CAROL LIM portrait
  • Member, Huntsman Cancer Institute
  • Biological Chemistry Faculty, Pharmaceutical Chemistry
  • Adjunct Professor, Pharmacology And Toxicology
  • Professor, Pharmaceutical Chemistry

Research Keywords

  • Gene Therapy
  • Peptides
  • Cancer Therapeutic Development
  • Tumor Suppressor Proteins
  • DNA/Gene Targeted Therapeutics
  • Gene Expression Regulation
  • Cellular Kinetics
  • Nuclear Import and Export
  • Ovarian Cancer
  • Chronic Myeloid Leukemia
  • Mitochondrial Signaling

Presentations

  • Department of Pharmaceutical Sciences at the University of Nebraska Medical Center, “Peptide and Gene Therapy for Cancer Using Re-engineered Protein Domains”. , , 2015.
  • University of Pittsburg, School of Pharmacy, Department of Pharmaceutical Sciences Seminar Series, Invited Speaker. "Re-Engineering Protein Domains for Cancer Therapy". , , 2013.
  • University of Pennsylvania, Perlman School of Medicine, Dept. of Pharmacology, Invited Speaker. "Subcellular Targeting of Biotherapeutics: Location Alters Function". , , 2013.
  • Biological Chemistry Recruiting Weekend, "Coiled Coils as Therapeutic Targets". , , 2013.
  • Departmental Lab Chat: Effectively Using Your Committee (C. Lim and W. Sanders). , , 2012.
  • University of Maryland, Baltimore, Department of Pharmaceutical Sciences, "Targeting Nodal Proteins for Cancer Therapy". , , 2011.
  • Departmental Lab Chat: Scientific Writing (D. Woessner, C. Lim, and D. Grainger). , , 2010.
  • Departmental Seminar: Teaching Excellence Seminar (M. Mossalam, C. Lim, and D. Zigenfuss). , , 2010.
  • University of Kansas (Lawrence), Department of Pharmaceutics, “Location Alters Function: Making the Switch to Apoptosis”. , , 2010.
  • Apoptosis and Cancer: A Mini-Symposium, sponsored by the Huntsman Cancer Institute Cell Response and Regulation Program, “Controlling Subcellular Localization to Alter Function: Making the Switch to Apoptosis”. , , 2009.
  • SUNY Buffalo, Department of Pharmaceutical Sciences, “Controlling Subcellular Localization to Alter Function: Making the Switch to Apoptosis". , , 2009.
  • University of Wisconsin, Madison, Pharmaceutical Sciences. “Steroid Receptors and Beyond: Harnessing Signal Sequences for Compartmentalization of Proteins”. , , 2005.
  • Virginia Commonwealth University, Pharmaceutical Sciences. “Steroid Receptors and Beyond: Harnessing Signal Sequences for Drug Delivery". , , 2005.
  • Pharmacology and Toxicology Department Seminar Series, Guest Speaker, Univ. of Utah. "Progesterone Receptor: Trafficking, Kinetics, and Molecular Mechanism of Action.". , , 2001.
  • Invited Speaker, Molecular Biology Seminar Series, Brigham Young University, Provo, UT. "Hormone receptor trafficking in living cells.". , , 2000.
  • AAPS Rocky Mountain Regional Meeting, Invited Speaker. "Oncogenes and Tumor Suppressors: From Basic Science to Translation". , , 2013.
  • The L.S. Skaggs Biomedical Research Symposium, University of Colorado, Aurora, CO. Selected speaker from our department. "A Biomolecular Multi-Hit Strategy Targeted Against Bcr-Abl". , , 2012.
  • Biological Chemistry Recruiting Weekend, University of Utah. "Controlling Subcellular Localization to Alter Function: Use of the Protein Switch for Cancer Therapy". , , 2009.
  • 14th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT. “Controlling Subcellular Localization to Alter Function: Use of the ‘Protein Switch’ for Cancer Therapy”. , , 2009.
  • Controlled Release Society 34th Annual Meeting, Long Beach, CA. “Controlled Cellular Delivery of Bcr-Abl Coiled-Coil Domain for Apoptosis of Chronic Myelogenous Leukemia Cells”. , , 2007.
  • From DNA to Chromatin to Cell Biology--A Symposium sponsored by the Laboratory of Receptor Biology and Gene Expression, CCR, NCI, National Institutes of Health. "Drug-Receptor Trafficking: Import Kinetics and Export Mechanisms.". , , 2002.
  • Enz Award (Pharmacia), Skokie, Illinois. "The Role of Nuclear Export in the Differential Localization and Trafficking of the Progesterone Receptor Isoforms.". , , 2002.
  • Center for Biopolymers at Interfaces, Colloquium Speaker, Salt Lake City, UT. "Steroid hormone receptor trafficking in living cells.". , , 2000.
  • Biological Chemistry Faculty Research Interest Seminar Series, Univ. of Utah, Salt Lake City, UT. "Subcellular Trafficking and Localization of the Human Progesterone Receptor". , , 2000.
  • Chromatin Interest Group, NIH, Bethesda, MD. "Differential localization and activity of the A and B forms of the human progesterone receptor using green fluorescent protein chimeras.". , , 1998.
  • Laboratory of Receptor Biology and Gene Expression Seminar, NIH, Bethesda, MD. "Differential localization and activity of the A and B forms of the human progesterone receptor using green fluorescent protein chimeras.". , , 1998.
  • Bruno BJ and Lim CS. Inhibition of Bcr-Abl with a Coiled-Coil Protein Delivered by a Leukemia-Specific Cell-Penetrating Peptide. Poster session presented at Recent Advances in Drug Delivery Systems, Salt Lake City, UT. Poster, Presented, 2015.
  • Bruno BJ and Lim CS. Inhibition of Bcr-Abl with a Coiled-Coil Protein Delivered by a Leukemia-Specific Cell-Penetrating Peptide. Poster session presented at American Association for Cancer Research Annual Meeting, Philadelphia, PA. Poster, Presented, 2015.
  • Miller, GD and Lim, CS. Therapeutic Use of a Mutant Coiled-Coil Peptide for BCR-ABL Inhibition. Poster session presented at St. Jude Children’s Research Hospital National Graduate Student Symposium, Memphis, TN. Poster, Presented, 2014.
  • Okal A, Mossalam M, Matissek KJ, and Lim CS. Bypassing the Dominant-Negative Effect of Mutant p53 in Breast Cancer Cells. Poster session presented at Bioscience Symposium, Salt Lake City. Poster, Presented, 2013.
  • Okal A, Mossalam M, Matissek KJ, and Lim CS. Bypassing the Dominant-Negative Effect of Mutant p53 in Cancer Cells. Poster session presented at American Association for Pharmaceutical Scientists Regional Meeting: Perspectives in Translational and Clinical Research, Salt Lake City, UT. Poster, Presented, 2013.
  • Matissek KJ, Mossalam M, Okal A, and Lim CS. Targeting Small Domains of p53 to Mitochondrial Bcl-XL for Cancer Therapy. Poster session presented at American Association for Pharmaceutical Scientists Rocky Mountain Discussion Group: Perspectives in Translational and Clinical Research, Salt Lake City, UT. Poster, Presented, 2013.
  • Miller GD, Woessner DW, Sirch MJ, and Lim CS. Abstract #2170: Development of a “dual-hit” combination therapy for CML. Poster presented at. Poster session presented at AACR Annual Meeting, Washington, DC. Poster, Presented, 2013.
  • Okal A, Mossalam M, Matissek KJ, and Lim CS. An Alternative Tetramerization Domain of p53 for Exclusive Homo-oligomerization and Potent Tumor Suppression. Poster session presented at American Association for Cancer Research Annual Meeting, Washington, DC. Poster, Presented, 2013.
  • Matissek KJ, Mossalam M, Okal A, and Lim CS. Targeting Small Domains of p53 to Mitochondrial Bcl-XL for Cancer Therapy. Poster session presented at American Association for Cancer Research Annual Meeting, Washington, DC. Poster, Presented, 2013.
  • Okal A and Lim CS. An Alternative Tetramerization Domain of p53 Circumvents Transdominant Inhibition of Mutant p53. Poster session presented at St. Jude National Graduate Student Symposium, Memphis, TN. Poster, Presented, 2013.
  • Matissek KJ, Mossalam M, Okal A, and Lim CS. Targeting Small Domains of p53 to Mitochondrial Bcl-XL for Cancer Therapy. Poster session presented at 16th International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT. Poster, Presented, 2013.
  • Wallace TC, Okal A, and Lim CS. Altering the Tetramerization Domain of p53 for Cancer Gene Therapy. Poster session presented at Undergraduate Research Opportunities Program, Research Posters on the Hill, Salt Lake City, UT. Poster, Presented, 2013.
  • Woessner DW, Dixon AS, Howard K, Miller GD, Gu Z, Eiring AE, Deininger MW, Lim CS.. Synthetically Lethal Combinations for CML Therapy—Disrupting Dimerization of Bcr-Abl and Secondary Leukemia Specific Pathways. Poster session presented at American Association of Pharmaceutical Scientists Annual Meeting and Exposition, Chicago, IL. Poster, Presented, 2012.
  • Matissek KJ, Mossalam M, Okal A., Constance JE, and Lim CS. Targeting p53 to Mitochondrial Outer Memberane Using the Bcl-XL Signal Causes p53-Specific Apoptosis. Poster session presented at Bioscience Symposium, Salt Lake City, UT. Poster, Presented, 2012.
  • Miller GD, Dixon AS, Bruno BJ, Constance JE, Woessner DW and Lim CS. Improved Coiled-Coil Design Enhances Interaction with Bcr-Abl and Induces Apoptosis (Abstract #3852). Poster session presented at AACR Annual Meeting, Chicago, IL. Poster, Presented, 2012.
  • Woessner DW and Lim CS.. Combination therapy for chronic myelogenous leukemia: Targeting the BCR-ABL coiled-coil domain and other pathways for synthetic lethality. Poster session presented at American Association for Cancer Research 103rd Annual Meeting, Chicago, IL. Poster, Presented, 2012.
  • Okal A, Mossalam M, Matissek KJ, and Lim CS. Bypassing the Dominant-Negative Effect of Mutant p53 in Breast Cancer Cells. Poster session presented at American Association for Cancer Research Annual Meeting, Chicago, IL. Poster, Presented, 2012.
  • Matissek KJ, Mossalam M, Okal A, Constance JE, Lim, CS. Targeting p53 to Mitochondrial Outer Memberane Using the Bcl-XL Signal Causes p53-Specific Apoptosis. Poster session presented at American Association for Cancer Research Annual Meeting, Chicago, IL. Poster, Presented, 2012.
  • Matissek KJ, Mossalam M, Okal A, and Lim CS. Direct Induction of Apoptosis Using an Optimal Mitochondrially Targeted p53. Research featured in AAPS Today: "Apoptosis of Cancer Cells Achieved by Targeting Mitochondria?". Poster session presented at American Association of Pharmaceutical Scientists, Washington, DC. Poster, Presented, 2011.
  • Woessner DW, Dixon AS, and Lim CS. A Multiple Pathway Approach for CML. Poster session presented at Combined Research Trainee Symposium/17th Annual University of Utah Frank Tyler Fall Medical Student Research Symposium., Park City, UT. Poster, Presented, 2011.
  • Woessner DW, Dixon AS and Lim CS. Potentiating chronic myeloid leukaemia treatment using oligomeric disruption and RNAi. Poster session presented at American Association for Cancer Research 102nd Annual Meeting, Orlando, FL. Poster, Presented, 2011.
  • ConstanceJE and Lim CS. Activation of a cryptic mitochondrial localization signal in breast cancer and leukemia cells. Poster session presented at Bioscience Symposium, Salt Lake City, UT. Poster, Presented, 2011.
  • ConstanceJE and Lim CS. Engineering a Bcr-Abl activated MTS. Poster session presented at Intermountain Graduate Research Symposium, Logan, Utah. Poster, Presented, 2011.
  • Mossalam M and Lim CS. Simultaneous Targeting of p53 to the Nucleus and Mitochondria for Breast Cancer Therapy. Poster session presented at 5th Biological Therapeutics Research and Development, San Francisco, CA. Poster, Presented, 2010.
  • Dixon AS and Lim CS. A Rationally-Designed Coiled-Coil for Improved Binding and Inhibition of Bcr-Abl. Poster session presented at Intermountain Graduate Research Symposium, Logan, UT. Poster, Presented, 2010.
  • Woessner DW, Dixon AS, Bruno BJ, Cheatham TE, and Lim CS. Pulling CML's Lynchpin. Poster session presented at Combined Research Trainee Symposium/16th Annual Frank Tyler Fall Medical Student Research Symposium, Park City, UT. Poster, Presented, 2010.
  • Woessner DW, Dixon AS and Lim CS. A Multiple Pathway Approach For Treating Chronic Myelogenous Leukemia. Poster session presented at From the RNA World to the Clinic Symposium, HHMI Janelia Farm Research Campus, Ashburn, VA. Poster, Presented, 2010.
  • Mossalam M and Lim CS. Designing a Protein Switch to Control Proteasomal Targeting. Poster session presented at Bioscience Symposium, Salt Lake City, UT. Poster, Presented, 2010.
  • Mossalam M and Lim CS. Controlled Nuclear Localization of p53 in Breast Cancer Cells. Poster session presented at 13th American Society of Gene & Cell Therapy Annual Meeting, Washington, DC. Poster, Presented, 2010.
  • Mossalam M and Lim CS. Optimizing p53 Targeting to the Mitochondria of Breast Cancer Cells. Poster session presented at Intermountain Graduate Research Symposium, Logan, UT. Poster, Presented, 2010.
  • Dixon AS, Bruno BJ, Woessner DW, Shimpi AA, Lim CS. A Designed Coil-Coil for Improved Disruption of Bcr-Abl Oligomerization. Poster session presented at Globalization of Pharmaceutics Education Network., Chapel Hill, NC. Poster, Presented, 2010.
  • Dixon AS, Bruno BJ, Woessner DW, Shimpi AA, Lim CS. A Designed Coil-Coil for Improved Disruption of Bcr-Abl Oligomerization. Poster session presented at American Association of Pharmaceutical Scientists joint meeting with Pharmaceutical Sciences World Congress, New Orleans, LA. Poster, Presented, 2010.
  • Constance JE and Lim CS. Inducing selective chronic myelogenous leukemia (CML) cell death through the toxic consequences of targeting Bcr-Abl into the mitochondria. Poster session presented at Intermountain Graduate Research Symposium, Logan, UT. Poster, Presented, 2010.
  • Constance JE and Lim CS. Mitochondrial targeting of Bcr-Abl is toxic to chronic myelogenous leukemia cells. Poster session presented at 5th Biological Therapeutics Research & Development Conference, San Francisco, CA. Poster, Presented, 2010.
  • Dixon AS, Kakar M, Lim CS. Controlling Bcr-Abl Localization to Induce Apoptosis in Leukemia Cells. Poster session presented at Controlled Release Society Annual Meeting, New York, NY. Poster, Presented, 2009.
  • Kakar M, Davis JR, and Lim CS. Controlled Localization of Proteins in Cells. Poster session presented at Annual Meeting of the Controlled Release Society, Vienna, Austria. Poster, Presented, 2006.
  • Kakar M, Davis JR, and Lim CS. Mudit Kakar, J. Rian Davis, and C. Lim. Steroid Receptors and Beyond -Harnessing Signal Sequences for Drug Delivery, received the Basic Sciences Best Poster Award. Poster session presented at American Pharmacists Association National Meeting, San Francisco, CA. Poster, Presented, 2006.
  • Cadwallader AB, Lim CS, and Rollins DE. Detection of Anabolic-Androgenic Steroids Using a Cell-Based Human Androgen Receptor Assay. Poster session presented at Society of Forensic Toxicologists, Austin, TX. Poster, Presented, 2006.
  • Kakar M, Davis JR, and Lim CS. Localization Controllable Protein Constructs and their Application in Gene Therapy (Kakar was the recipient of the AAPS Indian Scientists Best Poster Award). Poster session presented at AAPS National Meeting, Nashville, TN. Poster, Presented, 2005.
  • Lim CS. Mechanism and Role of Export in the Differential Localization of Progesterone Receptor Isoforms. Poster session presented at AAPS National Meeting, Salt Lake City, UT. Poster, Presented, 2003.
  • Lim CS. Liganded Progesterone Receptor B Isoform in Living Cells: correlation Between Agonist Dose, Rate of Import, and Transcriptional Activity. Poster session presented at AAPS National Meeting, Salt Lake City, UT. Poster, Presented, 2003.
  • Lim CS. The Role of Export in the Differential Localization of the 2 Isoforms of the Progesterone Receptor. Poster session presented at The Endocrine Society National Meeting, San Francisco, CA. Poster, Presented, 2002.
  • Lim CS. Progesterone Receptor B-isoform in Breast Cancer Cells: Correlation of Drug Dose to Receptor Transport Rate. Poster session presented at AAPS National Meeting, Toronto. Poster, Presented, 2002.
  • Lim CS. Differential Localization of the Human Progesterone Receptor: Is a Nuclear Export Signal Involved? Poster session presented at AAPS National Meeting, Denver, CO. Poster, Presented, 2001.
  • Lim CS. Bidirectional On/Off Switch for Controlled Delivery of Gene Therapy Products. Poster session presented at AAPS National Meeting, Baltimore, MD. Poster, Presented, 2001.
  • Lim CS. Steroid Hormone Receptor Trafficking in Living Cells. Poster session presented at AAPS National Meeting, Indianapolis, IN. Poster, Presented, 2000.
  • Lim CS. Green fluorescent protein chimeras reveal differences between the A and B forms of the human progesterone receptor. Poster session presented at Chromatin, Transcription, and DNA Replication, NIH, Bethesda, MD. Poster, Presented, 1999.
  • Lim CS. Subcellular localization of the A- and B- forms of the human progesterone receptor using green fluorescent protein chimeras. Poster session presented at Endo '99 (The Endocrine Society's 81st Annual Meeting), San Diego, CA. Poster, Presented, 1999.
  • Lim CS (2nd Author). PML colocalizes with GRIP1 and functions in glucocorticoid receptor-dependent transcription. Poster session presented at American Society for Cell Biology's 39th Annual Meeting, Washington DC. Poster, Presented, 1999.
  • Lim CS. Green fluorescent protein chimeras reveal differences between the A- and B- forms of the human progesterone receptor. Poster session presented at AAPS National Meeting, San Francisco, CA. Poster, Presented, 1998.
  • Lim CS. Green fluorescent protein-progesterone receptor chimeras. Poster session presented at Co-Activators and Co-Repressors in Gene Expression, NIH, Bethesda, MD. Poster, Presented, 1998.
  • Lim CS. Multimerization of steroid hormone response elements: an artificial array for hormone receptor targeting. Poster session presented at AAPS National Meeting, Boston, MA. Poster, Presented, 1997.

Languages

  • English, Fluent.

Publications

  • Dixon AS, Kakar M, Schneider KM, Constance JE, Paullin BC, Lim CS (date unknown). Controlling subcellular localization to alter function: Sending oncogenic Bcr-Abl to the nucleus causes apoptosis. Vol. 140, 245-9. Accepted, .
  • Davis JR, Mossalam M, Lim CS (date unknown). Utilizing the estrogen receptor ligand-binding domain for controlled protein translocation to the insoluble fraction. Vol. 29, 3455-63. Accepted, .
  • Constance JE, Woessner DW, Matissek KJ, Mossalam M, Lim CS (date unknown). Enhanced and selective killing of chronic myelogenous leukemia cells with an engineered BCR-ABL binding protein and imatinib. Vol. 9, 3318-29. Accepted, .
  • Kakar M, Cadwallader AB, Davis JR, Lim CS (date unknown). Signal sequences for targeting of gene therapy products to subcellular compartments: the role of CRM1 in nucleocytoplasmic shuttling of the protein switch. Vol. 24, 2146-55. Accepted, .
  • Li H, Fidler ML, Lim CS (date unknown). Effect of initial subcellular localization of progesterone receptor on import kinetics and transcriptional activity. Vol. 2, 509-18. Accepted, .
  • Li H, Yan G, Kern SE, Lim CS (date unknown). Correlation among agonist dose, rate of import, and transcriptional activity of liganded progesterone receptor B isoform in living cells. Vol. 20, 1574-80. Accepted, .
  • Okal A, Mossalam M, Matissek KJ, Dixon AS, Moos PJ, Lim CS (date unknown). A chimeric p53 evades mutant p53 transdominant inhibition in cancer cells. Vol. 10, 3922-33. Accepted, .
  • Matissek KJ, Mossalam M, Okal A, Lim CS (date unknown). The DNA binding domain of p53 is sufficient to trigger a potent apoptotic response at the mitochondria. Vol. 10, 3592-602. Accepted, .
  • Okal A, Matissek KJ, Matissek SJ, Price R, Salama ME, Janat-Amsbury MM, Lim CS (date unknown). Re-engineered p53 activates apoptosis in vivo and causes primary tumor regression in a dominant negative breast cancer xenograft model. Vol. 21, 903-12. Accepted, .
  • Lim CS, Hunt CA (date unknown). Sequential staining of short oligonucleotides in polyacrylamide gels with ethidium bromide and methylene blue. Vol. 17, 626, 628. Accepted, .
  • Kanwal C, Mu S, Kern SE, Lim CS (date unknown). Bidirectional on/off switch for controlled targeting of proteins to subcellular compartments. Vol. 98, 379-93. Accepted, .
  • Miller GD, Woessner DW, Sirch MJ, Lim CS (date unknown). Multidomain targeting of Bcr-Abl by disruption of oligomerization and tyrosine kinase inhibition: toward eradication of CML. Vol. 10, 3475-83. Accepted, .
  • Matissek KJ, Okal A, Mossalam M, Lim CS (date unknown). Delivery of a monomeric p53 subdomain with mitochondrial targeting signals from pro-apoptotic Bak or Bax. Vol. 31, 2503-15. Accepted, .
  • Baumann CT, Lim CS, Hager GL (date unknown). Simultaneous visualization of the yellow and green forms of the green fluorescent protein in living cells. Vol. 46, 1073-6. Accepted, .
  • Lu P, Redd Bowman KE, Brown SM, Joklik-Mcleod M, Vander Mause ER, Nguyen HTN, Lim CS (date unknown). p53-Bad: A Novel Tumor Suppressor/Proapoptotic Factor Hybrid Directed to the Mitochondria for Ovarian Cancer Gene Therapy. Vol. 16, 3386-3398. Accepted, .
  • Dixon AS, Pendley SS, Bruno BJ, Woessner DW, Shimpi AA, Cheatham TE 3rd, Lim CS (date unknown). Disruption of Bcr-Abl coiled coil oligomerization by design. Vol. 286, 27751-60. Accepted, .
  • Woessner DW, Eiring AM, Bruno BJ, Zabriskie MS, Reynolds KR, Miller GD, O'Hare T, Deininger MW, Lim CS (date unknown). A coiled-coil mimetic intercepts BCR-ABL1 dimerization in native and kinase-mutant chronic myeloid leukemia. Vol. 29, 1668-75. Accepted, .
  • Constance JE, Despres SD, Nishida A, Lim CS (date unknown). Selective targeting of c-Abl via a cryptic mitochondrial targeting signal activated by cellular redox status in leukemic and breast cancer cells. Vol. 29, 2317-28. Accepted, .
  • Kakar M, Davis JR, Kern SE, Lim CS (date unknown). Optimizing the protein switch: altering nuclear import and export signals, and ligand binding domain. Vol. 120, 220-32. Accepted, .
  • Okal A, Cornillie S, Matissek SJ, Matissek KJ, Cheatham TE 3rd, Lim CS (date unknown). Re-engineered p53 chimera with enhanced homo-oligomerization that maintains tumor suppressor activity. Vol. 11, 2442-52. Accepted, .
  • Dixon AS, Lim CS (date unknown). The nuclear translocation assay for intracellular protein-protein interactions and its application to the Bcr coiled-coil domain. Vol. 49, 519-24. Accepted, .
  • Cadwallader AB, Rollins DE, Lim CS (date unknown). Effect of anabolic-androgenic steroids and glucocorticoids on the kinetics of hAR and hGR nucleocytoplasmic translocation. Vol. 7, 689-98. Accepted, .
  • Lu P, Vander Mause ER, Redd Bowman KE, Brown SM, Ahne L, Lim CS (date unknown). Mitochondrially targeted p53 or DBD subdomain is superior to wild type p53 in ovarian cancer cells even with strong dominant negative mutant p53. Vol. 12, 45. Accepted, .
  • Mossalam M, Matissek KJ, Okal A, Constance JE, Lim CS (date unknown). Direct induction of apoptosis using an optimal mitochondrially targeted p53. Vol. 9, 1449-58. Accepted, .
  • Dixon AS, Miller GD, Bruno BJ, Constance JE, Woessner DW, Fidler TP, Robertson JC, Cheatham TE 3rd, Lim CS (date unknown). Correction to "improved coiled-coil design enhances interaction with bcr-abl and induces apoptosis". Vol. 9, 1535. Accepted, .
  • Bruno BJ, Lim CS (date unknown). Inhibition of bcr-abl in human leukemic cells with a coiled-coil protein delivered by a leukemia-specific cell-penetrating Peptide. Vol. 12, 1412-21. Accepted, .
  • Bowman KR, Kim JH, Lim CS (date unknown). Narrowing the field: cancer-specific promoters for mitochondrially-targeted p53-BH3 fusion gene therapy in ovarian cancer. Vol. 12, 38. Accepted, .
  • Cornillie SP, Bruno BJ, Lim CS, Cheatham TE 3rd (date unknown). Computational Modeling of Stapled Peptides toward a Treatment Strategy for CML and Broader Implications in the Design of Lengthy Peptide Therapeutics. Vol. 122, 3864-3875. Accepted, .
  • Davis JR, Mossalam M, Lim CS (date unknown). Controlled access of p53 to the nucleus regulates its proteasomal degradation by MDM2. Vol. 10, 1340-9. Accepted, .
  • Reaz S, Mossalam M, Okal A, Lim CS (date unknown). A single mutant, A276S of p53, turns the switch to apoptosis. Vol. 10, 1350-9. Accepted, .
  • Dixon AS, Constance JE, Tanaka T, Rabbitts TH, Lim CS (date unknown). Changing the subcellular location of the oncoprotein Bcr-Abl using rationally designed capture motifs. Vol. 29, 1098-109. Accepted, .
  • Baumann CT, Ma H, Wolford R, Reyes JC, Maruvada P, Lim C, Yen PM, Stallcup MR, Hager GL (date unknown). The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome. Vol. 15, 485-500. Accepted, .
  • Lim CS, Baumann CT, Htun H, Xian W, Irie M, Smith CL, Hager GL (date unknown). Differential localization and activity of the A- and B-forms of the human progesterone receptor using green fluorescent protein chimeras. Vol. 13, 366-75. Accepted, .
  • Lim CS, Jabrane-Ferrat N, Fontes JD, Okamoto H, Garovoy MR, Peterlin BM, Hunt CA (date unknown). Sequence-independent inhibition of RNA transcription by DNA dumbbells and other decoys. Vol. 25, 575-81. Accepted, .
  • Woessner DW, Lim CS (date unknown). Disrupting BCR-ABL in combination with secondary leukemia-specific pathways in CML cells leads to enhanced apoptosis and decreased proliferation. Vol. 10, 270-7. Accepted, .
  • Mossalam M, Soto J, Lim CS, Abel ED (date unknown). Solid phase synthesis of mitochondrial triphenylphosphonium-vitamin E metabolite using a lysine linker for reversal of oxidative stress. Vol. 8, e53272. Accepted, .
  • Dixon AS, Miller GD, Bruno BJ, Constance JE, Woessner DW, Fidler TP, Robertson JC, Cheatham TE 3rd, Lim CS (date unknown). Improved coiled-coil design enhances interaction with Bcr-Abl and induces apoptosis. Vol. 9, 187-95. Accepted, .
  • Davis JR, Kakar M, Lim CS (date unknown). Controlling protein compartmentalization to overcome disease. Vol. 24, 17-27. Accepted, .
  • Kakar M, Kanwal C, Davis JR, Li H, Lim CS (date unknown). Geldanamycin, an inhibitor of Hsp90, blocks cytoplasmic retention of progesterone receptors and glucocorticoid receptors via their respective ligand binding domains. Vol. 8, E718-28. Accepted, .
  • Kanwal C, Li H, Lim CS (date unknown). Model system to study classical nuclear export signals. Vol. 4, E18. Accepted, .
  • Lim CS, Hunt CA (date unknown). Synthesis of DNA dumbbells: chemical vs. enzymatic ligation of self-complementary oligonucleotides. Vol. 16, 41-51. Accepted, .
  • Guy RH, Kalia YN, Lim CS, Nonato LB, Turner NG (date unknown). Drug smuggling- creative ways to cross biological barriers. Vol. 32, 42-45. Accepted, .
  • Hager GL, Lim CS, Elbi C, Baumann CT (date unknown). Trafficking of nuclear receptors in living cells. (pp. 249-54). Vol. 74. Accepted, .
  • Bruno BJ, Miller GD, Lim CS (date unknown). Basics and recent advances in peptide and protein drug delivery. (pp. 1443-67). Vol. 4. Accepted, .
  • Constance JE, Lim CS (date unknown). Targeting malignant mitochondria with therapeutic peptides. (pp. 961-79). Vol. 3. Accepted, .
  • Mossalam M, Dixon AS, Lim CS (date unknown). Controlling subcellular delivery to optimize therapeutic effect. (pp. 169-93). Vol. 1. Accepted, .
  • Miller GD, Bruno BJ, Lim CS (date unknown). Resistant mutations in CML and Ph(+)ALL - role of ponatinib. (pp. 243-54). Vol. 8. Accepted, .
  • Baumann CT, Lim CS, Hager GL (date unknown). Intracellular localization and trafficking of steroid receptors. (pp. 119-27). Vol. 31. Accepted, .