GERALD GENE KRUEGER portrait
  • Professor, Dermatology
801-581-6465

Research Keywords

  • Psoriasis

Presentations

  • "Recovery of RNA From the Stratum Corneum to Historically Assess Inflammatory Events of Psoriasis." Annual American Academy of Dermatology Meeting, Orlando, FL. , , 2017.
  • "New Therapies for the Treatment of Psoriasis, Part 1." Presented to the Anchorage Alaska Dermatologists Group, Anchorage, AK. , , 2015.
  • "New Therapies for the Treatment of Psoriasis, Part 2." Presented to the Anchorage Alaska Dermatologists Group, Anchorage, AK. , , 2015.
  • From Challenges to Discoveries: 42 Years of Research and Practice in Academic Dermatology, Yale University, Department of Dermatology. , , 2014.
  • From Challenges to Discoveries in 42 Years of Practice in Academic Dermatology, Medicine College of Wisconsin, Milwaukee, WI. , , 2014.
  • What's New in the Etiology and Treatment of Psoriasis, Alabama Dermatology Society, Sandestin, FL. , , 2014.
  • "Pathogenesis of Psoriasis", National Psoriasis Foundation, Chief Residents' Meeting, Chicago, IL. , , 2012.
  • "Psoriasis and the Burden of Disease: Calling for Worldwide Action", International Federation of Psoriasis Associations (IFPA), Stockholm, Wweden. , , 2012.
  • "Hair Loss", Practical Dermatology for Primary Care Conference, Salt Lake City, UT. , , 2012.
  • "Psoriasis: More Than Skin Deep", Dermatology in Primary & Specialty Medicine, Ogden Surgical-Medical Society, Ogden, UT. , , 2012.
  • "Practical Application of Clinical Insights in Psoriasis Patient Management", Dermatology Nurses Association, Denver, CO. , , 2012.
  • "Psoriasis: More Than Skin Deep--The Emerging Co-Morbidities", Idaho Dermatology Societies, St. Luke's Hospital, Boise, ID. , , 2012.
  • "Risks and Monitoring of 'Biologics' in Psoriasis", Idaho Dermatology Societies, St. Luke's Hospital, Boise, ID. , , 2012.
  • "Psoriasis and Genetics", and Treatment Algorithms for Psoriasis", Brazilian Rheumatology Conference, Porto Allegre. , , 2010.
  • "Beyond Skin Deep" presentation to primary care providers, Portland, Oregon. , , 2010.
  • Grand Rounds at Marshfield Clinic "Psoriasis: Comorbid States." Marshfield, Wisconsin. , , 2010.
  • Maui Dermatology Conference, "Moderate to Severe Psoriasis Patients with Concomitant Inflammatory Bowel Disease." Maui, Hawaii. , , 2010.
  • AAD Psoriasis Symposium - "What's New with Traditional Biologics:TNF Blockers and Agents that Block T-Cell Activation." - Boston. , , 2009.
  • Grand Rounds at New York University. "Psoriasis: Genotype/Phenotype Associations." New York, New York. , , 2009.
  • National Psoriasis Foundations - Chief Residents Meeting. "Basic Science of Psoriasis." Chicago, IL. , , 2009.
  • 7 speeches launching Adalimumab (Humira). Australia. , , 2009.
  • Medical College of Milwaukee. "Psoriasis: From design 2nd pitfalls of clinical trials to new genes and treatments. Psoriasis 2009- An update." Milwaukee. , , 2009.
  • International Federation of Psoriasis Associations GRAPPA Meeting. Stockholm, Sweden. , , 2009.
  • Research Medical Liason Representatives (Amgen Pharmaceuticals), "Psoriasis Reivew Course". Salt lake City, UT. , , 2008.
  • GRAPPA Meeting, "Screening and assessment in psoriasis and psoriatic arthritis." San Antonio, TX. , , 2008.
  • Psoriasis: From Gene to Clnic Conference - "Understanding Psoriasis by Genotype/Phenotype Associations. London, UK. , , 2008.
  • Hot Topics Symposium, "Overview of Key Immunological events in psoriasis and how this knowledge is translated into current and future treatments and interventions." Copenhagen, Denmark. , , 2008.
  • American Academy of Dermatology Chaired Symposium, "Improving Psoriasis Treatment Outcomes: Managing Comorbid Conditions." Chicago, IL. , , 2008.
  • Dermatology Foundation Clinical Symposium, "Biological Treatment of Autoimmune Diseases" - "Hot Topics". Amelia Island, FL. , , 2008.
  • Valley of the Sun Meeting, "Biologics for skin disease other than psoriasis." Phoenix, AZ. , , 2007.
  • Dermatology Foundation Clinical Symposia. "Hot Topic". Amelia Island, Florida. , , 2007.
  • Winter Skin Seminary:Squaw Valley. "Update on Psoriasis." Squaw Valley, CA. , , 2007.
  • AAD MTG. "Biologics Beyond Psoriasis and Psoriasis Today". Washington D.C. , , 2007.
  • Academy of Dermatology - Osteopathy, "New Treatments for Psoriasis." Santa Fe, NM. , , 2007.
  • John Hopkins University, Immumomodulatory Therapies for Skin Disease: Psoriasis as the Prototype. , , 2002.
  • University of Colorado, "New Era Immunomodulatory therapies, Ps and PsA as the prototype. , , 2002.
  • New York University, "Use of genetically defined skin to treat skin disease; Focus: genetically modified fibroblasts. , , 2001.
  • Loma Linda University, "Considerations in and an Ppdate of Treatment of Psoriasis". , , 2001.
  • University of Southern California, "Considerations in and an update of treatment for psoriasis". , , 2001.
  • University of Colorado, An update on the pathogenesis and therapeutic considerations in the treatment of psoriasis. , , 2000.
  • UCLA (2 lectures dinner meetings) "New Treatment Options for Psoriasis", formal ground tounds Psoriasis - How Advances in Understanding are Leading to New Treatments. , , 2000.
  • Case Western Reserve Dept of Dermatology, review of Center Grant. , , 1998.
  • Stanford University Dept of Dermatology, 1. "Treatment of Psoriasis, Pathogenesis of Psoriasis, current concept", 2. "Cutaneous Pain Syndromes". , , 1997.
  • Mount Sinai College of Medicine, Dept of Dermatology, "cutaneous Pain Syndromes", and Immunopathogenesis of psoriasis". , , 1997.
  • University of Illinois Dept of Biochemistry, "the Challenge of Gene therapy Using Cells of the Skin". , , 1997.
  • Mount Sinai college of Medicine "Treatment of Psoriasis; Pathogenesis of Psoriasis, Current Concepts". , , 1992.
  • Emory University / Atlantic Dermatology Assoc - Quarterly Mtg, Harold Melter Lectureship; 1. Psoriasis RX, 2. BMT TX, 3. Topical Pharmacology. , , 1992.
  • University of Texas Southwestern - "Immunology of psoriasis and topic of achoice". , , 1991.
  • University of Colorado, "Applied aspects of cutaneous pharmacology". , , 1990.
  • University of California San Diego - Retinoids in malignant and premalignant skin conditions. , , 1990.
  • University of Pittsburgh - Psoriasis treatment, an update. , , 1990.
  • University of Minnesota - "What treatment has told us about the pathogenesis of psoriasis". , , 1990.
  • University of Colorado/Colorado Dermatologic Society, Denver, CO. , , 1989.
  • Columbia University School of Medicine, Dept of Dermatology, New York, NY. , , 1989.
  • New Mexico Dermatology Society, Santa Fe, New Mexico. , , 1988.
  • Yale University Medical School, Dept of Dermatology, New Haven, CT. , , 1988.
  • Harvard University Medical School, Department of Dermatology, Boston, MA. , , 1987.
  • University of California at San Francisco, Department of Dermatology, San Francisco, CA. , , 1987.
  • Roche Laboratories Visiting Lectureship, Department of Dermatology, University of Iowa, Iowa City, IA. , , 1986.
  • Howard Fox Guest Lectureship, Department of Dermatology and Skin and Cancer Unit, New York University Medical Center, New York, NY. , , 1986.
  • Roche Laboratories Visiting Lectureship, Department of Medicine, University of Louisville, KY. , , 1986.
  • Rydelle Laboratories Lectureship, Division of Dermatology, UCLA School of Medicine, Los Angeles, CA. , , 1986.
  • Procter and Gamble Lectureship, University of Cincinnati Medical Center, Department of Dermatology, Cincinnati, OH. , , 1986.
  • Ortho Pharmaceutical Corporation, Division of Clinical Research, Raritan, NJ. , , 1985.
  • Uniformed Services University of the Health Sciences, Departments of Medicine and Pharmacology, Bethesda, MD. , , 1985.
  • University of Illinois Medical School, Department of Dermatology, Chicago, IL. , , 1985.
  • Rydelle Laboratories Lectureship, Department of Dermatology, University of California at San Francisco, CA. , , 1984.
  • Columbia Presbyterian Hospital, Department of Dermatology, New York, NY. , , 1984.
  • University of Michigan Medical School, Department of Dermatology, Ann Arbor MI. , , 1984.
  • Allergan/Herbert Laboratories, Division of Research and Developement, Irvine, CA. , , 1983.
  • University of Illinois College of Medicine, Department of Dermatology, Chicago, IL. , , 1983.
  • University of Colorado School of Medicine, Department of Dermatology, Denver, CO. , , 1983.
  • 5th Korea-Japan Joint Meeting of Dermatology, Chonju Island, Korea. , , 1987.
  • CIRD Symposium, France. , , 1986.
  • Skin Pharmacology Society Meeting, Boston MA. , , 1985.
  • Toxicology Meetings, Stockholm, Sweden. , , 1985.
  • CIRD Symposium, France. , , 1983.
  • Taintor AR, Wong B, Nelson TS, Hansen CB, Papenfuss JS, Panko J, Rakkhit T, Krueger GG, Callis KP. Psoriasis and pruritus: characteristics of disease associated with itch. Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.
  • Leonardi C, Krueger GG, Brodmerkel C, Yeilding N, Zhu Y, Shankar G, Reddy M, Gottlieb AB. Incidence of antibody response to CNTO 1275 in patients with psoriasis. Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.
  • Brimhall AK, Wong B, Capper J, Krausa P, Papenfuss JS, Hansen CB, Panko JM, Nelson T, Krueger GG, Callis KP. HLA-C alleles 0602 and 0701 have opposing effects on severity of psoriasis during pregnancy. Poster session presented at The Society for Investigative Dermatology, Los Angeles. Poster, Presented, 2007.
  • Rakkhit T, Wong B, Nelson TS, Hansen CB, Papenfuss JS, Panko J, Goldgar D, Callis KP, Krueger GG. Time to development of psoriatic arthritis decreases with smoking prior to psoriasis onset and increases with smoking after psoriasis onset. Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.
  • Beasley E, Schrodi SJ, Chang M, Callis KP, Leppert MF, Krueger GG, Begovich AB. Detailed genetic characterization of the psoriasis-associated gene IL12B to further define the causal variant(s). Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.
  • Schrodi SJ, Chang M, Matsunami N, Leppert MF, Krueger GG, Begovich AB. Detailed genetic characterization of the psoriasis-associated gene IL23R. Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.
  • Rakkhit T, Wong B, Nelson T, Hansen CB, Papenfuss JS, Panko J, Goldgar D, Schrodi SJ, Begovich AB, Callis KP, Krueger GG. Association of phenotypic characteristics of psoriasis with the IL-12B and IL-23R psoriasis-risk single nucleotide polymorphisms (SNPs). Poster session presented at The Society for Investigative Dermatology Annual Meeting, Los Angeles. Poster, Presented, 2007.

Languages

  • English, Fluent.

Publications

  • Herron MD, Hinckley M, Hoffman MS, Papenfuss J, Hansen CB, Callis KP, Krueger GG (date unknown). Impact of obesity and smoking on psoriasis presentation and management. Vol. 141, 1527-34. Accepted, .
  • Krueger GG, Chambers DA, Shelby J (date unknown). Involved and uninvolved skin from psoriatic subjects: are they equally diseased? Assessment by skin transplanted to congenitally athymic (nude) mice. Vol. 68, 1548-57. Accepted, .
  • Christensen TE, Callis KP, Papenfuss J, Hoffman MS, Hansen CB, Wong B, Panko JM, Krueger GG (date unknown). Observations of psoriasis in the absence of therapeutic intervention identifies two unappreciated morphologic variants, thin-plaque and thick-plaque psoriasis, and their associated phenotypes. Vol. 126, 2397-403. Accepted, .
  • Krueger GG, Feldman SR, Camisa C, Duvic M, Elder JT, Gottlieb AB, Koo J, Krueger JG, Lebwohl M, Lowe N, Menter A, Morison WL, Prystowsky JH, Shupack JL, Taylor JR, Weinstein GD, Barton TL, Rolstad T, Day RM (date unknown). Two considerations for patients with psoriasis and their clinicians: what defines mild, moderate, and severe psoriasis? What constitutes a clinically significant improvement when treating psoriasis?. Vol. 43, 281-5. Accepted, .
  • Ellis CN, Krueger GG (date unknown). Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes. Vol. 345, 248-55. Accepted, .
  • Soltani-Arabshahi R, Wong B, Feng BJ, Goldgar DE, Duffin KC, Krueger GG (date unknown). Obesity in early adulthood as a risk factor for psoriatic arthritis. Vol. 146, 721-6. Accepted, .
  • Krueger G, Ellis CN (date unknown). Psoriasis--recent advances in understanding its pathogenesis and treatment. Vol. 53, S94-100. Accepted, .
  • Carlin CS, Feldman SR, Krueger JG, Menter A, Krueger GG (date unknown). A 50% reduction in the Psoriasis Area and Severity Index (PASI 50) is a clinically significant endpoint in the assessment of psoriasis. Vol. 50, 859-66. Accepted, .
  • Rakkhit T, Panko JM, Christensen TE, Wong B, Nelson T, Papenfuss J, Hansen CB, Callis-Duffin K, Krueger GG (date unknown). Plaque thickness and morphology in psoriasis vulgaris associated with therapeutic response. Vol. 160, 1083-9. Accepted, .
  • Belman S, Walsh JA, Carroll C, Milliken M, Haaland B, Callis Duffin K, Krueger GG, Feng BJ (date unknown). Psoriasis characteristics for the early detection of psoriatic arthritis. Accepted, .
  • Menter A, Krueger GG, Paek SY, Kivelevitch D, Adamopoulos IE, Langley RG (date unknown). Interleukin-17 and Interleukin-23: A Narrative Review of Mechanisms of Action in Psoriasis and Associated Comorbidities. Vol. 11, 385-400. Accepted, .
  • Coates LC, FitzGerald O, Mease PJ, Gladman DD, Strand V, Goel N, Campbell I, Krueger G, McHugh NJ, Helliwell PS (date unknown). Development of a disease activity and responder index for psoriatic arthritis--report of the Psoriatic Arthritis Module at OMERACT 11. Vol. 41, 782-91. Accepted, .
  • Wojciechowski Z, Pershing LK, Huether S, Leonard L, Burton SA, Higuchi WI, Krueger GG (date unknown). An experimental skin sandwich flap on an independent vascular supply for the study of percutaneous absorption. Vol. 88, 439-46. Accepted, .
  • Duffin KC, Woodcock J, Krueger GG (date unknown). Genetic variations associated with psoriasis and psoriatic arthritis found by genome-wide association. Vol. 23, 101-13. Accepted, .
  • Zhang J, Xu X, Rao NV, Argyle B, McCoard L, Rusho WJ, Kennedy TP, Prestwich GD, Krueger G (date unknown). Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea. Vol. 6, e16658. Accepted, .
  • Krueger GG, Langley RG, Leonardi C, Yeilding N, Guzzo C, Wang Y, Dooley LT, Lebwohl M, CNTO 1275 Psoriasis Study Group. (date unknown). A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. Vol. 356, 580-92. Accepted, .
  • Nair RP, Duffin KC, Helms C, Ding J, Stuart PE, Goldgar D, Gudjonsson JE, Li Y, Tejasvi T, Feng BJ, Ruether A, Schreiber S, Weichenthal M, Gladman D, Rahman P, Schrodi SJ, Prahalad S, Guthery SL, Fischer J, Liao W, Kwok PY, Menter A, Lathrop GM, Wise CA, Begovich AB, Voorhees JJ, Elder JT, Krueger GG, Bowcock AM, Abecasis GR (date unknown). Genome-wide scan reveals association of psoriasis with IL-23 and NF-kappaB pathways. Vol. 41, 199-204. Accepted, .
  • Cargill M, Schrodi SJ, Chang M, Garcia VE, Brandon R, Callis KP, Matsunami N, Ardlie KG, Civello D, Catanese JJ, Leong DU, Panko JM, McAllister LB, Hansen CB, Papenfuss J, Prescott SM, White TJ, Leppert MF, Krueger GG, Begovich AB (date unknown). A large-scale genetic association study confirms IL12B and leads to the identification of IL23R as psoriasis-risk genes. Vol. 80, 273-90. Accepted, .
  • Krueger G, Callis K (date unknown). Potential of tumor necrosis factor inhibitors in psoriasis and psoriatic arthritis. Vol. 140, 218-25. Accepted, .
  • Petersen MJ, Kaplan J, Jorgensen CM, Schmidt LA, Li L, Morgan JR, Kwan MK, Krueger GG (date unknown). Sustained production of human transferrin by transduced fibroblasts implanted into athymic mice: a model for somatic gene therapy. Vol. 104, 171-6. Accepted, .
  • Gilhar A, Krueger GG (date unknown). Hair growth in scalp grafts from patients with alopecia areata and alopecia universalis grafted onto nude mice. Vol. 123, 44-50. Accepted, .
  • Papp KA, Lebwohl MG, Kircik LH, Pariser DM, Strober B, Krueger GG, Berk DR, Navale L, Higham RC (date unknown). The Proposed PASI-HD Provides More Precise Assessment of Plaque Psoriasis Severity in Anatomical Regions with a Low Area Score. (pp. 1079-1083). Vol. 11. Accepted, .
  • Armstrong AW, Blauvelt A, Crowley JJ, Gordon KB, Krueger GG, Krueger JG, Sobell JM, Strober BE, Srivastava B, Menter A (date unknown). Defining drug-free remission of skin disease in patients with plaque psoriasis. (pp. 1484-1487). Vol. 182. Accepted, .
  • Harris KM, Smilek DE, Byron M, Lim N, Barry WT, McNamara J, Garcet S, Konrad RJ, Stengelin M, Bathala P, Korman NJ, Feldman SR, Boh EE, Barber K, Laumann AE, Helfrich YR, Krueger GG, Sofen H, Bissonnette R, Krueger JG (date unknown). Effect of Costimulatory Blockade With Abatacept After Ustekinumab Withdrawal in Patients With Moderate to Severe Plaque Psoriasis: The PAUSE Randomized Clinical Trial. (pp. 1306-1315). Vol. 157. Accepted, .