EDWARD W HSU portrait
  • Associate Professor, Biomedical Engineering

Publications

  • Li DS, Avazmohammadi R, Rodell CB, Hsu EW, Burdick JA, Gorman JH, Gorman RC & Sacks MS (2021). How hydrogel inclusions modulate the local mechanical response in early and fully formed post-infarcted myocardium. Acta biomaterialia. Vol. 114, 296-306. Published, 02/01/2021.
  • Pritz MB, Ziegler LC, Thompson TN & Hsu EW (2020). Magnetic resonance diffusion tensor tractography of a midbrain auditory circuit in Alligator. Neuroscience letters. Vol. 738, 135251. Published, 11/01/2020.
  • Li DS, Avazmohammadi R, Merchant SS, Kawamura T, Hsu EW, Gorman JH, Gorman RC & Sacks MS (2020). Insights into the passive mechanical behavior of left ventricular myocardium using a robust constitutive model based on full 3D kinematics. Journal of the mechanical behavior of biomedical materials. Vol. 103, 103508. Published, 07/01/2020.
  • Jeong KE, Hsu EW & Jeong EK (2020). Diffusion MRI using two-dimensional single-shot radial imaging (2D ss-rDWI) with variable flip angle and random view ordering. Magnetic resonance imaging. Vol. 61, 273-284. Published, 01/01/2020.
  • Sun CY, Zhu YM, Chu CY, Yang F, Liu WY, Korenberg JR, Hsu EW. Assessmet of the characteristics of orientation distribution functions in HARDI using morphological metrics. PLOS One. 11:e0150161, 2016.. Published, 10/2016.
  • Abdullah OM, Seidel T, Dahl M, Gomez AD, Yiep G, Cortino J, Sachse FB, Albertine KH, Hsu EW. Diffusion tensor imaging and histology of developing hearts. NMR Biomed. 29:1338-49, 2016.. Published, 10/2016.
  • Merchant SS, Gomez AD, Morgan JL, Hsu EW. Parametric modeling of the mouse left ventricular myocardial fiber structure. Ann Biomed Eng. 44:2261-73, 2016.. Published, 10/2016.
  • Merchant SS, Kosaka Y, Yost HJ, Hsu EW, Brunelli L. Micro-computed tomography for the quantitative 3-dimensional assessment of the compact myocardium in the mouse embryo. Circ J. 80:1795-803, 2016.. Published, 10/2016.
  • Abdullah OM, Gomez AD, Merchant S, Heidinger M, Poelzing S, Hsu EW. Orientation dependence of microcirculation-induced diffusion signal in anisotropic tissues. Magn. Reson. Med. 76:1252-62, 2016.. Published, 10/2016.
  • Abdullah OM, Seidel T, Dahl M, Gomez AD, Yiep G, Cortino J, Sachse FB, Albertine KH, Hsu EW. Diffusion tensor imaging and histology of developing myocardium. International Society of Magnetic Resonance in Medicine 24rd Annual Meeting, Singapore, May 2016. Published, 05/2016.
  • Van Zeeland YRA, Schoemaker NJ, Hsu EW. Advances in diagnostic imaging. Speer BL (ed.) Current Therapy in Avian Medicine and Surgery. St. Louis, MO: Elsevier. 2015. Published, 12/2015.
  • Abdullah OA, Gomez AD, Merchant S, Heidinger M, Poelzing S, Hsu EW. Orientation dependence of microcirculation induced diffusion signal in anisotropic tissues. American Heart Association Scientific Sessions. Orlando, FL. November 2015. Published, 11/2015.
  • Sun CY, Chu CY, Liu WY, Hsu EW, Korenberg JR & Zhu YM (2015). Quantitative representation and description of intravoxel fiber complexity in HARDI. Physics in medicine and biology. Vol. 60, 8417-36. Published, 10/01/2015.
  • David Gomez A, Bull DA & Hsu EW (2015). Finite-Element Extrapolation of Myocardial Structure Alterations Across the Cardiac Cycle in Rats. Journal of biomechanical engineering. Vol. 137, 101010. Published, 09/01/2015.
  • Welsh CL, DiBella EV & Hsu EW (2015). Higher-Order Motion-Compensation for In Vivo Cardiac Diffusion Tensor Imaging in Rats. IEEE transactions on medical imaging. Vol. 34, 1843-53. Published, 09/01/2015.
  • Abdullah OA, Gomez AD, Schmidt A, Hsu EW. Anisotropy of microcirculation-induced MRI signal organized tissues: finite-element modeling and validation in perfused hearts. Summer Biomechanics, Bioengineering and Biotransport Conference (SB3C). Snowbird, UT, June 2015.. Published, 06/2015.
  • Abdullah OA, Gomez AD, Merchant S, Heidinger M, Poelzing S, Hsu EW. Orientation dependence of microcirculation induced diffusion signal in anisotropic tissues. International Society of Magnetic Resonance in Medicine 23rd Annual Scientific Meeting, Toronto, Canada, May 2015. Published, 05/2015.
  • McKellar SH, Javan H, Bowen ME, Liu X, Schaaf CL, Briggs CM, Zou H, Gomez AD, Abdullah OM, Hsu EW & Selzman CH (2015). Animal model of reversible, right ventricular failure. The Journal of surgical research. Vol. 194, 327-33. Published, 03/01/2015.
  • Gomez AD, Zou H, Shiu YT, Hsu EW. Characterization of regional deformation and material properties of the intact explanted vein by microCT and computational analysis. Cardiovasc. Eng. Technol. 5: 359-370, 2014. Published, 12/2014.
  • Abdullah OM, Drakos SG, Diakos NA, Wever-Pinzon O, Kfoury AG, Stehlik J, Selzman CH, Reid BB, Brunisholz K, Verma DR, Myrick C, Sachse FB, Li DY, Hsu EW. Characterization of diffuse fibrosis in the failing human heart via diffusion tensor imaging and quantitative histological analysis. NMR Biomed. 27: 1378-1386, 2014. Published, 11/2014.
  • Gomez AD, Merchant SS, Hsu EW. Accurate high-resolution measurements of 3D tissue dynamics with registration-enhanced displacement encoding MRI. IEEE Trans. Med. Imag. 33: 1350-1362, 2014. Published, 06/2014.
  • Welsh, CL, Hsu EW, Adluru G, DiBella EVR. Accelerating Diffusion Kurtosis Acquisition using SIR and Model-Based Reconstruction. International Society of Magnetic Resonance in Medicine 22nd Annual Scientific Meeting, Milan, Italy, May 2014. Published, 05/2014.
  • Welsh CL, DiBella EVR, Hsu EW. Analysis and Design of Higher-Order Motion-Compensated Diffusion Encoding Schemes for In Vivo Cardiac DTI. International Society of Magnetic Resonance in Medicine 22nd Annual Scientific Meeting, Milan, Italy, May 2014. Published, 05/2014.
  • Abdullah, OM., Drakos, SG., Diakos, NA., Wever-Pinzon, O., Kfoury, AG., Stehlik, J., Selzman, CH., Reid, B., Brunisholz, K., Verma, DR., Myrick, C., Li, DY., Hsu, EW. DTI and Quantitative Histological Correlation of Diffuse Fibrosis in Failing Hearts. International Society of Magnetic Resonance in Medicine 22nd Annual Scientific Meeting, Milan, Italy, May 2014. Published, 05/2014.
  • Merchant SS, Gomez AD, Hsu EW. Parametric representation, variability analysis and atlas construction of the mouse myocardial fiber structure. International Society of Magnetic Resonance in Medicine 22nd Annual Scientific Meeting, Milan, Italy, May 2014. Published, 05/2014.
  • McKellar SH, Liu Annie MD, Nelson N, Schaaf C, Zhou D, Abdullah O, Gomez AD, Whitehead K, Selzman C, Hsu EW. An Animal Model of Chronic, Pressure-Overload Right Ventricular Failure to Study Cardiac Failure and Recovery. 2014 Academic Surgical Congress (ASC), San Diego, CA, February 2014. Published, 02/2014.
  • Abdullah O, Gomez AD, Welsh CL, Hsu EW. Mapping Myocardial Fiber Structure using Diffusion Tensor Imaging. In C. Constantinides (Ed.), Latest Advances in Clinical and Pre-Clinical Cardiovascular Magnetic Resonance Imaging Amsterdam, The Netherlands: Bentham, 2013: pp. 199–223. Published, 11/2013.
  • Gomez AD, Merchant SS, Hsu EW. A Hybrid Method for Automatic Recosntruction of 3D Tissue Displacement Fields from MRI. Biomedical Engineering Society (BMES) Annual Conference, Seattle, WA, September 2013. Published, 09/2013.
  • Gomez AD, Watson B, Li H, Zhuplatov I, Hsu EW, Shiu Y-T. High-Resolution Characterization of Vein Deformation Under Arterial Blood Pressure. Biomedical Engineering Society (BMES) Annual Conference, Seattle, WA, September 2013. Published, 09/2013.
  • Welsh CL, DiBella EVR, Adluru G, Hsu EW. Model based reconstruction of undersampled diffusion tensor k-space data. Magn. Reson. Med. 70: 429-440, 2013. Published, 08/2013.
  • Lee LC, Wenk JF, Zhong L, Klepach D, Zhang Z, Ge L, Ratcliffe MB, Zohdi TI, Hsu EW, Navia JL, Kassab GS, Guccione JM. Analysis of patient-specific surgical ventricular restoration: importance of an elliposoidal left ventricular geometry for diastolic and systolic function. J Appl Physiolol. 115: 136-44, 2013. Published, 07/2013.
  • Abdullah O, Gomez AD, Merchant S, Stedham O, Heidinger M, Poelzing S, Hsu E. Effects of Perfusion on Cardiac MR Diffusion Measurements. International Society of Magnetic Resonance in Medicine 21st Annual Scientific Meeting,. Salt Lake City, UT, May 2013. Published, 05/2013.
  • Gomez AD, Merchant SS, Hsu EW, Registration-Enhanced Reconstruction of DENSE-MRI Tissue Displacement Fields. Proceedings of the 11th International Symposium, Computer Methods in Biomechanics and Biomedical Engineering (CMBBE), Salt Lake City, Utah, April 2013. Published, 04/2013.
  • Towner RA, Gillespie DL, Schwager A, Saunders DG, Smith N, Nijoku CE, Krysiak RS, Larabee C, Iqbal H, Floyd RA, Bourne DWA, Abdullah O, Hsu E, Jensen RL. Regression of glioma tumor growth in F98 and U87 rat glioma models by the Nitrone OKN-007. Neoru Oncol. 15: 330-40, 2013. Published, 03/2013.
  • Elia R, Newhide DR, Pedevillano PD, Reiss GR, Firpo MA, Hsu EW, Kaplan DL, Pretwich GD, Peattie RA. Silk-hyaluronan-based composite hydrogels: A novel, securable vehicle for drug delivery. J Biomater Appl. 27: 749-62, 2013. Published, 02/2013.
  • Turner RA, Wauthier E, Lozoya O, McClelland R, Bowsher JE, Barbier C, Prestwich G, Hsu E, Gerber DA, Reid LM. Successful transplantation of human hepatic stem cells with restricted localization to liver using hyaluronan grafts. Hepatology. 57: 775-84, 2013. Published, 02/2013.
  • Merchant S, Jiang Y. Joshi S. Hsu EW. Assessment of Variability of the Mouse Myocardial Fiber Structure via Principal Component Analysis. The 13th International Conference on Bioinformatics & Computational Biology. Las Vegas, 2012. Published, 06/2012.
  • Abdullah O, Hsu EW. Diffusion Tensor Imaging of Normal and Ablated Cardiac Left Atrial Specimens. International Society of Magnetic Resonance in Medicine 20th Annual Scientific Meeting, Melbourne, Australia, 2012. Published, 05/2012.
  • Watson BR, Hsu EW. Effects of Formalin Fixation on Diffusion Tensor Imaging of Myocardial Tissues. International Society of Magnetic Resonance in Medicine 20th Annual Scientific Meeting, Melbourne, Australia, 2012. Published, 05/2012.
  • Welsh CL, Hsu EW, Adluru G, Anderson JS, DiBella EVR. Quantitative Performance Comparison of Reconstruction Methods for Multi-Coil DTI Data. International Society of Magnetic Resonance in Medicine 20th Annual Scientific Meeting, Melbourne, Australia, 2012. Published, 05/2012.
  • McClelland R, Wauthier E, Thallheden T, Reid LM, Hsu EW. In Situ labeling and magnetic resonance imaging of transplanted human hepatic stem cells. Mol Imaging Biol. 13: 911, 2011. Published, 10/2011.
  • Elias R, Newhide DR, Pedevillano PD, Reiss GR, Firpo MA, Hsu EW, Kaplan DL, Prestwich GD, Peattie RA. A novel securable hyaluronic acid-silk hydrogel composite for controlled drug release. Biomedical Engineering Society 2011 Annual Meeting. Hartford, CT, 2011. Published, 09/2011.
  • Welsh CL, DiBella EVR, Hsu EW. Model-Based Reconstruction of Undersampled DTI Data. International Society of Magnetic Resonance in Medicine 19th Annual Scientific Meeting, Montreal, Canada, 2011. Published, 05/2011.
  • Welsh CL, Hsu EW. DiBella EVR. Strategies of Undersampling and Reconstructing Undersampled MR DTI Data. International Symposium in Biomedical Imaging, Chicago, IL, 2011. Published, 05/2011.
  • OM Abdullah, SG Drakos, DR Verma, J Stehlik, AG Kfoury, CH Selzman, C Myrick, G Russel, DY Li, and E. W. Hsu. Characterization of the Failing Human Heart via Diffusion Tensor Imaging: an Ex-Vivo Study. International Society of Magnetic Resonance in Medicine 19th Annual Scientific Meeting, Montreal, Canada, 2011. Published, 05/2011.
  • Jiao F, Phillips JM, Stinstra J, Kroger J, Varma R, Hsu E, Korenberg J, Johnson CR. Metrics for uncertainty analysis and visualization of diffusion tensor images. Lect Notes Comput Sci.6326: 179, 2010. Published, 10/2010.
  • Deren KE, Packer M, Forsyth J, Milash B, Abdullah OM, Hsu EW, McAllister JP 2nd. Reactive astrocytosis, microgliosis and inflammation in rats with neonatal hydrocephalus. Exp Neurol. 226: 110-9, 2010. Published, 08/2010.
  • Lee JN, Hsu EW, Rashkin E, Thatcher JW, Kreitshitz S, Gale P, Healy L, Marchand WR. Reliability of fMRI motor tasks in structures of the corticostriatal circuitry: implications for future studies and circuit function. Neuroimage, 49: 1282-8, 2010. Published, 04/2010.
  • Marchand WR, Lee JN, Healy L, Thatcher JW, Rashkin E, Starr J, Hsu EW. An fMRI motor activation paradigm demonstrate abnormalities of putamen activation in females with panic disorder. Journal of Affective Disorders. Published, 2009.
  • EW Hsu, LJ Healy, DR Einstein, AP Kuprat. Imaging-based assessment and modeling of the structures of the myocardium. JM Guccione, GS Kassab, MB Ratcliffe (editors), Computational Cardiovascular Mechanics – Modeling and Applications in Heart Failure. New York: Springer, 2009: pp. 23-40. Published, 2009.
  • Deren KE, Forsyth J, Abdullah O, Hsu EW, Klinge PM, Silverberg GD, Johanson CE, McAllister JP 2nd. Low levels of amyloid-beta and its transporters in neonatal rats with and without hydrocephalus. Cerebrospinal Fluid Res, 6: 4, 2009. Published, 2009.
  • Lee JN, Hsu EW, Rashkin E, Thatcher JW, Kreitshitz S, Gale P, Healy L, Marchand WR. Reliability of fMRI motor tasks in structures of the corticostriatal circuitry: implications for future studies and circuit function. Neuroimage, 49: 1282-8, 2010. Published, 2009.
  • Marchand WR, Lee JN, Thatcher JW, Hsu EW, Rashkin E, Suchy Y, Celune G, Starr J, Barbera SS. Putamen coactivation during motor task execution. Neuroreport, 19: 957 - 960, 2008. Published, 2008.
  • Nettles DL, Kitaoka K, Hanson NA, Flahiff CM, Mata BA, Hsu EW, Chilkoti A, Setton LA. In situ crosslinking elastin-like polypeptide gels for application to articular cartilage repair in a goat osteochondral defect model. Tissue Engineering Part A 14: 1133 - 1140, 2008. Published, 2008.
  • Walker JC, Ratcliffe, MB, Zhang P, Wallace AW, Hsu EW, Saloner D, Guccione JM. MRI-based finite-element stress analysis after linear repair of left ventricular aneurysm. J. Thoracic Cardiov. Surg. 135: 1094 - 1102, 2008. Published, 2008.

Presentations

  • "Small Animal Imaging Technology for Preclinical Research" American Association for Laboratory Animal Science District 8 2010 Meeting. May, 2010. Invited Talk/Keynote, Presented, 05/2010.
  • OM Abdullah, JW Yockman, CM Straub, N Hu, A Albinil, SW Kim, DA Bull, EW Hsu. Evaluation of Acute Myocardial Ischemia Gene Therapy Efficacy Using Diffusion Tensor Imaging. International Society of Magnetic Resonance in Medicine 17th Scientific Meeting 2009, Honolulu, May, 2009. Conference Paper, Refereed, Presented, 2009.
  • EW Hsu. Imaging based structural models of the myocardium. Fall 2009 NHLBI-VCU Workshop on Computational Cardiovascular and Cardiopulmonary Dynamics, Richmond, VA. Invited Talk/Keynote, Presented, 2009.
  • Marchand WR, Lee JN, Thatcher JW, Hsu EW, Rashkin E, Suchy Y, Chelune G, Starr J, Barbera SS. Putamen Activation and Connectivity during Task Execution Suggests a Mechanism for the Etiology of Motor Symptoms in Psychiatric Disorders [Abstract]. Biological Psychiatry, 63 (supplement 1), 75S, 2008. Conference Paper, Presented, 2008.
  • Healy L, Joshi S, Jiang Y, Hsu E. Interspecies variability in the myocardial fiber structure acquired using MR diffusion tensor imaging. International Society of Magnetic Resonance Sixteenth Scientific Meeting, Toronto, Canada, May, 2008. Conference Paper, Presented, 2008.
  • Marchand WR, JN Lee, Thatcher JW, Healy L, Hsu EW, Rashkin E, Starr J. Bilateral putamen connectivity during human motor task execution. Forty-first Annual Winter Conference on Brain Research. Snowbird, Utah, January, 2008. Conference Paper, Other, 2008.
  • Shi Y, Joshi S, Lee JN, Marchand WR, Rashkin E, Hsu EW. Reproducibility of fractional anisotropy and mean diffusivity in diffusion tensor imaging at 3.0 T. International Society of Magnetic Resonance Sixteenth Scientific Meeting, Toronto, Canada, May, 2008. Conference Paper, Presented, 2008.
  • Healy L, Joshi S, Jiang Y, Hsu E. Interspecies variability in the myocardial fiber structure acquired using MR diffusion tensor imaging. International Society of Magnetic Resonance Sixteenth Scientific Meeting, Toronto, Canada, May, 2008. Conference Paper, Presented, 2008.
  • Jiang Y, Joshi S, Pandya K, Smithies O, Hsu EW. A study of variability of the mouse myocardial fiber structure obtained by MR diffusion tensor imagng. International Society of Magnetic Resonance Sixteenth Scientific Meeting, Toronto, Canada, May, 2008. Conference Paper, Presented, 2008.
  • Marchand WR, Lee JN, Thatcher JW, Hsu EW, Rashkin E, Suchy Y, Chelune G, Starr J, Barbera SS. (2008) Putamen functional connectivity demonstrates a mechanism for the integration of motor and cognitive symptoms as well as cerebellar-basal ganglia communication. Human Brain Mapping, Melbourne, Australia, 2008. Conference Paper, Presented, 2008.
  • “Pushing the Frontiers of Diffusion Tensor Imaging” IEEE Asimomar Conference on Signals, Systems and Computers, Monterey, CA, October, 2008. Invited Talk/Keynote, Presented, 2008.
  • “Small Animal MRI: Technical Considerations”, University of Utah Brain Institute Symposium, April, 2008. Invited Talk/Keynote, Presented, 2008.
  • “Assessments of Myocardial Fiber Structure using Magnetic Resonance Diffusion Tensor Imaging”, University of Utah Cardiology Grand Rounds, April, 2008. Invited Talk/Keynote, Presented, 2008.

Grants, Contracts & Research Gifts

  • Engineering an angiogenic cardiac patch. PI: R. Peattie. 10/01/2009 - 09/30/2012. Total project budget to date: $0.00
  • A computational framework for mapping long range genetic circuits. PI: J Korenberg and T Tasdizen. NIH RC1, 09/30/2009 - 09/29/2011. Total project budget to date: $0.00