Publications

• Bae D, Jones RE & Piscopo KM (2022). Regulation of Blos1 by IRE1 prevents the accumulation of Huntingtin protein aggregates. Molecular biology of the cell. Vol. 33, ar125ar125. Published, 10/01/2022.
• LaBella ML, Hujber EJ, Moore KA, Rawson RL, Merrill SA, Allaire PD, Ailion M, Hollien J, Bastiani MJ & Jorgensen EM (2020). Casein Kinase 1δ Stabilizes Mature Axons by Inhibiting Transcription Termination of Ankyrin. Developmental cell. Vol. 52, 88-103.e6. Published, 01/01/2020.
• Balakrishnan B. & Siddiqi A, Mella J, Lupo A, Li E, Hollien J, Johnson J, Lai K. (2019). Salubrinal enhances eIF2 phosphorylation and improves fertility in a mouse model of Classic Galactosemia. BBA - Molecular Basis of Disease. Vol. 1865, doi: 10.1016/j.bbadis.2019.07.010. Published, 07/2019.
• Bae D, Moore K, Mella J, Hayashi S, Hollien J. Degradation of Blos1 mRNA by IRE1 repositions lysosomes and protects cells from stress. Journal of Cell Biology. 2019. 218(4): 1118-1127. Highlighted in Science Magazine in “Editor’s choice” section, Vol 363, 22 March 2019. Highlighted by F1000Prime Highlighted in JCB Special Collection in Lipid and Membrane Biology, July 2019. Published, 02/2019.
• Lee JE, Morrison W & Hollien J (2018). Hairy and enhancer of split 1 (HES1) protects cells from endoplasmic reticulum stress-induced apoptosis through repression of GADD34. Journal of Biological Chemistry. Vol. doi: 10.1074/jbc.RA118.002124. Published, 02/02/2018.
• Nelson JO, Moore KA, Chapin A, Hollien J & Metzstein MM (2016). Degradation of Gadd45 mRNA by nonsense-mediated decay is essential for viability. eLife. Vol. 5. Published, 04/01/2016.
• Ire1-mediated decay in mammalian cells relies on mRNA sequence, structure, and translational status. Mol Biol Cell. 26(16):2873-84. Published, 06/24/2015.
  http://www.molbiolcell.org/content/early/2015/06/2...
• Drosophila melanogaster Activating transcription factor 4 Regulates Glycolysis during Endoplasmic Reticulum Stress. Published, 02/13/2015.
  http://www.ncbi.nlm.nih.gov/pubmed/25681259
• Sharma AK, Plant JJ, Rangel AE, Meek KN, Anamisis AJ, Hollien J, Heemstra JM. Fluorescent RNA labeling using self-alkylating ribozymes. ACS Chem Biol. 2014;9(8):1680-4. Published, 06/04/2014.
  http://pubs.acs.org/doi/abs/10.1021/cb5002119
• In vivo determination of direct targets of the nonsense-mediated decay pathway in Drosophila. G3 (Bethesda). 2014;4(3):485-96. PMCID: 3962487. Published, 03/20/2014.
  http://www.ncbi.nlm.nih.gov/pubmed/24429422
• Moore KA, Plant JJ, Gaddam D, Craft J, Hollien J. Regulation of sumo mRNA during endoplasmic reticulum stress. PLoS One. 2013. 8(9):e75723. PMCID: 3776770. Published, 03/01/2013.
• Hollien J, Evolution of the unfolded protein response, Biochim Biophys Acta- Molecular Cell Research 1833 (2013) 2458-2463. Published, 03/01/2013.
• Gaddam D, Stevens N, Hollien J. Comparison of mRNA localization and regulation during endoplasmic reticulum stress in Drosophila cells. Mol Biol Cell. 2013. 24(1):14-20. PMCID: 3530775. Published, 01/01/2013.
• Weil D, Hollien J, Cytoplasmic organelles on the road to mRNA decay, Biochim Biophys Acta- Gene Regulatory Mechanisms 1829 (2013) 725-731. Published, 01/01/2013.
• The unfolded protein response in secretory cell function, Annu Rev Genet. Published, 01/2012.
• Regulated Ire1-dependent decay of messenger RNAs in mammalian cells. Hollien J, Lin JH, Li H, Stevens N, Walter P, Weissman JS. J Cell Biol. 2009 Aug 10;186(3):323-31. Published, 08/2009.
• Analysis of Dom34 and its function in no-go decay. Passos DO, Doma MK, Shoemaker CJ, Muhlrad D, Green R, Weissman J, Hollien J, Parker R. Mol Biol Cell. 2009 Jul;20(13):3025-32. Published, 05/2009.
• Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response. Hollien J, Weissman JS. Science. 2006 Jul 7;313(5783):104-7. Published, 07/2006.
• Comparison of the folding processes of T. thermophilus and E. coli ribonucleases H. Hollien J, Marqusee S. J Mol Biol. 2002 Feb 15;316(2):327-40. Published, 02/2002.
• Structural distribution of stability in a thermophilic enzyme. Hollien J, Marqusee S. Proc Natl Acad Sci U S A. 1999 Nov 23;96(24):13674-8. Published, 11/1999.
• A thermodynamic comparison of mesophilic and thermophilic ribonucleases H. Hollien J, Marqusee S. Biochemistry. 1999 Mar 23;38(12):3831-6. Published, 03/1999.

Presentations

• University of Georgia, symposium talk (student-invited). Invited Talk/Keynote, Presented, 03/2020.
• University of Alabama, Birmingham, Cell, Developmental, and Integrative Biology. Invited Talk/Keynote, Presented, 12/04/2019.
• University of California, San Francisco, Biochemistry and Biophysics (premier basic science seminar series). Invited Talk/Keynote, Presented, 11/12/2019.
• Membrane trafficking symposium. Invited Talk/Keynote, Presented, 07/2019.
• Research talk at FASEB conference “From unfolded proteins to disease”. Invited Talk/Keynote, Presented, 06/20/2019.
• Annual meeting for the American Society of Cell Biology (ASCB), minisymposium talk. Invited Talk/Keynote, Presented, 12/2018.
• chemistry department research seminar. Invited Talk/Keynote, Presented, 09/2018.
• International conference, “Proteostasis”, Ericeira, Portugal . Invited Talk/Keynote, Presented, 11/2017.
• FASEB summer conference, “From unfolded proteins in the ER to disease”. Invited Talk/Keynote, Presented, 06/2017.
• University of California, San Diego and Scripps Institute seminar. Invited Talk/Keynote, Presented, 08/2016.
• CSHL meeting, Protein Homeostasis in Health and Disease (poster presented by J. Hollien). Poster, Presented, 06/2016.
• Hollien and Moore, Regulated Ire1-dependent decay of mRNAs affects lysosome positioning and function during ER stress, CSHL meeting. Presentation, Presented, 06/2016.
• Lee and Hollien, HES1 protects cells from ER stress-induced apoptotic cell death, CSHL meeting, Protein Homeostasis in Health and Disease (poster presented by J. Lee). Presentation, Presented, 06/2016.
• International Symposium, "ER Stress" University of Ghent, Belgium. Invited Talk/Keynote, Presented, 06/2015.
• 2010 EMBO conference, “Toward a comprehensive understanding of ER functions”. Invited Talk/Keynote, Presented, 10/2010.