferons Upregulate IFITM3 in Human Platelets and Megakaryocytes to Control Viral Infectivity. Accepted, .
  • Fidler TP, Middleton E, Rowley JW, Boudreau L, Campbell RA, Souvenir R, Funari T, Boilard E, Weyrich AS, Abel ED (date unknown). Platelet specific knockout of glucose transporter 3 alters metabolism, reduces platelet activation in vitro and in vivo. Accepted, .
  • Franks ZG, Campbell RA, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Methicillin-resistant Staphylococcus aureus induces in vitro platelet activation and a procoagulant response. Accepted, .
  • Campbell RA, Machlus KR, Wolberg AS (date unknown). Smoking out the cause of thrombosis. Vol. 30, 7-8. Accepted, .
  • Azevedo-Quintanilha IG, Vieira-de-Abreu A, Ferreira AC, Reis PA, Silva TI, Nascimento DO, Campbell RA, Estato V, Weyrich AS, Bozza PT, Zimmerman GA, Castro-Faria-Neto HC (date unknown). Integrin αDβ2 influences cerebral edema, leukocyte accumulation and neurologic outcomes in experimental severe malaria. Vol. 14, e0224610. Accepted, .
  • Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell RA, Rowley JW, Salem D, Zufferey A, Laroche A, Lévesque T, Patey N, Rauch J, Lood C, Droit A, McKenzie SE, Machlus KR, Rondina MT, Lacroix S, Fortin PR, Boilard E (date unknown). FcγRIIA expression accelerates nephritis and increases platelet activation in systemic lupus erythematosus. Vol. 136, 2933-2945. Accepted, .
  • Kraemer BF, Campbell RA, Schwertz H, Franks ZG, Vieira de Abreu A, Grundler K, Kile BT, Dhakal BK, Rondina MT, Kahr WH, Mulvey MA, Blaylock RC, Zimmerman GA, Weyrich AS (date unknown). Bacteria differentially induce degradation of Bcl-xL, a survival protein, by human platelets. Vol. 120, 5014-20. Accepted, .
  • Rowley JW, Weyrich AS, Campbell RA (date unknown). TGFBIp: more than meets the eye?. Vol. 114, 5113-4. Accepted, .
  • Gray LD, Hussey MA, Larson BM, Machlus KR, Campbell RA, Koch G, Ezban M, Hedner U, Wolberg AS (date unknown). Recombinant factor VIIa analog NN1731 (V158D/E296V/M298Q-FVIIa) enhances fibrin formation, structure and stability in lipidated hemophilic plasma. Vol. 128, 570-6. Accepted, .
  • Campbell RA, Overmyer KA, Bagnell CR, Wolberg AS (date unknown). Cellular procoagulant activity dictates clot structure and stability as a function of distance from the cell surface. Vol. 28, 2247-54. Accepted, .
  • Jones CF, Campbell RA, Brooks AE, Assemi S, Tadjiki S, Thiagarajan G, Mulcock C, Weyrich AS, Brooks BD, Ghandehari H, Grainger DW (date unknown). Cationic PAMAM dendrimers aggressively initiate blood clot formation. Vol. 6, 9900-10. Accepted, .
  • Campbell RA, Overmyer KA, Selzman CH, Sheridan BC, Wolberg AS (date unknown). Contributions of extravascular and intravascular cells to fibrin network formation, structure, and stability. Vol. 114, 4886-96. Accepted, .
  • Trivedi S, Labuz D, Anderson CP, Araujo CV, Blair A, Middleton EA, Jensen O, Tran A, Mulvey MA, Campbell RA, Hale JS, Rondina MT, Leung DT (date unknown). Mucosal-associated invariant T (MAIT) cells mediate protective host responses in sepsis. Vol. 9. Accepted, .
  • Fidler TP, Campbell RA, Funari T, Dunne N, Balderas Angeles E, Middleton EA, Chaudhuri D, Weyrich AS, Abel ED (date unknown). Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function. Vol. 21, 1705. Accepted, .
  • Denorme F, Manne BK, Portier I, Petrey AC, Middleton EA, Kile BT, Rondina MT, Campbell RA (date unknown). COVID-19 patients exhibit reduced procoagulant platelet responses. Vol. 18, 3067-3073. Accepted, .
  • Nance D, Campbell RA, Rowley JW, Downie JM, Jorde LB, Kahr WH, Mereby SA, Tolley ND, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants. Vol. 14, 2230-2240. Accepted, .
  • Nance D, Campbell RA, Rowley JW, Downie JM, Jorde LB, Kahr WH, Mereby SA, Tolley ND, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Combined variants in factor VIII and prostaglandin synthase-1 amplify hemorrhage severity across three generations of descendants. Vol. 14, 2230-2240. Accepted, .
  • Kraemer BF, Campbell RA, Schwertz H, Cody MJ, Franks Z, Tolley ND, Kahr WH, Lindemann S, Seizer P, Yost CC, Zimmerman GA, Weyrich AS (date unknown). Novel anti-bacterial activities of beta-defensin 1 in human platelets: suppression of pathogen growth and signaling of neutrophil extracellular trap formation. Vol. 7, e1002355. Accepted, .
  • Bhatlekar S, Manne BK, Basak I, Edelstein LC, Tugolukova E, Stoller ML, Cody MJ, Morley SC, Nagalla S, Weyrich AS, Rowley JW, O'Connell RM, Rondina MT, Campbell RA, Bray PF (date unknown). miR-125a-5p regulates megakaryocyte proplatelet formation via the actin-bundling protein L-plastin. Vol. 136, 1760-1772. Accepted, .
  • Yost CC, Schwertz H, Cody MJ, Wallace JA, Campbell RA, Vieira-de-Abreu A, Araujo CV, Schubert S, Harris ES, Rowley JW, Rondina MT, Fulcher JM, Koening CL, Weyrich AS, Zimmerman GA (date unknown). Neonatal NET-inhibitory factor and related peptides inhibit neutrophil extracellular trap formation. Vol. 126, 3783-3798. Accepted, .
  • Bhatlekar S, Basak I, Edelstein LC, Campbell RA, Lindsey CR, Italiano JE Jr, Weyrich AS, Rowley JW, Rondina MT, Sola-Visner M, Bray PF (date unknown). Anti-apoptotic BCL2L2 increases megakaryocyte proplatelet formation in cultures of human cord blood. Vol. 104, 2075-2083. Accepted, .
  • Campbell RA, Vieira-de-Abreu A, Rowley JW, Franks ZG, Manne BK, Rondina MT, Kraiss LW, Majersik JJ, Zimmerman GA, Weyrich AS (date unknown). Clots Are Potent Triggers of Inflammatory Cell Gene Expression: Indications for Timely Fibrinolysis. Vol. 37, 1819-1827. Accepted, .
  • Staddon JH, Smock KJ, Schiffman JD, Fluchel MN, Engel ME, Weyrich AS, Campbell RA (date unknown). Pegasparaginase treatment alters thrombin generation by modulating the protein C and S system in acute lymphoblastic leukaemia/lymphoma. Vol. 26, 840-3. Accepted, .
  • Middleton EA, Rowley JW, Campbell RA, Grissom CK, Brown SM, Beesley SJ, Schwertz H, Kosaka Y, Manne BK, Krauel K, Tolley ND, Eustes AS, Guo L, Paine R 3rd, Harris ES, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Sepsis alters the transcriptional and translational landscape of human and murine platelets. Vol. 134, 911-923. Accepted, .
  • Manne BK, Denorme F, Middleton EA, Portier I, Rowley JW, Stubben C, Petrey AC, Tolley ND, Guo L, Cody M, Weyrich AS, Yost CC, Rondina MT, Campbell RA (date unknown). Platelet gene expression and function in patients with COVID-19. Vol. 136, 1317-1329. Accepted, .
  • Middleton EA, He XY, Denorme F, Campbell RA, Ng D, Salvatore SP, Mostyka M, Baxter-Stoltzfus A, Borczuk AC, Loda M, Cody MJ, Manne BK, Portier I, Harris ES, Petrey AC, Beswick EJ, Caulin AF, Iovino A, Abegglen LM, Weyrich AS, Rondina MT, Egeblad M, Schiffman JD, Yost CC (date unknown). Neutrophil extracellular traps contribute to immunothrombosis in COVID-19 acute respiratory distress syndrome. Vol. 136, 1169-1179. Accepted, .
  • Denorme F, Rustad JL, Campbell RA (date unknown). Brothers in arms: platelets and neutrophils in ischemic stroke. Vol. 28, 301-307. Accepted, .
  • Montenont E, Rondina MT, Campbell RA (date unknown). Altered functions of platelets during aging. Vol. 26, 336-342. Accepted, .
  • Machin DR, Bloom SI, Campbell RA, Phuong TTT, Gates PE, Lesniewski LA, Rondina MT, Donato AJ (date unknown). Advanced age results in a diminished endothelial glycocalyx. Vol. 315, H531-H539. Accepted, .
  • Fidler TP, Middleton EA, Rowley JW, Boudreau LH, Campbell RA, Souvenir R, Funari T, Tessandier N, Boilard E, Weyrich AS, Abel ED (date unknown). Glucose Transporter 3 Potentiates Degranulation and Is Required for Platelet Activation. Vol. 37, 1628-1639. Accepted, .
  • Shi DS, Smith MC, Campbell RA, Zimmerman PW, Franks ZB, Kraemer BF, Machlus KR, Ling J, Kamba P, Schwertz H, Rowley JW, Miles RR, Liu ZJ, Sola-Visner M, Italiano JE Jr, Christensen H, Kahr WH, Li DY, Weyrich AS (date unknown). Proteasome function is required for platelet production. Vol. 124, 3757-66. Accepted, .
  • Davizon-Castillo P, McMahon B, Aguila S, Bark D, Ashworth K, Allawzi A, Campbell RA, Montenont E, Nemkov T, D'Alessandro A, Clendenen N, Shih L, Sanders NA, Higa K, Cox A, Padilla-Romo Z, Hernandez G, Wartchow E, Trahan GD, Nozik-Grayck E, Jones K, Pietras EM, DeGregori J, Rondina MT, Di Paola J (date unknown). TNF-α-driven inflammation and mitochondrial dysfunction define the platelet hyperreactivity of aging. Vol. 134, 727-740. Accepted, .
  • Paul DS, Casari C, Wu C, Piatt R, Pasala S, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Machlus KR, Italiano JE Jr, Weyrich AS, Bear JE, Bergmeier W (date unknown). Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice. Vol. 1, 1398-1408. Accepted, .
  • Paul DS, Casari C, Wu C, Piatt R, Pasala S, Campbell RA, Poe KO, Ghalloussi D, Lee RH, Rotty JD, Cooley BC, Machlus KR, Italiano JE Jr, Weyrich AS, Bear JE, Bergmeier W (date unknown). Deletion of the Arp2/3 complex in megakaryocytes leads to microthrombocytopenia in mice. Vol. 1, 1398-1408. Accepted, .
  • Melki I, Allaeys I, Tessandier N, Mailhot B, Cloutier N, Campbell RA, Rowley JW, Salem D, Zufferey A, Laroche A, Lévesque T, Patey N, Rauch J, Lood C, Droit A, McKenzie SE, Machlus KR, Rondina MT, Lacroix S, Fortin P, Boilard E (date unknown). FcγRIIA expression aggravates nephritis and increases platelet activation in systemic lupus erythematosus in mice. Accepted, .
  • de Azevedo-Quintanilha IG, Vieira-de-Abreu A, Ferreira AC, Nascimento DO, Siqueira AM, Campbell RA, Teixeira Ferreira TP, Gutierrez TM, Ribeiro GM, E Silva PM, Carvalho AR, Bozza PT, Zimmerman GA, Castro-Faria-Neto HC (date unknown). Integrin αDβ2 (CD11d/CD18) mediates experimental malaria-associated acute respiratory distress syndrome (MA-ARDS). Vol. 15, 393. Accepted, .
  • Denorme F, Rustad JL, Portier I, Crandell JL, de Araujo CV, Cody MJ, Campbell RA, Yost CC (date unknown). Neutrophil extracellular trap inhibition improves survival in neonatal mouse infectious peritonitis. Accepted, .
  • Queisser KA, Mellema RA, Middleton EA, Portier I, Manne BK, Denorme F, Beswick EJ, Rondina MT, Campbell RA, Petrey AC (date unknown). COVID-19 generates hyaluronan fragments that directly induce endothelial barrier dysfunction. Accepted, .
  • Fidler TP, Campbell RA, Funari T, Dunne N, Balderas Angeles E, Middleton EA, Chaudhuri D, Weyrich AS, Abel ED (date unknown). Deletion of GLUT1 and GLUT3 Reveals Multiple Roles for Glucose Metabolism in Platelet and Megakaryocyte Function. Vol. 20, 881-894. Accepted, .
  • Portier I, Campbell RA, Denorme F (date unknown). Mechanisms of immunothrombosis in COVID-19. Accepted, .
  • de Azevedo-Quintanilha IG, Medeiros-de-Moraes IM, Ferreira AC, Reis PA, Vieira-de-Abreu A, Campbell RA, Weyrich AS, Bozza PT, Zimmerman GA, Castro-Faria-Neto HC (date unknown). Haem oxygenase protects against thrombocytopaenia and malaria-associated lung injury. Vol. 19, 234. Accepted, .
  • Campbell RA, Cody MJ, Manne BK, Zimmerman GA, Yost CC (date unknown). Interleukin 6 receptor alpha expression in PMNs isolated from prematurely born neonates: decreased expression is associated with differential mTOR signaling. Vol. 86, 55-62. Accepted, .
  • Schmid DI, Schwertz H, Jiang H, Campbell RA, Weyrich AS, McIntyre TM, Zimmerman GA, Kraiss LW (date unknown). Translational control of JunB, an AP-1 transcription factor, in activated human endothelial cells. Vol. 114, 1519-28. Accepted, .
  • Campbell RA, Fischer TH, Wolberg AS (date unknown). A novel approach to improving recombinant factor VIIa activity with a preserved platelet preparation. Vol. 138, 82-93. Accepted, .
  • Campbell RA, Campbell HD, Bircher JS, de Araujo CV, Denorme F, Crandell JL, Rustad JL, Monts J, Cody MJ, Kosaka Y, Yost CC (date unknown). Placental HTRA1 cleaves alpha-1-antitrypsin to generate a NET-Inhibitory Peptide. Accepted, .
  • Jones CF, Campbell RA, Franks Z, Gibson CC, Thiagarajan G, Vieira-de-Abreu A, Sukavaneshvar S, Mohammad SF, Li DY, Ghandehari H, Weyrich AS, Brooks BD, Grainger DW (date unknown). Cationic PAMAM dendrimers disrupt key platelet functions. Vol. 9, 1599-611. Accepted, .
  • Jones CF, Campbell RA, Franks Z, Gibson CC, Thiagarajan G, Vieira-de-Abreu A, Sukavaneshvar S, Mohammad SF, Li DY, Ghandehari H, Weyrich AS, Brooks BD, Grainger DW (date unknown). Cationic PAMAM dendrimers disrupt key platelet functions. Vol. 9, 1599-611. Accepted, .
  • Manne BK, Munzer P, Badolia R, Walker-Allgaier B, Campbell RA, Middleton E, Weyrich AS, Kunapuli SP, Borst O, Rondina MT (date unknown). PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway. Vol. 16, 1211-1225. Accepted, .
  • Manne BK, Münzer P, Badolia R, Walker-Allgaier B, Campbell RA, Middleton E, Weyrich AS, Kunapuli SP, Borst O, Rondina MT (date unknown). PDK1 governs thromboxane generation and thrombosis in platelets by regulating activation of Raf1 in the MAPK pathway. Vol. 16, 1211-1225. Accepted, .
  • Major HD, Campbell RA, Silver RM, Branch DW, Weyrich AS (date unknown). Synthesis of sFlt-1 by platelet-monocyte aggregates contributes to the pathogenesis of preeclampsia. Vol. 210, 547.e1-7. Accepted, .
  • Carter JC, Campbell RA, Gibbons JA, Gramling MW, Wolberg AS, Church FC (date unknown). Enhanced cell-associated plasminogen activator pathway but not coagulation pathway activity contributes to motility in metastatic breast cancer cells. Vol. 8, 1323-32. Accepted, .
  • Carter JC, Campbell RA, Gibbons JA, Gramling MW, Wolberg AS, Church FC (date unknown). Enhanced cell-associated plasminogen activator pathway but not coagulation pathway activity contributes to motility in metastatic breast cancer cells. Vol. 8, 1323-32. Accepted, .
  • Campbell RA, Hisada Y, Denorme F, Grover SP, Bouck EG, Middleton EA, Wolberg AS, Rondina MT, Mackman N (date unknown). Comparison of the coagulopathies associated with COVID-19 and sepsis. Vol. 5, e12525. Accepted, .
  • Campbell RA, Schwertz H, Hottz ED, Rowley JW, Manne BK, Washington AV, Hunter-Mellado R, Tolley ND, Christensen M, Eustes AS, Montenont E, Bhatlekar S, Ventrone CH, Kirkpatrick BD, Pierce KK, Whitehead SS, Diehl SA, Bray PF, Zimmerman GA, Kosaka Y, Bozza PT, Bozza FA, Weyrich AS, Rondina MT (date unknown). Human megakaryocytes possess intrinsic antiviral immunity through regulated induction of IFITM3. Vol. 133, 2013-2026. Accepted, .
  • Eustes AS, Campbell RA, Middleton EA, Tolley ND, Manne BK, Montenont E, Rowley JW, Krauel K, Blair A, Guo L, Kosaka Y, Medeiros-de-Moraes IM, Lacerda M, Hottz ED, Neto HCF, Zimmerman GA, Weyrich AS, Petrey A, Rondina MT (date unknown). Heparanase expression and activity are increased in platelets during clinical sepsis. Vol. 19, 1319-1330. Accepted, .
  • Sumanth MS, Jacob SP, Abhilasha KV, Manne BK, Basrur V, Lehoux S, Campbell RA, Yost CC, McIntyre TM, Cummings RD, Weyrich AS, Rondina MT, Marathe GK (date unknown). Different glycoforms of alpha-1-acid glycoprotein contribute to its functional alterations in platelets and neutrophils. Vol. 109, 915-930. Accepted, .
  • Fidler TP, Marti A, Gerth K, Middleton EA, Campbell RA, Rondina MT, Weyrich AS, Abel ED (date unknown). Glucose Metabolism Is Required for Platelet Hyperactivation in a Murine Model of Type 1 Diabetes. Vol. 68, 932-938. Accepted, .
  • Guo L, Shen S, Rowley JW, Tolley ND, Jia W, Manne BK, McComas KN, Bolingbroke B, Kosaka Y, Krauel K, Denorme F, Jacob SP, Eustes AS, Campbell RA, Middleton EA, He X, Brown SM, Morrell CN, Weyrich AS, Rondina MT (date unknown). Platelet MHC Class I Mediates CD8+ T Cell Suppression During Sepsis. Accepted, .
  • Rowley JW, Chappaz S, Corduan A, Chong MM, Campbell R, Khoury A, Manne BK, Wurtzel JG, Michael JV, Goldfinger LE, Mumaw MM, Nieman MT, Kile BT, Provost P, Weyrich AS (date unknown). Dicer1-mediated miRNA processing shapes the mRNA profile and function of murine platelets. Vol. 127, 1743-51. Accepted, .
  • Schwertz H, Rowley JW, Schumann GG, Thorack U, Campbell RA, Manne BK, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Endogenous LINE-1 (Long Interspersed Nuclear Element-1) Reverse Transcriptase Activity in Platelets Controls Translational Events Through RNA-DNA Hybrids. Vol. 38, 801-815. Accepted, .
  • Stefanini L, Paul DS, Robledo RF, Chan ER, Getz TM, Campbell RA, Kechele DO, Casari C, Piatt R, Caron KM, Mackman N, Weyrich AS, Parrott MC, Boulaftali Y, Adams MD, Peters LL, Bergmeier W (date unknown). RASA3 is a critical inhibitor of RAP1-dependent platelet activation. Vol. 125, 1419-32. Accepted, .
  • Franks Z, Campbell RA, Vieira de Abreu A, Holloway JT, Marvin JE, Kraemer BF, Zimmerman GA, Weyrich AS, Rondina MT (date unknown). Methicillin-resistant Staphylococcus aureus-induced thrombo-inflammatory response is reduced with timely antibiotic administration. Vol. 109, 684-95. Accepted, .
  • Rondina MT, Schwertz H, Harris ES, Kraemer BF, Campbell RA, Mackman N, Grissom CK, Weyrich AS, Zimmerman GA (date unknown). The septic milieu triggers expression of spliced tissue factor mRNA in human platelets. Vol. 9, 748-58. Accepted, .
  • Rondina MT, Schwertz H, Harris ES, Kraemer BF, Campbell RA, Mackman N, Grissom CK, Weyrich AS, Zimmerman GA (date unknown). The septic milieu triggers expression of spliced tissue factor mRNA in human platelets. Vol. 9, 748-58. Accepted, .
  • Machlus KR, Wu SK, Stumpo DJ, Soussou TS, Paul DS, Campbell RA, Kalwa H, Michel T, Bergmeier W, Weyrich AS, Blackshear PJ, Hartwig JH, Italiano JE Jr (date unknown). Synthesis and dephosphorylation of MARCKS in the late stages of megakaryocyte maturation drive proplatelet formation. Vol. 127, 1468-80. Accepted, .
  • Allen GA, Persson E, Campbell RA, Ezban M, Hedner U, Wolberg AS (date unknown). A variant of recombinant factor VIIa with enhanced procoagulant and antifibrinolytic activities in an in vitro model of hemophilia. Vol. 27, 683-9. Accepted, .
  • Rondina MT, Voora D, Simon LM, Schwertz H, Harper JF, Lee O, Bhatlekar SC, Li Q, Eustes AS, Montenont E, Campbell RA, Tolley ND, Kosaka Y, Weyrich AS, Bray PF, Rowley JW (date unknown). Longitudinal RNA-Seq Analysis of the Repeatability of Gene Expression and Splicing in Human Platelets Identifies a Platelet SELP Splice QTL. Vol. 126, 501-516. Accepted, .
  • Denorme F, Manne BK, Portier I, Eustes AS, Kosaka Y, Kile BT, Rondina MT, Campbell RA (date unknown). Platelet necrosis mediates ischemic stroke outcome in mice. Vol. 135, 429-440. Accepted, .
  • Denorme F, Portier I, Kosaka Y, Campbell RA (date unknown). Hyperglycemia exacerbates ischemic stroke outcome independent of platelet glucose uptake. Vol. 19, 536-546. Accepted, .
  • Griffiths TM, Page L, Weyrich AS, Rondina MT, Campbell RA (date unknown). Platelet electrical resistance for measuring platelet activation and adhesion in human health and disease. Vol. 198, 204-209. Accepted, .
  • Mor-Cohen R, Zucker M, Grissom C, Brown SM, Seligsohn U, Campbell RA, Blair AM, Rondina MT (date unknown). The reduced form of coagulation factor XI is associated with illness severity and coagulopathy in critically-ill septic patients. Vol. 47, 186-191. Accepted, .
  • Campbell RA, Boilard E, Rondina MT (date unknown). Is there a role for the ACE2 receptor in SARS-CoV-2 interactions with platelets?. Vol. 19, 46-50. Accepted, .
  • Portier I, Campbell RA (date unknown). Role of Platelets in Detection and Regulation of Infection. Vol. 41, 70-78. Accepted, .
  • Bouck EG, Denorme F, Holle LA, Middelton EA, Blair AM, de Laat B, Schiffman JD, Yost CC, Rondina MT, Wolberg AS, Campbell RA (date unknown). COVID-19 and Sepsis Are Associated With Different Abnormalities in Plasma Procoagulant and Fibrinolytic Activity. Vol. 41, 401-414. Accepted, .
  • Petrey AC, Qeadan F, Middleton EA, Pinchuk IV, Campbell RA, Beswick EJ (date unknown). Cytokine release syndrome in COVID-19: Innate immune, vascular, and platelet pathogenic factors differ in severity of disease and sex. Vol. 109, 55-66. Accepted, .
  • Campbell RA, Franks Z, Bhatnagar A, Rowley JW, Manne BK, Supiano MA, Schwertz H, Weyrich AS, Rondina MT (date unknown). Granzyme A in Human Platelets Regulates the Synthesis of Proinflammatory Cytokines by Monocytes in Aging. Vol. 200, 295-304. Accepted, .
  • Meidel ZM, Robinson R, Vieira-de-Abreu A, Gormley AJ, Ghandehari H, Grainger D, Campbell RA (date unknown). RGDfk-coated gold nanorods bind only to activated platelets. Vol. 105, 209-21. Accepted, .
  • Schwertz H, Rowley JW, Tolley ND, Campbell RA, Weyrich AS (date unknown). Assessing protein synthesis by platelets. Vol. 788, 141-53. Accepted, .
  • Schwertz H, Rowley JW, Tolley ND, Campbell RA, Weyrich AS (date unknown). Assessing protein synthesis by platelets. Vol. 788, 141-53. Accepted, .
  • Campbell RA, Tolley ND, Schwertz H, Weyrich AS (date unknown). Platelet protein synthesis and translational control. Vol. 8, 200-7. Accepted, .
  • Campbell RA, Aleman M, Gray LD, Falvo MR, Wolberg AS (date unknown). Flow profoundly influences fibrin network structure: implications for fibrin formation and clot stability in haemostasis. (pp. 1281-4). Vol. 104. Accepted, .
  • Bhatlekar S, Jacob S, Manne BK, Guo L, Denorme F, Tugolukova EA, Cody MJ, Kosaka Y, Rigoutsos I, Campbell RA, Rowley JW, O'Connell RM, Bray PF (date unknown). Megakaryocyte-specific knockout of the Mir-99b/let7e/125a cluster lowers platelet count without altering platelet function. (pp. 102624). Vol. 92. Accepted, .
  • Schwertz H, Rowley JW, Portier I, Middleton EA, Tolley ND, Campbell RA, Eustes AS, Chen K, Rondina MT (date unknown). Human platelets display dysregulated sepsis-associated autophagy, induced by altered LC3 protein-protein interaction of the Vici-protein EPG5. (pp. 1534-1550). Vol. 18. Accepted, .
  • Kim SJ, Yao Z, Marsh MC, Eckert DM, Kay MS, Lyakisheva A, Pasic M, Bansal A, Birnboim C, Jha P, Galipeau Y, Langlois MA, Delgado JC, Elgort MG, Campbell RA, Middleton EA, Stagljar I, Owen SC (date unknown). Homogeneous surrogate virus neutralization assay to rapidly assess neutralization activity of anti-SARS-CoV-2 antibodies. (pp. 3716). Vol. 13. Accepted, .
  • Denorme F, Ajanel A, Campbell RA (date unknown). Shining a light on platelet activation in COVID-19. (pp. 1286-1289). Vol. 20. Accepted, .
  • Denorme F, Portier I, Rustad JL, Cody MJ, de Araujo CV, Hoki C, Alexander MD, Grandhi R, Dyer MR, Neal MD, Majersik JJ, Yost CC, Campbell RA (date unknown). Neutrophil extracellular traps regulate ischemic stroke brain injury. Vol. 132. Accepted, .
  • Stoller ML, Basak I, Denorme F, Rowley JW, Alsobrooks J, Parsawar K, Nieman MT, Yost CC, Hamilton JR, Bray PF, Campbell RA (date unknown). Neutrophil cathepsin G proteolysis of protease-activated receptor 4 generates a novel, functional tethered ligand. (pp. 2303-2308). Vol. 6. Accepted, .
  • Sommakia S, Almaw NH, Lee SH, Ramadurai DKA, Taleb I, Kyriakopoulos CP, Stubben CJ, Ling J, Campbell RA, Alharethi RA, Caine WT, Navankasattusas S, Hoareau GL, Abraham AE, Fang JC, Selzman CH, Drakos SG, Chaudhuri D (date unknown). FGF21 (Fibroblast Growth Factor 21) Defines a Potential Cardiohepatic Signaling Circuit in End-Stage Heart Failure. (pp. e008910). Vol. 15. Accepted, .
  • Bounajem MT, Campbell RA, Denorme F, Grandhi R (date unknown). Paradigms in chronic subdural hematoma pathophysiology: Current treatments and new directions. (pp. e134-e141). Vol. 91. Accepted, .
  • Franks ZG, Campbell RA, Weyrich AS, Rondina MT (date unknown). Platelet-leukocyte interactions link inflammatory and thromboembolic events in ischemic stroke. (pp. 11-7). Vol. 1207. Accepted, .
  • Wolberg AS, Campbell RA (date unknown). Thrombin generation, fibrin clot formation and hemostasis. (pp. 15-23). Vol. 38. Accepted, .
  • Vieira-de-Abreu A, Campbell RA, Weyrich AS, Zimmerman GA (date unknown). Platelets: versatile effector cells in hemostasis, inflammation, and the immune continuum. (pp. 5-30). Vol. 34. Accepted, .