M. Denise DEARING portrait
  • Distinguished Professor, School Of Biological Sciences

Publications

  • Weinstein SB, Malanga KN, Agwanda B, Maldonado JE & Dearing MD (2020). The secret social lives of African crested rats, Lophiomys imhausi. Journal of Mammalogy. Vol. 101, 1680–1691. Published, 12/2020.
  • Orr TJ, Kitanovic S, Schramm KM, Skopec MM, Wilderman PR, Halpert JR & Dearing MD (2020). Strategies in herbivory by mammals revisited: The role of liver metabolism in a juniper specialist (Neotoma stephensi) and a generalist (Neotoma albigula). Molecular Ecology. Vol. 29, 1674-1683. Published, 04/2020.
  • Martinez-Mota R & Kohl KD, Orr TJ, Dearing MD (2020). Natural diets promote retention of the native gut microbiota in captive rodents. ISME Journal. Vol. 14, 67-78. Published, 01/2020.
  • Martinez-Mota R, Kohl KD, Orr TJ & Dearing MD (2019). Natural diets promote retention of the native gut microbiota in captive rodents. The ISME Journal. Vol. 14, 67-78. Published, 09/2019.
  • Marón CF & Kohl KD, Chirife A, Martino MD, Fons MP, Navarro MA, Beingesser J, McAloose D, Uzal F, Dearing MD, Rowntree VJ, Uhart M (2019). Symbiotic microbes and potential pathogens in the intestine of dead southern right whale (Eubalaena australis) calves. Anaerobe. Vol. 57, 107-114. Published, 06/2019.
  • Stephens SR & Orr TJ, Dearing MD (2019). Chiseling away at the dogma of dietary specialization in Dipodomys microps. Diversity. Vol. 11, 92. Published, 06/2019.
  • Miller AW & Orr TJ, Dearing MD, Monga M. (2019). Loss of Function Dysbiosis Associated with Antibiotics and High Fat, High Sugar Diet. ISME Journal. Vol. 13, 1379-90. Published, 01/2019.
  • Forbey JS, Liu R, Caughlin TT, Matocq MD, Vucetich JA, Kohl KD, Dearing MD, Felton AM. (2018) Review: Using physiologically based models to predict population responses to phytochemicals by wild vertebrate herbivores. Animal. 12:s383-398. https://doi.org/10.1017/S1751731118002264. Published, 12/2018.
  • Kohl KD, Oakeson KF, Orr TJ, Miller AW, Forbey JS, Phillips CD, Dale C, Weiss RB, Dearing MD. (2018) Metagenomic sequencing provides insights into the location of microbial detoxification in the gut of a small mammalian herbivore. FEMS Microbiology Ecology. 94. https://doi.org/10.1093/femsec/fiy184. Published, 11/2018.
  • Kitanovic S, Marks-Fife CA, Parkes QA, Wilderman PR, Halpert JR, Dearing MD. (2018) Cytochrome P450 2B diversity in a dietary specialist—the Red Tree Vole (Arborimus longicaudus). Journal of Mammalogy. 99:578-585. https://doi.org/10.1093/jmammal/gyy039. Published, 05/2018.
  • Kohl KD, Dearing MD, Bordenstein SR. (2018) Microbial communities exhibit host-species distinguishability and phylosymbiosis along the length of the gastrointestinal tract. Molecular Ecology. 27:1874-1883. https://doi.org/10.1111/mec.14460. Published, 04/2018.
  • Miller AW, Orr TJ, Dearing MD, Monga M. (2018) PD03-05 Antibiotics and a high fat/high sugar diet reduce microbial oxalate metabolism in a mouse model. The Journal of Urology. 199:e72 https://doi.org/10.1016/j.juro.2018.02.271. Published, 04/2018.
  • Kohl KD, Varner J, Wilkening JL & Dearing MD (2018). Gut microbial communities of American pikas (Ochotona princeps): evidence for phylosymbiosis and adaptations to novel diets. Journal of Animal Ecology. Published, 03/2018.
  • Kitanovic S, Orr TJ, Spalink D, Cocke GB, Schramm K, Wilderman PR, Halpert JR, Dearing MD. (2018) Role of cytochrome P450 2B sequence vatiation and gene copy number in facilitating dietary specialization in mammalian herbivores. Molecular Ecology. 27:723-736. https://doi.org/10.1111/mec.14480. Published, 02/2018.
  • Kohl KD & Dearing MD (2017). With a little help from my friends: Microbial partners in integrative and comparative biology. Integrative and Comparative Biology. Vol. 57, 669-673. Published, 10/01/2017.
  • Miller AW, Dale C, Dearing MD. (2017) Microbiota diversification and crash induced by dietary oxalate in the mammalian herbivore Neotoma albigula. mSphere. 2:e00428-17. doi: https://doi.org/10.1128/mSphere.00428-17. Published, 10/2017.
  • Miller AW, Dale C & Dearing MD (2017). The induction of oxalate metabolism in vivo is more effective with functional microbial communities than with functional microbial species. mSystems. Vol. 2, e00088-17. Published, 09/26/2017.
  • Kohl KD, Oakeson KF, Dunn D, Meyerholz DK, Dale C, Weiss RB & Dearing MD (2017). Patterns of host gene expression associated with harboring a foregut microbial community. BMC Genomics. Vol. 18, 697. Published, 09/06/2017.
  • Ridenhour BJ, Brooker SL, Williams JE, Van Leuven JT, Miller AW, Dearing MD & Remien CH (2017). Modeling time-series data from microbial communities. Journal of International Society for Microbial Ecology. Vol. 11, 2526–2537. Published, 08/08/2017.
  • Dearing MD & Kohl KD (2017). Beyond Fermentation: Other important services provided to endothermic herbivores by their gut microbiota. Integrative and Comparative Biology. Vol. 57, 723–731. Published, 06/28/2017.
  • Connors PK, Malenke JR, Dearing MD. (2017) Ambient temperature-mediated changes in hepatic gene expression of a mammalian herbivore (Neotoma lepida). Molecular Ecology. 26:4322-4338. doi: 10.1111/mec.14192. Published, 06/2017.
  • Huo L, Liu J, Dearing MD, Szklarz D, Halpert JR, Wilderman PR. (2017) Rational Re-Engineering of the O-Dealkylation of 7-Alkoxycoumarin Derivatives by Cytochromes P450 2B from the Desert Woodrat, Neotoma lepida. Biochemistry. 56:2238-2246. Published, 04/2017.
  • Kohl KD & Dearing MD (2017). Intestinal lymphatic transport: an overlooked pathway for understanding absorption of plant secondary compounds in vertebrate herbivores. Journal of Chemical Ecology. Vol. 43, 290-294. Published, 03/02/2017.
  • Miller AW, Oakeson KF, Dale C & Dearing MD (2016). Microbial community transplant results in increased and long-term oxalate degradation. Microbial ecology. Vol. 72, 470-8. Published, 07/01/2016.
  • Kohl KD, Stengel A & Dearing MD (2016). Inoculation of tannin-degrading bacteria into novel hosts increases performance on tannin-rich diets. Environmental microbiology. Vol. 18, 1720-9. Published, 06/01/2016.
  • Kohl KD, Connelly JW, Dearing MD & Forbey JS (2016). Microbial detoxification in the gut of a specialist avian herbivore, the Greater Sage-Grouse. FEMS microbiology letters. Vol. 363. Published, 06/01/2016.
  • Draft Genome Sequence of an Oxalate-Degrading Strain of Clostridium sporogenes from the Gastrointestinal Tract of the White-Throated Woodrat (Neotoma albigula). Genome Announcements 4(3), pii: e00392-16, doi: 10.1128/genomeA.00392-16. Published, 06/2016.
  • The draft genome sequence and annotation of the desert woodrat Neotoma lepida. Genom Data.9:58-9. doi: 10.1016/j.gdata.2016.06.008. eCollection 2016. Published, 06/2016.
  • Kohl KD, Samuni-Blank M, Lymberakis P, Kurnath P, Izhaki I, Arad Z, Karasov WH & Dearing MD (2016). Effects of Fruit Toxins on Intestinal and Microbial β-Glucosidase Activities of Seed-Predating and Seed-Dispersing Rodents (Acomys spp.). Physiological and biochemical zoology : PBZ. Vol. 89, 198-205. Published, 05/01/2016.
  • Varner J, Horns JJ, Lambert MS, Westberg E, Ruff JS, Wolfenberger K, Beever EA & Dearing MD (2016). Plastic pikas: Behavioural flexibility in low-elevation pikas (Ochotona princeps). Behavioural processes. Vol. 125, 63-71. Published, 03/01/2016.
  • Shah MB, Liu J, Huo L, Zhang Q, Dearing MD, Wilderman PR, Szklarz GD, Stout CD & Halpert JR (2016). Structure-Function Analysis of Mammalian CYP2B Enzymes Using 7-Substituted Coumarin Derivatives as Probes: Utility of Crystal Structures and Molecular Modeling in Understanding Xenobiotic Metabolism. Molecular pharmacology. Vol. 89, 435-45. Published, 03/01/2016.
  • Kurnath P, Merz ND & Dearing MD (2016). Ambient temperature influences tolerance to plant secondary compounds in a mammalian herbivore. Proceedings. Biological sciences. Vol. 283. Published, 01/01/2016.
  • Dizney L & Dearing MD (2016). Behavioural differences: a link between biodiversity and pathogen transmission. Animal behaviour. Vol. 111, 341-347. Published, 01/01/2016.
  • Skopec MM, Kohl KD, Schramm K, Halpert JR & Dearing MD (2015). Using the Specialization Framework to Determine Degree of Dietary Specialization in a Herbivorous Woodrat. Journal of chemical ecology. Vol. 41, 1059-68. Published, 12/01/2015.
  • Moore, Ben D., Wiggins, Natasha L., Marsh, Karen J., Dearing, M. Denise & Foley, William J. (2015). Translating physiological signals to changes in feeding behaviour in mammals and the future effects of global climate change. CSIRO Publishing. Vol. 55(3), 272. Published, 2015.
  • Kohl, K. D., Luong, K. & Dearing, M. D. (2015). Validating the use of trap-collected feces for studying the gut microbiota of a small mammal (Neotoma lepida). Oxford University Press (OUP). Vol. 96(1), 90-93. Published, 2015.
  • Kohl, Kevin D., Cary, Tawnya L., Karasov, William H. & Dearing, M. Denise (2015). Larval exposure to polychlorinated biphenyl 126 (PCB-126) causes persistent alteration of the amphibian gut microbiota: PCB-126 alters the amphibian gut microbiota. Wiley-Blackwell. , n/a-n/a. Published, 2015.
  • Dearing, M. D., Clay, C., Lehmer, E. & Dizney, L. (2015). The roles of community diversity and contact rates on pathogen prevalence. Oxford University Press (OUP). Vol. 96(1), 29-36. Published, 2015.
  • Kohl, Kevin D., Stengel, Ashley & Dearing, M. Denise (2015). Inoculation of tannin-degrading bacteria into novel hosts increases performance on tannin-rich diets: Tannin-degrading bacteria aid hosts consuming tannins. Wiley-Blackwell. , n/a-n/a. Published, 2015.
  • Chirife, Andrea, Dearing, M. Denise, Di Martino, Matías, Kohl, Kevin D., Marón, Carina F. & Rowntree, Victoria J. (2015). Intestinal lactase activity in southern right whale calves ( Eubalaena australis ). Wiley-Blackwell. Vol. 31(1), 398-403. Published, 2015.
  • Lessner KM, Dearing MD, Izhaki I, Samuni-Blank M, Arad Z & Karasov WH (2015). Small intestinal hydrolysis of plant glucosides: higher glucohydrolase activities in rodents than passerine birds. The Journal of experimental biology. Vol. 218, 2666-9. Published, 09/01/2015.
  • Evolutionary irony: evidence that “defensive” plant spines act as a proximate cue to attract a mammalian herbivore. Published, 07/2015.
    http://onlinelibrary.wiley.com/doi/10.1111/oik.020...
  • Too hot to trot? Evaluating the effects of wildfire on patterns of occupancy and abundance for a climate-sensitive habitat specialist. International Journal of Wildland Fire. Published, 06/04/2015.
  • Kohl KD, Pitman E, Robb BC, Connelly JW, Dearing MD & Forbey JS (2015). Monoterpenes as inhibitors of digestive enzymes and counter-adaptations in a specialist avian herbivore. Journal of comparative physiology. B, Biochemical, systemic, and environmental physiology. Vol. 185, 425-34. Published, 04/01/2015.
  • Kohl KD, Cary TL, Karasov WH & Dearing MD (2015). Larval exposure to polychlorinated biphenyl 126 (PCB-126) causes persistent alteration of the amphibian gut microbiota. Environmental toxicology and chemistry / SETAC. Vol. 34, 1113-8. Published, 04/01/2015.
  • Taste and physiological responses to glucosinolates: seed predator versus seed disperser. Published, 11/10/2014.
  • Unique and shared responses of the gut microbiota to prolonged fasting: a comparative study across five classes of vertebrate hosts. FEMS Microbiology Ecology. 90: 883-894. Published, 11/03/2014.
  • Evidence for functional convergence in genes upregulated by herbivores ingesting plant secondary compounds. BMC Ecology. 14:23. Published, 08/15/2014.
  • The importance of biologically relevant microclimate data in species distribution models & habitat suitability assessments. PLoS ONE. 9(8): e104648. Published, 08/12/2014.
  • Gut microbes of mammalian herbivores facilitate intake of plant toxins. Ecology Letters. 17:1238-1246. Published, 07/20/2014.
  • The gastrointestinal tract of the white-throated woodrat (Neotoma albigula) harbors distinct consortia of oxalate-degrading bacteria. Applied Environmental Microbiology. 80:1595-1601. Published, 03/2014.
  • Captivity results in disparate loss of gut microbial diversity in closely related hosts. Conservation Physiology. 2:cou009. Published, 02/13/2014.
    http://conphys.oxfordjournals.org/content/2/1/cou0...
  • Dietary plasticity in pikas as a strategy for atypical resource landscapes. Journal of Mammalogy. 95:72–81. Published, 02/2014.
  • Herbivorous rodents (Neotoma spp.) harbor an abundant and active foregut microbiota. Environmental Microbiology. 16:2869-2878. Published, 01/23/2014.
  • Functional characterization of cytochromes P450 2B from the desert woodrat Neotoma lepida. Toxicology and Applied Pharmacology. 274:393-401. Published, 12/19/2013.
  • Temperature-dependent toxicity in mammals with implications for herbivores: a review. Journal of Comparative Physiology. DOI 10.1007/s00360-012-0670-y. Published, 12/2012.
  • Experience matters: prior exposure to plant toxins enhances diversity of gut microbes in herbivores. Ecology Letters, 15:108-115. Published, 12/2012.
  • Intraspecific Directed Deterrence by the Mustard Oil Bomb in a Desert Plant. Current Biology 22:1-3. Published, 12/2012.
  • Cytochrome P450 2B diversity and dietary novelty in the herbiforous, desert woodrat (Neotoma lepida). PLoS ONE, 7(8):e41510. Published, 12/2012.
  • Estimating duration of infection with avidity assays: Potential limitation and recommendations for improvement. Ecohealth: DOI:10.1007/s10393-012-0742-1. Published, 08/2012.
  • Testing the diet breadth trade-off hypothesis: differential regulations of novel plant secondary compounds by a specialist and generalis herbivore. Oecologia, 168:711-718. Published, 04/2012.
  • Differential expression and activity of catechol-O-Methyl transferase (COMT) in a generalist (Neotoma albigula) and juniper specialist (Neotoma stephensi) woodrat. Published, 11/2011.
  • Using MODIS satellite imagery to predict hantavirus risk. Published, 10/2011.
  • Leptin as a Physiological Mediator of Energetic Trade-offs in Ecoimmunology: Implications for Disease. Published, 10/2011.
  • Induced and constitutive responses of digestive enzymes to plant toxins in an herbivorous mammal. Published, 09/13/2011.
  • Diversity and novelty of the gut microbial community of an herbivorous rodent (Neotoma bryanti). Published, 09/2011.
  • Differential regulation of plant secondary compounds by herbivorous rodent (Neotoma bryanti). Published, 08/08/2011.
  • Lehmer, E.M., J.D. Jones, M.G. Bego, S. St. Jeor, J. Varner, C.A. Clay, and M.D. Dearing (2010) Long-term patterns of immune investment by wild deer mice infected with Sin Nombre virus. Physiological and Biochemical Zoology, 83:847-57. Published, 09/2010.
  • Dearing, M.D. and L. Dizney (2010) Ecology of hantavirus in a changing world. Annals of the New York Academy of Sciences, 1195:99-112. Published, 05/03/2010.
  • Previtali, M.A.; Lehmer,E.M.; Pearce-Duvet, J.M.C.; Jones, J.D.; Clay, C.A.; Wood, B.A.; Ely, P.W.; Laverty, S.M. and , M.D Dearing. (2010) Roles of human disturbance, precipitation, and a pathogen on the survival and reproductive probabilities of deer mice. Ecology, 91:582–592. Published, 02/2010.

Presentations

  • RECOMB: Comparative Genomics, Singapore. Invited Talk/Keynote, Other, 11/2020.
  • Keystone Symposium, Host-microbe Interactions, Singapore. Invited Talk/Keynote, Other, 07/2020.
  • University of Hawaii, Kewalo Marine Station. Presentation, Presented, 11/2019.
  • Sorrobone University, Paris. Presentation, Presented, 10/2019.
  • The Wildlife Society: Symposium Speaker. Invited Talk/Keynote, Presented, 09/2019.
  • Ecological & Evolutionary Genomics Gordon Conference. Invited Talk/Keynote, Presented, 07/2019.
  • American Society of Mammalogists, Plenary Talk . Invited Talk/Keynote, Presented, 07/2019.
  • Animal- Microbe Symbioses Gordon Conference Invited Discussion Leader. Invited Talk/Keynote, Presented, 06/2019.
  • Utah Valley University, UT. Presentation, Presented, 03/2019.
  • Cal State University Northridge. Invited Talk/Keynote, Presented, 11/2018.
  • Université Pierre et Marie Curie-CNRS, Observatoire Océanologique de Banyuls sur mer, France . Invited Talk/Keynote, Presented, 10/2018.
  • Boise State University. Invited Talk/Keynote, Presented, 09/2018.
  • Utah State University. Invited Talk/Keynote, Presented, 04/2018.
  • Eating and Not Dying: Strategies for Thriving on a Diet of Toxins, University of Nevada, Reno . Invited Talk/Keynote, Presented, 02/22/2018.
  • Microbiome-enabled detoxification in a novel mammalian system and potential applications to human health. University of California San Francisco . Invited Talk/Keynote, Presented, 01/31/2018.
  • University of Sydney, Sydney, Australia. Invited Talk/Keynote, Presented, 11/2017.
  • Australian National University, Canberra Australia . Invited Talk/Keynote, Presented, 11/2017.
  • EEB Thursday Seminar: Eating and not dying: How herbivores deal with plant toxins, University of Michigan . Invited Talk/Keynote, Presented, 10/2017.
  • Gut microbes facilitate the ingestion of dietary toxins by wild herbivores, University of California, Irvine, Ecology and Evolution Department . Invited Talk/Keynote, Presented, 09/2017.
  • Southern California Microbiome Symposium, University of California, Irvine . Invited Talk/Keynote, Presented, 09/2017.
  • Society for Integrative and Comparative Biology Symposium Speaker . Invited Talk/Keynote, Presented, 01/2017.
  • American Society for Microbiology, Plenary talk. Invited Talk/Keynote, Presented, 07/2016.
  • UC Berkeley, Museum Vertebrate Zoology. Invited Talk/Keynote, Presented, 07/2016.
  • Dimensions of Biodiversity, NSF. Invited Talk/Keynote, Presented, 07/2016.
  • UC Berkeley, Museum Vertebrate Zoology. Invited Talk/Keynote, Presented, 07/2016.
  • University of Wisconsin, Madison. Invited Talk/Keynote, Presented, 07/2016.
  • Joint Meeting of the International Congress of Zoology and Zoological Society of Japan, Okinawa, Japan . Invited Talk/Keynote, Presented, 06/2016.
  • Université Pierre et Marie Curie-CNRS, Observatoire Océanologique de Banyuls sur mer, France. Invited Talk/Keynote, Presented, 06/2016.
  • Brigham Young University, Provo UT. Invited Talk/Keynote, Presented, 03/2016.
  • Texas Tech, Department of Biology. Invited Talk/Keynote, Presented, 12/2015.
  • Cal State Fullerton, Department of Biology . Invited Talk/Keynote, Presented, 10/2015.
  • University of Nevada, School of Life Sciences. Invited Talk/Keynote, Presented, 07/2015.
  • University of Utah, Microbial Pathogenesis Seminar Series. Invited Talk/Keynote, Presented, 06/2015.
  • The Ohio State University, Department of Evolution, Ecology and Organismal Biology. Invited Talk/Keynote, Presented, 05/2015.
  • Gordon Conference, Animal Microbe Symbiosis, Symposium Speaker. Invited Talk/Keynote, Presented, 04/2015.
  • American Society of Mammalogists, Plenary talk. Invited Talk/Keynote, Presented, 02/2015.
  • P20 Urology Centers Directors, NIDDK. Invited Talk/Keynote, Presented, 12/2014.
  • University of Tennessee, Knoxville, TN . Invited Talk/Keynote, Presented, 06/2013.
  • Entrada Institute, Torrey, UT. Invited Talk/Keynote, Presented, 06/2013.
  • University of Missouri: Life Science Week Speaker . Invited Talk/Keynote, Presented, 06/2013.
  • American Society of Mammalogists, Invited Symposium Speaker, University of Arizona, Tucson, AZ. Presentation, Presented, 10/2012.

Research Groups

  • Sara Weinstein, Postdoc. 07/01/2018 - present. Awards/Scholarships/Stipends: Sara received a Smithsonian fellowship and a pathogenesis fellowship.