Bellamkonda K. KISHORE, M.D., PhD., MBA, CBiol, FASN, FRSB, FAPS, FAHA portrait
  • Adjunct Professor, Internal Medicine, School of Medicine
  • Adjunct Associate Professor, Nutrition & Integrative Physiology, College of Health
  • Member, Center on Aging, Internal Medicine, School of Medicine
  • President, CEO & CSO, ePurines, Inc, University of Utah Research Park

Research Keywords

  • Pathophysiology of Acquired Nephrogenic Diabetes Insipidus
  • Role of Purinergic Signaling in Renal Physiology
  • Pathophysiology and Experimental Therapeutics
  • Diet-Induced Obesity and Insulin Resistance
  • Induction of Native Erythropoietin Production in the Kidney

Presentations

  • Purinergic Regulation of Renal Water and Sodium Transport at the Tulane Hypertension and Renal Center for Excellence, Tulane University, New Orleans, LA. , , 2012.
  • Purinergic Regulation of Renal Water Transport: Physiology, Pathophysiology and Experimental Therapeutics at the Vascular Biology Center, Gerogia Health Sciences University, Augusta, GA. , , 2012.
  • Purinergic Regulation of Renal Water Transport, at the Symposium on Purinergic Signaling in the Kidney, Purines 2008 International Conference, Copenhagen, Denmark. , , 2008.
  • Purinergic Regulation of Renal Water Transport: From Molecules to Bedside at the Christian de Duve Institute of Cellular Pathology, Brussels, Belgium. , , 2008.
  • Purinergic Regulation of Renal Water Transport: Physiology and Pathophysiology and Therapeutic Implications. Department of Pharmaceutical Chemistry, University of Bonn, Bonn, Germany. , , 2007.
  • Interaction of Purinergics with Prostanoids and Vasopressin in the Collecting Duct: Physiology and Pathophysiology, at the Symposium on Emerging Insights into the Purinergic Signaling in Renal, Pulmonary and Microvascular Physiology and Pathophysiology, Experimetnal Biology 2007, Washington DC. , , 2007.
  • Listhrop R, Nelson RD, Ecelbarger CA, Kohan DE, Kishore BK. Genetic deletion of P2Y2 receptor alters the protein abundances of renal sodium transporters and channels. Renal Section 2007 Young Investigator Award Session at the Experimental Biology 2007 meeting, Washington DC. , , 2007.
  • Kishore BK, Sands JM, Kohan DE, Martin CF, Ge Y, Nelson RD, Klein JD. Increased urinary concentrating ability of P2Y2 receptor null mice is associated with marked increase in protein abundances of AQP2 and UT-A1 in renal medulla. Renal Section 2007 Young Investigator Award Session at the Experimental Biology 2007, Washington DC. , , 2007.
  • Lecture on Purinergic Control of Water Transport in Kidney, Division of Nephrology, George Washington University School of Medicine and the V.A. Medical Center, Washington DC. , , 2000.
  • Seminar on Physiology and Pathophysiology of Nucleotide Receptors, the Potential Drug Targets, Department of Pharmacology and Cell Biophysics, University of Cincinnati Medical Center, Cincinnati, OH. , , 2000.
  • Seminar on Altered Expression of Renal Aquaporins and Solute Transporters in Toxic Nephropathy: Cisplatin and Gentamicin. Unit of Cellular and Molecular Pharmacology, Faculty of Medicine, Catholic University of Louvain, Brussels, Belgium. , , 2000.
  • Seminar on Purinergic Control of Water Transport in Kidney: Physiology and Pathophysiology. Discovery Group, Inspire Pharmaceuticals, Inc., Durham, NC. , , 2000.
  • Seminar on Aquaporin Water Channels: Physiology and Pathophysiology. Department of Biology, School of Biological Sciences and Department of Cellular Physiology, School of Medicine, Wright State University, Dayton, OH. , , 2000.
  • Renal Research Conference on Purinergic Control of Water Transport in Kidney: Physiology and Pathophysiology, Division of Nephrology, Dept. of Medicine, Indiana University School of Medicine, Indianapolis, IN. , , 1999.
  • From Molecules to Bedside, Internal Medicine Research Seminar series, on Purinergic Control of Water Transport in Kidney: Physiology and Pathophysiology, University of Cincinnati Medical Center, Cincinnati, OH. , , 1999.
  • Internal Medicine Research Conference on Aquaporin Water Channels in Kidney: Physiology and and Pathophysiology, University of Cincinnati Medical Center, Cincinnati, OH. , , 1998.
  • Lecture on Physiological and Molecular Approaches to the Study of Expression and Regulation of Aquaporin-2 Water Channel in the Kidney, Div. of Nephrology & Hypertension, Univ. of Cincinnati Medical Center, Cincinnati, OH. , , 1996.
  • Symposium Lecture on Aminoglycoside Nephrotoxicity at the Symposium on Drug Nephrotoxicity, Fifth Asian Pacific Congress of Nephrology, New Delhi, India. , , 1992.
  • Lecture on Aminoglycoside-induced Nephrotoxicity: Mechanism of Protection Afforded by Poly-L-Aspartic Acid, Dept. of Toxicology and Occupational Medicine, Institute of Occupational Health, Dortmund, Germany. , , 1989.
  • Seminar on Gentamicin Nephrotoxicity: Mechanism of Protection Afforded by Poly-L-Aspartic Acid, Dept. of Nephrology, Walter Reed Army Medical Center, WRAIR, Washington DC. , , 1989.
  • Seminar on Inhibition of Aminoglycoside-induced Nephrotoxicity by Polyanionic Peptides: Biochemical and Morphological Studies, Dept. of Nephrology and Hypertension, Louisiana State University Medical Center, Shreveport, LA. , , 1989.
  • Kishore BK, Peti-Peterdi J, Liu T, Riquier-Brison A, Carlson NG, Zhang Y. Genetic deletion of P2y2 receptor suppresses lithium-induced medullary collecting duct remodeling in mice. Experimental Biology 2018 meeting, Sand Diego, CA. , , 2018.
  • Zhang Y, Muller CE, Liu T, Brandes AU, Kishore BK. Potential impact of adenine (P0) receprors on urinary albumin/creatinine raio in CKD. Kidney Week 2017 of the American Society of Nephrology, New Orleans, LA. , , 2017.
  • Kishore BK, Hansson KM, Liu T, Magnelle K, Carlson NG, Zhang Y. Renal phenotype of P2Y12 receptor knockout mice. Kidney Week 2017 of the American Society of Nephrology, New Orleans, LA. , , 2017.
  • Kishore BK, Brandes AU, Carlson NG, Zhang Y. Prasugrel suppresses development of lithium-induced nephrogenic diabetes insipidus in mice. Experimental Biology 2016 meeting, San Diego, CA. , , 2016.
  • Zhang Y, Ecelbarger CM, Muller CE, Brandes AU, Liu T, Lesniewski L, Kishore BK. Role of P2Y2 recceptor in adipogenesis and metabolism. Kidney Week 2016 of the American Society of Nephrology, Chicago, IL. , , 2016.
  • Kishore BK, Carlson NG, Hansson KM, Zhang Y. Genetic deletion of ADP-activated P2y12 receptors ameliorate lithium-induced NDI in mice. Kidney Week 2016 of the American Society of Nephrology, Chicago, IL. , , 2016.
  • Brandes AU, Zhang Y, Robson SC, Kishore BK. Attenuated response of hCD39 overexpressing transgenic mice to high-faat diet-induced obesity and gluclose tolerance. Experimental Biology 2016 meeting, San Diego, CA. , , 2016.
  • Kishore BK, Zhang Y, Heiney KM, Ecelbarger CM. P2Y2 receptor facilitates high-fat diet induced insulin resistance. Experimetnal Biology 2015 meeting, Boston, MA. , , 2015.
  • Brandes AU, Zhang Y, Heiney KM, Robson SC, Kishore BK. Transgenic mice overexpressing human CD39 (ENTPD1) are protected from high-fat diet-induced obesity and insulin resistance. Accepted for poster presentation at the Kidney Week 2015 of the American Society of Nephrology, San Diego, CA. , , 2015.
  • Zhang Y, Heiney KM, Kishore BK. Effect of concurrent P2Y2 receptor deletion and P2Y12 receptor blockade on lithium-induced nephrogenic diabetes insipidus in mice. Accepted for oral presentation at the Kidney Week 2015 of the American Society of Nephrology, San Diego, CA. , , 2015.
  • Heiney KM, Zhang Y, Strasburg DL, Carlson NG, Kohan DE, Kishore BK. Genetic deletion of P2Y2 receptor offers long-term (5 mo) protection against lithium-induced polyuria, natriuresis and kaliuresis. Kidney Week 2014 of the American Society of Nephrology, Philadelphia, PA. , , 2014.
  • Zhang Y, Ecelbarger CM, Kishore BK. Genetic deletion of P2Y2 receptor confers significant resistance to development of diet-indued obesity and improves glucose tolerance. Abstract accepted for presentation at the Kidney Week 2013 of the American Society of Nephrology, Atlanta, GA. , , 2013.
  • Kishore BK, Peti-Peterdi J, Villanueva KG, Strasburg DL, Carlson NG, Kohan DE, Zhang Y. P2Y12 receptor protein is co-localized with AQP2 in the collecting duct principal cells of rat and mouse. Abstract accepted for presentation at the Kidney Week 2013 of the American Society of Nephrology. , , 2013.
  • Zhagn Y, Carlson NG, Kishore BK, Eelbarger CM. Pharmacolgoical blockade of P2Y12 reeptor revereses lithium-induced downregulation of NKCC2, NCC and α-ENaC protein abundances in mice. Abstract accepted for presentation at the Kidney Week 2013 of the American Society of Nephrology. , , 2013.
  • Zhang Y, Baqi Y, Carlson NG, Kohan DE, Muller CE, Kishore BK. Pharmacological blockade of ADP-activated P2Y12 receptor in rat IMCD potentiates dDAVP-induced AQP2, AQP3 and V2 receptor. Abstract accepted for presentation at the Kidney Week 2013 of the American Society of Nephrology, Atlanta, GA. , , 2013.
  • Zhang Y, Baqi Y, Carlson NG, Kohan DE, Muller CE, Kishore BK. Pharmacological blockade of ADP-activated P2Y12 receptor in rat IMCD potentiates dDAVP-induced AQP2, AQP3 and V2 receptor. Kidney Week 2013 of the American Society of Nephrology, Atlanta, GA. , , 2013.
  • Kishore BK, Peti-Peterdi J, Villanueva KG, Strasburg DL, Carlson NG, Kohan DE, Zhang Y. P2Y12 receptor protein is co-localized with AQP2 in the collecting duct principal cells of rat and mouse. Kidney Week 2013 of the American Society of Nephrology, Atlanta, GA. , , 2013.
  • Zhang Y, Carlson NG, Kishore BK, Eelbarger CM. Pharmacolgoical blockade of P2Y12 reeptor revereses lithium-induced downregulation of NKCC2, NCC and α-ENaC protein abundances in mice. Kidney Week 2013 of the American Society of Nephrology, Atlanta, GA. , , 2013.
  • Zhang Y, Robson SC, Morris KL, Dwyer KM, Kishore BK., Eelbarger CM. Impaired aldosterone excape in transgenic mice over-expressing human CD39: Role of altered sodium transporter regulation. Presented at the Kidney Week 2012 of the American Society of Nephrology, San Diego, CA. , , 2012.
  • Kishore BK, Zhang Y, Morris KL, Dwyer KM, Robson SC. Impaired vasopressin escape in transgenic mice over-expressing human CD30: Role of prostaglandins. Presented at the Kidney Week 2012 of the American Society of Nephrology, San Diego, CA. , , 2012.
  • Peti-Peterdi J, Zhang Y, Gevorgyan H, Kohan DE, Muller CE. Kishore BK. Functional expression of P0 (adenine) receptor in the collecting duct intercalated cells in rat an dmouse. Presented at the Kidney Week 2012 of the American Society of Nephrology, San Diego, CA. , , 2012.
  • Kishore BK, Zhang Y, Pop IL, Gevorgyan H, Muller CM, Peti-Peterdi J, Cellular localization of P0 (adenine) receptor in rat kidney. Presented at the Experimetnal Biology 2012 meeting, San Diego, CA. , , 2012.
  • Kishore BK, Pop IL, Carlson NG, Zhang Y. Pharmacological blockade of P2Y12 receptor ameliorates lithium-induced polyuria in rats. Presented at the Kidney Week 2011 of the American Society of Nephrology, Philadelphia, PA. , , 2011.
  • Pop IL, Zhang Y, Carlson NG, Kishore BK. Altered prostanoid receptor signaling, but mot decreased PGE2 production explains the significant resistance of P2Y2 nill mice to Li-indued polyuria. Presented at the Kidney Week 2011 of the American Society of Nephrology, Philadelphia, PA. , , 2011.
  • Kishore BK, Pop IL, Carlson NG, Zhang Y. Pharmacological blockade of P2Y12 receptor ameliorates lithium-induced poluria in rats. Presented at the Kidney Week 2011 of the American Society of Nephrology, Philadelphia, PA. , , 2011.
  • Zhang Y, Pop IL, Carlson NG, Kishore BK. Pharmacological blockade of P2Y12 receptor increases urinary concentration in rats. Presented at the Kidney Week 2011 of the American Society of Nephrology, Philadelphia, PA. , , 2011.
  • Kishore BK, Sands JM, Zhang Y, Martin CF, Klein JD. Mice lacking P2Y2 receptor are resistant to potassium(K)-depletion induced polyuria. Presented at the Kidney Week 2010 of the American Society of Nephrology, Denver, CO. , , 2010.
  • Kishore BK, Sands JM, Zhang Y, Martin CF, Klein JD, Mice lacking P2Y2 receptor are resistant to potassium(K)-depletion insuced polyuria. Presented at the Kidney Week 2010 of the American Society of Nephrology, Denver, CO. , , 2010.
  • Zhang Y, Enjyoji K, Morris KL, Sparrow SK, Dwyer KM, Robson SC, Kishore BK. Renal phenotype of transgenic mice over-expressing hCD39/NTDPase1. Presented at the Kidney Week 2010 of the American Society of Nephrology, Denver, CO. , , 2010.
  • Klein JD, Sand JM, Martin CF, Zhang Y, Kishore BK. Transporters and urine concentration in low-protein fed mice with P2Y2 receptor knock-out. Presented at the Kidney Week 2010 of the American Society of Nephrology, Denver, CO. , , 2010.
  • Kishore BK, Schmidt G. Application of principles and metrics of operations management to water processing in the kidney. Presented at the Experimental Biology 2010 meeting, Anaheim, CA. , , 2010.
  • Kishore BK, Nelson RD, Kohan DE, Carlson NG, Zhang Y. Characterization of resistance of P2Y2 receptor knockout mice to lithium-induced nephrogenic diabetes insipidus. Presened at the 42nd Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2009.
  • Kishore BK, Zhang Y, Westenfelder C. Poly-D-glutamaic acid induced expansion of erythropoietin-producing cells in the rat kidney is associated with decreased expression of pro-inflammatory and pro-fibrotic genes. Presented at the 42nd Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2009.
  • Zhang Y, Kohan DE, Nelson RD, Carlson NG, Kishore BK. Potential involvement of P2Y2 receptor in the diuresis of post-obstructive uropathy in rats. Presented at the 42nd Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2009.
  • Kishore BK, Carlson NG, Kamareth CD, Zhang Y. Potential involvement of P2Y2 and P2Y4 receptors in lithium-induced polyuria. Presented at the 41st Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2008.
  • Zhang Y, Kohan DE, Kamareth CD, Kishore BK. Effect of aldosterone infustion in a background of high sodium diet in P2Y2 receptor knockout mice. Presented at the 41st Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2008.
  • Listhrop R. Zhang Y, Charlotte H, Kamareth CD, Ecelbarger CM, Kishore BK. Altered expression of renal sodium transporters/channels in P2Y2 reeptor knockout mice fed high or low salt diet. Presented at the 41st Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2008.
  • Kishore BK, Carlson NG, Nelson RD, Kohan DE. Renal purinergic system - a potent drug target for the treatment of lithium-induced diabetes insipidus. Presented at the Purines 2008 meeting, Copenhagen, Denmark. , , 2008.
  • Zhang Y, Kohan DE, Nelson RD, Kishore BK. Delayed onset or renal escape from vasopressin-induced antidiuresis in mice lacking P2y2 receptor. Presented at the 40th Annual Meeting of the American Society of Nephrology, Sand Francisco, CA. , , 2007.
  • Kishore BK, Kohan DE, Nelson RD, Zhang Y. Effect of water deprivation and water loading on urine parameters in P2Y2 receptor knockout mice. Pestened at the 40th Annual Meeting of the American Society of Nephrology, San Francisco, CA. , , 2007.
  • Klein JD, Sands JM, Martin CF, Zhag Y, Kohan DE, Kishore BK. Chronic and acute effects of vasopressin on AQP2 and UT-A1 protein abundances in the kidneys of mice deficient in P2Y2 receptor. Presented at the 40th Annual Meeting of the American Society of Nephrology, San Francisco, CA. , , 2007.
  • Kishore BK, Judge JP, Sun R, Nelson RD, Kohan DE. Manifestation of renal phenotype in mice with genetic deltion of P2Y2 receptor. Presented at the 39th Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2006.
  • Judge JP, Kohan DE, Carlson NG, Nelson RD, Kishore BK. Mice with genetic deletion of P2Y2 receptor are markedly reistant to lithium-induced polyuria. Presented at the 39th Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2006.
  • Kohan DE< Kishore BK, Stricklett PK, Hughes AK. Adenosine triphosphate via the P2Y2 receptor inhibits endothelin-1 release from inner medullary collecting duct. Presented at the 38th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2005.
  • Sun R, Miller RL, Zhang P, Kishore BK, Nelson RD. dDAVP, but not the hypertonicity of the medium, decreases the expression of P2Y2 receptor mRNA in primary cultures of mouse inner medullary collecting duct cells. Presented at the 38th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2005.
  • Kishore BK, Kohan DE, Carlson NG, Nelson RD, Sun R. Apyrase treatment reverses the autmented P2Y2 receptor-mediated PGE2 production by inner medullary collecting duct in rats with lithium-induced nephrogenic diabetes insipidus. Presented at the 38th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2005.
  • Mauch TJ, Phan HX, Shi H, Krane CM, Kishore BK. Developmental expression of P2Y2 receptor protein and mRNA in embryonic and newborn mouse kidney. Presented at the 38th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2005.
  • Krane CM, Phan HX, Mauch TJ and Kishore BK. Developmental expression pattern of P2Y2 receptor protein in the endoderm-derived organs (GI tract and pulmonary system) of embryonic mouse. Abstract presented at the EB2005/IUPS Meeting, San Diego, CA. , , 2005.
  • Sun R, Carlson NG, Shi H, Hemmert AC and Kishore BK. Hydration of rats markedly enhances purinergic-mediated PGE2 release from medullary collecting ducts (mCD) in a time-, concentration- and cyclooxygenase -1-dependent manner. Abstract presented at the EB2005/IUPS Meeting, San Diego, CA. , , 2005.
  • Kishore BK, Isaac J, Shi H and Westenfelder C. Persistent expression of erythropoietin (EPO) mRNA and protein by proliferating peritubular cells in the kidneys of rats treated with poly-D-glutamic acid: Possible phenotypic transformation and utility for the study of EPO biology. Abstract presented at the EB2005/IUPS Meeting, San Diego, CA. , , 2005.
  • Mauch TJ, Phan HX, Krane CM and Kishore BK. Developmental expression pattern of P2Y2 receptor protein in mesoderm-derived organs (heart, kidney and adrenals) in fetal mouse. Abstract presented at the EB2005/IUPS Meeting, San Diego, CA. , , 2005.
  • Sun R, Nelson RD, Carlson NG, Miller RL, Shi H, Zhang P, Hemmert AC, Kohan DE and Kishore BK. Enhanced purinergic-mediated PGE2 release from the medullary collecting duct of rats with acquired nephrogenic diabetes insipidus: Pathophysiological and therapeutic implications. Abstract presented at the EB2005/IUPS Meeting, San Diego, CA. , , 2005.
  • Sun R, Carlson NG, Shi H, Hemmert A and Kishore BK. Inner medullary collecting ducts (IMCD) from hydrated and dehydrated rat kidneys show altered response to P2Y2 receptor-stimulated prostaglandin E2 release: Implications for vasopressin-independent regulation of IMCD function. Abstract presented at the 37th Annual Meeting of the American Society of Nephrology, St. Louis, MO. , , 2004.
  • Miller RL, Ecelbarger CA, Hemmert A, Zhang P, Shi H, Nelson RD and Kishore BK. Cisplatin-treatment causes decreased mRNA expression of aquaporins-1, 2 and 7 and vasopressin V2 receptor in rat kidneys: A real-time RT-PCR approach. Abstract presentated at the 37th Annual Meeting of the American Society of Nephrology, St. Louis, MO. , , 2004.
  • Kishore BK, Miller RL, Shi H, Zhang P and Nelson RD. Chronic dDAVP infusion in rats causes decreased expression of P2Y2 receptor mRNA and protein in inner medulla. Abstract presented at the 37th Annual Meeting of the American Society of Nephrology, St. Louis, MO. , , 2004.
  • Kishore BK, Nelson RD. Purinergic control of medullary collecting duct function: A novel vasopressin-independent regulatory mechanism. Presented at the 2004 NDI Global Conference, Phoenix, AZ. , , 2004.
  • Kishore BK, Isaac J, Tripp SR, Shi H, Hemmert A, and Bollen M. Cellular localization of nucleotide pyrophosphatase/phosphodiesterases (NPPs) in rat kidney. Presented at the Experimental Biology 2004, Washington, DC. , , 2004.
  • Kishore BK, Isaac H, Tripp S, Shi H, Baranowski RL and Westenfelder C. A novel method of induction of proliferation of erythropoietin-producing peritubular cells in rat kidney. Presented at the 36th Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 2003.
  • Welch BD, Carlson NG, Shi H and Kishore BK. Purinergic stimulated release of prostaglandin E2 in rat inner medullary collecting duct preparations. Presented at the Experimental Biology 2003, San Diego, CA. , , 2003.
  • Sheikh-Hamad D, Cacini W, Buckley AR, Isaac J and Kishore BK. Cellular and molecular characterization of cisplatin-induced cell necrosis and apoptosis in rat kidney. Experimental Biology 2003, San Diego, CA. , , 2003.
  • Kishore BK, Isaac J, Sevigny J and Robson SC. Localization of CD39L1/vascular NTP diphosphohydrolase in murine kidney. 35th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2002.
  • Kishore BK, Isaac J, Tripp SR, Sevigny J and Robson SC. Localization of CD39/vascular NTP diphosphohydrolase in rat kidney. 35th Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 2002.
  • Kishore BK, Isaac J, Tripp SR, Sevigny H and Robson SC. Immunolocalization of vascular NTP diphosphoydrolases (NTPDases) in murine kidney. Third International Workshop on Ecto-ATPases and Related Ectonucleotidases (Metabolism of Extracellular Nucleotides: Secretion, hydrolysis, signaling), Marine Biological Laboratory, Woods Hole, MA. , , 2002.
  • Kishore BK, Trip SR, Cacini W and Isaac J. Renal vascular endothelial growth factor expression during cisplatin-induced ARF in rats. ASN/ISN World Congress of Nephrology, San Francisco, CA. , , 2001.
  • Ecelbarger CA, Cacini W, Bickel C and Kishore BK. Regulation of the abundance of renal thick ascending limb salt transporters during cisplatinum-induced polyuria. 33rd Annual Meeting of the American Society of Nephrology, Toronto, Canada. , , 2000.
  • Kishore BK, DiIulio D, Menon AG and Krane CM. Altered abundance and subcellular distribution of P2Y2-purinoceptor protein in inner medulla of thirsted and hydrated rats: Possbible basis for vasopressin-independent regulation of water transport. 33rd Annual Meeting of the American Society of Nephrology, Toronto, Canada. , , 2000.
  • Kishore BK, Myatt L, Brockman D and Sahay R. Differential subcellular localization of cytosolic phospholipase A2 in inner medulla of dehydrated and hydrated rats. 33rd Annual Meeting of the American Society of Nephrology, Toronto, Canada. , , 2000.
  • Kishore BK, Cacini W, DiIulio D, Rouillard P, Doran JJ and Sands JM. Cisplatin-induced reversal of urea concentration gradient in rat kidney is not associated with significant changes in urea transporter abundance. 33rd Annual Meeting of the American Society of Nephrology, Toronto, Canada. , , 2000.
  • Kishore BK, DiIulio D, Menon AG and Krane CM. Expression of P2Y2-purinoceptor mRNA in renal medulla of thirsted and hydrated rats: Possible basis for AVP-independent regulation of water transport. Experimental Biology 2000 meeting, San Diego, CA. , , 2000.
  • Kishore BK, LeBrun M, Umanath K, DiIulio D, Krane CM and Beauchamp D. Dysregulation of apical Na-K-2Cl cotransporter (BSC1) and AQP3 in renal medulla of rats treated with low doses of gentamicin (GM). Experimental Biology 2000 meeting, San Diego, CA. , , 2000.
  • Kishore BK, Wang Z, Rabb H, Haq M and Soleimani M. Upregulation of P2Y2-purinoceptor during ischemic reperfusion injury (IRI): Possible relevance to diuresis of IRI. 31st Annual Meeting of the American Society of Nephrology, Philadephia, PA. , , 1998.
  • Kishore BK, Ginns SN, Nielsen S and Knepper MA. Localization of P2Y2 -purinoceptor in rat inner medulla. 31st Annual Meeting of the American Society of Nephrology, Philadelphia, PA. , , 1998.
  • Kishore BK, Schorr K, Mandon B, Wade JB and Knepper MA. Synaptotogamin-8 localization in rat kidney. 30th Annual Meeting of the American Society of Nephrology, San Antonio, TX. , , 1997.
  • Kishore BK, Mandon B, Nielsen S and Knepper MA. Tagmin-6 is expressed in the collecting duct principal cells: A possible molecular switch in vasopressin-induced water channel trafficking. 29th Annual Meeting of the American Society of Nephrology, New Orleans, LA. , , 1996.
  • Kishore BK, Terris J and Knepper MA. Ultramicro-determination of vasopressin-regulated urea transporter protein in microdissected tubule segments: effect of low-protein diet. 29th Annual Meeting of the American Socity of Nephrology, New Orleans, LA. , , 1996.
  • Kishore BK, Terris JM and Knepper MA. Quantification of aquaporin 2 water protein in microdissected rat renal tubule segments. 28th Annual Meeting of the American Society of Nephology, San Diego, CA. , , 1995.
  • Kishore BK, Mandon B, Oza NB, DiGiovanni SR, Coleman RA, Wade JB and Knepper MA. The rat renal arcade segment is a site of expression of the V2 vasopressin receptor and the vasopressin regulated water channel. 28th Annual Meeting of the American Society of Nephrology, San Diego, CA. , , 1995.
  • Kishore BK and Knepper MA. Extracellular nucleotide receptor mediates inhibition of AVP stimulated osmotic water permeability in terminal inner medullary collecting duct. 27th Annual Meeting of the American Society of Nephrology, Orlando, FL. , , 1994.
  • Kishore BK, Scorneaux B, Ibrahim S and Tulkens PM. Uptake and subcellular distribution of poly L aspartic acid, a protectant against aminoglycoside induced nephrotoxicity, and poly L glutamic acid in rat kidney cortex. 33rd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), New Orleans, LA. , , 1993.
  • Lu Fuming, Kishore BK and Tulkens PM: Pharmacokinetics and renal uptake of poly L aspartic and poly L glutamic acids in rats. 32nd Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Anaheim, CA. , , 1992.
  • Kishore BK, Maldague P, Hauvax X, Ibrahim S, Tulkens PM and Courtoy PJ: Cytochemical and physicochemical characterization of the acute thesaurismosis induced by poly D glutamic acid in rat kidney cortex. 5th International Congress on Cell Biology, Madrid (Spain). , , 1992.
  • Montenez JP, Delaisse JM, Vaes G, Tulkens PM and Kishore BK: Increased activities of cathepsin B and other lysosomal hydrolases in fibroblasts and bone tissue cultured in the presence of leupeptin. 5th International Congress on Cell Biology, Madrid (Spain). , , 1992.
  • Piret J, Kishore BK and Tulkens PM. Effect of delipidation of rat liver lysosomal phospholipase A1 on its activity towards phosphatidylcholine included in liposomes and on its inhibition by gentamicin. American Society for Biochemistry and Molecular Biology Fall Symposium, "Biological Significance of Lipid Modification of Proteinsm," Keystone, CO. , , 1991.
  • Kishore BK, Montenez JP, Maldague P and Tulkens PM. E 64, an inhibitor of cystein proteinases prevents gentamicin induced lysosomal phospholipidosis and myeloid bodies formation in cultured fibroblasts. 31st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL. , , 1991.
  • Maldague P, Kishore BK, Van Schepdael A, Lambricht P, Laurent G, Claes PJ and Tulkens PM. Morphological lesions induced by Co oxydextran, administered alone or in combination with gentamicin, in the renal cortex of rats. Seventh International Symposium of Nephrology at Montecatini, "Kidney, Proteins and Drugs," Montecatini Terme, Italy. , , 1991.
  • Kishore BK, Ibrahim S, Lambricht P, Laurent G, Maldague P and Tulkens PM. Influence of co administration of poly L aspartic acid on the gentamicin induced rena lysosomal phospholipidosis, qualitative and quantitative lysosomal alterations and cell turn over in rat kidney cortex. The Symposium on Acute Renal Failure: "Factors Affecting Severity of Injury and Recovery of Function," Chapel Hill, NC. , , 1991.
  • Kishore BK, Ibrahim S, Lambricht P, Laurent G, Maldague P and Tulkens PM. Comparative evaluation of the effects of co administration of poly L aspartic and poly L glutamic acids on the qualitative and quantitative alterations of lysosomes and cell turn over induced by gentamicin in rat kidney cortex. 31st Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Chicago, IL. , , 1991.
  • Kishore BK, Maldague P, Laurent G, Lambricht P, Ibrahim S and Tulkens PM. Acute lysosomal thesaurismosis of proximal tubular cells and proliferation of peritubular cells induced by poly D glutamic acid in rat kidney cortex. The Symposium on Acute Renal Failure: "Factors Affecting Severity of Injury and Recovery of Function," Chapel Hill, NC. , , 1991.
  • Kishore BK, Van Schepdael A, Laurent G, Lambricht P, Piret J, Claes PJ, Maldague P and Tulkens PM. Effect of Co oxydextran on the early renal alterations induced by gentamicin in rats. Seventh International Symposium of Nephrology at Montecatini, "Kidney, Proteins and Drugs," Montecatini Terme, Italy. , , 1991.
  • Kishore BK, Ibrahim S, Lambricht P, Wagner R, Gerard F, Maldague P and Tulkens PM. Leupeptin (an inhibitor of cathepsin B), as protectant against gentamicin induced lysosomal phospholipidosis: Prospectives and limitations. The EUROTOX Congress, Maastricht, The Netherlands. , , 1991.
  • Kishore BK and Tulkens PM. Evaluation of polyanions and protease inhibitors as modulators of early aminoglycoside(AG) induced toxicity (lysosomal phospholipidosis; LPL) in a model of cultured fibroblasts. 17th International Congress of Chemotherapy, Berlin (West). , , 1991.
  • Kishore BK, Maldague P, Laurent G and Tulkens PM. Acute lysosomal thesaurismosis of proximal tubular cells induced by poly D glutamic acid in rat kidney cortex. Eighth ESGLD (European Study Group on Lysosomal Diseases) Workshop, Annecy, France. , , 1991.
  • Kishore BK. Nephrotoxicity of aminoglycoside antibiotics: Biology, clinical implications and development of protective mechanisms. In: Topics in Intensive Care, Proceedings of the Dutch Society of Intensive Care (NVIC), Amsterdam, The Netherlands. , , 1991.
  • Tulkens PM and Kishore BK. Macrophage and fibroblast cultures for assessment of activity and modulation of toxicity of antimicrobials. Symposium on Cell Culture Models at the 30th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Atlanta, GA. , , 1990.
  • Kishore BK, Piret J, Lambricht P and Tulkens PM. Leupeptin (LP; an inhibitor of Cathepsin B) prevents gentamicin induced lysosomal phospholipidosis (LPL) in cultured fibroblasts and aids poly L glutamic acid to become a protectant against LPL. 30th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Atlanta, GA, USA. , , 1990.
  • Kishore BK, Ibrahim S, Lambricht P, Laurent G, Maldague P and Tulkens PM. In vitro and in vivo evaluation of poly L aspartic and poly L glutamic acids as protectants against aminoglycoside induced nephrotoxicity: Further evidence for a lysosomal site of action. 29th Interscience Conference on Antimicrobial Agents and Chemotherapy, ICAAC, Houston, TX. , , 1989.
  • Kishore BK, Lambricht P, Laurent G and Tulkens PM. In vitro studies on anionic polypeptides as protectants against aminoglycoside induced nephrotoxicity. Fifth International Congress of Toxicolgy, IUTOX'89, Brighton, UK. , , 1989.
  • Maldague P, Kishore BK, Lambricht P, Laurent G and Tulkens PM. Inhibition of aminoglycoside induced nephrotoxicity in rats by polyanionic peptides II: Morphological studies. Sixth International Symposium of Nephrology: Kidney, Proteins and Drugs, Montecatini (Pisa), Italy. , , 1989.
  • Kishore BK, Lambricht P, Ibrahim S, Laurent G and Tulkens PM. Inhibition of aminoglycoside induced nephrotoxicity in rats by polyanionic peptides I: in vitro and in vivo biochemical studies. Sixth International Symposium of Nephrology: Kidney, Proteins and Drugs, Montecatini (Pisa), Italy. , , 1989.
  • Kishore BK, Mingeot Leclercq MP, Kallay Z, Beauchamp D and Tulkens PM. Mechanism of the protection afforded by poly L aspartic acid (pASP) against gentamicin(GM) induced nephrotoxicity: pASP binds GM in lysosomes. 28th Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC), Los Angeles, CA. , , 1988.
  • Kishore BK, and Tulkens PM.Comparative assessment of poly L aspartic and poly L glutamic acids as protectants against aminoglycoside-induced nephrotoxicity. 29th Congress of the European Society of Toxicology and the 3rd Congress of the Federation of the European Societies of Toxicology, (EUROTOX'88), Munchen, Germany. , , 1988.
  • Kishore BK, Ibrahim S and Tulkens PM. Increased levels of protein and lipid bound sialic acids in the renal cortex of rats injected with low doses of aminoglycoside antibiotics. 14th International Congress of Biochemistry, Prague, Czechoslovakia. , , 1988.
  • Kishore BK, Kallay Z and Tulkens PM. Poly L aspartic acid, a protectant against aminoglycoside induced nephrotoxicity, binds gentamicin in vitro: Possible relevance to in vivo protectant action. 8th International Symposium on Future Trends in Chemotherapy, Tirrenia (Pisa), Italy. , , 1988.
  • Gejyo F, Baba S, Watanabe Y, Kishore BK and Arakawa M. Possibility of a common metabolic pathway for the production of methylguanidine and dimethylamine in chronic renal failure. International Symposium on Guanidino Compound, Tokyo, Japan. , , 1983.
  • Kishore BK, Gejyo F and Arakawa M. Changes in the glycosylation and sialylation of serum proteins and lipid bound sialic acids in chronic renal failure. 25th Congress of the Japanese Society of Nephrology, Tokyo, Japan. , , 1982.

Languages

  • English, Fluent.
  • Telugu, Fluent.
  • Hindi, Fluent.
  • French, Basic.

Publications

  • Peti-Peterdi J, Kishore BK, Pluznick JL (date unknown). Regulation of Vascular and Renal Function by Metabolite Receptors. (pp. 391-414). Vol. 78. Accepted, .
  • Kishore BK, Maldague P, Laurent G, Mingeot-Leclercq MP, Ibrahim S, Tulkens PM (date unknown). Acute renal failure induced by aminoglycoside antibiotics: Pathophysiology, clinical implications and development of protective measures. (pp. 401-409). Oxford University Press. Accepted, .
  • Zhang Y, Peti-Peterdi J, Heiney KM, Riquier-Brison A, Carlson NG, Muller CE, Ecelbarger CM, Kishore BK (date unknown). Clopidogrel attenuates lithium-induced alterations in renal water and sodium channels/transporters in mice. Vol. 11, 507-18. Accepted, .
  • Zhang Y, Li L, Kohan DE, Ecelbarger CM, Kishore BK. (date unknown). Attenuation of lithium-induced natriuresis and kaliuresis in P2Y2 receptor knockout mice. Vol. 305, F407-F416. Accepted, .
  • Kishore BK, Zhang Y, Geovrgyan H, Kohan DE, Schiedel AC, Muller CE, Peti-Peterdi J (date unknown). Cellular localization of adenine receptors (AdeR) in the rat kidney, and their functional significance in the inner medullary collecting duct. Vol. Aug 28, 1-8. Accepted, .
  • Zhang Y, Pop IL, Carlson NG, Kishore BK (date unknown). Genetic deletion of P2Y2 receptor offers significant resistance for the development of lithium-induced polyuria accompanied with alterations in PGE2 signaling. Vol. 302, F70-F77. Accepted, .
  • Zhang Y, Morris KM, Sparrow SK, Dwyer KM, Enjyoji K, Robson SC, Kishore BK (date unknown). Defective renal water handling in transgenic mice over-exprssing human CD39/NTPDase1. Vol. 303, F420-F430. Accepted, .
  • Zhang Y, Listhrop R, Ecelbarger CM, Kishore BK. (date unknown). Renal sodium transporter/channel expression and sodium excretion in P2Y2 receptor knockout mice fed high NaCl diet with/without aldosterone infusion. Vol. 300, F657-F668. Accepted, .
  • Zhang Y, Kohan DE< Nelson RD, Carlson NG, Kishore BK (date unknown). Potential involvement of P2Y2 receptor in diuresis of post-obstructive uropathy in rats. Vol. 298, F634-F642. Accepted, .
  • Zhang Y, Nelson RD, Carlson NG, Kamerath CD, Kohan DE, Kishore BK (date unknown). Potential role of purinergic signaling in lithium-induced nephrogenic diabetes insipidus. Vol. 296, F1194-1201. Accepted, .
  • Zhang Y, Sands JM, Kohan DE, Nelson RD, Martin CF, Carlson NG, Kamerath CD, Ge Y, Kelin JD, Kishore BK (date unknown). Potential role of purinergic signaling in urinary concentration in inner medulla: Insights from P2Y2 gene knockout mice. Vol. 295, F1715-F1724. Accepted, .
  • Zhang Y, Peti-Peterdi J, Brandes AU, Riquier-Brison A, Carlson NG, Muller CE, Ecelbarger CM, Kishore BK (date unknown). Prasugrel suppresses development of lithium-induced nephrogenic diabetes insipidus in mice. Vol. 13, 239-248. Accepted, .
  • Kishore BK, Isaac J, Fausther M, Tripp SR, Shi H, Gill PS, Braun N, Zimmermann H, Sevigny J, Robson SC (date unknown). Expression of NTPDase1 and NTPDase2 in murine kidney: relevance to regulation of P2 receptor signaling. Vol. 288, F1032-43. Accepted, .
  • Kishore BK, Carlson NG, Ecelbarger CM, Kohan DE, Müller CE, Nelson RD, Peti-Pterdi J, Zhang Y (date unknown). Targeting renal purinergic signalling for the treatment of lithium-induced nephrogenic diabetes insipidus. Vol. 214, 176-188. Accepted, .
  • Thimm D, Schiedel AC, Peti-Peterdi J, Kishore BK, Müller CE (date unknown). The nucleobase adenine as a signalling molecule in the kidney. Vol. 213, 808-818. Accepted, .
  • Kishore BK, Ecelbareger CM (date unknown). Lithium: A versatile tool for understanding renal physiology. (pp. F1139-F1149). Vol. 304. Accepted, .
  • Kishore BK, Nelson RD, Miller RL, Carlson NG, Kohan DE. (date unknown). P2Y2 receptor and water transport in the kidney. (pp. 491-499). Vol. 5. Accepted, .
  • Krane CM, Kishore BK (date unknown). Aquaporins: Membrane water channels of the biological world. (pp. 81-86). Vol. 50. Accepted, .
  • Mingeot-Leclercq MP, Laurent G, Kishore BK, Tulkens PM (date unknown). Aminoglycoside Nephrotoxicity. (pp. 113-141). Vol. 10. Accepted, .